retina

27 May 2016
27- 28 MAY 2016
GOA
RETINA
M
A
R
G
O
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GENOVA
FIN
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A
Palazzo Ducale is a historical building that throughout the centuries was
regarded as the seat of power of the Republic and the Doge’s residence.
The first parts of the Palace were built between 1251 and 1275, during
the flourishing period of the Republican history of Genoa, while the Torre
Grimaldina (also named “Torre del Popolo” - Tower of the People) was
completed in 1539.
On the main floor, the so-called Piano Nobile, are the frescoed halls of the
Maggior and Minor Consiglio, where many public events take place.
Palazzo Ducale was restored in 1992, in occasion of the celebrations of
Christopher Columbus and the 500th anniversary of the discovery of America.
The palace is today not only a historical building but also a museum and a
centre for cultural events and arts exhibitions, the beating heart of cultural
and social activities of Genoa and its territory.
In July 2001 the Palace hosted the G8 Summit, which was attended by the
leaders of Canada, France, Germany, Italy, Japan, Russia, United Kingdom
and United States.
Dear Friends and Colleagues,
We are delighted to welcome you to the GOA_retina Course in Genova.
Main topics include degenerative and vascular disease of the retina, macula
and vitreo both medical and surgical, from the bed to the benchmark.
High-tech imaging, diagnostic techniques, different treatment approaches
and new insights on angiogenesis from basic science will be the focus of the
discussion.
We do wish you a productive Course and a wonderful free time in Genova,
Carlo Enrico Traverso
Matteo Badino
WELCOME LETTER
Massimo Nicolò
Board and Faculty
page 3
General Information
page 4
Scientific Information
page 6
Scientific Program
- 27 May 2016
- 28 May 2016
page 7
page 9
Patronagespage 11
Acknowledgementspage 12
CONTENTS
Company Profiles
2
page 14
President
Carlo Enrico Traverso
Course Director
Massimo Nicolò
Scientific Secretariat
Matteo Badino
Teresio Avitabile - Catania
Massimo Nicolò - Genoa
Claudio Azzolini - Varese
Giacomo Panozzo - Verona
Matteo Badino - Genoa
Barbara Parolini - Brescia
Maurizio Battaglia Parodi - Milan
Mariacristina Parravano - Rome
Luigi Borgia - Genoa
Grazia Pertile - Negrar
Francesco Boscia - Sassari
Luisa Pierro - Milan
Susan Bressler - Baltimore (USA)
Alessandra Puddu - Genoa
Felice Cardillo Piccolino - Genoa
Giuseppe Querques - Milan
Gilda Cennamo - Naples
Michele Reibaldi - Catania
Davide Croce - Castellanza
Federico Ricci - Rome
Chiara Eandi - Turin
Stanislao Rizzo - Florence
Ettore Ferrari - Imperia
Raffaella Rosa - Genoa
Andrea Giani - Milan
Tommaso Rossi - Genoa
Alfonso Giovannini - Ancona
Leopold Schmetterer - Vienna (Austria)
Michele Iester - Genoa
Peter Stalmans - Leuven (Belgium)
Ugo Introini - Milan
Giovanni Staurenghi - Milan
Silvio Lai - Genoa
Carlandrea Trillo - Genoa
Leonardo Mastropasqua - Chieti
Francesco Viola – Milan
Donatella Musetti - Genoa
Stela Vujosevic - Padua
Piergiorgio Neri - Ancona
3
BOARD AND FACULTY
Faculty
Organizing Secretariat
Viale Giacomo Matteotti, 7
50121 Florence - Italy
Tel. +39 055 50351
Fax +39 055 5001912
[email protected]
Registration Desk
The Registration Desk in the Loggiato Maggiore of Palazzo Ducale will be open
for registration and information according to the following schedule:
Friday 27 May from 7.30 to 18.00
Saturday 28 May
from 8.00 to 16.30
Participants are kindly requested to collect their Course kit and name badge.
