CURRICULUM VITAE INFORMAZIONI PERSONALI Nome Gandolfo

CURRICULUM VITAE
INFORMAZIONI PERSONALI
Nome
Gandolfo Maria Teresa
Data di nascita
25 giugno 1975
Qualifica
Medico chirurgo- specialista in Nefrologia- MD PhD
Amministrazione
Incarico attuale
Dirigente Medico U.O. Nefrologia
Numero telefonico dell'ufficio
02/55034553
Fax dell'ufficio
02/55034550
E-mail istituzionale
TITOLI DI STUDIO E
PROFESSIONALI ED
ESPERIENZE LAVORATIVE
Titolo di studio
Altri titoli di studio e professionali
Esperienze professionali (incarichi
ricoperti)
Laurea in Medicina e Chirurgia presso Università di Genova
(28/7/2000)
- Specializzazione in Nefrologia presso Università di Genova
(26/10/2005)
- Acquisizione del titolo di Dottore di Ricerca al termine del Dottorato in
“Biologia e fisiopatologia cardiaca, vascolare, renale e metabolica”,
appartenente alla Scuola di Dottorato in “Scienze e Tecnologie
biomediche”, presso la Facoltà di Medicina e Chirurgia, Università di
Genova (1/1/2006 --> 31/12/2008).
Durante il Dottorato di Ricerca, la dott.ssa ha svolto fellowship di
ricerca presso Johns Hopkins University, Baltimore, MD, USA nel
Dipartimento di Patologia (Sezione Patologia Renale) e Medicina,
Nefrologia
Capacità linguistiche
Giugno 1990: First Certificate in English, rilasciato dall’Università di
Cambridge.
Ottima conoscenza della lingua inglese scritta e parlata.
Capacità nell'uso delle tecnologie
Buona
Altro (partecipazione a convegni e
seminari, pubblicazioni,
collaborazioni a riviste; ecc., ed
ogni altra informazione che il
dirigente ritiene di dover
pubblicare)
Articoli pubblicati:
1. Verzola D, Villaggio B, Berruti V, Gandolfo MT, Deferrari G,
Garibotto G. Apoptosis induced by serum withdrawal in human
mesangial cells. Role of IGFBP-3. Exp Nephrol. 2001;9:366-71.
2. Verzola D, Bertolotto MB, Villaggio B, Ottonello L, Dallegri F,
Frumento G, Berruti V, Gandolfo MT, Garibotto G, Deferran G.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Taurine prevents apoptosis induced by high ambient glucose in
human tubule renal cells. J Investig Med. 2002 Nov;50(6):443-51.
Garibotto G, Sofia A, Saffioti S, Russo R, Deferrari G, Rossi D,
Verzola D, Gandolfo MT, Sala MR. Interorgan exchange of
aminothiols in humans. Am J Physiol Endocrinol Metab.
2003;284:757-63
Verzola D, Bertolotto MB, Villaggio B, Ottonello L, Dallegri F,
Salvatore F, Berruti V, Gandolfo MT, Garibotto G, Deferrari G.
Oxidative stress mediates apoptotic changes induced by
hyperglycemia in human tubular kidney cells. J Am Soc Nephrol.
2004;15 Suppl 1:S85-7.
Gandolfo MT, Verzola D, Salvatore F, Gianiorio G, Procopio V,
Romagnoli A, Giannoni M, Garibotto G. Gender and the
progression of chronic renal diseases: does apoptosis make the
difference? Minerva Urol Nefrol. 2004;56:1-14.
Verzola D, Gandolfo MT, Salvatore F, Villaggio B, Gianiorio F,
Traverso P, Deferrari G, Garibotto G. Testosterone promotes
apoptotic damage in human renal tubular cells. Kidney Int.
2004;65:1252-61.
Garibotto G, Sofia A, Procopio V, Villaggio B, Tarroni A, Di Martino
M, Cappelli V, Gandolfo MT, Aloisi F, De Cian F, Sala MR,
Verzola D. Peripheral tissue release of interleukin-6 in patients
with chronic kidney diseases: Effects of end-stage renal disease
and microinflammatory state. Kidney Int. 2006;70:384-90.
Garibotto G, Sofia A, Balbi M, Procopio V, Villaggio B, Tarroni A,
Di Martino M, Cappelli V, Gandolfo MT, Valli A, Verzola D. Kidney
and splanchnic handling of interleukin-6 in humans. Cytokine.
