introducing the specialistic degree in medicine and surgery
Transcript
introducing the specialistic degree in medicine and surgery
INTRODUCING THE SPECIALISTIC DEGREE IN MEDICINE AND SURGERY The New Didactical Curriculum of the Specialistic Degree in Medicine and Surgery, due to class of Specialistic Degrees 46/S, has been activated in the University of Studies of Pavia since academic year 2002/2003. It has been applied to the students matriculated from that year to nowadays, while other students are still following the old curriculum (the so-called XVIII ter-frame). The new curriculum, elaborated according to the decrees of Area of the Class of Specialistic Degrees in Medicine and Surgery, defines the formative objectives of the graduates which will have a knowledge of: • the scientifical basis and the theorical-practical preparation according to the directive 75/363/CEE to practice the medical profession; the methodology and culture needed to the practice of the permanent formation; a level of professional, decisional and operative authonomy derived from a formative course characterized by an olistic approach to medical problems, to healthy or unhealthy people also in relation with the chemical-physical, biological and social surrounding. • the essential theorical knowledges derived from the base sciences, in the prospective of the professional future application; the ability to notice and evaluate critically with a clinical point of view, and with a unitary vision, the etical and storical dimensions of medicine; the ability to communicate clearly and with humanity with the patient and his family; the ability of collaborating with the different professional figures in the sanitary group activities; the ability to apply the principles of sanitary economy in medical decisions,too; the ability to recognize sanitary problems of the community and to act with competence. ADMISSION TO THE DEGREE IN MEDICINE AND SURGERY In order to sign in for the Specialistic Degree in Medicine and Surgery, the candidates should have a High School Certificate or an equivalent foreign diploma. The number of students admitted is established according to the national programme and the disponibility of professors, didactical structures (classrooms, laboratories) and assistential structures, to do clinical rotations in the wards according to the raccomandations of the Advisory Committee on Medical Training of the European Union, applying parameters and directives predisposed by the Ateneo and the Department. The established number of matriculation in the first year is defined under the provision of the Law 264, August 1999 (about the access to university courses according to the law). The Academic Authorities have decided to matriculate for the academic year 2003/2004, 200 communitary and 15 foreign students. The access is determined by the results of the entry test, based on a merit graduation obtained by the score of the tests. The entry test is the same in all italian public Universities and takes place on the same date; it is given by the Minister of Education, of the University and Research, with a commission composed by experts thet have a ministerial assignment. The entry test consists of 80 multiple choice questions to solve, and only one out of five answers is correct. Topics: logic, general culture, biology, chemistry, physics and mathematics. The expiry date to sign in for the first year of Specialistic Degree is fixed unbreakably by the annual announcement of examination. FORMATIVE CREDITS The unit of measure of the work requests to the student to carry out formative activities according to the didactical Order for the graduation is the University Formative Credit (CFU). Every CFU is worth 25 hours of working activity of the student, including: - hours of lessons - hours of interactive didactical activities in laboratories, ward, outpatients departments, day hospital - hours of seminars - hours spent by the student in the other formative activities according to the Didactical Order hours of autonomous study needed to achieve proper formation. DIDACTICAL ORGANIZATION OF THE SPECIALISTIC DEGREE By the ministerial law about Determination of the Class of Specialistic Degrees (November 2000), the Course of Specialistic Degree in Medicine and Surgery provides 360 CFU, divided in six years of Course, comprehensive of 60 CFU in professionalizing apprenticeship, to get in formative activities aimed to the development of specific professional abilities. - - - - - The Specialistic Degree is articulated in 12 terms, 14 weeks each, aiming to a didactical progression from the knowledge of the base