XVI WORKSHOP ON PHARMACOBIOMETALLICS 28‐29 Ottobre

XVI WORKSHOP ON PHARMACOBIOMETALLICS
28‐29 Ottobre 2016
PROGRAMMA
Venerdi, 28 Ottobre 2016
12.30 Registrazione dei Partecipanti (Royal Palace Hotel)
14.45 Saluti delle Autorità
Chairman: Prof. Giovanni Natile, Prof. Luigi Monsù Scolaro
15.00 Lorenzo Polenzani “Fostering innovation by industry-academia collaborative models”
Diagnostici Innovativi in Oncologia e Malattie Cardiovascolari
15.50 OC 1 S. Banfi “Sintesi di una serie di fotosensibilizzanti della famiglia dei BODIPY, loro
applicazione in campo antitumorale e antibatterico”
16.10 OC 2 Marco Lelli “Electrodeposition of nanostructured biomimetic hydroxyapatite with
antibacterial property for innovative applications “
16.30 Coffee Break
16.50 OC 3 Antonio Rosato, “Unravelling Ag toxicity mechanisms: Cu+ transport proteins interacting
with AgNPs and Ag+ ions ”
17.10 OC 4 Nicoletta Depalo “Superparamagnetic iron oxide nanoparticles as sorafenib delivery
vector for magnetically targeted therapy of hepatocellular carcinoma ”
17.30 OC 5 Lorena Cucci “Gold nanoparticles decorated with angiogenin-mimicking peptide
fragments for cancer therapy applications ”
17.50 OC 6 Enzo Terreno “MRI detection of the release of doxorubicin from liposomes triggered by
non thermal effects of ultrasound”
18.10 OC 7 Piersandro Pallavicini “Monolayers of non-spherical noble metal nanoparticles:
antibacterial surfaces with photothermal, chemical, and chemo-photothermal action ”
18:30 Consiglio Scientifico C.I.R.C.M.S.B.
19:00 Consiglio Scientifico C.I.R.C.M.S.B
Sabato, 29 Ottobre 2016
Ruolo degli Ioni Metallici nelle Patologie Degenerative Croniche
Chairman: Dr. Michele Saviano
9.00 OC 8 Francesco Bellia “Site-specific modulators of Aß clearance by IDE ”
9.20 OC 9 Giuseppe Grasso “The role of Amyloid beta protein, metal ions and oxidative stress in the
pathophysiology of Alzheimer’s disease: recent findings “
9.40 OC 10 Daniela Valensin “Bifunctional chelators for potential treatment of Alzheimer's disease
”
10:00 OC 11 Valentina Oliveri “Modulators of copper-induced protein aggregation”
10.20 OC 12 Michele Maffia “Copper in human physiology and pathology ”
10.40 OC 13 Alessia Munzone “Terminal Peptide Fragments of Angiogenin protein binding to
copper: a study on the coordination”
11.00 Coffee Break
Nuovi farmaci inorganici in oncologia
Chairman: Prof. Ennio Zangrando
11.20 OC 14 Elena Michelucci “Mass spectrometry and metallomics: stability and binding site
location in the Cyt c-CDDP model system”
11.40 OC 15 Alessandro Pratesi “Oxaliplatin analogues bearing different halide ligands as promising
candidates for colorectal cancer treatment: a comparison of chemical and biological profiles “
12.00 OC 16 Federica Porta “An oxadiazole Pt(II) complex with promising in vivo antitumor activity
”
12:20 OC 17 Marianna Pioli “A novel approach for the development of antimycotoxicogenic
compounds”
12.40 OC 18 Michele Benedetti “Metalated nucleotides can be substrates for cell enzymes and
transporters: Relevance for metal toxicity and the development of new metal based drugs”
13:00 Pranzo (Royal Palace Hotel)
14.30 Sessione poster
Nuovi Farmaci –Inorganici in Oncologia
Chairman: Prof. Francesco Paolo Fanizzi
15.30 OC 19 Nicola Margiotta “Kiteplatin antitumor efficacy enhanced by Pt(IV) prodrugs and/or
nanoparticle encapsulation”
15.50 OC 20 Luigi Messori “Proteomic studies on cytotoxic gold compounds: the search of the
underlying molecular mechanisms”
16.10 OC 21 Elisabetta Gabano “The octahedral assembly of the Pt(IV) anticancer prodrugs: a source
of opportunities “
16.30 OC 22 Tiziano Marzo “Triethylphosphine gold iodide (I), the iodido analogue of Auranofin:
comparative studies of a potential antineoplastic agent ”
16.50 Coffee Break
Chairman: Prof. Graziella Vecchio
Radiofarmaci nella Diagnostica e Terapia Tumorale
17.10 OC 23 Laura Zaccaro “[99mTc(N)PNP43]-labelled RGDechi peptide: a new radiotracer for the
selective SPECT Imaging of αvβ3 integrin expression”
Biomateriali e Biocristallografia
17.30 OC 24 Michela Reggi “Influence of intra-skeletal coral components on calcium carbonate
precipitation”
Metalloproteine come Catalizzatori Biologici
17.50 OC 25 Simona Fermani “Unravelling the shape and structural assembly of photosynthetic
GAPDH/CP12/PRK complex from Arabidopsis thaliana by X-ray diffraction and small angle X-ray
scattering ”
18.10 OC 26 Massimiliano Coletta “The interaction of cytochrome c with cardiolipin and its
functional and structural effects “
20:30 Cena sociale (Royal Palace Hotel)