2007 Jan;37(1): 51-4.
Gandolfo MT, Rabb H. Impact of ischemia times on kidney
transplant outcomes. Transplantation 2007; 83(3): 254.
Gandolfo MT, Rabb H. Very early alloantigen-independent
trafficking of lymphocytes during ischemic acute kidney injury.
Kidney Int. 2007 Jun; 71(12):1193-5.
Verzola D, Gandolfo MT, Ferrario F, Rastaldi MP, Villaggio B,
Gianiorio F, Giannoni M, Rimoldi L, Lauria F, Miji M, Deferrari G,
Garibotto G. Apoptosis in the kidneys of patients with type II
diabetic nephropathy. Kidney Int. 2007 Nov; 72(10): 1262-72.
Garibotto G, Russo R, Sofia A, Ferone D, Fiorini F, Cappelli V,
Tarroni A, Gandolfo MT, Vigo E, Valli A, Arvigo M, Verzola D,
Ravera G, Minuto F. Effects of uremia and inflammation on growth
hormone resistance in patients with chronic kidney diseases.
Kidney Int. 2008 Oct;74(7):937-45. Epub 2008 Jul 16.
Verzola D, Gandolfo MT, Gaetani G, Ferraris A, Mangerini R,
Ferrario F, Villaggio B, Gianiorio F, Tosetti F, Weiss U, Traverso
P, Mji M, Deferrari G, Garibotto G. Accelerated senescence in the
kidneys of patients with type 2 diabetic nephropathy. Am J Physiol
Renal Physiol. 2008 Nov;295(5):F1563-73. Epub 2008 Sep.
Garibotto G, Verzola D, Sofia A, Saffioti S, Menesi F, Vigo E,
Tarroni A, Deferrari G, Gandolfo MT. Mechanisms of renal
ammonia production and protein turnover. Metab Brain Dis. 2009
Mar;24(1):159-67. Epub 2008 Dec 13.
Bagnasco SM, Mohammed BS, Mani H, Gandolfo MT, Haas M,
Racusen LC, Montgomery RA, Kraus E. Oxalate deposits in
biopsies from native and transplanted kidneys, and impact on graft
function. Nephrol Dial Transplant. 2009 Apr;24(4):1319-25. Epub
2008 Dec 22.
Liu M, Chien C, Grigoryev DN, Gandolfo MT, Colvin RB, Rabb H.
Effect of T cells on vascular permeability in early ischemic acute
kidney injury in mice. Microvasc Res. 2009 May;77(3):340-7. Epub
2009 Feb 7.
Satpute SR, Park JM, Jang HR, Agreda P, Liu M, Gandolfo MT,
Racusen L, Rabb H. The role for T cell repertoire/antigen-specific
interactions in experimental kidney ischemia reperfusion injury. J
Immunol. 2009 Jul 15;183(2):984-92. Epub 2009 Jun 26.
18. Verzola D, Villaggio B, Procopio V, Gandolfo MT, Gianiorio F,
Famà A, Tosetti F, Traverso P, Deferrari G, Garibotto G.
Androgen-mediated apoptosis of kidney tubule cells: Role of c-Jun
amino terminal kinase. Biochem Biophys Res Commun. 2009 Jul
16. [Epub ahead of print]
19. Gandolfo MT, Jang HR, Bagnasco SM, Ko GJ, Agreda P, Satpute
SR, Crow MT, King LS, Rabb H. Foxp3(+) regulatory T cells
participate in repair of ischemic acute kidney injury. Kidney Int.
2009 Jul 22. [Epub ahead of print]
20. Jang HR, Gandolfo MT, Ko GJ, Satpute SR, Racusen L and Rabb
H. Early exposure to germs modifies kidney damage and
inflammation after experimental ischemia-reperfusion injury.
Accettato in AJP in data 7/8/2009.
Capitoli di libri:
Gandolfo MT
&
Rabb
H.
Ischemia-Reperfusion
Injury:
Pathophysiology and Clinical Approach. In: Chronic Allograft Failure:
Natural History, Pathogenesis, Diagnosis and Management. Edito da
Nasimul Ahsan. Landes Biosciences 2008.
Abstracts:
1. Garibotto G, Barreca A, Sofia A, Dertenois L, Pastorino N, Saffioti
S, Timossi G, Fiorini F, Gandolfo MT, Verzola D, Deferrari G,
Russo R: Muscle protein synthesis is decreased, and correlates
with the increase in blood of insulin-like growth factor binding
protein-1 (IGFBP-1) in hemodialysis (HD) patients with proteinenergy malnutrition (PEM). ASN/ISN Congresso Mondiale di
Nefrologia, S. Francisco, USA, 10-14 Ottobre 2001. J Am Soc
Nephrol vol 12, A0380, 72A, Sept 2001.