New registrations are also possible at this desk.
Course Venue
Palazzo Ducale
Piazza Giacomo Matteotti, 9
16123 Genoa - Italy
Name Badge
Each participant will receive a name badge upon check-in at the registration
desk. The badge will be the official Course pass and should be worn at all time
in order to gain entry into the meeting room.
GENERAL INFORMATION
Registration Fees
Fees (VAT included)
On site
Delegates
€ 330,00
Residents, COT, Nurses* € 90,00
* Proof of status is mandatory.
4
Registration fees include:
• Attendance to all scientific sessions
• Coffee breaks
• Light lunch on 27 and 28 May
• Course kit and name badge
• Certificate of attendance
• CME Kit
Catering on Site
Coffee breaks during the Course and the light lunch on 27 and 28 May are
included in the registration fees.
Certificate of Attendance
Regularly registered participants will receive a certificate of attendance.
Insurance
The Course Organizers do not assume any liability for personal injuries
sustained or loss of, or damage to property belonging to Course participants
(or their accompanying persons), either during or as result of the Course.
Participants are requested to make their own arrangements with respect to
health and travel insurance before departing from their home country.
Wi-Fi
Free Wi-Fi Internet connection is available in the plenary room and common
areas of the Course venue.
5
GENERAL INFORMATION
Language
The official language of the GOA_retina Course is English. All participants are
encouraged to join discussions, independently of their fluency in English, as the
exchange of ideas and critical evaluation of presentations is the main purpose
of the Course. Simultaneous translation into Italian will be provided during the
sessions in the plenary room.
SCIENTIFIC INFORMATION
CME CREDITS (only for Italian participants)
I crediti formativi ECM saranno certificati dal Provider OIC srl (n. 2836) secondo il
nuovo regolamento approvato dalla Commissione Nazionale per la Formazione
Continua il 13 gennaio 2010. L’accreditamento del Congresso sarà effettuato
per l’intero evento in un’unica soluzione
I crediti assegnati al Corso sono 2,6 e sono rivolti a Medici Specialisti in
Oftalmologia, Medici di Medicina Generale, Ortottisti/Assistenti di Oftalmologia,
Farmacisti e Infermieri.
La presenza al Corso sarà certificata dalla firma dei registri all’entrata e all’uscita
giorno per giorno. L’assenza di una sola delle firme necessarie determinerà
l’impossibilità di assegnazione dei crediti.
Per completare l’acquisizione dei crediti il partecipante dovrà compilare
l’apposita modulistica da ritirare presso il Registration Desk, comprensiva di
scheda anagrafica e certificazione di autoapprendimento nonché il questionario
di valutazione dell’evento da compilarsi in forma anonima.
Slide Centre
The Slide Centre is situated in Sala del Minor Consiglio. The plenary room is
equipped with a computer slide projector alone, and no traditional slide or
overhead projectors for transparencies are available.
It will be not possible to use personal laptops in the meeting room. Speakers
are kindly requested to use “PowerPoint” (Windows or OS X Apple) or Keynote
for their presentations. The dimensions of the presentation should not exceed
300 MB, videos included.
Please use “.gif ” and “.jpg” extensions for images. Other types of extensions will
be accepted provided they can be recognized by PowerPoint / Keynote.
The use of CD-Rom, pens or memory stick is advisable to ease downloading of
presentations, and same should be handed to technicians at the Slide Centre in
good time. Please remember to collect your CD or memory pen from the Slide
Centre at the end of the session.
Speakers with presentations on CD Rom or memory pen: please
report to the Slide Centre at least one hour before your presentation or the day
before if you are scheduled to speak in the morning.
Speakers with presentations on personal laptops: please report to the Slide
Centre at least four hours before your presentation or the day before, if scheduled in the morning.
This timing will allow your presentation to be downloaded onto the main computer.
