neoadjuvant treatments in surgical oncology

Transcript

neoadjuvant treatments in surgical oncology
2
nd
International Conference
of Surgical Oncology
SOCIETÀ ITALIANA DI CHIRURGIA ONCOLOGICA
Italian Society of Surgical Oncology, ESSO affiliated
PERUGIA | OCTOBER 23 •24 •25 | 2016
NEOADJUVANT
TREATMENTS IN
SURGICAL ONCOLOGY
Honorary President Giuseppe Noya Congress President Prof. Annibale Donini
CONGRESS VENUE HOTEL GIO’
1
Una vita senza ricerca non è degna di essere vissuta
Platone
EXECUTIVE BOARD S.I.C.O.
President
Paolo Delrio
Past President
Achille Lucio Gaspari
Next President
Domenico D’Ugo
Secretary - Treasurer
Massimo Dessena
General Secretary
Franco Roviello
CONGRESS BOARD S.I.C.O.
Honorary President
Giuseppe Noya
Chairmen of the Board
Annibale Donini
General Surgery Emergency
University of Perugia
Tel-Fax: 39-075-5786445
e-mail: [email protected]
2
Scientific Committee
Domenico D’Ugo
Paolo Delrio
Massimo Dessena
Annibale Donini
Achille Lucio Gaspari
Luigina Graziosi
Franco Roviello
Board Members
Davide Cavaliere
Alessandro Gronchi
Daniele Marrelli
Andrea Muratore
Andrea Percivale
Young Coordinator
Raffaele De Luca
Young Coordinator
Raffaele De Luca
SYNOPTIC TABLE
Sunday, October 23th 2016
INAUGURAL CEREMONY
Palazzo Bernabei - Assisi
h. 18.00
Monday, October 24th 2016
TOWN HALL
TRUMPET HALL 1
TRUMPET HALL 2
08.30 -10.30 SIEWERT II/III ADENOCARCINOMA NEOADJUVANT THERAPY IN
OF THE ECG: OPEN PROBLEMS
BREAST CANCER
CHALLENGING SCENARIOS IN COLORECTAL LIVER METASTASIS
10.30 - 12.30 NEOADJUVANT CHEMOTHERAPY NEOADJUVANT THERAPY OF
(NAC) IN GASTRIC CANCER
CUTANEOUS MELANOMA
VIDEO SESSION- LIVER SURGERY
13.00 - 14.00 AWARDS CEREMONY
LUANA RICCA
LUNCHTIME LECTURES
14.30 - 16.30 GASTRIC CANCER PERITONEAL
CARCINOMATOSIS: HOW DO WE
TREAT IT?
ERAS IN GASTRONINTESTINAL
CANCER
OSNA SESSION
16.30 - 18.30 MINIINVASIVE SURGERY IN
GASTRIC CANCER’S TREATMENT
MEDULLARY THYROID CARCINOMA:
UP DATE ON DIAGNOSTIC AND
MULTIDISCIPLINARY TREATMENT
YOUNG SICO
Tuesday, October 25th 2016
TOWN HALL
TRUMPET HALL 1
08.30 - 10.30 RECTAL CANCER:
NEOADJUVANT STRATEGIES IN
SOFT TISSUE SARCOMA AND
GIST
NEOADJUVANT
PREVENTION
OF
SURGICAL
SITE
YOUNG SICO
10.30 - 12.30
INFECTION
13.00 - 14.00 AWARDS CEREMONY
TRUMPET HALL 2
NEOADJUVANT THERAPY
IN PANCREATIC ADENOCARCINOMA
SESSION 2 VIDEO
FONDAZIONE GUIDO BERLUCCHI
LUNCHTIME LECTURES
14.30 – 16.30 COLON CANCER PERITONEAL
CARCINOMATOSIS: CLINICAL
EVIDENCES
Selected communications:
UPPER GI
Selected Communications:
COLORECTAL CANCER AND
PERITONEAL CARCINOMATOSIS
16.30 – 18.30 MINIINVASIVE SURGERY IN THE
TREATMENT OF COLON CANCER
The detailed scientific programme will be available on the site http://www.sicoonline.org/sico_2016/
INAUGURAL CEREMONY
Sunday, October 23RD 20016
h. 18.00
Palazzo Bernabei - Assisi
4
SCIENTIFIC PROGRAMME
Monday, October 24th 2016
PLENARY ROOM
TOWN HALL
8,30-10,30: SIEWERT II/III ADENOCARCINOMA OF THE ECG:
OPEN PROBLEMS
Chairmen: G. De Manzoni (VR), C. Pinto (RE)
8,30
8th AJCC-UICCTNM Classification: nodal Involvement and Choice of
Lymphadenectomy
S. Giacopuzzi (VR)
8,45
Siewert II: Type of Resection: Total Gastrectomy or Subtotal
Esophagectomy
R. Rosati (MI)
9,00
Neoadjuvant Treatment: Chemoradiotherapy? Chemotherapy?
