1. Carpanelli C, Gaiani G, Albini A. Alchoolysis of N,N`
Transcript
1. Carpanelli C, Gaiani G, Albini A. Alchoolysis of N,N`
Dr. Adriana Albini List of Pubblications (IF from 1991) 1. Carpanelli C, Gaiani G, Albini A. Alchoolysis of N,N'-Dyaryl–sulphur-diimides. Gazz Chim Ital. 112:409-14; 1982. 2. Parodi S, Pala M, Russo P, Zunino A, Balbi C, Albini A, Valerio F, Cimberle MR, Santi L. DNA damage in liver, kidney, bone marrow, and spleen of rats and mice treated with commercial and purified aniline as determined by alkaline elution assay and sister chromatid exchange induction. Cancer Res. 42:2277-83.; 1982. 3. Parodi S, Santi L, Russo P, Albini A, Vecchio D, Pala M, Ottaggio L, Carbone A. DNA damage induced by auramine O in liver, kidney, and bone marrow of rats and mice, and in a human cell line (alkaline elution assay and SCE induction). J Toxicol Environ Health. 9:94152.; 1982. 4. Albini A, Pontz B, Mensing H, Cantz M, Muller PK. [Chemotactic activity of fibroblasts in mucopolysaccharidoses]. Padiatr Padol. 18:263-7; 1983. 5. Albini A, Richter H, Pontz BF. Localization of the chemotactic domain in fibronectin. FEBS Lett. 156:222-6.; 1983. 6. Albini A, Muller PK, Parodi S. A method to select cell populations with enhanced chemotactic activity. Biosci Rep. 4:311-8.; 1984. 7. Allavena G, Albini A, Parodi S. Chemotactic response of SV40 virus transformed fibroblasts to conditioned medium: dependence on time and cell number. Boll Soc Ital Biol Sper. 60:236975.; 1984. 8. Mensing H, Albini A, Krieg T, Pontz BF, Muller PK. Enhanced chemotaxis of tumor-derived and virus-transformed cells to fibronectin and fibroblast-conditioned medium. Int J Cancer. 33:43-8.; 1984. 9. Pontz BF, Albini A, Mensing H, Cantz M, Muller PK. Pattern of collagen synthesis and chemotactic response of fibroblasts derived from mucopolysaccharidosis patients. Exp Cell Res. 155:457-66.; 1984. 10. Albini A, Adelmann-Grill BC. Collagenolytic cleavage products of collagen type I as chemoattractants for human dermal fibroblasts. Eur J Cell Biol. 36:104-7.; 1985. 11. Albini A, Adelmann-Grill BC, Muller PK. Fibroblast chemotaxis. Coll Relat Res. 5:283-96.; 1985. 12. Allavena G, Melchiori A, Carlone S, Parodi S, Renzo MFD, Albini A. Changeable chemotactic response of metastatic variant lines of RSV-transformed mouse fibroblasts. Cell Biol Int Rep. 10:191; 1986. 13. Albini A, Allavena G, Richter H, Pontz BF, Parodi S, Santi L. SV40 transformed fibroblasts recognize the same 140 kD fibronectin chemotactic fragment as non-transformed cells. Experientia. 41:1591-3.; 1985. 14. Albini A, Krieg T, Schmoeckel C, Weber L, Mueller P. Dermatofibrosarcoma protuberans: altered collagen metabolism in cell culture. J Invest Dermatol. 85:381-4.; 1985. 15. Schmoeckel C, Albini A, Krieg T, Stets R. The fibroblastic nature of dermatofibrosarcoma protuberans: morphological investigations in vivo and in vitro. Arch Dermatol Res. 278:138-47; 1985. 16. Albini A, Graf J, Kitten GT, Kleinman HK, Martin GR, Veillette A, Lippman ME. 17 betaestradiol regulates and v-Ha-ras transfection constitutively enhances MCF7 breast cancer cell interactions with basement membrane. Proc Natl Acad Sci U S A. 83:8182-6.; 1986. 17. Allavena G, Melchiori A, Carlone S, Parodi S, Renzo MFD, Albini A. Changeable chemotactic response of metastatic variant lines of RSV-transformed mouse fibroblasts. Cell Biol Int Rep. 10:191; 1986. 18. Melchiori A, Allavena G, Negrone R, Parodi S, Albini A. Effect of different cell detachment techniques on fibroblast chemotaxis to fibronectin and conditioned medium. Boll Soc Ital Biol Sper. 62:637-43.; 1986. 19. Albini A, Allavena G, Melchiori A, Giancotti F, Richter H, Comoglio PM, Parodi S, Martin GR, Tarone G. Chemotaxis of 3T3 and SV3T3 cells to fibronectin is mediated through the cellattachment site in fibronectin and a fibronectin cell surface receptor. J Cell Biol. 105:1867-72.; 1987. 20. Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aaronson SA, Kozlowski JM, McEwan RN. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res. 47:3239-45.; 1987. 21. Aresu O, Allavena G, Melchiori A, Parodi S, D'Amore E, Olivieri GB, Nicolo G, Schmidt J, Albini A. Chemotactic activity "in vitro" and transplantability in isogenic mice of radionuclideinduced murine osteosarcomas. Boll Soc Ital Biol Sper. 63:435-41.; 1987. 22. Melchiori A, Allavena G, Bohm J, Remy W, Schmidt J, Parodi S, Santi L, Albini A. Interferons inhibit chemotaxis of transformed cells and their invasion of a reconstituted basement membrane. Anticancer Res. 7:475-9.; 1987. 23. Albini A, Mitchell CD, Thompson EW, Seeman R, Martin GR, Wittek AE, Quinnan GV. Invasive activity and chemotactic response to growth factors by Kaposi's sarcoma cells. J Cell Biochem. 36:369-76.; 1988. 24. Albini A, Pontz B, Pulz M, Allavena G, Mensing H, Muller PK. Decline of fibroblast chemotaxis with age of donor and cell passage number. Coll Relat Res. 8:23-37.; 1988. 25. Allavena G, Melchiori A, Aresu O, Ferreri-Santi L, McEwan R, Kitten G, Parodi S, Albini A. "In vitro" models for studying the malignant phenotype: chemotaxis and chemoinvasion. Adv Exp Med Biol. 233:215-26; 1988. 26. Allavena G, Melchiori A, Carlone S, Di Renzo MF, Comoglio P, Parodi S, Santi L, Albini A. High chemotactic motility and growth in hard agar of a variant of RSV- transformed fibroblasts are lost in late passages. Tumori. 74:1-6.; 1988. 27. Thompson E, Reich R, Martin GR, Albini A. Factors regulation basement membrane invasion by tumor cells. In: Lippman ME, Dickson RB, editors. Breast Cancer: Cellular and Molecular Biology; 1988. p. 239-49. 28. Thompson EW, Reich R, Martin GR, Albini A. Factors regulating basement membrane invasion by tumor cells. Cancer Treat Res. 40:239-49; 1988. 29. Thompson EW, Reich R, Shima TB, Albini A, Graf J, Martin GR, Dickson RB, Lippman ME. Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens. Cancer Res. 48:6764-8.; 1988. 30. Albini A, Aukerman SL, Ogle RC, Noonan DM, Fridman R, Martin GR, Fidler IJ. The in vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants. Clin Exp Metastasis. 7:437-51.; 1989. 31. Inouye LN, Albini A, Chader GJ, Redmond TM, Nickerson JM. mRNA for interphotoreceptor retinoid-binding protein (IRBP): distribution and size diversity in vertebrate species. Exp Eye Res. 49:171-80.; 1989. 32. Percario M, Melchiori A, Aresu O, Ferreri-Santi L, Carlone S, Parodi S, Conio M, Munizzi F, Aste H, Albini A, et al. Growth of cells from esophageal squamous cell carcinoma biopsies in a reconstituted basement membrane. Boll Soc Ital Biol Sper. 65:775-81.; 1989. 33. Albini A, Toffenetti J, Zhu Z, Chader GJ, Noonan DM. Hypomethylation of the interphotoreceptor retinoid-binding protein (IRBP) promotor and first exon is linked to expression of the gene. Nucleic Acids Res. 18:5181-7.; 1990. 34. Colacci A, Perocco P, Vaccari M, Mazzullo M, Albini A, Parodi S, Taningher M, Grilli S. In vitro transformation of BALB/c 3T3 cells by 1,1,2,2- tetrachloroethane. Jpn J Cancer Res. 81:786-92.; 1990. 35. Melchiori A, Carlone S, Allavena G, Aresu O, Parodi S, Aaronson SA, Albini A. Invasiveness and chemotactic activity of oncogene transformed NIH/3T3 cells. Anticancer Res. 10:37-44.; 1990. 36. Albini A, Melchiori A, Santi L, Liotta LA, Brown PD, Stetler-Stevenson WG. Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst. 83:775-9.; 1991. IF=15,171 37. Aresu O, Nicolo G, Allavena G, Melchiori A, Schmidt J, Kopp JB, d'Amore E, Chader GJ, Albini A. Invasive activity, spreading on and chemotactic response to laminin are properties of high but not low metastatic mouse osteosarcoma cells. Invasion Metastasis. 11:2-13; 1991. IF=1,438 38. Ochieng J, Basolo F, Albini A, Melchiori A, Watanabe H, Elliott J, Raz A, Parodi S, Russo J. Increased invasive, chemotactic and locomotive abilities of c-Ha-ras- transformed human breast epithelial cells. Invasion Metastasis. 