sciences, worked up in the first two years, to the medical and clinical methodology, of the sanitary organization on the territory, and of the etical and forensic aspects of medicine. Courses are articulated in modules according to the logic of didactical integration, which allows to achieve the interrelations existing between the contents of all the subjects. The total number of exams is 37 in the six years of Course; for the subjects lasting two terms is possible to undergo “in itinere” written examinations. If more than a teacher holds modules in the same integrated course, a course coordinator is elected, so the students can have a point of reference. The Professionalizing Internship (60 credits) has an important role as it gives the student the possibility to get more and more integrated in his future profession. Students are asked to do Internships - one per year – since the second year of Course, and each internship lasts one year. Student can attend wards such as Internal Medicine, General Surgery, Paediatrics, Obstetrics and Ginecology and so on. The Internship is a tutorial didactical activity which establishes the execution of practical activities under control of a Professor in charge, who plays the role of Tutor. Elective Activities (“Attività Didattica Elettiva”, ADE) chosen by the students are worth 15 CFU, and there aren’t examinations at the end. The global amount of credits for “Other” activities is 18 CFU: part of these are included in the integrated subjects Human Science, Clinical Methodology, English, Preventive Medicine, while 5 CFU are reserved to other linguistic knowledges, computer science, working stages. Final thesis is worth 15 CFU. TEACHING MODALITIES The didactical typologies of the subjects can be distinguished in: frontal lessons, seminars, interactive activities. Frontal Lesson means the development of a specific topic, defined by the formative curriculum according to the Study Course, made by a professor on the basis of a predefined calendar, and given to the students that are regularly matriculated. Seminar is a didactical activity with the same characteristics of the frontal lesson. Conferences on clinical-pathological topics, eventually established according to the clinical lessons, are recognized as seminar activity as well. Seminar activities can be interuniversitary and developed as videoconferences. The Interactive Activity is carried on by little groups of students, each of them with a teachertutor, who helps students to learn competences and behaviour. Learning is carried out by analysing problems through methodologic competences essential to be worked out, as practical activities, frequence in the wards, outpatients departments and research laboratories. EXAMINATION MODALITY To be admitted to examination, Students must attend at least 70% of frontal lessons and interactive – practical activities according to any formative plan. In case of subjects lasting two terms, this criterium is applied to each term. Every teacher establishes his way to check students’ frequency to his course. Credits corresponding to each subject are gained by students with the following methods: - passing the examination of curriculum subjects; obtaining the frequency signature by responsible professor in case of Elective Activities; in case of internships, obtaining the frequency signature released by professor and verifying abilities and attitudes in the examination of the different clinical subjects. In case Students do not comply with their frequency duties or fail their exams for more than an academic year, a request for the evaluation of their university career must be proposed to the Didactical Council of Medicine. Credits obtained before will be confirmed in case these are obsolete. PROPAEDEUTICITY AND BLOCKAGES To make sure a progressive and equilibrated culture growth of students, propaedeutic steps have been established as follows: The exam Chemistry and propaedeutic Biochemistry is propaedeutic for Biochemistry. The exam Histology and Embriology is propaedeutic for Human Anatomy. The Exams Physics, Biochemistry, and Human Anatomy are propaedeutic for Human Physiology. Physiology is propaedeutic for all clinical exams. Physiology and Human Pathology are propaedeutic for Laboratory Medicine. Medical and Surgical Semeiotics are propaedeutic for all clinical exams. PASSING FROM THE FIRST TO THE SECOND YEAR To matriculate to the second year, students must have gained 30 Credits, including credits given for examinations “in itinere” at the end of the classes; a maximum of 2,5 credits acquired according to the elective didactic activities, chosen