9,15
Molecular biomarkers of response to neoadjuvant treatments in EGJ
adenocarcinoma
D. Melisi ( VR)
9,30
Stage IV without peritoenal carcinomatosis: is there space for Conversion Surgery?
Giovanni Pallabazzer (PI)
9,45-10,052 Selected Communications
10,05-10,30 Discussion
Discussants: L. Bonavina (MI), M. Camandona (TO), A. Ruol (PD)
10,30-12,30
NEOADJUVANT CHEMOTHERAPY (NAC) IN GASTRIC CANCER
Chairmen: E. Orsenigo(MI), F. Roviello (SI)
5
10, 30 Evidences and controversies from Literature
M. De Giuli (TO)
10,45 NAC in gastric cancer: Who may benefit
S. Rausei (VA)
11,00 NAC in gastric cancer: preoperative or perioperative?
P. Morgagni (FO)
11,15 Different CHT protocols in NAC for GC
C. Milandri (E mpoli)
11,30 Surgical implications after NAC
D. Marrelli (SI)
11,45-12,05 2 Selected Communications
12,05-12,30 Discussion
Discussants: R. Palaia (NA), V. Panebianco ( Taormina), R. Persiani ( RM)
AWARDS CEREMONY
LUANA RICCA
LUNCHTIME LECTURES:
13.00-13.30 Surgery in liver colonrectal’s metastases
Prof. D. Azoulay ( Creteil-Paris)
13,30-14,00 Peritoenal Carcinomatosis’ molecular pathogenetic mechanism
Prof. Y. Yonemura ( Osaka, Japan)
6
14,30-16,30
GASTRIC CANCER PERITONEAL CARCINOMATOSIS: HOW DO WE
TREAT IT?
Chairmen: V. De Angelis (PG) , A. Garofalo ( RM)
14,30 Adjuvant HIPEC in Locally AGC
:L. Ansaloni ( BG)
14,45 GASTRICHIP: preliminary results
O. Glehen (Lyon-France)
15.00 Therapeutic HIPEC
F. Roviello (SI): Surgical point of view
M. Scartozzi (Ca): Oncoligist point of view
15.20 Intraperitoneal Chemotherapy (NIPS)
Y. Yonemura ( Osaka, Japan)
15. 35 Extensive Lavage
L. Graziosi ( PG)
15,45-16,05 2 Selected Communications
16,05- 16,30 Discussion
Discussants: A. Macrì (ME), S. Scaringi (FI), M. Valle ( RM)
16,30-18,30: MINIINVASIVE SURGERY IN GASTRIC CANCER’S TREATMENT
Chairmen: D. D’Ugo (RM), G. Tiberio (BS)
16,30 Laparoscopic total gastrectomy’s surgical technique
:A. Biondi (RM)
16,50 Laparoscopic subtotal gastrectomy’s surgical technique
:G. Sgroi (Treviglio)
17,10 Laparoscopic D2 Lymphoadenectomy in gastric cancer surgery
:E. Cocozza ( VA)
17,30 Robotic approach in gastric cancer surgery
:A. Coratti (FI)
17,30-18.00 2 Selected Communications
18.00- 18,30 Discussion
Discussants: C. Boselli ( PG), M. Cesari ( Città di Castello), M. Scatizzi (Prato)
7
Monday, October 24th 2016
Trumpet HALL 1
8,30-10,30
NEOADJUVANT THERAPY IN BREAST CANCER
Chairmen: P. Carcoforo (FE), A. Fabi(RM), R. Murgo (San Giovanni Rotondo)
8,30
Italian Survey
M. Dessena (CA)
8,45
Dedicated Diagnostic Therapeutic Care Pathways:
M. Taffurelli (BO)
9,00
The future of therapy for HER2+ patients
A. Fabi (RM)
9,15
Axillary Conserving Surgery :
V. Galimberti (MI)
9,30
Mastectomy after NAC: M.C. Cucchi (BO)
9,45
Radiotherapy G.B. Ivaldi (PV)
10,00-10,152 Selected Communications
10,15-10,30 Discussion
Discussants: R. Bussone ( TO), D. Palli (Pr), P. Perri (RM), E. Procaccini ( NA)
10,30-12,30
NEOADJUVANT THERAPY OF CUTANEOUS MELANOMA
8
Chairmen: A. Testori (IEO, MI), A.P. Ascierto (NA)
10,30 Neoadjuvant target therapy in advanced melanoma treatment
P. Queirolo (GE)
10,45 Neoadjuvant target therapy in advanced melanoma treatment
:C. Caracò (NA)
11,00 Neoadjuvant immunotheraphy with check point inhibitors in advanced
melanoma
:V. Russo (MI)
11,15 Neoadjuvant immunotheraphy with check point inhibitors in advanced
melanoma
:S. Mocellin (PD)
11,30
Isolated limbs perfusion: could it be considered as a neoadjuvant
therapy? Our experience and results.