11:38-47; 1991. IF=1,438 39. Thompson EW, Nakamura S, Shima TB, Melchiori A, Martin GR, Salahuddin SZ, Gallo RC, Albini A. Supernatants of acquired immunodeficiency syndrome-related Kaposi's sarcoma cells induce endothelial cell chemotaxis and invasiveness. Cancer Res. 51:2670-6.; 1991. IF=7,616 40. Wittek AE, Mitchell CD, Armstrong GR, Albini A, Martin GR, Seemann R, Levenbook IS, Wierenga DE, Ridge J, Dunlap RC, Lundquist ML, Steis RG, Longo DL, Muller J, Jr GVQ. Propagation and properties of Kaposi's sarcoma-derived cell lines obtained from patients with AIDS: similarity of cultured cells to smooth muscle cells. Aids. 5:1485-93.; 1991. IF=5,835 41. Adatia R, Poggi L, Thompson EW, Gallo RC, Fassina GF, Albini A. Assessment of angiogenic potential– The use of AIDS–KS cell supernatants as an in vitro model. In: Steiner R, Weisz PB, Langer R, editors. Exs: Angiogenesis Key principles–Science– Tecnology–Medicine. Basel, Boston, Berlin: Birchuser Verlag; 1992. p. 321–6. 42. Albini A, Melchiori A, Garofalo A, Noonan DM, Basolo F, Taraboletti G, Chader GJ, Gavazzi R. Matrigel promotes retinoblastoma cell growth in vitro and in vivo. Int J Cancer. 52:234-40.; 1992. IF=4,700 43. Albini A, Noonan DM, Melchiori A, Fassina GF, Percario M, Gentleman S, Toffenetti J, Chader GJ. Laminin-induced retinoblastoma cell differentiation: possible involvement of a 100kDa cell-surface laminin-binding protein. Proc Natl Acad Sci U S A. 89:2257-61.; 1992. IF=10,231 44. Albini A, Repetto L, Carlone S, Benelli R, Gendelman R, Filippi PD, Bussolino F, Monaco L, Soria M, Parravicini C. Characterization of Kaposi's sarcoma–derived cell cultures from an epidemic and a classic case. Int J Oncol. 1:723–30; 1992. IF=2,681 45. Colacci A, Perocco P, Vaccari M, Lilingardi P, Vià CD, Giovanni CD, Lollini PL, Nanni P, Nicoletti G, Albini A, Parodi S, Grilli S. In vitro assay of halogenated compounds transforming activity as suitable model for studying multistep carcinogenesis. In: Kanduc D, Pani P, editors. Carcinogenesis as Process. Bari; 1992. p. 71–6. 46. Melchiori A, Albini A, Ray JM, Stetler-Stevenson WG. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 52:2353-6.; 1992. IF=7,616 47. Melchiori A, Colacci A, Lollini PL, De Giovanni C, Carlone S, Grilli S, Parodi S, Albini A. Induction of invasive and experimental metastasis potential in BALB/c 3T3 cells by benzo(a)pyrene transformation. Invasion Metastasis. 12:1-11; 1992. IF=1,438 48. Adatia R, Albini A, Colacci A, De Giovanni C, Nanni P, Giunciuglio D, Parodi S, Grilli S, Perocco P. Induction of chemotactic and invasive phenotype in BALB/c 3T3 cells by 1,2dibromoethane transformation. Invasion Metastasis. 13:234-43; 1993. IF=1,438 49. Albini A, Colacci A. Inhibition of malignant tumor cell invasion: an approach to antiprogression. Basic Life Sci. 61:335-50; 1993. 50. Albini A, Melchiori A, Parodi S, Kleinman HK. Chemotaxis and invasiveness. In: Lapiere C, Krieg T, editors. Connective Tissue Diseases of the Skin. New York: Marcel Dekker, Inc.; 1993. p. 129–46. 51. Clerico L, Mancuso T, Noonan D, Albini A. Oncosuppressor genes: mechanisms of inactivation for the retinoblastoma gene and p53. Boll Soc Ital Biol Sper. 69:725-34.; 1993. 52. Colacci A, Albini A, Melchiori A, Nanni P, Nicoletti G, Noonan D, Parodi S, Grilli S. Induction of a malignant phenotype in BALB/c 3T3 cells by 1,1,2,2–tetrachloroethane. Int J Oncol. 2:937–45; 1993. IF=2,681 53. Fassina G, Paglialunga G, Noonan DM, Chader GJ, Albini A. Modulation of Y–79 retinoblastoma and IRBP expression by dibutyryl cyclic AMP and laminin. Int J Oncol. 2:74551; 1993. IF=2,681 54. Mastroianni A, Invernizzi L, Tagliabue E, Fassina G, Albini A, Menard S, Colnaghi MI. Alteration of laminin production in small-cell lung carcinoma: possible correlation with the absence of the basement membrane. Tumour Biol. 14:279-87; 1993. IF=1,235 55. Albini A. Kaposi's sarcoma, vascular permeability, and scientific integrity [Letter]. Jama. 272:919-20; discussion 22-4.; 1994. IF=6,863 56. Albini A, Fontanini G, Masiello L, Tacchetti C, Bigini D, Luzzi P, Noonan DM, StetlerStevenson WG. Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2. Aids. 8:1237-44.; 1994. IF=5,835 57. Balzac F, Retta SF, Albini A, Melchiorri A, Koteliansky VE, Geuna M, Silengo L, Tarone G. Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility. J Cell Biol. 127:557-65.; 1994. IF=10,951 58. Barbanti-Brodano G, Sampaolesi R, Campioni D, Lazzarin L, Altavilla G, Possati L, Masiello L, Benelli R, Albini A, Corallini A. HIV-1 tat acts as a growth factor and induces angiogenic activity in BK virus/tat transgenic mice. Antibiot Chemother. 46:88-101; 1994. 59. Benelli R, Adatia R, Ensoli B, Stetler-Stevenson WG, Santi L, Albini A. Inhibition of AIDSKaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy. Oncol Res. 6:251-7; 1994. IF=1,844 60. Benelli R, Repetto L, Carlone S, Parravicini C, Albini A. Establishment and characterization of two new Kaposi's sarcoma cell cultures from an AIDS and a non-AIDS patient. Res Virol. 145:251-9.; 1994. IF=3,154 61. Gaetano C, Melchiori A, Albini A, Benelli R, Falcioni R, Modesti A, Modica A, Scarpa S, Sacchi A. Retinoic acid negatively regulates beta 4 integrin expression and suppresses the malignant phenotype in a Lewis lung carcinoma cell line. Clin Exp Metastasis. 12:63-72.; 1994. IF=2,811 62. Sciacca FL, Sturzl M, Bussolino F, Sironi M, Brandstetter H, Zietz C, Zhou D, Matteucci C, Peri G, Sozzani S, Benelli R, Arese M, Albini A, Colotta F, Mantovani A. Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells. J Immunol. 153:4816-25; 1994. IF=6,387 63. Soldi R, Graziani A, Benelli R, Ghigo D, Bosia A, Albini A, Bussolino F. Oncostatin M activates phosphatidylinositol-3-kinase in Kaposi's sarcoma cells. Oncogene. 9:2253-60.; 1994. IF=6,872 64. Adatia R, Aluigi MG, Albini A. Biological Mechanisms of Invasion and Metastasis - Review. Acta Medica Romana. 33:493–500; 1995. 65. Albini A, Barillari G, Benelli R, Gallo RC, Ensoli B. Angiogenic properties of human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci U S A. 92:4838-42.; 1995. IF=10,231 66. Albini A, D'Agostini F, Giunciuglio D, Paglieri I, Balansky R, De Flora S. Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine. Int J Cancer. 61:121-9.; 1995. IF=4,700 67. Bobola N, Hirsch E, Albini A, Altruda F, Noonan D, Ravazzolo R. A single cis-acting element in a short promoter segment of the gene encoding the interphotoreceptor retinoid-binding protein confers tissue- specific expression. J Biol Chem. 270:1289-94.; 1995. IF=5,854 68. Bussolino F, Arese M, Montrucchio G, Barra L, Primo L, Benelli R, Sanavio F, Aglietta M, Ghigo D, Rola-Pleszczynski MR, Bosia A, Albini A, Camussi G. Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis. J Clin Invest. 96:940-52.; 1995. IF=15,053 69. De Flora S, Cesarone CF, Balansky RM, Albini A, D'Agostini F, Bennicelli C, Bagnasco M, Camoirano A, Scatolini L, Rovida A, et al. Chemopreventive properties and mechanisms of NAcetylcysteine. The experimental background. J Cell Biochem Suppl. 22:33-41; 1995. IF=3,591 70. Descalzi Cancedda F, Melchiori A, Benelli R, Gentili C, Masiello L, Campanile G, Cancedda R, Albini A. Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: dependence on extracellular matrix assembly. Eur J Cell Biol. 66:60-8.; 1995. IF=2,195 71. Fassina G, Paglialunga G, Perrotta A, Fontanini G, Cosimi A, Albini A. Type IV collagenase and TIMP–2 mRNA. Expression in breast and lung carcinoma specimens. J Tumor Marker Oncol. 10:41–3; 1995. IF=0,250 72. Giunciuglio D, Benelli R, Masiello L, Paglieri I, Pesarini A, Presta M, Noonan DM, Albini A. Mechanisms of Kaposi's sarcoma cell supernatant–induced vascular cell invasion. Int J Oncol. 6:539–46; 1995. IF=2,681 73. Giunciuglio D, Cai T, Filanti C, Manduca P, Albini A. Effect of osteoblast supernatants on cancer cell migration and invasion. Cancer Lett. 97:69-74.; 1995. IF=3,049 74. Giunciuglio D, Culty M, Fassina G, Masiello L, Melchiori A, Paglialunga G, Arand G, Ciardiello F, Basolo F, Thompson EW, Albini A. Invasive phenotype of MCF10A cells overexpressing c-Ha-ras and c-erbB-2 oncogenes. Int J Cancer. 63:815-22; 1995. IF=4,700 75. Melchiori A, Mortarini R, Carlone S, Marchisio PC, Anichini A, Noonan DM, Albini A. The alpha 3 beta 1 integrin is involved in melanoma cell migration and invasion. Exp Cell Res. 219:233-42.; 1995. IF=4,148. 