6
27 May 2016
9.00 Session I - MACULAR IMAGING AND BASIC SCIENCES
13.00 Chairman: Felice Cardillo Piccolino
Moderators: Luigi Borgia, Michele Iester, Massimo Nicolò
9.00Definition of the retinal layers using a common terminology
Giovanni Staurenghi
9.20Swept-source angio-OCT basics and definition of a new OCT
generation
Raffaella Rosa
9.40 Angio-OCT basics and definition
Gilda Cennamo
10.00 Back to basic science. VEGF and PlGF
Alessandra Puddu
10.20
KEYNOTE LECTURE
Protocol T: news, results and practical implications
Susan Bressler
10.50 OPENING CEREMONY
11.20 Coffee break
Chairman: Giovanni Staurenghi
Moderators: Teresio Avitabile, Ettore Ferrari
12.20 Read and understand the pathologic signs at angio-OCT
Luisa Pierro
12.40Management of exudative maculopathy: a focus on idiopathic polypoidal
choroidal vasculopathy
Alfonso Giovannini
13.00 Light lunch
7
SCIENTIFIC PROGRAM
11.50 KEYNOTE LECTURE
The pipeline in diagnosis. What do we expect
Leopold Schmetterer
27 May 2016
14.00 Session II - IMPROVEMENT IN VITREO-RETINAL SURGERY
18.00Chairman: Stanislao Rizzo
Moderators: Matteo Badino, Silvio Lai, Carlandrea Trillo
14.00 Improvements in vitrectomy instrumentation
Tommaso Rossi
14.20 Imaging the vitreoretinal interface with new generation OCT
Michele Reibaldi
14.40 High-res imaging of the macula after translocation
Grazia Pertile
15.00 Myopic traction maculopathy
Francesco Viola
15.20 KEYNOTE LECTURE
Inner limiting membrane peeling: is it worth?
Leonardo Mastropasqua
15.50 Coffee break
16.10 Prognostic factors in macular pucker
Matteo Badino
16.30 The surgery of diabetic macular edema: why and when
Francesco Boscia
SCIENTIFIC PROGRAM
16.50 Epiretinal prosthesis indications, techniques and results
Stanislao Rizzo
17.10 High-res imaging of macular buckling
Barbara Parolini
17.30 KEYNOTE LECTURE
Episcleral surgery vs. vitrectomy
Teresio Avitabile
8
28 May 2016
9.00Session III - HOW ANGIO-OCT, HIGH-RES IMAGING, NEW LASER
13.30TECHNOLOGY AND PHARMACOTHERAPY WILL CHANGE THE WAY WE MANAGE RETINAL DISEASES
Chairman: Giuseppe Querques
Moderators: Ugo Introini, Massimo Nicolò
9.00 The evolution of laser photocoagulation: once upon a time the argon
Chiara Eandi
9.15 Subthreshold laser: basics and clinical results
Stela Vujosevic
9.30 KEYNOTE LECTURE
Retinal pigment epithelium and surroundings
Felice Cardillo Piccolino
10.00 Adaptive optics
Mariacristina Parravano
10.15 Retinal vein and arterial occlusion
Maurizio Battaglia Parodi
10.30 Central serous chorioretinopathy
Massimo Nicolò
10.45
The burden of macular disease in ageing Europe: costs vs human
suffering
Davide Croce
11.05Discussion
11.35 KEYNOTE LECTURE
New frontiers for enzymatic vitreolysis: indications and results
Peter Stalmans
12.05Choroiditis
Piergiorgio Neri
12.20 Wet AMD
Giuseppe Querques
9
SCIENTIFIC PROGRAM
11.15 Coffee break
28 May 2016
9.00Session III (cont.)