2. Verzola D, Gandolfo MT, Villaggio B, Rossi D, Salvatore F,
Berruti V, Garibotto G, Deferrari G. Androgens increase
cyclosporine-induced apoptosis in human tubular cells
39th
Congresso ERA-EDTA, Copenhagen, Danimarca, 14-17 Luglio
2002. NDT vol 17, S12, p.167, M432, July 2002.
3. Verzola D, Gandolfo MT, Salvatore F, Villaggio B, Gianiorio F,
Deferrari G, Garibotto G: Androgens promote apoptotic processes
in human renal tubular cells. Congresso mondiale di Nefrologia,
Dialisi e Trapianto, Berlino, Germania, 8-12 Giugno 2003. Abstract
book: NDT vol 18, S4, T86, 2003.
4. Verzola D, Gandolfo MT, Villaggio B, Salvatore F, Gianiorio F,
Procopio V, Deferrari G, Garibotto G: Testosterone Promotes
Apoptosis by Stimulating a Fas/Fasl Dependent Pathway in
Human Proximal Tubular Cells. Congresso della Società
Americana di Nefrologia, San Diego, California, 12-17 Novembre
2003. J Am Soc Nephrol 14, 325A, 2003.
5. Gandolfo MT, Verzola D, Salvatore F, Procopio V, Gianiorio F,
Traverso P, Villaggio B, Deferrari G, Garibotto G: Effects of
estrogen on the apoptosis induced by testosterone in human renal
tubular cells. 41° Congresso ERA-EDTA, Lisbona, Por togallo, 1518 Maggio 2004 (Abstract premiato). Abstract Book p 14.
6. Gandolfo MT, Salvatore F, Verzola D, Procopio V, Famà A,
Timossi L, Deferrari G, Garibotto G: Effetti dell’estradiolo
sull’apoptosi indotta da androgeni in cellule tubulari umane in
coltura. 44° Congresso della Società Italiana di Ne frologia, Torino,
2004. Giornale Italiano di Nefrologia s29, ps21, 2004.
7. Gandolfo MT, Verzola D, Gianiorio F Villaggio B, Lauria F,
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
Rastaldi MP, Ferrario F, Miji M, Cavatorta F, Deferrari G, Garibotto
G: Apoptosi nella nefropatia del diabete tipo 2: rapporti con i
parametri clinici. 46° Congresso della Società Ital iana di
Nefrologia, Montesilvano (PE), 4-7 Maggio 2005. Giornale Italiano
di Nefrologia s32,s10, 5, 2005.
Gandolfo MT, Verzola D, Gianiorio F Villaggio B, Lauria F,
Rastaldi MP, Ferrario F, Miji M, Giannoni M, Deferrari G, Garibotto
G: Kidney apoptotic changes in patients with type 2 diabetic
nephropathy at different clinical stages. 18° EDNSG Meeting,
Arnhem, Olanda, 13-14 Maggio 2005.
Gandolfo MT, Verzola D, Gianiorio F, Villaggio B, Lauria F,
Rastaldi MP, Ferrario F, Miji M, Deferrari G, Garibotto G: Kidney
apoptotic changes in patients with type 2 diabetic nephropathy and
early or late clinical impairment. 42° Congresso ER A-EDTA,
Istanbul, Turchia, 4-7 Giugno 2005. Abstract book: NDT vol 20,
S5, v204, MP005, 2005.
Gandolfo MT, Verzola D, Deferrari G, Garibotto G: Apoptosi e
perdita di cellule renali nel diabete tipo 2. VII edizione Parma
Diabete, Parma,16-18 Giugno 2005.
Gandolfo MT, Verzola D, Villaggio B, Lauria F, Rastaldi MP,
Ferrario F, Miji M, Deferrari G, Garibotto G. Kidney Apoptotic
Changes in Patients with Type 2 Diabetes and Early or Advanced
Nephropathy. Congresso della Società Americana di Nefrologia,
San Diego, USA, 16-19 Novembre, 2006. J Am Soc Nephrol 17,
Abstract Issue, 398A.
Gandolfo MT, Ascon D, Liu M, Agreda P, Bagnasco S, Rabb H.