76. Stringa E, Filanti C, Giunciuglio D, Albini A, Manduca P. Osteoblastic cells from rat long bone. I. Characterization of their differentiation in culture. Bone. 16:663-70; 1995. IF=3,939 77. Albini A, Aluigi M, Benelli R, Berti E, Biberfeld P, Blasig C, Calabrò ML, Calvo F, Chieco– Bianchi L, Corbellino M, Mistro AD, Ekman M, Favero A, Hofschneider PH, Kaaya E, Lebbé C, Morel P, Neipel F, Noonan D, Parravicini C, Repetto L, Schalling M, Stürzl M, Tschachler A. Oncogenesis in HIV Infection: HSHV and Kaposi'sarcoma. Int J Oncol. 9:5–8; 1996. IF=2,681 78. Albini A, Benelli R, Presta M, Rusnati M, Ziche M, Rubartelli A, Paglialunga G, Bussolino F, Noonan D. HIV-tat protein is a heparin-binding angiogenic growth factor. Oncogene. 12:28997.; 1996. IF=6,872 79. Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F. The angiogenesis induced by HIV-1 tat protein is mediated by the Flk- 1/KDR receptor on vascular endothelial cells. Nat Med. 2:1371-5.; 1996. IF=28,878 80. Aluigi MG, Albini A, Carlone S, Repetto L, De Marchi R, Icardi A, Moro M, Noonan D, Benelli R. KSHV sequences in biopsies and cultured spindle cells of epidemic, iatrogenic and Mediterranean forms of Kaposi's sarcoma. Res Virol. 147:267-75.; 1996. IF=3,154 81. Aluigi MG, Cai T, Gentleman S, Wong P, Albini A, Noonan DM, Fassina G. Induction of differentiation and apoptosis in retinoblastoma cells by cAMP analogs and laminin. Fund Clin Immun. 4 suppl:23–5; 1996. IF=0,857 82. Benelli R, Albini A, Parravicini C, Carlone S, Repetto L, Tambussi G, Lazzarin A. Isolation of spindle-shaped cell populations from primary cultures of Kaposi's sarcoma of different stage. Cancer Lett. 100:125-32.; 1996. IF=3,049 83. Bussolino F, Albini A, Camussi G, Presta M, Viglietto G, Ziche M, Persico G. Role of soluble mediators in angiogenesis. Eur J Cancer. 32A:2401-12.; 1996. IF=3,706 84. Corallini A, Campioni D, Rossi C, Albini A, Possati L, Rusnati M, Gazzanelli G, Benelli R, Masiello L, Sparacciari V, Presta M, Mannello F, Fontanini G, Barbanti-Brodano G. Promotion of tumour metastases and induction of angiogenesis by native HIV-1 Tat protein from BK virus/tat transgenic mice. Aids. 10:701-10; 1996. IF=5,835 85. Cornali E, Zietz C, Benelli R, Weninger W, Masiello L, Breier G, Tschachler E, Albini A, Sturzl M. Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma. Am J Pathol. 149:1851-69.; 1996. IF=5,796 86. De Flora S, D'Agostini F, Masiello L, Giunciuglio D, Albini A. Synergism between Nacetylcysteine and doxorubicin in the prevention of tumorigenicity and metastasis in murine models. Int J Cancer. 67:842-8.; 1996. IF=2,681 87. Fassina G, Paglialunga G, Fontanini G, Cosimi A, Perrotta A, Ardizzoni A, Aluigi MG, Albini A. Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissues samples derived from breast and lung carcinomas. Int J Oncol. 8:253–61; 1996. IF=2,681 88. Gualandris A, Rusnati M, Belleri M, Molinari–Tosatti MP, Bonardi F, Albini A, Ziche M, Presta M. Angiogenic phenotype induced by basic fibroblast growth ractor transfection in brain microvascular endothelial cells: an in vitro autocrine model of angiogenesis in brain tumors. Int J Oncol. 8:567–73; 1996. IF=2,681 89. Gualandris A, Rusnati M, Belleri M, Nelli EE, Bastaki M, Molinari-Tosatti MP, Bonardi F, Parolini S, Albini A, Morbidelli L, Ziche M, Corallini A, Possati L, Vacca A, Ribatti D, Presta M. Basic fibroblast growth factor overexpression in endothelial cells: an autocrine mechanism for angiogenesis and angioproliferative diseases. Cell Growth Differ. 7:147-60; 1996. IF=3,826 90. Maier JA, Mariotti M, Albini A, Comi P, Prat M, Comogilio PM, Soria MR. Over-expression of hepatocyte growth factor in human Kaposi's sarcoma. Int J Cancer. 65:168-72; 1996. IF=4,700 91. Monini P, Rotola A, de Lellis L, Corallini A, Secchiero P, Albini A, Benelli R, Parravicini C, Barbanti-Brodano G, Cassai E. Latent BK virus infection and Kaposi's sarcoma pathogenesis. Int J Cancer. 66:717-22; 1996. IF=4,700 92. Valente P, Melchiori A, Paggi MG, Masiello L, Ribatti D, Santi L, Takahashi R, Albini A, Noonan DM. RB1 oncosuppressor gene over-expression inhibits tumor progression and induces melanogenesis in metastatic melanoma cells. Oncogene. 13:1169-78.; 1996. IF=6,872 93. Valente P, Noonan DM, Ogle RC, Albini A. Altered production of laminin and nidogen by high and low metastatic variants of murine melanoma cells. Oncol Res. 8:131-8; 1996. IF=1,844 94. Adatia R, Albini A, Carlone S, Giunciuglio D, Benelli R, Santi L, Noonan DM. Suppression of invasive behavior of melanoma cells by stable expression of anti-sense perlecan cDNA. Ann Oncol. 8:1257-61; 1997. IF=4,319 95. Albini A, Paglieri I, Orengo G, Carlone S, Aluigi MG, DeMarchi R, Matteucci C, Mantovani A, Carozzi F, Donini S, Benelli R. The beta-core fragment of human chorionic gonadotrophin inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line. Aids. 11:713-21.; 1997. IF=5,835 96. Benelli R, Masiello L, Paglialunga G, Noonan DM, Repetto L, Carlone S, Orengo G, Fontanini G, Albini A. IFNalpha inhibits tat–induced angiogenesis. In: Guenounou M, editor. Research in Hiv and Cytokines. Paris: INSERM; 1997. p. 447–58. 97. Carlevaro MF, Albini A, Ribatti D, Gentili C, Benelli R, Cermelli S, Cancedda R, Cancedda FD. Transferrin promotes endothelial cell migration and invasion: implication in cartilage neovascularization. J Cell Biol. 136:1375-84.; 1997. IF=10,951 98. Fassina G, Aluigi MG, Gentleman S, Wong P, Cai T, Albini A, Noonan DM. The cAMP analog 8-Cl-cAMP inhibits growth and induces differentiation and apoptosis in retinoblastoma cells. Int J Cancer. 72:1088-94.; 1997. IF=4,700 99. Gualandris A, Lopez Conejo T, Giunciuglio D, Albini A, Sabini E, Rusnati M, Dell'Era P, Presta M. Urokinase-type plasminogen activator overexpression enhances the invasive capacity of endothelial cells. Microvasc Res. 53:254-60.; 1997. IF=2,362 100. Lang ME, Lottersberger C, Roth B, Bock G, Recheis H, Sgonc R, Sturzl M, Albini A, Tschachler E, Zangerle R, Donini S, Feichtinger H, Schwarz S. Induction of apoptosis in Kaposi's sarcoma spindle cell cultures by the subunits of human chorionic gonadotropin. Aids. 11:1333-40.; 1997. IF=5,835 101. Loprevite M, Varesco L, Favoni R, Ferrara GB, Moro F, Ottaggio L, Fronza G, Campomenosi P, Abbondandolo A, Cutrona G, Roncella S, Albini A, Aluigi MG, Pozzi S, Pera C, Biticchi R, Gismondi V, Grossi F, Pennucci M, Ardizzoni A. Analysis of K– ras, p53, bcl–2 and Rb expression in non–small cell lung cancer cell lines. Int J Oncol. 11:1203–08; 1997. IF=2,681 102. Rusnati M, Coltrini D, Oreste P, Zoppetti G, Albini A, Noonan D, di Fagagna F, Giacca M, Presta M. Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size. J Biol Chem. 272:11313-20.; 1997. IF=5,854 103. Albini A. Tumor and endothelial cell invasion of basement membranes. The matrigel chemoinvasion assay as a tool for dissecting molecular mechanisms. Pathol Oncol Res. 4:23041; 1998. IF=1,162 104. Albini A, Benelli R, Giunciuglio D, Cai T, Mariani G, Ferrini S, Noonan DM. Identification of a novel domain of HIV tat involved in monocyte chemotaxis. J Biol Chem. 273:15895-900.; 1998. IF=5,854 105. Albini A, Ferrini S, Benelli R, Sforzini S, Giunciuglio D, Aluigi MG, Proudfoot AE, Alouani S, Wells TN, Mariani G, Rabin RL, Farber JM, Noonan DM. HIV-1 Tat protein mimicry of chemokines. Proc Natl Acad Sci U S A. 95:13153-8; 1998. IF=10,231 106. Benelli R, Mortarini R, Anichini A, Giunciuglio D, Noonan DM, Montalti S, Tacchetti C, Albini A. Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides. Aids. 12:261-8.; 1998. IF=5,835 107. D'Agostini F, Bagnasco M, Giunciuglio D, Albini A, De Flora S. Inhibition by oral Nacetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice. Int J Oncol. 13:217-24; 1998. IF=2,681 108. Festuccia C, Guerra F, D'Ascenzo S, Giunciuglio D, Albini A, Bologna M. In vitro regulation of pericellular proteolysis in prostatic tumor cells treated with bombesin. Int J Cancer. 75:418-31.; 1998. IF=4,700 109. Iurlaro M, Benelli R, Masiello L, Rosso M, Santi L, Albini A. beta Interferon inhibits HIV-1 Tat-induced angiogenesis: synergism with 13-cis retinoic acid. Eur J Cancer. 