13.30
12.35 Atrophic AMD
Andrea Giani
12.50 DME and diabetic retinopathy
Federico Ricci
13.05 e-health in vitreoretinal disease
Claudio Azzolini
13.20Discussion
13.30 Light lunch
14.30Session IV - WORKSHOP ON DRUG DELIVERY SYSTEM OF STEROIDS
16.30 IN DIABETIC MACULAR EDEMA
Chairmen: Giuseppe Querques, Stela Vujosevic 14.30 Role of inflammation in DME
Stela Vujosevic
14.45 Anatomic and functional improvement: 3 years of the MEAD study
Giuseppe Querques
15.00 The FAME study
Donatella Musetti
SCIENTIFIC PROGRAM
15.15Towards a treatment algorithm
Maria Cristina Parravano
15.30Dexamethasone intravitreal implant at the time of cataract surgery in
patients with diabetic macular edema
Giacomo Panozzo
15.45Changing indications in the vitrectomized patient
Matteo Badino
16.00Real-life in the management of DME patients
Massimo Nicolò
16.15 Discussion
16.30 Closure of the Course
10
PATRONAGES
Under the Patronage of
11
ACKNOWLEDGEMENTS
The GOA_retina Course would like to acknowledge
the generous support of the following companies:
12
ALCON ITALIA spa
Category: Chemical - Pharmaceutical
Viale G. Richard, 1/B - 20143 Milano
Tel. +39 02818031 - Fax +39 028910550
Alcon aims to be the first choice in eye care sector, by providing innovative products which improve
the quality of your sight and life. Alcon is composed by three franchises. Surgical, global leader in
the area of ophthalmology surgical tools. Pharma: which offers a broad selection of pharmacological treatments for eye diseases. Vision Care: leader in the contact lenses market.
ALLERGAN PHARMACEUTICAL IRELAND
Category: Medicines and Medical Devices
Therapeutic area: Ophtalmology
Via Salvatore Quasimodo, 134-136 - 00144 Roma
Tel.+39 0650956-1
[email protected] - www.allergan.it
Allergan is committed to the development of products for the treatment of numerous eye diseases
including glaucoma, dry eye, macular oedema. Our company is based on engagement with our
clients and collaboration with doctors and patients, to provide the most innovative treatments and
to increase access to therapies. Our growth is the result of investment in research and development,
thanks to an annual investment of 1,7 billion dollars.
BAYER
Category: Pharmaceutical
Viale Certosa 130 - 20156 Milano
Tel.+39 0239782222 - Fax +39 023978444
www.bayer.it
Bayer is a global company based on innovation, with key competences in Life Sciences, Healthcare
and Agriculture. Bayer’s scientific research and innovative products are finalized to improve people’s life quality everywhere in the world, according to the company’s mission: Science for a Better
Life.
COMPANY PROFILES
MAGENTA FARMACEUTICI
Category: Pharmaceutical
Account Marcello Selvaggio
Via Leonardo da Vinci, 154 - 20090 Trezzano sul Naviglio (MI)
Tel. +39 0245101815 - Fax +39 0245108571
[email protected] - www.magentafarmaceutici.com
Magenta Farmaceutici is a new Italian company within the ophthalmology sector. Its headquarters
are located in Milan and it collaborates with managers who have been working in multinational
companies for years. On the Italian territory there are 15 Key Account Retina that are very competent and appreciated for the work which is carried out. Magenta has an ambitious program to
develop new products and new ophthalmology devices, by collaborating with important European
societies.
14
NICOX FARMA srl
Category: Pharmaceutical
Account Francesca Beccalli
Via Ludovico Ariosto, 21 - 20091 Bresso (MI)
Tel. +39 0261036304 - Fax +39 0284980031
[email protected] - www.nicox.it
Nicox is a new international ophthalmic company, aiming to build a diversified portfolio of therapeutic products addressing the needs of eyecare practitioners and patients around the world. Nicox S.A. is the parent company of the Nicox Group and is based in France. Nicox S.A. has a number
of international subsidiaries, including three subsidiaries coming from external growth operations.