Dynamic and Sub-Population-Specific Lymphocyte Trafficking
during the Extension and Healing Phase of Ischemic Acute Kidney
Injury in Mice. Congresso della Società Americana di Nefrologia,
San Diego, USA, 16-19 Novembre, 2006. J Am Soc Nephrol 17,
Abstract Issue, 530A.
Maria Teresa Gandolfo, Dolores Ascon, Manchang Liu, Patricia
Agreda, Serena Bagnasco & Hamid Rabb. Dynamic and subpopulation-specific lymphocyte trafficking during the healing phase
of ischemic acute kidney injury in mice: potential role of
lymphocytes in renal repair. Kidney Development and Repair
Conference. Alexandria, VA, USA, 8-9 Febbraio 2007.
Maria Teresa Gandolfo, Dolores Ascon, Manchang Liu, Patricia
Agreda, Serena Bagnasco & Hamid Rabb. Dynamic and subpopulation-specific lymphocyte trafficking during the healing phase
of ischemic acute kidney injury in mice: potential role of
lymphocytes in renal repair. Mid-Atlantic Nephrology Young
Investigator’s Forum, Baltimora, MD, USA, 7-8 Marzo, 2007.
Gandolfo MT, Ascon D, Liu M, Agreda P, Bagnasco S, Rabb H.
Dynamic trafficking of specific lymphocyte subpopulations in the
healing phase of ischemic acute kidney injury in mice: potential
role of lymphocytes in renal repair. American Transplant
Congress, San Francisco USA, 5-9 Maggio, 2007. Am J
Transplant suppl 2, vol 7, p 320, n. 662.
Gandolfo MT, Verzola D, Ferrario F, Rastaldi MP, Villaggio B,
Gianiorio F, Lauria F, Miji M, Deferrari G, Garibotto G. Apoptosis of
glomerular and tubule cells in patients with type 2 diabetic
nephropathy is associated with different clinical predictors and
renal outcomes. 20th EDNSG Meeting, Edinburgo, Scozia, 11-12
Maggio, 2007.
Gandolfo MT, Verzola D, Ferrario F, Rastaldi MP, Villaggio B,
Gianiorio F, Lauria F, Miji M, Deferrari G, Garibotto G. Glomerular
and tubular apoptotic changes in patients with type 2 diabetic
nephropathy: correlations with different clinical predictors and
kidney outcomes. 44th ERA-EDTA Meeting, Barcellona, Spagna,
21-24 Giugno, 2007.
Gandolfo MT, Agreda P, Bagnasco S and Rabb H. Lymphocytes
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
In The Healing Phase Of Ischemic Acute Kidney Injury: Modulation
Of Tubular Structure And Lymphocyte Trafficking By
Methylprednisolone And Mycophenolate Mofetil. Congresso della
Società Americana di Nefrologia, San Francisco, USA, 31 Ottobre5 Novembre, 2007. J Am Soc Nephrol 18, Abstract Issue, 642A.
Gandolfo MT, Verzola D, Rastaldi MP, Villaggio B, Giannoni M,
Lauria F, Weiss U, Deferrari G, Garibotto G. Apoptosis of
glomerular and tubular cells in patients with type 2 diabetic
nephropathy: association with different clinical predictors and renal
outcomes. Congresso della Società Americana di Nefrologia, San
Francisco, USA, 31 Ottobre- 5 Novembre, 2007. J Am Soc
Nephrol 18, Abstract Issue, 327A-328A.
Verzola D, Procopio V, Passalacqua M, Gandolfo MT, Villaggio B,
Fama’ AM, Melloni E, Tosetti F, Deferrari G, Garibotto G. Role of
the c-jun N-Terminal Kinase (JNK) pathway in androgen-induced
apoptosis of kidney tubular cells. Congresso della Società
Americana di Nefrologia, San Francisco, USA, 31 Ottobre- 5
Novembre, 2007. J Am Soc Nephrol 18, Abstract Issue, 145A146A.
Hye Ryoun Jang, Maria Teresa Gandolfo, Shailesh Satpute,
Hamid Rabb. The role of B cells during the healing phase of
kidney ischemia-reperfusion injury. Research Retreat 2008Individualized Care in Medicine, Baltimore MD, USA, 28 april
2008.
Gandolfo MT, Agreda P, Soloski MJ, Crow MT, Bagnasco S &
Rabb H. Lymphocyte trafficking during repair from kidney
ischemia-reperfusion:
effects
of
corticosteroids
and
mycophenolate mofetil. Research Retreat 2008- Individualized
Care in Medicine, Baltimore MD, USA, 28 aprile 2008.