between those offered from the first academic year, and a maximum of one credit acquired with the frequency and with one of the elective activities chosen by the students. Passing from the second to the third year: To matriculate to the third year students must have gained a total of 60 credits in the two years before, including elective and “others” activities credits, according to curricular rules (a maximum of 2,5 CFU for the ADE and 1 CFU for the “others” per academic year) and eventual examination in itinere that needs ability at the end of the Course. Passing from the third to the fourth year: To matriculate to the fourth year students must undergo all the exams of the first and second year and must have succeeded in the exam of General Pathology. Crossing from the fourth to the fifth year: All the Students regularly matriculated to the fourth year cross to the fifth year and can undergo the exams. Crossing from the fifth to the sixth year: Students regularly matriculated to the fifth year cross to the sixth year and can undergo the exams. Crossing from a year to the next is possible ony for students that have acquired the minimum number of CFU by september 30th, according to the rules. Students who haven’t obtained the regular frequency signature of each teacher and who weren’t able to gain the minimum number of CFU, are matriculated as “repeating”. Students that have attended the Courses for the number of years required by the curriculum and haven’t been gaining all the necessary credits to the Degree Exam are matriculated as “Out of Course”. CHECKING OUT LEARNING SKILLS Learning skills evaluation may be developed through formative evaluation and certificative evaluation. Formative evaluations (“idoneità”, abilities) are used to verify the efficacy of the learning process and also of the teaching about determined contents with an examination without mark. Certificative evaluations (profits exams) are instead aimed to verify and quantify with a mark the achievement of aims of subjects, certifying the level of individual learning of the Students. Exams may be done only at established times, called “exams sessions”. Evaluations can’t take place along with lessons time, neither with other activities, just to let the Students attend courses and related interactive – practical activities. There are three exams sessions per year: the first is in January-February, the second is in JuneJuly, the third is in September.It is possible to add one more session, identified by the Didactic Council in the month of December. The Last Exam consists of a discussion of the Thesis made by the candidate. ELECTIVE DIDACTIC ACTIVITY The Elective Didactic Activity (ADE) is about teaching-learning freely chosen by Students with the aim to personalize their own formation through a special development of the most interesting subjects. Electives can be proposed in terms of Internship, Monographic Courses and Seminars; once chosen, the frequency signature is mandatory to obtain credits: at the end of each event professors have to sign on the special booklet of the personalized formative courses. The Didactic Council yearly gives the list of the ADE about integrated subjects and the schedules that must not be the same of the schedules of the curriculum activities. In the six years of the Course, students must obtain 15 credits in total, spread in the years according with the plan of study, attending ADE, chosen between following typologies: Elective Internship: 1,5 Credits Monographic Course: 1 Credit Seminar: 0,25 Elective Internship: the Elective Internship requires a frequency of not more than 30 hours; it offers students the chance to develop many activities and can take place in research laboratories or in the Hospital. In both structures the intership activities must be useful to better Students’s knowledges in a specific structure, to develop cultural interests about their future job, apart from interactive activities, that are fundamental as well. To apply for internship, students must submit a written request to the professor in charge, along with a short curriculum vitae, to allow the selection of candidates in case the number of the requests are more than available places. Students can attend just one Elective Internship per year. Monographic Course: the Monographic Course gives the chance to deeply analyse the theorical topics explained in the Course and can take place through six frontal lessons, or with the ADE in small groups. Offered monographies change every year; students should follow at least one per year. It is necessary to obtain the final signature and/or a certificate, attending