F. Papadia (GE)
11,45-12,05 2 Selected Communications
12,05-12,30 Discussion
Discussants: P. Covarelli (PG), M. Guida (BA), C. Rossi (PD), N. Solari (GE), A.
Sommariva (PD)
LUNCHTIME
14,30-16,30: ERAS IN GASTRONINTESTINAL CANCER
Chairmen: U. Fumagalli (MI), A. Brescia ( RM)
14,30 ERAS in Gastric Cancer
S. De Pascale (MI)
14,45 Eras in aesophageal cancer
R. Rosati – (MI)
15,15 Eras in colonrectal cancer
M. Gasparrini (RM)
15, 30 Anesthesiologist’s perspectives
L. Beretta (MI)
15,45-16,05 2 Selected communications
16,05- 16,30 Discussion
Discussants: A. Contine ( Città di Castello), S. Emerenziani (Campus Biomedico-RM),M.T. Paganelli (PG)
9
16,30-18,30: OSNA SESSION
Chairmen: S. Fiorucci (PG), P. Giovenali (PG), A.Rulli (PG), A.Sidoni (PG)
Monday, October 24th 2016
Trumpet HALL 2
8,30-10,30: CHALLENGING SCENARIOS IN COLORECTAL LIVER METASTASIS
Chairmen: C. Garufi (PS) R.Pellicci (SV)
8,30
CCR with liver only metastasis: what is the optimal neoadjuvant regimen ?
:A.Sobrero (GE)
8,45
How to increase resectability of colorectal liver metastasis ?
A.Ferrero (TO)
9,00
What is the impact of pre operative chemotherapy on resectability ?
F. Giuliante(RM)
9,15
How to manage the “Vanishing Lesions”
L. Aldrighetti (MI)
9,30
Impact of HAI on chemotherapy regimen in the treatment of colorectal
liver metastasis
M. Massani (TV)
9,45-10,052 Selected Communications
10,05-10,30 Discussion
Discussants: G. Ercolani (BO), G. Griseri (SV), F. Leone (TO) A. Percivale (SV)
10,30-12,30
10
VIDEO SESSION- LIVER SURGERY
Chairmen: D. Azoulay ( Creteil, Paris), A. Risaliti (UD)
10,30-10,50 Complex lap liver resections for colorectal mets: pushing the
limits” Equipe “Aldrighetti”
10,50-11,10 Laparoscopic two-stage hepatectomy for multiple bilateral colorectal metastases.
Roberto Lo Tesoriere (Equipe “Ferrero)
11,10-11,30 Two stage hepatectomy with occlusion of left portal vein and of
right anterior portal vein
Equipe “Giuliante”
11,30-11,50 Video Gruppo Risaliti (Udine)
11,50-12,10 Video Filauro (Genova)
Discussants: R. Cirocchi (TR) , A. Patriti (PG), E. Cavazzoni (PG)
LUNCHTIME
14,30-16,30: MEDULLARY THYROID CARCINOMA: UP DATE ON DIAGNOSTIC AND MULTIDISCIPLINARY TREATMENT
Chairmen: A.Pontecorvi (RM), M.Testini (BA)
14,30 Update on diagnosis of medullary thyroid carcinoma
C. Fanelli (PG)
14,45 Genetic of medullary thyroid carcinoma
Daniela Pasquali (NA)
15,15 Medullary thyroid carcinoma: Prophylactic treatment: When and how
Celestino Pio Lombardi (RM)
15, 30 Surgical treatment of medullary thyroid carcinoma: What Lymphectomy?
