4Th Annual EMSCO meeting

FACULTY
GENERAL INFORMATION
Lionel Adès Paris, France
Enrico Balleari Genoa, Italy
Nicolas Bonadies Bern, Switzerland
Mario Cazzola Pavia, Italy
Fatiha Chermat Paris, France
Daniela Cilloni Orbassano-TO, Italy
Dominic Culligan Aberdeen, United Kingdom
Matteo Giovanni Della Porta Rozzano-MI, Italy
Pierre Fenaux Paris, France
Michaela Fontenay Paris, France
Ulrich Germing Düsseldorf, Germany
Aristoteles Giagounidis Düsseldorf, Germany
Daniela Gioia Alessandria, Italy
Silke Gloaguen Dresden, Germany
Katharina Götze München, Germany
Detlef Haase Göttingen, Germany
Olivier Hermine Paris, France
Wolf-Karsten Hofmann Mannheim, Germany
Anna Jonasova Prague, Czech Republic
Austin Kulasekararaj London, United Kingdom
Alessandro Levis Alessandria, Italy
Luca Malcovati Pavia, Italy
Hind Medyouf Frankfurt, Germany
Esther Oliva Reggio Calabria, Italy
Francesco Onida Milan, Italy
Sophie Park Grenoble, France
Uwe Platzbecker Dresden, Germany
Valeria Santini Florence, Italy
Guillermo Sanz Valencia, Spain
Rebekka Schneider-Kramann Aachen, Germany
Eric Solary Villejuif, France
Ana Belén Valencia Martínez Florence, Italy
Aart Anne van de Loosdrecht Amsterdam, Netherlands
Norbert Vey Marseille, France
Francesca Vinchi Heidelberg, Germany
Maria Teresa Voso Rome, Italy
Meeting Venue
Aula Magna
Università degli Studi di Firenze
Piazza S. Marco, 4
50121 – Florence, Italy
Scientific Committee
Prof. Valeria Santini (Florence – IT)
Prof. Pierre Fenaux (Paris – FR)
Prof. Uwe Platzbecker (Dresden – GER)
4Th Annual EMSCO meeting
Official Language
English.
Badge
All registered participants and speakers will be
given a badge which they must wear to be
admitted to the scientific sessions.
Attendance
certificate
A certificate will be given to all participants at
the end of the meeting.
Changes
Parts of the program may be
changed without notice.
Organizing Secretariat
Studio E.R. Congressi
Via Marconi, 36
40122 Bologna
- Italy
Phone +39 051 4210559
Fax +39 051 4210174
E-mail: [email protected]
www.ercongressi.it
Scientific Secretariat
EMSCO
European MDS Studies Coordination Office
supported by GWT-TUD GmbH
Blasewitzer Str. 43
01307 Dresden - Germany
Phone +49 351 259 33100
Fax +49 351 259 33111
E-mail: [email protected]
www.emsco.eu
With the unrestricted support of:
Florence
September 29-30, 2016
Aula Magna, University of Florence
29th September 2016
30th September 2016
14.30 OPENING CEREMONY
General Introduction
P. Fenaux, U. Platzbecker, V. Santini
Session 1: Greetings by Rector Magnificus of the University of Florence
Prof. L. Dei
Session 1: EMSCO TRIAL UPDATE
Chairs: P. Fenaux, V. Santini
14.35 DACOTA trial – status update F. Chermat, D. Gioia, S. Gloaguen
14.50 EUROPE trial – status update F. Chermat, S. Gloaguen
15.05 SAMBA trial – status update L. Ades, U. Platzbecker
15.20 Vosaroxin trial – status update L. Ades, U. Platzbecker
CLINICAL TRIALS – EVIDENCE AND WORK IN PROGRESS
Chairs: W.K. Hofmann, N.Vey
08.45 Update on the WHO classification in MDS – impact on trial design? L. Malcovati
09.00 (Genetic) markers for response and outcome to treatment with HMAs A.B. Valencia
09.15(Genetic) markers for response and outcome to treatment with ESA S. Park
09.30(Genetic) markers for response and outcome to HSCT M.G. Della Porta
09.45 Comparison of TPO-agonists in MDS E. Oliva
10.00 Secondary MDS: biology and therapeutic options M.T. Voso
10.15 Response to EPO E. Balleari
Session 2a: CLINICAL TRIALS IN THE EU – OVERVIEW – PART 1
10.30 Coffee break
15.45 Italy V. Santini
Session 2: Chairs: A. Levis, A.A. van de Loosdrecht, G. Sanz
16.00 France P. Fenaux
16.15 Germany A. Giagounidis
16.30 Coffee break
Session 2b: CLINICAL TRIALS IN THE EU – OVERVIEW – PART 2
Chairs: L. Ades, U. Germing
16.50 Spain G. Sanz
17.05 Netherlands A.A. van de Loosdrecht
17.20 Czech Republic A. Jonasova
17.35 Switzerland N. Bonadies
17.50 Great Britain D. Culligan
18.05 Update on the revision of IWG response criteria L. Ades, P. Fenaux, A. Giagounidis, A. van de Loosdrecht, U. Platzbecker, V. Santini
18.15 Closing Remarks
20.00 Dinner
TRANSLATIONAL STUDIES IN MDS POTENTIAL NEW TARGETS?
Chairs: M. Cazzola, O. Hermine
10.50 How to target innate immunity in MDS? A. Kulasekararaj
11.05 The target of lenalidomide in MDS K. Götze
11.20 How to target inflammation in MDS R. Schneider-Kramann
11.35 Iron overload and vascular damage in mice (and men?) F. Vinchi
11.50 Results of Biofer study D. Cilloni
12.05 Roundtable discussion (all)
12.30 Lunch break
Session 3: TRANSLATIONAL STUDIES IN MDS BIOLOGY AND TARGETS
Chairs: M. Fontenay, D. Haase
13.30 Update on MDS mouse models H. Medyouf
13.45 Novel targets in MDS N. Vey
14.00 Pathophysiologic commonalities of thalassemia and RS-MDS O. Hermine
14.15 Insights into biology and prognosis of CMML E. Solary
14.30 Proposal for improved diagnosis and classification of CMML F. Onida
14.45 Roundtable discussion (all)
15.30 Adjourn