not less than 70% of lessons. Seminary: didactic activities with the same features of frontal lessons. Can be followed individually (students aren’t supposed to follow a complete cycle of lessons like monography), obtaining each time the related credits. “OTHER” ELECTIVE DIDACTIC ACTIVITIES The activities indicated as “Others” of the New Curriculum of the Specialistic Degree in Medicine and Surgery, consist in many activities that are expected to enrich students’ global culture and to help professional choices through a direct knowledge of working possibilities. “Other” Activities can be computer science (e.g. the ECDL computer’s driving licence), language courses, courses and seminars organized by University Colleges and approved by the Council of Faculty, working stages. According to the curriculum, students should achieve at least five credits through “Other” Activities; at the end they must gather the professor’s signature on their personal booklet. The “Other” activities that can be chosen along the six years of Medical Degree are: - Practical Course to the achievement of computer science: 1 credit (activated from the 1° to the 6° year). - Course of foreign language: 1 credit (activated from the 1° to the 6° year). - Monographic Course organized by the University Colleges: 1 credit (activated from the 1° to the 6° year). Orienting Course in the world of job: 1 credit (activated from the 4° to the 6° year) Seminars, frequency to congresses: 0,25 (activated from the 1° to the 6° year). The Didactic Council may approve credits for language courses followed in European Community’s States, on the basis of official certificates produced by University of Pavia itself but also by other structures. PROFESSIONALIZING INTERNSHIPS The professionalizing internships are particular activities that provide Students a specific professional knowledge in the field of Internal Medicine, General Surgery, Paediatrics, Obstetrics and Ginecology and other medical and surgical specialities. These activities must be carried out by Students themselves, under direct control of a tutor professor and must have a sort of autonomy, to make Students able to pratically apply their knowledge. The aim of professionalizing activities is to give to Students the ability of analyzing the signs and the symptoms, to match each others and make reasoning, diagnosis, and proposal of therapy. The 60 credits of professionalizing activities are obtained from the 2° year and are indicated on the study programme during the integrated courses, they are aquired passing subject’s examination that include the Professionalizing internships. THESIS-RELATED FORMATIVE ACTIVITIES Students are given 15 credits (365 hours) just to carry out the work on their Thesis, inside University’s structures, clinical structures or biology Institutes. These activities have been defined as “Degree Internship”. Students who want to attend a Degree Internship in a structure must submit a formal request to the Director, adding a curriculum vitae (a list of passed exams with marks together with a list of optional activities followed, stages in laboratories or clinic or whatever they did in their career). The Director of the structure, with other teachers, examines the request; if the student is allowed to enter the structure, the director nominates a Tutor, eventually indicated by the Students themselves, who has the responsability to control and certificate the activities carried on by Students. Degree Examination To be allowed to the Final Degree Examination Students must: - Have followed all the courses and have passed all the related exams; - have obtained a total of 360 CFU articulated in the six years of Course; - have delivered Student’s Office the following documents: a. request to the Rector of the University at least 30 days before the discussion of the Thesis; b. a copy of the Thesis at least 10 days before the discussion of the Thesis. The Degree Examination’s sessions take place in summer and autumn and there may be an extraordinary session according to the established calendar. GENERAL INFORMATION SOCRATES/ERASMUS PROGRAMME Official link of the european community website: http://europa.eu.int/comm/education/programmes/socrates/erasmus/erasmus_en.html Socrates is Europe’s education programme involving 31 countries and its main objective is to build up a Europe of knowledge, thus providing a better response to the major challenges of this new century: to promote lifelong learning, encourage access to education for everybody, and help people to acquire recognised qualifications and skills. In more specific terms, Socrates