Nicola Avenia (TR)
15,45-16,05 The role of new drugs in medical treatment of medullary thyroid carcinoma
Efisio Puxeddu (PG)
16,05- 16,30 Selected Communications
Discussants: Pietro Giorgio Calò (Ca), Giovanni Conzo (NA), Paolo Del Rio (Pr),
Salvatore Sorrenti,(RM) Alessandro Sanguinetti (TR) Andrea Polistena
(PG), Massimo Monacelli (PG), Michele D’Ajello (TR), Roberta Lucchini
(TR)
16,30-18,30: YOUNG SICO
11
Tuesday, October 25th 2016
Trumpet HALL 1
8,30-10,30
NEOADJUVANT STRATEGIES IN SOFT TISSUE SARCOMA AND GIST
Chairmen: V. Quagliuolo (MI), F. Roila (TR)
8,30
Is there any standard approach to neoadjuvant chemotherapy in STS?
G. Grignani, IRCC Candiolo
8,45
Decision making and management of preoperative treatments for rare
tumors within a national collaborative network.
M. Fiore (MI)
9,00 Neoadjuvant radiation therapy in STS: when is needed, when is
not.
A. De Paoli (Aviano)
9,15
Neoadjuvant TKIs in GIST: evolving indications .
D. Cavaliere (FO)
9,30 9,45-10,052 Selected Communications
10,05-10,30 Discussion
Discussants: F.De Cian(GE), A. Oddi, (RM) E. Pennacchioli, (IEO MI ), S. Sandrucci (TO)
10,30-12,30: YOUNG SICO
12
LUNCHTIME
14, 30 - 16,30 SELECTED COMMUNICATIONS: UPPER GI
Chairmen: A. Liboni (FE), C. Zingaretti ( PU)
Discussants: V. BRESADOLA, P. Castagnoli ( Spoleto), E. Minciotti ( Branca),
G. Mura (AR), M. SIMONE (BA)
Tuesday, October 25th 2016
Trumpet HALL 2
8,30-10,30:NEOADJUVANT THERAPY IN PANCREATIC ADENOCARCINOMA
Chairmen: G. Balzano( MI) E. Corgna (PG)
Discussants: G Malleo (Verona)– S. Alfieri (Roma)
8.30
Clinical cases: surgery first or neadjuvant treatment?
Clinical Case 1 Giovanni Capretti (Rozzano)
Clinical Case 2 Gian Luca Baiocchi (Brescia)
9.00 Role of neoadjuvant treatment in resectable and borderline pancreatic cancer: evidences and guidelines
Massimo Falconi (Milano)
9.15
Which neoadjuvant treatment in pancreatic cancer? The oncologist’s doubts
Nicola Silvestris (Bari)
9.30
Criteria to select patients for surgery after neoadjuvant treatment
Riccardo Casadei (Bologna)
9.40
Do we do the same? Present practice and results of surgery after
neoadjuvant treatment in two high-volume centers
R. Salvia (Verona)
U. Boggi (Pisa)
10.25
ABSTRACT SESSION (2 abstracts)
Chairmen: R. Girelli (cdc Pederzoli, Peschiera) – S. Alfieri (Pol.
Gemelli, Roma)
SESSION 2: VIDEO (11-12.30)
Chairmen: A. Zerbi (Ist. Clinico Humanitas Rozzano); P Baccari (Perugia)
Discussants: R. Girelli (cdc Pederzoli, Peschiera) Di Sebastiano P. (Chieti), P
Ubiali (Pordenone)
13
12345-
LUNCHTIME
14, 30 - 16,30
Selected Communications:
COLORECTAL CANCER AND PERITONEAL CARCINOMATOSIS
Chairmen: S. Bonilauri (RE), A.L. Gaspari (RM), S. Scabini (GE)
Discussants: G.L. BAIOCCHI (BS) G. Garulli (Riccione), M. Martinotti (CR), A.