Gandolfo MT, Verzola D, Ferraris A, Mangerini R, Ferrario F,
Lauria F, Tosetti F, Giannoni M, Weiss U, Traverso P, Saffioti S,
Deferrari G, Garibotto G. Accelerated cell senescence in the
kidneys of patients with type 2 diabetic nephropathy. 21th EDNSG
Meeting, Hannover, Germania, 15-17 Maggio, 2008.
Gandolfo MT, Agreda P, Crow MT, Soloski MJ, Bagnasco S,
Rabb H. Lymphocyte trafficking during repair from kidney
ischemia-reperfusion:
effects
of
corticosteroids
and
mycophenolate mofetil. American Transplant Congress, Toronto,
Canada, 31 Maggio-4 giugno 2008. Am J Transplant suppl 2, vol
8, p 234, n. 210.
Jang HR, Gandolfo MT, Satpute S, Rabb H. The role of B cells
during the healing phase of kidney ischemia reperfusion injury.
American Transplant Congress, Toronto, Canada, 31 Maggio-4
giugno 2008. Am J Transplant suppl 2, vol 8, p 186, n. 28.
M. T. Gandolfo, H. R. Jang, S. Satpute, L. S. King, S. Bagnasco,
+
H. Rabb. Foxp3 Regulatory T Cells Participate in Repair from
Kidney Ischemia-Reperfusion Injury (IRI). Congresso della Società
Americana di Nefrologia, Philadelphia, USA, 4-9 Novembre, 2008.
J Am Soc Nephrol volume 19, Abstract Issue, 62A.
Shailesh R. Satpute, Hye Ryoun Jang, Patricia Agreda, Manchang
Liu, Maria-Teresa Gandolfo, Lorraine Racusen, Hamid Rabb. T
Cell-Mediated Ischemia Reperfusion Injury Requires Diverse T
Cell Receptor Repertoire. Congresso della Società Americana di
Nefrologia, Philadelphia, USA, 4-9 Novembre, 2008. J Am Soc
Nephrol volume 19, Abstract Issue, 167A.
Hye Ryoun Jang, Maria-Teresa Gandolfo, Shailesh Satpute,
Hamid Rabb. B Cells Modulate Healing after Ischemic Acute
Kidney Injury (AKI). Congresso della Società Americana di
Nefrologia, Philadelphia, USA, 4-9 Novembre, 2008. J Am Soc
Nephrol volume 19, Abstract Issue, 169A.
Hye Ryoun Jang, Maria-Teresa Gandolfo, Shailesh Satpute,
Hamid Rabb. Perinatal Exposure to Germs Influences Kidney
Response to Ischemic Acute Kidney Injury. Congresso della
Società Americana di Nefrologia, Philadelphia, USA, 4-9
Novembre, 2008. J Am Soc Nephrol volume 19, Abstract Issue,
169A.
30. M.T. Gandolfo, D. Verzola, F. Ferrario, F. Gianiorio, F. Tosetti, U.
Weiss, M. Mji, G. Deferrari, G. Garibotto. Accelerated Senescence
in the Kidneys of Patients Affected by Type 2 Diabetic
Nephropathy. Congresso della Società Americana di Nefrologia,
Philadelphia, USA, 4-9 Novembre, 2008. J Am Soc Nephrol
volume 19, Abstract Issue, 402A.
31. Serena M. Bagnasco, Maria Teresa Gandolfo, Basim
Mohammed, Haresh Mani, Mark Haas, Lorraine C. Racusen,
Robert A. Montgomery, Edward Kraus. Oxalate Deposits in Kidney
Allograft Biopsies within the First Year Post Transplant and Graft
Dysfunction. Congresso della Società Americana di Nefrologia,
Philadelphia, USA, 4-9 Novembre, 2008. J Am Soc Nephrol
volume 19, Abstract Issue, 447A.
32. M.T. Gandolfo, H.R. Jang, S. Bagnasco, P. Agreda, S. Satpute,
M. Crow, L. King and H. Rabb. Foxp3+ regulatory T cells
participate in repair from kidney ischemia-reperfusion injury.
Congresso Mondiale di Nefrologia, Milano, 22-26 Maggio 2009.
Premi:
Premio per la presentazione al 41° Congresso ERA-ED TA,
Lisbona, Portogallo - 15-18, Maggio 2004: Effects of estrogen on
the apoptosis induced by testosterone in human renal tubular
cells.