34:570-6.; 1998. IF=3,706 110. Noonan D, Albini A. Anti-KS activity still a mystery [Letter]. Nat Med. 4:748.; 1998. IF=28,878 111. Vacca A, Ribatti D, Iurlaro M, Albini A, Minischetti M, Bussolino F, Pellegrino A, Ria R, Rusnati M, Presta M, Vincenti V, Persico MG, Dammacco F. Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis. Int J Clin Lab Res. 28:55-68; 1998. IF=1,039 112. Valente P, Fassina G, Melchiori A, Masiello L, Cilli M, Vacca A, Onisto M, Santi L, Stetler-Stevenson WG, Albini A. TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int J Cancer. 75:246-53.; 1998. IF=4,700 113. Albini A, Florio T, Giunciuglio D, Masiello L, Carlone S, Corsaro A, Thellung S, Cai T, Noonan DM, Schettini G. Somatostatin controls Kaposi's sarcoma tumor growth through inhibition of angiogenesis. Faseb J. 13:647-55.; 1999. IF=7,064 114. Albini A, Noonan D, Santi L. Angiogenesis at the interface between basic and clinical research. Int J Biol Markers. 14:202-6.; 1999. IF=1,098 115. Basolo F, Fiore L, Fusco A, Giannini R, Albini A, Merlo GR, Fontanini G, Conaldi PG, Toniolo A. Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene. Int J Cancer. 81:956-62.; 1999. IF=4,700 116. Benelli R, Albini A. In vitro models of angiogenesis: the use of Matrigel. Int J Biol Markers. 14:243-6.; 1999. IF=1,098 117. Biancone L, Cantaluppi V, Boccellino M, Bussolati B, Del Sorbo L, Conaldi PG, Albini A, Toniolo A, Camussi G. Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis. Am J Pathol. 155:1731-9.; 1999. IF=5,796 118. Biancone L, Cantaluppi V, Boccellino M, Del Sorbo L, Russo S, Albini A, Stamenkovic I, Camussi G. Activation of CD40 favors the growth and vascularization of Kaposi's sarcoma. J Immunol. 163:6201-8.; 1999. IF=6,387 119. Cai T, Fassina G, Morini M, Aluigi MG, Masiello L, Fontanini G, D'Agostini F, De Flora S, Noonan DM, Albini A. N-acetylcysteine inhibits endothelial cell invasion and angiogenesis. Lab Invest. 79:1151-9.; 1999. IF=4,165 120. Coulibaly S, Schwihla H, Abrahamson M, Albini A, Cerni C, Clark JL, Ng KM, Katunuma N, Schlappack O, Glossl J, Mach L. Modulation of invasive properties of murine squamous carcinoma cells by heterologous expression of cathepsin B and cystatin C. Int J Cancer. 83:526-31.; 1999. IF=4,700 121. Festuccia C, Giunciuglio D, Guerra F, Villanova I, Angelucci A, Manduca P, Teti A, Albini A, Bologna M. Osteoblasts modulate secretion of urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) in human prostate cancer cells promoting migration and matrigel invasion. Oncol Res. 11:17-31; 1999. IF=1,844 122. Garbisa S, Biggin S, Cavallarin N, Sartor L, Benelli R, Albini A. Tumor invasion: molecular shears blunted by green tea. Nat Med. 5:1216.; 1999. IF=28,878 123. Indraccolo S, Minuzzo S, Gola E, Habeler W, Carrozzino F, Noonan D, Albini A, Santi L, Amadori A, Chieco-Bianchi L. Generation of expression plasmids for angiostatin, endostatin and TIMP- 2 for cancer gene therapy. Int J Biol Markers. 14:251-6.; 1999. IF=1,098 124. Marchio S, Primo L, Pagano M, Palestro G, Albini A, Veikkola T, Cascone I, Alitalo K, Bussolino F. Vascular endothelial growth factor-C stimulates the migration and proliferation of Kaposi's sarcoma cells. J Biol Chem. 274:27617-22.; 1999. IF=5,854 125. Marchisone C, Benelli R, Albini A, Santi L, Noonan DM. Inhibition of angiogenesis by type I interferons in models of Kaposi's sarcoma. Int J Biol Markers. 14:257-62.; 1999. IF=1,098 126. Marconcini L, Marchio S, Morbidelli L, Cartocci E, Albini A, Ziche M, Bussolino F, Oliviero S. c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro. Proc Natl Acad Sci U S A. 96:9671-6.; 1999. IF=10,789 127. Morini M, Cai T, Aluigi MG, Noonan DM, Masiello L, De Flora S, D'Agostini F, Albini A, Fassina G. The role of the thiol N-acetylcysteine in the prevention of tumor invasion and angiogenesis. Int J Biol Markers. 14:268-71.; 1999. IF=1,098 128. Taraboletti G, Benelli R, Borsotti P, Rusnati M, Presta M, Giavazzi R, Ruco L, Albini A. Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat- induced angiogenesis and is poorly expressed in KS lesions. J Pathol. 188:76-81.; 1999. IF=6,213 129. Vacca A, Ribatti D, Presta M, Minischetti M, Iurlaro M, Ria R, Albini A, Bussolino F, Dammacco F. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood. 93:3064-73.; 1999. IF=10,131 130. Albini A, Marchisone C, Del Grosso F, Benelli R, Masiello L, Tacchetti C, Bono M, Ferrantini M, Rozera C, Truini M, Belardelli F, Santi L, Noonan DM. Inhibition of angiogenesis and vascular tumor growth by interferon- producing cells: A gene therapy approach. Am J Pathol. 156:1381-93.; 2000. IF=5,796 131. Aluigi MG, De Flora S, D'Agostini F, Albini A, Fassina G. Antiapoptotic and antigenotoxic effects of N-acetylcysteine in human cells of endothelial origin. Anticancer Res. 20:3183-7.; 2000. IF=1,604 132. Benelli R, Barbero A, Buffa A, Aluigi MG, Masiello L, Morbidelli L, Ziche M, Albini A, Noonan D. Distinct chemotactic and angiogenic activities of peptides derived from Kaposi's sarcoma virus encoded chemokines. Int J Oncol. 17:75-81.; 2000. IF=2,681 133. Benelli R, Barbero A, Ferrini S, Scapini P, Cassatella M, Bussolino F, Tacchetti C, Noonan DM, Albini A. Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis. J Infect Dis. 182:1643-51.; 2000. IF=4,953 134. Biroccio A, Candiloro A, Mottolese M, Sapora O, Albini A, Zupi G, Del Bufalo D. Bcl2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line. Faseb J. 14:652-60.; 2000. IF=7,064 135. Di Carlo E, Comes A, Basso S, De Ambrosis A, Meazza R, Musiani P, Moelling K, Albini A, Ferrini S. The combined action of IL-15 and IL-12 gene transfer can induce tumor cell rejection without T and NK cell involvement. J Immunol. 165:3111-8.; 2000. IF=6,387 136. Fassina G, Ferrari N, Brigati C, Benelli R, Santi L, Noonan DM, Albini A. Tissue inhibitors of metalloproteases: regulation and biological activities. Clin Exp Metastasis. 18:11120; 2000. IF=2,811 137. Festuccia C, Angelucci A, Gravina GL, Villanova II, Teti A, Albini A, Bologna M. Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells. Int J Cancer. 86:888; 2000. IF=4,700 138. Ghezzi S, Noonan DM, Aluigi MG, Vallanti G, Cota M, Benelli R, Morini M, Reeves JD, Vicenzi E, Poli G, Albini A. Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat. Biochem Biophys Res Commun. 270:992-6.; 2000. IF=3,000 139. Giavazzi R, Albini A, Bussolino F, DeBraud F, Presta M, Ziche M, Costa A. The biological basis for antiangiogenic therapy. Eur J Cancer. 36:1913-8.; 2000. IF=3,706 140. Marchisone C, Pfeffer U, Del Grosso F, Noonan DM, Santi L, Albini A. Progress towards gene therapy for cancer. J Exp Clin Cancer Res. 19:261-70.; 2000. IF=0,540 141. Montaldo F, Maffe A, Morini M, Noonan D, Giordano S, Albini A, Prat M. Expression of functional tyrosine kinases on immortalized Kaposi's sarcoma cells. J Cell Physiol. 184:24654.; 2000. IF=4,362 142. Morini M, Benelli R, Giunciuglio D, Carlone S, Arena G, Noonan DM, Albini A. Kaposi's sarcoma cells of different etiologic origins respond to HIV- Tat through the Flk1/KDR (VEGFR-2): relevance in AIDS-KS pathology. Biochem Biophys Res Commun. 273:267-71.; 2000. IF=3,000 143. Morini M, Mottolese M, Ferrari N, Ghiorzo F, Buglioni S, Mortarini R, Noonan DM, Natali PG, Albini A. The alpha 3 beta 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity. Int J Cancer. 87:336-42.; 2000. IF=4,700 144. Noonan DM, Albini A. From the outside in: extracellular activities of HIV Tat. In: Jeang KT, editor. HIV: Molecular Mechanisms and Clinical Applications. San Diego, CA: Academic Press; 2000. p. 229-50. 145. Rusnati M, Taraboletti G, Urbinati C, Tulipano G, Giuliani R, Molinari-Tosatti MP, Sennino B, Giacca M, Tyagi M, Albini A, Noonan D, Giavazzi R, Presta M. Thrombospondin1/HIV-1 tat protein interaction: modulation of the biological activity of extracellular Tat. Faseb J. 14:1917-30; 2000. IF=7,064 146. Tosi G, Meazza R, De Lerma Barbaro A, D'Agostino A, Mazza S, Corradin G, Albini A, Noonan DM, Ferrini S, Accolla RS. Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR. Eur J Immunol. 30:1120-6.; 2000. IF=4,876 147. Vene R, Benelli R, Noonan DM, Albini A. HIV-Tat dependent chemotaxis and invasion, key aspects of tat mediated pathogenesis. Clin Exp Metastasis. 