Parisi (TR)
14
TUESDAY, October 25th 2016
PLENARY ROOM
TOWN HALL
8,30-10,30: RECTAL CANCER: NEOADJUVANT
Chairmen: D. Nitti (PD), V. Valentini (RM), P. Marini (RM)
8,30
Is neoadjuvant therapy always required for clinicall stages II-III rectal
cancer?
P. Delrio (NA)
8,45
Management of asymptomatic stage IV rectal cancer
S. Cascinu (MO)
9,00
Rectum Sparing approaches after neoadjuvant therapy
C. Coco (RM)
9,15
Transanal TME after neoadjuvant therapy
Muratore (TO)
9,30
RESARCH Study
S. Pucciarelli (PD)
9,45-10,052 Selected Communications
10,05-10,30 Discussion
Discussants: C. Aristei (PG), C. Belluco (Aviano)A. De Paoli (Aviano), S. Lonardi
(PD), F. PRETE (BA), G. Romano (NA)
11,00-12,30 PREVENTION OF SURGICAL SITE INFECTION
Chairmen: M Lucchese (FI), D. Pacchiarini (PG), G. Cavallesco (FR)
11.00-11.20 Hospital related infections: epidemiology and economic impact.
M. Moro (MI)
11.20- 11-40 Surgical theater’s infective risk and safety: oncological patients
management and treatment.
11.40-12.00 Infection prevention in an oncological patient.
12.00-12.20 Bundle of care: clinical evidence evaluation
F. Di Marzo
15
AWARDS CEREMONY
FONDAZIONE GUIDO BERLUCCHI
LUNCHTIME LECTURES:
13.00-13.30 Prof. C. Wittekind (University of Leipzig- Germany)
Principles Of Tnm Staging After Neo-Adjuvant Treatments
13,30-14,00 Prof. O. Glehen (Lyon- France)
Colorectal Carcinomatosis: Cytoreductive Surgery and HIPEC as a standard of treatment
14,30-16,30: COLON CANCER PERITONEAL CARCINOMATOSIS: CLINICAL EVIDENCES
16
Chairmen: L. Crinò (PG), O. Glehen (Lyon-France), M. Vaira (Candiolo-TO)
14,30Adjuvant HIPEC in Locally ACC
:M. Deraco (MI)
14,45 Therapeutic HIPEC
ALFREDO FALCONE (PISA)
M. Robella (TO)
15,15 Hipec in rectal cancer
C. Sassaroli (NA)
15, 30 Learning Curve and Surgical Performance of Citoreductive Surgery and
HIPEC
S. Kusamura (MI)
15,45-16,05 2 Selected Communications
16,05- 16,30 Discussion
Discussants: D. Cavaliere (Forlì) M. Framarini (Forlì), E.M. Pasqual (UD)
16,30-18,30: MINIINVASIVE SURGERY IN THE TREATMENT OF COLON
CANCER
Chairmen: F. Basile (CT), M. Basti (Pescara), G. Anania (FE)
1: R. Persiani (RM): TATME
2: G. Baldazzi (Abano Terme):Mini-invasive surgical approach in left colon
cancer
3: P. P. Bianchi (Gr): Robotic approach: evidence from literature
4: M. Guerrieri (An): Transanal Endoscopic Microsurgery
5: G. Navarra G. (Me): Technological Innovations in right colon cancer surgical
approach
6: M. Pavanello (Asolo): Transverse colectomy:mini-invasive surgical approach
Discussants : G. Antonini (Castiglion del Lago), F. Breccolotto (PG), N. Gullà
(Me), Rondelli F. (PG)
17
GENERAL INFORMATION
CONFERENCE VENUE
Hotel Giò Wine e Jazz Area a Perugia
Via R. D’Andreotto, 19
06124 Perugia (PG)
Tel. 39 075 5731100
[email protected]
The Hotel is in the city centre of Perugia, 1 km far away from the railway
station, and 200 mt from the minimetrò station. You reach the historic centre in 5 minutes by minimetrò. From Hotel Giò you can reach the historic
centre in 5 minutes by car or in 20 minutes on foot.
SICO SECRETARIAT and ORGANIZING SECRETARIAT - Two distinct secretariats will be at the disposal of the conference participants.