tries to promote language learning, and to encourage mobility and innovation. It supports the education of the least advantaged groups of people. It endeavours to counter social exclusion and underachievement at school. Erasmus is one of the eight actions of the European Community’s SOCRATES Programme, and it involves higher education. Since it was started in 1987, it has become stroger and stronger and 700 000 students have been able to take advantage of the mobility arrangements within Erasmus. Today, nearly all European universities take part in the project. Erasmus gives students the opportunity to study for a period of 3-12 months at a university or higher education establishment in another participating country. As a matter of principle, the time spent in the host country must be fully recognised by the home institution. The European credit transfer system (ECTS) is the major instrument to facilitate academic recognition of periods of study in partner establishments. It should be clear that there must be an agreement between the universities concerned before a person can take benefit from the Erasmus scheme. Socrates Erasmus director of the Faculty of Medicine is Professor Giovanni Ricevuti; he deals with partner Universities coordinators to ensure the feasibility of each student’s learning agremeement, and he takes care of the students themselves, making sure they have understood the aims of the programme. PARTNER UNIVERSITIES MALTA DANIMARCA FINLANDIA UNIVERSITY OF MALTA AARHUS UNIVERSITET SYDVAST POLYTECHNIC (YRKESHOGSKOLAN) UNIVERSITY OF TAMPERE FRANCIA UNIVERSITÉ CATHOLIQUE DE LILLE UNIVERSITÉ DE LA MEDITERRANEE AIX MARSEILLE UNIVERSITÉ JOSEPH FOURIER GRENOBLE I UNIVERSITÉ PAUL SABATIER- TOULOUSE III UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS VI) UNIVERSITÉ RENÉ DESCARTES (PARIS V) GERMANIA JOHANNES-GUTENBERG-UNIVERSITAT MAINZ RHEINISCHE FRIEDRICH-WILHELMS UNIV. BONN UNIVERSITAT LEIPZIG GRAN BRETAGNA UNIVERSITY OF LIVERPOOL PORTOGALLO UNIVERSIDADE DE COIMBRA UNIVERSIDADE DE LISBOA UNIVERSIDADE DO PORTO SLOVACCHIA UNIVERZITA KOMENSKEHO V BRATISLAVE (Comenius Faculty of Medicine) Univerzita Komenskeho v Bratislave Martin (Jessenius Faculty of Medicine) UNIVERZITA P.J. SAFARIKA V KOSICIACH SPAGNA UNIVERSIDAD COMPLUTENSE DE MADRID UNIVERSIDAD DE VALLADOLID UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE UNIVERSIDAD DE ZARAGOZA UNIVERSIDAD DE CATALUNYA UNIVERSIDAD DE BARCELONA UNGHERIA SVEZIA UNIVERSITY OF PECS GOTEBORGS UNIVERSITEIT CENTRO LINGUISTICO CENTRO LINGUISTICO is a interdepartmental center of services addressed to italian and foreign students and to the teaching and technical-administrative staff of the University of Pavia, with the aim to promote the learning of the foreign languages. It has three centers currently: Laboratories (Palazzo Centrale, Sforzesco Courtyard), Cravino Center (Faculty of Engineering, G1 classroom), Offices (Main Building, Teresiano Courtyard). The Center carries out many activities; in particular, it organizes courses of languages for Italian and foreign students in mobility; it is the center of examination for the certifications of English language of the University of Cambridge (PET, First Certificate, Proficiency) and for the Certification of Italian as Foreign Language of the “Università per Stranieri di Siena” (CILS); the service of auto-apprenticeship of the foreign languages and the Italian for foreigners. The CENTRO LINGUISTICO has many means of auto-apprenticeship: classrooms with listening facilities; a wide range of approximately 1000 courses with audio, video and cd-rom supports, about almost 47 various languages; around 350 videotapes of famous movies in their mothertongue. Technicians with Language Degree can help the students in the choice of learning means. Customers can moreover gather information and material on the main international certifications of foreign languages (apart from the ones mentioned before, the TOEFL for English language, the DELF/DALF for French language, the ZdaF/ZMP for German language, the DBE/DSE for Spanish language). Opening times: Laboratories monday-friday 9,00 a.m. - 6,00 p.m. Cravino Center: please call one of the number below or visit the website: http://www.unipv.it/cenling Useful numbers: Laboratories tel. and fax: +39 0382 984476 Offices tel. and fax +39 0382 984383 Cravino Center tel. +39 0382 985758 fax Center Cravino 0382 - 505760 CENTRO ORIENTAMENTO STUDENTI (C.OR.) This Center has the aim to follow and help students during their study career. The C.OR. organizes activities to support the students, from the last two years of the secondary School to the