18:533-8; 2000. IF=2,811 148. Albini A, Morini M, D'Agostini F, Ferrari N, Campelli F, Arena G, Noonan DM, Pesce C, De Flora S. Inhibition of angiogenesis-driven Kaposi's sarcoma tumor growth in nude mice by oral N-acetylcysteine. Cancer Res. 61:8171-8; 2001. IF=7,616 149. Bagnato A, Rosano L, Di Castro V, Albini A, Salani D, Varmi M, Nicotra MR, Natali PG. Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells. Am J Pathol. 158:841-7.; 2001. IF=5,796 150. Barbero A, Benelli R, Minghelli S, Tosetti F, Dorcaratto A, Ponzetto C, Wernig A, Cullen MJ, Albini A, Noonan DM. Growth factor supplemented matrigel improves ectopic skeletal muscle formation--a cell therapy approach. J Cell Physiol. 186:183-92.; 2001. IF=4,362 151. Bonavia R, Bajetto A, Barbero S, Albini A, Noonan DM, Schettini G. HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons. Biochem Biophys Res Commun. 288:301-8.; 2001. IF=3,000 152. Cantaluppi V, Biancone L, Boccellino M, Doublier S, Benelli R, Carlone S, Albini A, Camussi G. Hiv type 1 tat protein is a survival factor for kaposi's sarcoma and endothelial cells. AIDS Res Hum Retroviruses. 17:965-76.; 2001. IF=2,531 153. Casalone R, Albini A, Righi R, Granata P, Toniolo A. Nonrandom chromosome changes in Kaposi sarcoma: cytogenetic and FISH results in a new cell line (KS-IMM) and literature review. Cancer Genet Cytogenet. 124:16-9.; 2001. IF=1,640 154. Corsaro A, Thellung S, Villa V, Arena S, Noonan D, Albini A, Schettini G, Florio T. Somatostatinergic control of Kaposi's sarcoma growth through the inhibition of angiogenesis. Minerva Endocrinol. 26:273-6.; 2001. 155. De Flora S, Izzotti A, D'Agostini F, Balansky RM, Noonan D, Albini A. Multiple points of intervention in the prevention of cancer and other mutation-related diseases. Mutat Res. 480481:9-22.; 2001. IF=3,340 156. Fazekas K, Janovics A, Dome B, Koska P, Albini A, Timar J. Effect of HGF-like basic hexapeptides on angiogenesis. Microvasc Res. 62:440-4.; 2001. IF=2,362 157. Garbisa S, Sartor L, Biggin S, Salvato B, Benelli R, Albini A. Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate. Cancer. 91:822-32; 2001. IF=4,800 158. Indraccolo S, Morini M, Gola E, Carrozzino F, Habeler W, Minghelli S, Santi L, Chieco-Bianchi L, Cao Y, Albini A, Noonan DM. Effects of angiostatin gene transfer on functional properties and in vivo growth of kaposi's sarcoma cells. Cancer Res. 61:5441-6.; 2001. IF=7,616 159. Lorusso G, Dell'Eva R, Vene R, Pfeffer U, Albini A. Rationale, problems and perspectives in anti-angiogenic therapy. Tumori. 87:S17-9.; 2001. 160. Rusnati M, Urbinati C, Musulin B, Ribatti D, Albini A, Noonan D, Marchisone C, Waltenberger J, Presta M. Activation of endothelial cell mitogen activated protein kinase ERK(1/2) by extracellular HIV-1 Tat protein. Endothelium. 8:65-74; 2001. IF=2,343 161. Baldi A, De Luca A, Morini M, Battista T, Felsani A, Baldi F, Catricala C, Amantea A, Noonan DM, Albini A, Natali PG, Lombardi D, Paggi MG. The HtrA1 serine protease is downregulated during human melanoma progression and represses growth of metastatic melanoma cells. Oncogene. 21:6684-8.; 2002. IF=6,872 162. Benelli R, Morini M, Carrozzino F, Ferrari N, Minghelli S, Santi L, Cassatella M, Noonan DM, Albini A. Neutrophils as a key cellular target for angiostatin: implications for regulation of angiogenesis and inflammation. Faseb J. 16:267-9.; 2002. IF=7,064 163. Benelli R, Vene R, Bisacchi D, Garbisa S, Albini A. Anti-invasive effects of green tea polyphenol epigallocatechin-3- gallate (EGCG), a natural inhibitor of metallo and serine proteases. Biol Chem. 383:101-5.; 2002. IF=2,577 164. Bisacchi D, Noonan DM, Carlone S, Albini A, Pfeffer U. Kaposi's sarcoma and human chorionic gonadotropin: mechanisms, moieties and mysteries. Biol Chem. 383:1315-20.; 2002. 165. Brigati C, Noonan DM, Albini A, Benelli R. Tumors and inflammatory infiltrates: friends or foes? Clin Exp Metastasis. 19:247-58; 2002. IF=2,811 166. Cassoni P, Sapino A, Deaglio S, Bussolati B, Volante M, Munaron L, Albini A, Torrisi A, Bussolati G. Oxytocin Is a Growth Factor for Kaposi's Sarcoma Cells: Evidence of Endocrine-Immunological Cross-Talk. Cancer Res. 62:2406-13.; 2002. IF=7,616 167. Dell'Eva R, Pfeffer U, Indraccolo S, Albini A, Noonan D. Inhibition of tumor angiogenesis by angiostatin: from recombinant protein to gene therapy. Endothelium. 9:3-10; 2002. IF=2,343 168. Deregibus MC, Cantaluppi V, Doublier S, Brizzi MF, Deambrosis I, Albini A, Camussi G. HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT- dependent survival pathways in Kaposi's sarcoma cells. J Biol Chem. 277:25195-202.; 2002. IF=5,854 169. Fassina G, Buffa A, Benelli R, Varnier OE, Noonan DM, Albini A. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent. Aids. 16:939-41.; 2002. IF=5,835 170. Giannelli G, Astigiano S, Antonaci S, Morini M, Barbieri O, Noonan DM, Albini A. Role of the alpha3beta1 and alpha6beta4 integrins in tumor invasion. Clin Exp Metastasis. 19:217-23; 2002. IF=2,811 171. Indraccolo S, Gola E, Rosato A, Minuzzo S, Habeler W, Tisato V, Roni V, Esposito G, Morini M, Albini A, Noonan DM, Ferrantini M, Amadori A, Chieco-Bianchi L. Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells. Gene Ther. 9:867-78.; 2002. IF=4,836 172. Lollini PL, Pierotti MA, Passerini CG, Bani MR, Zupi G, Aglietta M, Albini A.. New challenges of molecular oncology. Tumori. 88:77-81.; 2002. 173. Pfeffer U, Bisacchi D, Morini M, Benelli R, Minghelli S, Vacca A, Noonan DM, Albini A. Human chorionic gonadotropin inhibits Kaposi's sarcoma associated angiogenesis, matrix metalloprotease activity, and tumor growth. Endocrinology. 143:3114-21; 2002. IF=5,313 174. Scapini P, Nesi L, Morini M, Tanghetti E, Belleri M, Noonan D, Presta M, Albini A, Cassatella MA. Generation of biologically active angiostatin kringle 1-3 by activated human neutrophils. J Immunol. 168:5798-804.; 2002. IF=6,387 175. Tosetti F, Benelli R, Albini A. The angiogenic switch in solid tumors: clinical implications. Suppl Tumori. 1:S9-11.; 2002. IF=0,739 176. Tosetti F, Ferrari N, De Flora S, Albini A. Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents. Faseb J. 16:2-14.; 2002. IF=7,064 177. Benelli R, Albini A, Noonan D. Neutrophils and angiogenesis: potential initiators of the angiogenic cascade. Chem Immunol Allergy. 83:167-81; 2003. 178. Benelli R, Morini M, Brigati C, Noonan DM, Albini A. Angiostatin inhibits extracellular HIV-Tat-induced inflammatory angiogenesis. Int J Oncol. 22:87-91.; 2003. IF=2,571 179. Benelli R, Peissel B, Manenti G, Gariboldi M, Vanzetto C, Albini A, Dragani TA. Allele-specific patterns of the mouse parathyroid hormone-related protein: influences on cell adhesion and migration. Oncogene. 22:7711-5; 2003. IF=7,414 180. Bisacchi D, Benelli R, Vanzetto C, Ferrari N, Tosetti F, Albini A. Anti-angiogenesis and angioprevention: mechanisms, problems and perspectives. Cancer Detect Prev. 27:229-38.; 2003. IF=1,918 181. Borghi R, Vene R, Arena G, Schubert D, Albini A, Tosetti F. Transient modulation of cytoplasmic and nuclear retinoid receptors expression in differentiating human teratocarcinoma NT2 cells. J Neurochem. 84:94-104.; 2003. IF=4,337 182. Brigati C, Giacca M, Noonan DM, Albini A. HIV Tat, its TARgets and the control of viral gene expression. FEMS Microbiol Lett. 220:57-65.; 2003. IF=2,04 183. Donà M, Dell'Aica I, Calabrese F, Benelli R, Morini M, Albini A, Garbisa S. Neutrophil restraint by green tea: inhibition of inflammation, associated angiogenesis, and pulmonary fibrosis. J Immunol. 170:4335-41.; 2003. IF=5,745 184. Ferrari N, Morini M, Pfeffer U, Minghelli S, Noonan DM, Albini A. Inhibition of Kaposi's Sarcoma in Vivo by Fenretinide. Clin Cancer Res. 9:6020-9; 2003. IF=7,338 185. Ferrari N, Paleari L, Palmisano GL, Tammaro P, Levi G, Albini A, Brigati C. Induction of apoptosis by fenretinide in tumor cell lines correlates with DLX2, DLX3 and DLX4 gene expression. Oncol Rep. 10:973-7.; 2003. IF=1,686 186. Ferrari N, Palmisano GL, Paleari L, Basso G, Mangioni M, Fidanza V, Albini A, Croce CM, Levi G, Brigati C. DLX genes as targets of ALL-1: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias. J Leukoc Biol. 74:302-5; 2003. IF=4,626 187. Florio T, Morini M, Villa V, Arena S, Corsaro A, Thellung S, Culler MD, Pfeffer U, Noonan DM, Schettini G, Albini A. Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogenactivated protein kinase activities. Endocrinology. 144:1574-84.; 2003. IF=4,993 188. Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J Leukoc Biol. 73:584-90.; 2003. IF=4,626 189. Guenzi E, Topolt K, Lubeseder-Martellato C, Jorg A, Naschberger E, Benelli R, Albini A, Sturzl M. The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression. Embo J. 22:3772-82; 2003. IF=10,124 190. Noonan DM, Gringeri A, Meazza R, Rosso O, Mazza S, Muca-Perja M, Le Buanec H, Accolla RS, Albini A, Ferrini S. Identification of immunodominant epitopes in inactivated Tatvaccinated healthy and HIV-1-infected volunteers. J Acquir Immune Defic Syndr. 33:47-55.; 2003. IF=4,262 191. Pezzato E, Dona M, Sartor L, Dell'Aica I, Benelli R, Albini A, Garbisa S. Proteinase-3 directly activates MMP-2 and degrades gelatin and Matrigel; differential inhibition by ()epigallocatechin-3-gallate. J Leukoc Biol. 74:88-94; 2003. IF=4,626 192. Pfeffer U, Ferrari N, Morini M, Benelli R, Noonan DM, Albini A. Antiangiogenic activity of chemopreventive drugs. Int J Biol Markers. 18:70-4.; 2003. IF=1,26 193. Pfeffer U, Noonan D, Albini A. Re: Microarray studies challenge theories of metastasis. J Natl Cancer Inst. 95:829; 2003. IF=14,697 194. Rosano L, Spinella F, Di Castro V, Nicotra MR, Albini A, Natali PG, Bagnato A. Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo. Am J Pathol. 163:753-62; 2003. IF=5,224 195. Tosetti F, Vene R, Arena G, Morini M, Minghelli S, Noonan DM, Albini A. N-(4hydroxyphenyl)retinamide inhibits retinoblastoma growth through reactive oxygen speciesmediated cell death. Mol Pharmacol. 63:565-73.; 2003. IF=4,725 196. Albini A, Benelli R, Noonan DM, Brigati C. The "chemoinvasion assay": a tool to study tumor and endothelial cell invasion of basement membranes. Int J Dev Biol. 48:563-71; 2004. IF=2,856 197. Fassina G, Vene R, Morini M, Minghelli S, Benelli R, Noonan DM, Albini A. Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin Cancer Res. 10:4865-73; 2004. IF=7,338 198. Forster-Horvath C, Meszaros L, Raso E, Dome B, Ladanyi A, Morini M, Albini A, Timar J. Expression of CD44v3 protein in human endothelial cells in vitro and in tumoral microvessels in vivo. Microvasc Res. 68:110-8; 2004. IF=2,39 199. Morini M, Albini A, Lorusso G, Moelling K, Lu B, Cilli M, Ferrini S, Noonan DM. Prevention of angiogenesis by naked DNA IL-12 gene transfer: angioprevention by immunogene therapy. Gene Ther. 11:284-91; 2004. IF=4,538 200. Morini M, Roccatagliata L, Dell'Eva R, Pedemonte E, Furlan R, Minghelli S, Giunti D, Pfeffer U, Marchese M, Noonan D, Mancardi G, Albini A, Uccelli A. Alpha-lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis. J Neuroimmunol. 148:146-53; 2004. IF=2,901 201. Raso E, Meszaros L, Albini A, Timar J. A WT1 expressing metastatic human Kaposi sarcoma xenograft model. Pathol Oncol Res. 10:22-5; 2004. IF=1,483 202. Rossello A, Nuti E, Orlandini E, Carelli P, Rapposelli S, Macchia M, Minutolo F, Carbonaro L, Albini A, Benelli R, Cercignani G, Murphy G, Balsamo A. New N-arylsulfonylN-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2). Bioorg Med Chem. 12:2441-50; 2004. IF=2,978 203. Sartor L, Pezzato E, Dona M, Dell'Aica I, Calabrese F, Morini M, Albini A, Garbisa S. Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model. Int J Cancer. 112:823-9; 2004. IF=4,926 204. Scapini P, Morini M, Tecchio C, Minghelli S, Di Carlo E, Tanghetti E, Albini A, Lowell C, Berton G, Noonan DM, Cassatella MA. CXCL1/macrophage inflammatory protein-2induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A. J Immunol. 172:5034-40; 2004. IF=5,745 205. Dell’Eva R, Pfeffer U, Vené R, Anfosso L, Forlani A, Albini A, Efferth T. Inhibition of angiogenesis in vivo and growth of Kaposi’s sarcoma xenograft tumors by the anti-malarial artesunate. Biochem Pharmacol. 68(12):2359-66; 2004. IF=4,889 206. Zacchigna S, Zentilin L, Morini M, Dell'Eva R, Noonan DM, Albini A, Giacca M. AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo. Cancer Gene Ther. 11:73-80; 2004. IF=3,744 207. Albini A, Noonan DM. Rescuing COX-2 Inhibitors From the Waste Bin [Letter]. J Natl Cancer Inst. Jun 1;97(11):859-60. 2005 IF=14,697 208. Albini A, Tosetti F, Benelli R, Noonan DM. Tumor inflammatory angiogenesis and its chemoprevention. Cancer Res. 65:10637-41; 2005. IF=8,234 209. Bachmeier B, Vene R, Iancu C, Pfeffer U, Mayer B, Noonan D, Albini A, Jochum M, Nerlich A. Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines. Thromb Haemost. 93:761-9; 2005. IF=4,701 210. Bachmeier BE, Albini A, Vene R, Benelli R, Noonan D, Weigert C, Weiler C, Lichtinghagen R, Jochum M, Nerlich AG. Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines. Exp Cell Res. 305:83-98; 2005. IF=3,609 211. Ferrari N, Pfeffer U, Dell'Eva R, Ambrosini C, Noonan DM, Albini A. The transforming growth factor-beta family members bone morphogenetic protein-2 and macrophage inhibitory cytokine-1 as mediators of the antiangiogenic activity of N-(4-hydroxyphenyl)retinamide. Clin Cancer Res. 11:4610-9; 2005. IF=7,338 212. Margheri F, D'Alessio S, Serrati S, Pucci M, Del Rosso A, Benelli R, Ferrari N, Noonan DM, Albini A, Fibbi G, Del Rosso M. The urokinase-type plasminogen activator, its receptor and u-PA inhibitor type-1 affect in vitro growth and invasion of Kaposi's sarcoma and capillary endothelial cells: role of HIV-Tat protein. Int J Oncol. 27:223-35; 2005. IF=2,571 213. Noonan DM, Severino A, Morini M, Tritarelli A, Manente L, D'Agnano I, Starace G, Baldi A, Lombardi D, Albini A, Felsani A, Paggi MG. In vitro and in vivo tumor growth inhibition by a p16-mimicking peptide in p16(INK4A)-defective, pRb-positive human melanoma cells. J Cell Physiol. 202:922-8; 2005. IF=3,986 214. Pfeffer U, Ferrari N, Dell'eva R, Indraccolo S, Morini M, Noonan DM, Albini A. Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: Microarray gene expression analyses. Mutat Res. 591:198-211; 2005. IF=3,204 215. Timar J, Meszaros L, Orosz Z, Albini A, Raso E. WT1 expression in angiogenic tumours of the skin. Histopathology. 47:67-73; 2005. IF=3,569 216. Rossello A, Nuti E, Carelli P, Orlandini E, Macchia M, Nencetti S, Zandomeneghi M, Balzano F, Uccello Barretta G, Albini A, Benelli R, Cercignani G, Murphy G, Balsamo A. N-iPropoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP. Bioorg. Med. Chem. Lett. 15(5):1321-6; 2005. IF=2,661 217. Albini A, Dell'Eva R, Vene R, Ferrari N, Buhler DR, Noonan DM, Fassina G. Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets. Faseb J. 20:527-9; 2006. IF=6,515 218. Albini A, Pfeffer U. A new tumor suppressor gene: invasion, metastasis, and angiogenesis as potential key targets. J Natl Cancer Inst. 98:800-1; 2006. IF=14,697 219. Anfosso L, Efferth T, Albini A, Pfeffer U. Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins. Pharmacogenomics J. 6:269-78; 2006. IF=4,306 220. Benelli R, Lorusso G, Albini A, Noonan DM. Cytokines and chemokines as regulators of angiogenesis in health and disease. Curr Pharm Des. 12:3101-15; 2006. IF=4,774 221. Cantaluppi V, Deregibus MC, Biancone L, Deambrosis I, Bussolati B, Albini A, Camussi G. The expression of CD154 by Kaposis sarcoma cells mediates the anti-apoptotic and migratory effects of HIV-1-TAT protein. Int J Immunopathol Pharmacol. 19:81-96; 2006. IF=2,685 222. Cantarella G, Risuglia N, Dell'eva R, Lempereur L, Albini A, Pennisi G, Scoto GM, Noonan DN, Bernardini R. TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells. Br J Cancer. 94:1428-35; 2006. IF=4,831 223. Paleari L, Trombino S, Falugi C, Gallus L, Carlone S, Angelini C, Sepcic K, Turk T, Faimali M, Noonan DM, Albini A. Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors. Int J Oncol. 29:1381-8; 2006. IF=2,571 224. Spinella F, Rosano L, Decandia S, Di Castro V, Albini A, Elia G, Natali PG, Bagnato A. Antitumor effect of green tea polyphenol epigallocatechin-3-gallate in ovarian carcinoma cells: evidence for the endothelin-1 as a potential target. Exp Biol Med (Maywood). 