Nicox Farma (previously called EuPharmed) is Nicox’s Italian commercial subsidiary. Nicox completed the acquisition of EuPharmed in December 2013. Nicox Farma commercializes a broad portfolio of ophthalmic pharmaceutical products, medical devices and nutraceuticals in Italy.
NOVARTIS
Category: Pharmaceutical
Largo Umberto Boccioni, 1
21040 Origgio - Varese
Tel. +39 0296541 - Fax +39 0296542910
www.novartis.it
OOgroup
Category: Pharmaceutical
C. Da Molino, 17 - 63833 Montegiorgio (FM)
Tel. +39 0734964096 - Fax +39 0734964551
[email protected] - www.oogroup.it/sooft/home.php
OOgroup is an Italian pharmaceutical group specialized in research and development of dietary
supplements, medical devices and medical specialities dedicated to eye care. Retina is one of the
areas in which OOgroup is more engaged in. In particular, SOOFT and BIOOS division have been
dedicating for a number of years the development of specific formulations based on natural ingredients able to prevent and delay the progression of degenerative diseases, such as diabetic
retinopathy and age-related macular degeneration. SOOFT and BIOOS products aim especially
to strengthen the eye microcirculation to prevent and delay retinal haemorrhages and to facilitate
the retina’s normal functioning. The OOgroup companies have been pioneers, both in Italy and in
Europe, in the area of supplementary feeding aimed at primary and secondary prevention of the
most widespread and potentially debilitating retinal diseases.
15
COMPANY PROFILES
Novartis was founded in 1996, through the merger of Ciba-Geigy and Sandoz, and inherited their
historically leading role in the pharmaceutical sector. Since the beginning, the new Group proved
itself to be one of the major and most innovative protagonists in the healthcare sector and has
been responsible for some of the main pharmaceutical breakthroughs of the last years, such as the
development of the first ‘target therapy’ in oncology. Today Novartis is one of the world’s leaders
in the healthcare area , and one of the most important players in each of the sectors in which operates: innovative medicines, eye care products, generics and biosimilars. The companies of the
Group employ approximately 118,000 full-time-equivalent associates and Novartis’s products are
available in more than 180 Countries around the world. The company has a consolidated presence
in Italy and plays a leading role in all the major therapeutic areas of the Italian pharmaceutical market: cardio-metabolic, immunology and dermatology, neuroscience, ophthalmology, oncology and
hematology, respiratory.Its headquarters is in Origgio, in the province of Varese. In Italy Novartis is
also a highly prominent production company, relying on two large manufacturing sites whose activities are directed to the international markets: Torre Annunziata (NA) and Rovereto (TN).
SANTEN ITALY srl
Category: Pharmaceutical - Medical Devices
Via Roberto Lepetit, 8/10 - 20124 Milano
Tel. +39 026200191 - Fax +39 0262001999
[email protected] - http: //santen.eu/it
Santen is a specialized pharmaceutical company exclusively engaged in the ophthalmic
sector. Firstly, Santen achieved a prominent role in the market of ophthalmic preparations in Japan,
then it expanded worldwide. Santen has been present in Europe for over
20 years and in Italy since 2014. It continues to strengthen its presence in many other countries to
guarantee that patients and health professionals have access to their innovative treatments.
ments.
SIFI - Società Industria Farmaceutica Italiana spa
Category: Pharmaceutical
Account Elisa Vecchio
Via Ercole Patti, 36 - 95025 Aci S. Antonio (CT)
Tel. +39 0957922111 - Fax +39 0957922224
[email protected] - www.sifigroup.com
SIFI is the leading Italian ophthalmic company, focused on eye care since its foundation in 1935.
SIFI designs, manufactures and markets innovative pharmaceutical products, surgical and medical
devices. Headquartered in Catania (Sicily), SIFI operates directly in Italy, Romania and Mexico with a
staff of more than 330 people worldwide. Since June 2015 SIFI is backed by 21 Investimenti, private
equity firm founded by Alessandro Benetton, to support the company’s international expansion and
portfolio development strategy.