The Organizing Secretariat will be at the disposal of the conference participants at Giò Hotel starting from 10.00 a.m. of 23 October 2016 and over the following days until the end of the conference.
The SICO Secretariat is at the disposal of MEMBERS to answer any enquiry for societal information, to check and settle their membership fee; it
will also be available to accept new memberships.
18
Registration with the 2nd International Conference of
Surgical Oncology is mandatory and will entitle to:
attend the scientific sessions of 23/24/25 October, receive a conference
set, light lunch and coffee breaks as planned, attendance certificate
Membership fees, including 22% VAT OVER-40 SICO MEMBERS (up to date with the payment of the 2016
membership fee € 100.00) *
Free of charge
UNDER-40 SICO SPECIALIZING MEMBERS (up to
date with the payment of the 2016 membership fee € 50.00)
*
Free of charge
GIRCS MEMBERS (up to date with the payment of the 2016 membership fee)
Free of charge
NON-SICO MEMBERS
€ 250.00
Specializing medicine doctor **
Free of
charge
Medicine Student***
Free of
charge
NOTES:
*The 2nd International Conference of Surgical Oncology is free of
charge for SICO MEMBERS up to date with the payment of the 2016
membership fee. However, they will still have to send the Conference
registration form to register. To become members please visit the website
www.sicoonline.org.
** Specializing medicine doctors whose work will be selected for submission at the plenary session are required to become members (€ 50.00);
***Please send the certificate of enrolment with your University Course
CANCELLATION POLICY: The membership fee may only be reimbursed if cancellation is notified to the Organizing Secretariat not later
than 15 JULY 2016.
PRESENTERS
At least two of the Presenters of the selected communications (as either
oral presentations or posters) should be members of the Italian Society of
Oncological Surgery and up to date with the payment of the 2016 membership fee.
SCIENTIFIC INFORMATION
The Congress will include parallel sessions.
SHOWINGS
19
Only the showing of Personal Computer images is accepted: traditional slide
projectors will not be installed and the use of personal PCs is not allowed. The
rooms are equipped with a video-projector connected to a Personal Computer for
the presentation of the works. The relevant files shall be prepared on Power Point
2000 and delivered at least 2 hours before the beginning of the session on a pen
drive to the computer centre.
The computer centre will be network connected to the conference rooms: all the
screenings will be automatically forwarded to the right room.
GUIDELINES FOR CHAIRMEN AND SPEAKERS
Chairmen shall:
- be in the room at least 10 minutes before the beginning of the session;
- make sure that the session and the presentations remain within the allotted times;
Speakers shall:
- identify the room where the session is held in due time;
- hand in the visuals of their presentation, if possible, at least 2 hours before the
beginning of the session to the computer centre
- be in the room at least 10 minutes before the beginning of the session.
CME CREDITS
20
The event of 24/25 October will receive single accreditation from the Ministry
of Health for the following professions:
Medicine Doctors-Surgeons reference subjects: general surgery; gastroenterology; internal medicine; oncology; radiotherapy; obstetrics and gynaecology; radiodiagnostics; nurses and Biologists.
An attendance sheet will be signed when entering and leaving the room and credits will only be certified if the attendance time will be the actual set time for the
event and if the final test to check the learning level will be passed.
The CME credit certification will be sent by e-mail after completing the set procedures.
The CME Provider is Kassiopea Group, recognized by AGENAS under number
305. Attendance certificates
At the end of the Conference all duly registered attendants will receive an attendance certificate. Certificates will only be given at the end of the sessions,
also in case of late closing
Badges
Admission to the conference venue, the exhibition area and the scientific sessions will only be possible if in possession of the bar-code badge given by the
Organizing Secretariat at the time of registration.
The badge is a personal document and shall be shown to the controlling staff. It
is the only valid document to collect the attendance certificate and the only way
to receive credits.
Amendments
The Scientific Secretariat and the Organizing Secretariat reserve the right to
make all the necessary amendments to the programme which are deemed necessary for technical and/or scientific reasons.
21
SOCIETÀ ITALIANA DI CHIRURGIA ONCOLOGICA
Italian Society of Surgical Oncology, ESSO affiliated
ORGANIZING SECRETARIAT and NATIONAL SECRETARIAT SICO
22
Via Stamira 10
09123 Cagliari
Tel. 070651242 Fax 070656263
[email protected]
www.sicoonline.org
www.kassiopeagroup.com