231:1123-7; 2006. IF=2,954 225. Spinella F, Rosano L, Di Castro V, Decandia S, Albini A, Nicotra MR, Natali PG, Bagnato A. Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma. Mol Cancer Ther. 5:1483-92; 2006. IF=5,225 226. Tettamanti G, Malagoli D, Benelli R, Albini A, Grimaldi A, Perletti G, Noonan DM, de Eguileor M, Ottaviani E. Growth factors and chemokines: a comparative functional approach between invertebrates and vertebrates. Curr Med Chem. 13:2737-50; 2006. IF=4,63 227. Tosetti F, Noonan DM, Albini A. Choking hypoxia-inducible factor 1alpha: a novel mechanism for connective tissue growth factor inhibition of angiogenesis. J Natl Cancer Inst. 98:946-8; 2006. IF=15,171 228. Albini A, Benelli R. The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation. Nat Protoc. 2:504-11; 2007. IF=8,362 Albini A, Fassina G, Nicolo M, Dell'Eva R, Vene R, Cammarota R, Barberis M, Noonan 229. DM. Inhibition of a vascular ocular tumor growth by IL-12 gene transfer. Clin Exp Metastasis. 24:485-93; 2007. IF=4,113 230. Albini A, Noonan DM, Ferrari N. Molecular pathways for cancer angioprevention. Clin Cancer Res. 13:4320-5; 2007. IF=7,338 231. Albini A, Sporn MB. The tumour microenvironment as a target for chemoprevention. Nat Rev Cancer. 7:139-47; 2007. IF=37,178 232. Bachmeier B, Nerlich AG, Iancu CM, Cilli M, Schleicher E, Vene R, Dell'Eva R, Jochum M, Albini A, Pfeffer U. The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice. Cell Physiol Biochem. 19:137-52; 2007. IF=3,585 233. Dell'Aica I, Niero R, Piazza F, Cabrelle A, Sartor L, Colalto C, Brunetta E, Lorusso G, Benelli R, Albini A, Calabrese F, Agostini C, Garbisa S. Hyperforin blocks neutrophil activation of matrix metalloproteinase-9, motility and recruitment, and restrains inflammationtriggered angiogenesis and lung fibrosis. J Pharmacol Exp Ther. 321:492-500; 2007. IF=4,017 234. Dell'Eva R, Ambrosini C, Minghelli S, Noonan DM, Albini A, Ferrari N. The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-kappaB pathway. Carcinogenesis. 28:404-13; 2007. IF=5,402 235. Dell'Eva R, Ambrosini C, Vannini N, Piaggio G, Albini A, Ferrari N. AKT/NF-kappaB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignancies. Cancer. 110:2007-11; 2007. IF=5,131 236. Indraccolo S, Pfeffer U, Minuzzo S, Esposito G, Roni V, Mandruzzato S, Ferrari N, Anfosso L, Dell'Eva R, Noonan DM, Chieco-Bianchi L, Albini A, Amadori A. Identification of genes selectively regulated by IFNs in endothelial cells. J Immunol. 178:1122-35; 2007. IF=5,74561. 237. Larghero P, Vene R, Minghelli S, Travaini G, Morini M, Ferrari N, Pfeffer U, Noonan DM, Albini A, Benelli R. Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression. Carcinogenesis. 28:1008-20; 2007. IF=5,402 238. Noonan DM, Benelli R, Albini A. Angiogenesis and cancer prevention: a vision. Recent Results Cancer Res. 174:219-24; 2007. 239. Secchiero P, Corallini F, Gonelli A, Dell'Eva R, Vitale M, Capitani S, Albini A, Zauli G. Antiangiogenic activity of the MDM2 antagonist nutlin-3. Circ Res. 100:61-9; 2007. IF=9,504 240. Vannini N, Lorusso G, Cammarota R, Barberis M, Noonan DM, Sporn MB, Albini A. The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent. Mol Cancer Ther. 6:3139-46; 2007. IF=5,225 241. Vene R, Arena G, Poggi A, D'Arrigo C, Mormino M, Noonan DM, Albini A, Tosetti F. Novel cell death pathways induced by N-(4-hydroxyphenyl)retinamide: therapeutic implications. Mol Cancer Ther. 6:286-98; 2007. IF=5,225 242. Sporn MB, Libi K, Yore MM, Suh N, Albini A, Honda T, Sundararajan C, Gribble GW. Platforms and Networks in Triterpenoid Pharmacology. Drug Dev. Res. 68:174-182; 2007. IF=0,752 243. Albini A. Tumor microenvironment, a dangerous society leading to cancer metastasis. From mechanisms to therapy and prevention. Cancer Metastasis Rev. 27:3-4; 2008. IF=7,14 244. Albini A, Mirisola V, Pfeffer U. Metastasis signatures: genes regulating tumormicroenvironment interactions predict metastatic behavior. Cancer Metastasis Rev. 27:75-83; 2008. IF=7,14 Araldi EM, Dell'aica I, Sogno I, Lorusso G, Garbisa S, Albini A. Natural and synthetic 245. agents targeting inflammation and angiogenesis for chemoprevention of prostate cancer. Curr Cancer Drug Targets. 8:146-55; 2008. IF=4,771 246. Bianco R, Rosa R, Damiano V, Daniele G, Gelardi T, Garofalo S, Tarallo V, De Falco S, Melisi D, Benelli R, Albini A, Ryan A, Ciardiello F, Tortora G. Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells. Clin Cancer Res. 14:5069-80; 2008. IF=7,338 247. Liby K, Risingsong R, Royce DB, Williams CR, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB. Prevention and Treatment of Experimental Estrogen Receptor-Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268. Clin Cancer Res. 14:4556-63; 2008. IF=7,338 248. Miretti S, Roato I, Taulli R, Ponzetto C, Cilli M, Olivero M, Di Renzo MF, Godio L, Albini A, Buracco P, Ferracini R. A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by luciferase imaging. PLoS ONE. 3:e1828; 2008. IF= 4,411 249. Monteghirfo S, Tosetti F, Ambrosini C, Stigliani S, Pozzi S, Frassoni F, Fassina G, Soverini S, Albini A, Ferrari N. Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation. Mol Cancer Ther. 7:2692-702; 2008. IF=5,225 250. Noonan DM, De Lerma Barbaro A, Vannini N, Mortara L, Albini A. Inflammation, inflammatory cells and angiogenesis: decisions and indecisions. Cancer Metastasis Rev. 27:3140; 2008. IF=8,017 251. Vannini N, Pfeffer U, Lorusso G, Noonan DM, Albini A. Endothelial cell aging and apoptosis in prevention and disease: E-selectin expression and modulation as a model. Curr Pharm Des. 14:221-5; 2008. IF=4,774 252. Vene R, Larghero P, Arena G, Sporn MB, Albini A, Tosetti F. Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids. Cancer Res. 68:6987-96; 2008. IF=8,234 253. Abbadessa G, Accolla R, Aiuti F, Albini A, Et. Al. Unsung Hero Robert C. Gallo. Science. 323:206-7; 2009. IF= 31,364 254. Albini A, Brigati C, Ventura A, Lorusso G, Pinter M, Morini M, Mancino A, Sica A, Noonan DM. Angiostatin anti-angiogenesis requires IL-12: the innate immune system as a key target. J Transl Med. 7:5; 2009. IF= 3,508 255. Serrati S, Margheri F, Pucci M, Cantelmo AR, Cammarota R, Dotor J, Borras-Cuesta F, Fibbi G, Albini A, Del Rosso M. TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis. Biochem Pharmacol. 77:813-25; 2009. IF=4,889 256. Sogno H, Vannini N, Lorusso G, Cammarota R, Noonan DM, Generoso L, Sporn MB, Albini A. Anti-angiogenic activity of a novel class of chemopreventive compounds: oleanic acid terpenoids. Recent Results Cancer Res. 181:209-12; 2009. 257. Sogno I, Vene R, Sapienza C, Ferrari N, Tosetti F, Albini A. Anti-angiogenic properties of chemopreventive drugs: fenretinide as a prototype. Recent Results Cancer Res. 181:71-6; 2009. 258. Pfeffer U, Romeo F, Noonan DM, Albini A. Prediction of breast cancer metastasis by genomic profiling: where do we stand?. Clin Exp Metastasis. 2009 Mar 24. IF= 4,113 259. Lorusso G, Vannini N, Sogno I, Generoso L, Garbisa S, Noonan DM, Albini A. Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent. Eur J Cancer. 2009 May;45(8):1474-84. IF= 4,944 260. Wang E, Albini A, Stroncek DF, Marincola FM. New take on comparative immunology: relevance to immunotherapy. Immunotherapy 2009 1(3), 355-366. IF=0,542 Margheri F, Serratì S, Lapucci A, Chillà A, Giusti B, Pucci M, Torre E, Bianchini F, 261. Calorini L, Albini A, Ventura A, Fibbi G, Del Rosso M. Systemic sclerosis-endothelial cell antiangiogenic Pentraxin 3 and Matrix Metalloprotease 12 control human breast cancer tumor vascolarization and development in mice. Neoplasia 2009– 10: 1106-1115;. IF=5,476 262. Alessi P, Leali D, Camozzi M, Cantelmo A, Albini A, Presta M. Anti-FGF2 approaches as a strategy to compensate resistance to anti-VEGF therapy: long-pentraxin 3 as a novel antiangiogenic FGF2-antagonist. Eur. Cytokine Netw. 2009,.20: 225-34; IF= 2,064 263. Sogno I, Venè R, Ferrari N, De Censi A, Imperatori A, Noonan DM, Tosetti F, Albini A. Angioprevention with fenretinide: Targeting angiogenesis in prevention and therapeutic strategies. Crit Rev Oncol Hematol. 