University, with particular attention to matriculation, first year of course and terminal phase leading to the job world. The center is located in via S. Agostino 8, phone 0039 0382 984218. Apart from the pre-university guidelines, the Center activity consists of two fields: - INTER-Universitary field - POST-Universitary field INTER-Universitary guideline C.OR. promotes activities to increase the effectiveness of the formative process and, at the same time, to make the student more aware of the choices and opportunities that are offered. To reach this goal, there are some kind of activities like: meetings with the freshers; promotion of propaedeutic courses; meetings with the Council of Faculty; services of “tutorato”, with the aim to support students during their academic career, helping them to face the most common problems (e.g. lessons and elective-optional activities attendance). The in use projects offered by Faculties are about one hundred and belong to three different typologies: • Informative “tutorato”: information on timetables, programs, courses and learning agreement choices. • Cognitive “tutorato”: organization of laboratories and seminars on specific topics, interactive activities in small groups (10-20 students), basic courses to approach new difficult subjects, choice of the method of study, simulation of written examination tests; • Psychological “tutorato”: it helps to solve problems in relational and learning field, using counseling (individual and in groups). POST-Universitary guideline C.OR. has a specific role in making students aware to choose and find their future job. The aim of the orienting program is to facilitate the work search, through meetings with important factories managers, post-graduated databases, information about stages, scholarship, courses. The University of Pavia, in collaboration with ISU, has created a postgraduated and researchers Database which may contain their CV, possibly to be linked to the major companies. Integration and servicing for disabled students (S.A.I.S.D.) Since 1999-2000, the University of Pavia has founded the “Servizio di Assistenza ed Integrazione Studenti Disabili” (S.A.I.S.D.), aimed to offer to the students with a disability an host service in order to integrate them in the university world. The Service coordinator and administrative manager, professor Sandro Meloni, with his team gives support to the students with disabilities. The Service operates in collaboration with the Service of Guideline of the I.S.U. in the attempt to realize for those students an integrated offer, with human and material resources. This Service offers various typologies of intervention for those students who matriculate as disabled: scholarships for students with 66% of invalidity; interpreters for deaf students; propedeutical courses of Italian Language of Signs LIS, in collaboration with Segretariato Italiano Studenti di Medicina; courses of orientation and mobility for blind students, in collaboration with Unione Italiana Ciechi; computer equipment for deaf students, as a support during the didactical activities; support to reach the lessons rooms inside the university structure; attendance during the hours of lesson;attendance at the university canteen; didactical material, recording and reading of lessons for blind students; computer equipments for blind and blind-deaf students. The S.A.I.S.D. has moreover disposed a braille handbook in order to teach those student how to use the computer equipment. Opening time: from monday to friday, 8,00 a.m. to noon. Deliveries Service Attendance and Integration of Disabled Students (S.A.I.S.D.): Address: Palazzo del Majno – Piazza Leonardo da Vinci Phone: +39 0382 984953 fax: 0382 984954 email: [email protected] Delegated of the Chancellor for the attendance to disabled people: prof. Sandro Meloni Phone +39 0382 987337 fax: 0382 528544 email: [email protected] Responsible for the Service Attendance and Integration of Disabled Students (S.A.I.S.D.): Sig. Enza Sciascia Phone +39 0382 984953 fax: 0382 984954 email: [email protected] BRIEF HISTORICAL INTRODUCTION: http://www.unipv.it/erasmus/incoming/index.html HIGHER EDUCATION IN ITALY: Link to the official website of the Ministero dell’Istruzione, dell’Università e della Ricerca about the rules of Higher Education. http://www.miur.it/guida/guide.htm PROGRAMMES OF THE COURSES 1st YEAR First year – 1st term INTEGRATED COURSE TOTAL CFU Physics (E) Physics 5 Chemistry and Propedeutical Biochemistry (E) Chemistry and Propedeutical Biochemistry Biochemistry 7 Medical – Scientific Metodology 1 (V) Statistics Hygiene Internal Medicine 5 