TECNO INSTRUMENTS srl
Category: Medical Instruments and Medical Devices
Account Elena Turchi
Strada Traversante San Leonardo 13/A - 43122 Parma
Tel. +39 0113855962 - Fax +39 011334484
[email protected] - www.tecnoinstruments.it
COMPANY PROFILES
Tecno Instruments srl is a distributor of medical equipment and devices (also disposable) for eye surgery and diagnostics. Tecno Instruments srl is working in Piemonte,
Valle d’Aosta, Lombardia and Liguria.
16
THÉA FARMA spa
Category: Pharmaceutical
Account Caterina D’Alessandro
Via Giotto, 36 - 20145 Milano
Tel. +39 0236764322
[email protected]
Thea Farma is the Italian branch of Laboratoires Théa, the first European independent
pharmaceutical company specialized in ophthalmology. Our mission is to meet ophtalmologists and patients’ needs, by offering a broad portfolio of products in several therapeutic areas: treatment and prevention of AMD (DMLE), dry eye, glaucoma, eye infections and inflammations, allergy and products for the surgical practice. Thea Farma
offers cutting-edge technologies (ABAK® System) to ensure products preservation without using preservatives which can damage the ocular surface.
TOPCON ITALIA
Category: Medical Instruments and Medical Devices
Viale dell’Industria, 60 - Paderno Dugnano (MI)
Tel. +39 029186671
[email protected] - www.topcon.it
Topcon, founded in Tokyo in 1932, is a multinational company which includes over 60 affiliated companies and subsidiaries located all over the world. Topcon’s brand is known
and appreciated worldwide as a global leader in the production and sale of diagnostic
instrumentation and high quality software for ophthalmology and ptometry: Topcon’s
products are renowned in the field of ophthalmology for their quality, reliability and
performance. The source of Topcon’s strength is research, development and continual
improvement of innovative products, by providing the top quality service that its exigent
customers expect from them.
Visufarma spa is a pharmaceutical society founded in 1996 in Rome with the purchase of
some products of MSD Italia. Widening its products portfolio, it became one of the main
Italian pharmaceutical – ophthalmic firms. Nowadays it places on the market 35 products
for several eye pathologies and diseases. Over the last years, thanks to 2 products patented at EU level, it started internationalising its ophthalmic portfolio, by signing commercial agreements with firms operating outside Italy. Recently Visufarma started operating
in dermatology and it is currently marketing 8 products in this area and it also has 6
generic medicine products in its portfolio.
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COMPANY PROFILES
VISUFARMA spa
Category: Pharmaceutical
Via Canino, 21 - 00191 Roma
Tel. +39 0636306842
[email protected] - www.visufarma.it
WE HELP MILLIONS OF PEOPLE
SEE THE WORLD BETTER
OUR VISION
To be the most trusted
leader in eye care
OUR MISSION
To provide innovative
products that enhance
quality of life by helping
people see better
OUR VALUES
• Focus on eye care
• High quality, innovative products
• Partnership with eye care
professionals
• High-performance teams
MPXXX.XX.16
PER MOLTI NON
LA VITA ATTIVA POSSIAMO
TERMINA TROPPO PRESTO ACCETTARLO
Entro il 2050 la popolazione over 60
raggiungerà i due miliardi di individui
nel mondo, rendendo la lotta alle
malattie legate all’età una sfida ancora
più grande.
Aiutiamo le persone a rimanere più
sane e attive in età avanzata, sia con
trattamenti mirati contro il cancro e
le malattie cardiovascolari, sia con
soluzioni per malattie oculari e
terapie per i malati di artrite. La vita
non dovrebbe fermarsi a 60 anni.
Per scoprire come le nostre
innovazioni stanno aiutando a
migliorare la vita delle persone,
visita il sito www.bayer.com/ari.