2009 Dec 22. IF=4,689 264. Tosetti F, Noonan DM, Albini A. Metabolic regulation and redox activity as mechanisms for angioprevention by dietary phytochemicals. Int J Cancer. 2009 Jun 23. IF= 4,926 265. Albini A, Mussi V, Parodi A, Ventura A, Principi E, Tegami S, Rocchia M, Francheschi E, Sogno I, Cammarota R, Finzi G, Sessa F, Noonan DM, Valbusa U. Interactions of singlewall carbon nanotubes with endothelial cells. Nanomedicine. 2010 Apr;6(2):277-88.. IF=4,882 266. Albini A, Pennesi G, Donatelli F, Cammarota R, De Flora S, Noonan DM.Cardiotoxicity of anticancer drugs: the need for cardio-oncology andcardio-oncological prevention. J Natl Cancer Inst. 2010 Jan 6;102(1):14-25. IF= 14,697 267. Albini A, Indraccolo S, Noonan DM, Pfeffer U. Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs. Clin ExpMetastasis. 2010 Apr 10. IF= 4,113 268. Cantelmo AR, Cammarota R, Noonan DM, Focaccetti C, Comoglio PM, Prat M, Albini A. Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth. Oncogene. 2010 Sep 23;29(38):5286-98. IF= 7,414 269. Albini A, Magnani E, Noonan DM. The tumor microenvironment: biology of a complex cellular and tissue society. Q J Nucl Med Mol Imaging. 2010 Jun;54(3):244-8. IF=2,640 270. Lopez NC, Valck C, Ramirez G, Rodriguez M, Ribeiro C, Orellana J, Maldonado I, Albini A, Anacona D, Lemus D, Aguilar L, Schwaeble W, Ferreira A. Antiangiogenic and antitumor effects of Trypanosoma cruzi Calreticulin. PLoS Negl Trop Dis. 2010 Jul 6;4(7):e730. IF=4,752 271. Bachmeier BE, Mirisola V, Romeo F, Generoso L, Esposito A, Dell'eva R, Blengio F, Killian PH, Albini A, Pfeffer U. Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin. Cell Physiol Biochem. 2010;26(3):471-82. IF=3,585 272. Albini A, Timar J. Genomics of metastatic progression. Clin Exp Metastasis. 2010 Aug 14. IF=4,113 273. Albini A, Noonan DM. The 'chemoinvasion' assay, 25 years and still going strong: the use of reconstituted basement membranes to study cell invasion and angiogenesis. Curr Opin Cell Biol. 2010 Oct; 22(5):677-89. IF= 13,54 274. Molteni LP, Rampinelli I, Cergnul M, Scaglietti U, Paino AM, Noonan DM, Bucci EO, Gottardi O, Albini A. Capecitabine in breast cancer: the issue of cardiotoxicity during fluoropyrimidine treatment. Breast J. 2010 Sep-Oct;16 Suppl 1:S45-8. IF=1,425 275. Cammarota R, Bertolini V, Pennesi G, Bucci EO, Gottardi O, Garlanda C, Laghi L, Barberis MC, Sessa F, Noonan DM, Albini A. The tumor microenvironment of colo-rectal cancer; stromal TLR-4 expression as a potential prognostic marker. J Transl Med. 2010 Nov 8;8(1):112. IF=3,508 276. Albini A, Cesana E, Noonan DM. Cancer Stem Cells and the Tumor Microenvironment: Soloist or Choral Singers? Curr Pharm Biotechnol. 2011 Feb 1;12(2):171-81 IF= 3,455 277. Albini A, Donatelli F, Sessa F, Noonan DM, Tosetti F. Re: Re: Neurocognitive Functioning in Adult Survivors of Childhood Noncentral Nervous System Cancers. JNCI, 2011. IF=14,697 278. Baldanzi G, Pietronave S, Locarno D, Merlin S, Porporato P, Chianale F, Filigheddu N, Cantelmo AR, Albini A, Graziani A, Prat M. Diacylglycerol kinases are essential for HGFdependent proliferation and motility of Kaposi's Sarcoma cells. Cancer Sci. 2011 Apr 7. IF= 3,846 279. Seo DW, Saxinger WC, Guedez L, Cantelmo AR, Albini A, Stetler-Stevenson WG. An integrin-binding N-terminal peptide region of TIMP-2 retains potent angio-inhibitory and antitumorigenic activity in vivo. Peptides. 2011 Aug 16. [Epub ahead of print]IF=2,654 280. Molteni LP, Cergnul M, Scaglietti U, Noonan DM, Bucci EO, Gottardi O, Albini A. Response to the letter to the editor. Breast J. 2011 Sep;17(5):566-7. IF=1,425 281. Albini A, Cesana E, Donatelli F, Cammarota R, Bucci EO, Baravelli M, Anzà C, Noonan DM. Cardio-oncology in targeting the HER receptor family: the puzzle of different cardiotoxicities of HER2 inhibitors. Future Cardiol. 2011 Sep;7(5):693-704. 282. Ferrari N, Tosetti F, De Flora S, Donatelli F, Sogno I, Noonan DM, Albini A.Dietderived phytochemicals: from cancer chemoprevention to cardio-oncological prevention. Curr Drug Targets. 2011 Dec 1;12(13):1909-24. IF=3,061 283. Albini A, Donatelli F, Noonan D, D'Elios MM, Prisco D. Bringing new players into the field: onco-pharmacovigilance in the era of cardio-oncology. Intern Emerg Med. 2012 Apr; 7 (2):99-101. IF=2,139 284. Albini A, Noonan DM. Angiopoietin2 and tie2: tied to lymphangiogenesis and lung metastasis. New perspectives in antimetastatic antiangiogenic therapy. J Natl Cancer Inst. 2012 Mar 21;104(6):429-31.. IF=14,697 285. Sogno I, Conti M, Consonni P, Noonan DM, Albini A. Surface-activated chemical ionization-electrospray ionization source improves biomarker discovery with mass spectrometry. Rapid Commun Mass Spectrom. 2012 May 30;26(10):1213-8. IF= 2,846 286. Tarantini L, Feola M, Albini A, Gori S, Foglietta J, Cicoira MA, Pulignano G. [Heart failure in women treated with adjuvant trastuzumab fro breast cancer]. G Ital Cardiol (Rome). 2012 May;13(5):54-62. 287. Solinas M, Massi P, Cantelmo A, Cattaneo M, Cammarota R, Bartolini D, Cinquina V, Valenti M, Vicentini L, Noonan D, Albini A, Parolaro D. Cannabidiol inhibits angiogenesis by multiple mechanisms. Br J Pharmacol. 2012 Nov;167(6):1218-31.. IF=4,409 288. Albini A, Tosetti F, Li VW, Noonan DM, Li WW. Cancer prevention by targeting angiogenesis. Nat Rev Clin Oncol. 2012 Sep;9(9):498-509. IF=11,963 289. Ruggiero L. Sogno I., Focaccetti C., Bartolini D., Magnani E., Principi E., Noonan DM., Albini A. Effects of Diet-Derived Molecules on the Tumor Microenvironment. Current Angiogenesis 2012 – Sept 1(3): 206-214. 290. Albini A, Donatelli F, Focaccetti C, D'Elios MM, Noonan DM. Renal dysfunction and increased risk of cardiotoxicity with trastuzumab therapy: a new challenge in cardio-oncology. Intern Emerg Med. 2012 Oct;7(5):399-401.. IF=2,139 291. Croci DO, Salatino M, Rubinstein N, Cerliani JP, Cavallin LE, Leung HJ, Ouyang J, Ilarregui JM, Toscano MA, Domaica CI, Croci MC, Shipp MA, Mesri EA, Albini A, Rabinovich GA. Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma. J Exp Med. 2012 Oct 22;209(11):19852000. IF=13,853 292. Puccio G, Brambilla P, Conti M, Bartolini D, Noonan D, Albini A Surface-activated chemical ionization-electrospray mass spectrometry in the analysis of urinary thiodiglycolic acid. Rapid Commun Mass Spectrom. 2013 Feb 15;27(3):476-80 IF=2,846 293. Bruno A, Focaccetti C, Pagani A, Imperatori AS, Spagnoletti M, Rotolo N, Cantelmo AR, Franzi F, Capella C, Ferlazzo G, Mortara L, Albini A, Noonan DM The proangiogenic phenotype of natural killer cells in patients with non-small cell lung cancer. Neoplasia 2013. Feb; 15: 133-42 IF=5.476. 294. Magnani E, Farnetti E, Nicoli D, Casali B, Savoldi L, Focaccetti C, Boni C, Albini A, Banzi M. Fluoropyrimidine toxicity in patients with dihydropyrimidine dehydrogenase splice site variant: the need for further revision of dose and schedule. Intern Emerg Med. 2013 Aug; 8(5): 417-23. IF=2,139 295. Amaro AA, Esposito AI, Mirisola V, Mehilli A, Rosano C, Noonan D, Albini A, Pfeffer U, Angelini G. Endocrine disruptor agent Nonyl phenol exerts an estrogen-like transcriptional activity on estrogen receptor positive breast cancer cells. Curr Med Chem. 2014; 21(5):630-40. IF=4,07 296. Bruno A, Pagani A, Magnani E, Rossi T, Noonan DM, Cantelmo AR, Albini A Inflammatory angiogenesis and the tumor microenvironment as targets for cancer therapy and prevention. Cancer Treat Res. 2014;159:401-26 297. Albini A, Rosano C, Angelini G, Amaro A, Esposito A, Noonan DM, Pfeffer U. Exogenous Hormonal Regulation in Breast Cancer Cells by Phytoestrogens and Endocrine Disruptors. Curr Med Chem. 2013 Nov 29. IF= 4,07 298. Dallaglio K, Bruno A, Cantelmo AR, Esposito AI, Ruggiero L, Orecchioni S, Calleri A, Bertolini F, Pfeffer U, Noonan DM, Albini A. PARADOXIC EFFECTS OF METFORMIN ON ENDOTHELIAL CELLS AND ANGIOGENESIS. Carcinogenesis. 2014 Jan 13. IF=5,635 299. Amaro A, Esposito AI, Gallina A, Nees M, Angelini G, Albini A, Pfeffer U. Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel. Cancer Metastasis Rev. 2014 Jan 30.IF=7,787 300. Bruno A., Ferlazzo G., Albini A., Noonan DG. A think tank on TINK/TANKs: Tumor Infiltrating Natural Killer cells and their role in angiogenesis and tumor progression - JNCI 2014 Submitted