Biology and Genetics (E) General Biology Molecular Genetics Human Genetics CytoGenetics 9 English (V) total 2 28 UNIT CFU 5 5 2 3 1 1 2,5 2 2,25 2,25 Second year – 1st term INTEGRATED COURSE Tot.CFU Biochemistry (E) Biochemistry Molecular Biology Cellular Biochemistry 11 Histology and Embriology (E) Histology Embriology Citology 9 Human Anatomy 1 (V) Human Anatomy 1 Topographic Anatomy 1 9 Elective Activities “Other” Activities TOTAL 2,5 1 32,5 Unit CFU 8 1 2 4,5 3 1,5 8 1 2nd YEAR 2 nd Year – 1st TERM CODE BIO/16 M-PSI/08 MED/02 MED/02 BIO/09 INTEGRATED COURSE Human Anatomy 2 (E) Human Anatomy 2 Topographic Anatomy 2 Human Sciences (V) Bioetics History of Medicine Psychology Human Physiology Nervous System Physiology Cellular Physiology Cardiovascular system Physiology Endocrine System Physiology Science of Nutrition TOTAL CFU CFU CFU Tot. C.I. Profes. 11 9 2 6 2 2 2 3 1,5 2,5 1,5 1,5 27 2ND YEAR – 2ND TERM Sett. Disc. BIO/09 MED/04 MED/04 MED/09 MED/09 MED/18 MED/18 MED/45 PSI/08 INTEGRATED COURSE CFU CFU CFU Tot. C.I. Profes. Human Physiology (E) REspiratory Physiology Muscle Physiology Digestive Apparatus Physiology Kidney Physiology 20 Immunology and General Pathology 1 (V) Immunology General Patology 8,5 Methodology and clinical Propaedeutics (V) Medical Propaedeutics Apprenticeship Surgical Propaedeutics Apprenticeship Nursing Sciences Psychology and doctor-patient relationship Elective Activities “Other” Activities TOTAL 7 3 2 2 3 5,5 3 1,5 1 1 1 1,5 1 2,5 1 29 3RD YEAR 3RD YEAR – 1ST TERM INTEGRATED COURSE Immunology and General Pathology 2 (E) General Pathology General physiopathology Pharmacology 1 (V) Pharmacology MicroBiology (E) MicroBiology Medical-surgical Semeiotics 1 Internal Medicine Apprenticeship General Surgery Apprenticeship Instrumental Semeiotics– Image based diagnosis TOTAL CFU CFU CFU Tot. 7 C.I. Profes. 4,5 2,5 5 5 7 7 5 2 2,5 0,5 24 3RD YEAR – 2nd TERM INTEGRATED COURSE Laboratory Medicine (E) Clinical Biochemistry Apprenticeship Molecular Biology Apprenticeship Clinical MicroBiology Apprenticeship Medical-surgical Semeiotics 2 (E) Internal Medicine Apprenticeship General Surgery Apprenticeship Instrumental Semeiotics– Image based diagnosis Diseases of the Endocrine System and of the Metabolism (E) Internal Medicine Apprenticeship Endocrinology Apprenticeship Medical-Scientific Methodology 2 (E) Hygiene and Epidemiology Medical Statistics Clinical Epidemiology Elective Activities Other activities TOTAL CFU CFU CFU Tot. 8 C.I. 3 Profes. 1 1,5 0,5 1,5 0,5 5 2 2,5 0,5 5,5 1 1 2,5 1 5 2 1,5 1,5 2,5 1 27 4th YEAR 4th YEAR – 1ST TERM INTEGRATED COURSES Diseases of the Cardiovascular Apparatus (E) Cardiology Apprenticeship Cardiosurgery Vascular surgery Pathologic Anatomy Pharmacology Diseases of the Respiratory system (E) Pneumology Apprenticeship Thoracic Surgery Apprenticeship Image-based diagnosis Pathologic Anatomy Pharmacology Diseases of the Digestive Apparatus (E) Gastroenterology Apprenticeship Digestive surgery Pathologic Anatomy Image-based diagnosis Pharmacology Diseases of the Blood (E) Hematology Apprenticeship Oncohematology Pathologic Anatomy TOTAL CODE CFU Tot. CFU C.I. CFU Profes. 8,5 MED/11 3,5 MED/23 MED/22 MED/08 BIO/14 1 1 0,5 0,5 2 8 MED/10 3,5 MED/21 1 MED/36 MED/08 BIO/14 0,5 0,5 0,5 2 8 MED/12 3,5 MED/18 MED/08 MED/36 BIO/14 1 0,5 0,5 0,5 2 6,5 MED/15 3 MED/15 MED/08 1 1,5 1 31 4th YEAR – 2nd TERM INTEGRATED COURSES Internal Medicine and General surgery (E) Internal Medicine Apprenticeship General Surgery Apprenticeship Diseases of the Immunitary System and Rheumatology (E) Clinical Immunology Apprenticeship Rheumatology Apprenticeship Diseases of the Kidney and of the Urinary Apparatus (E) Nephrology Apprenticeship Urology Apprenticeship Pathologic Anatomy Diseases of the Locomotor Apparatus (E) Orthopaedics Apprenticeship Physical Medicine and Rehabilitation Apprenticeship Image-based Diagnosis (E) Image – based diagnosis Apprenticeship CODE CFU Tot. CFU C.I. CFU Profes. 8 MED/09 2,5 1,5 MED/18 2,5 1,5 5,5 MED/09 1 MED/16 2,5 1 1 8 MED/14 3,5 MED/24 1 MED/08 0,5 2 1 5,5 MED/33 2,5 1 MED/34 1 1 MED/36 4,5 2,5 2 Elective Activites 2,5 Other Activities TOTAL 1 35 5th YEAR 5th YEAR – 1ST TERM INTEGRATED COURSE Diseases of The Sensory system (E) Oftalmology Apprenticeship Otolaringology Apprenticeship Audiology Apprenticeship Dentistry Maxillo-facial surgery Dermatology and Plastic surgery (E) Dermatology Apprenticeship Plastic surgery Apprenticeship Infectious diseases (E) Infectious diseases Apprenticeship Pharmacology Neurologic ssciences (E) Neurology Apprenticeship Neuroradiology Neurosurgery Pathologic Anatomy Pharmacology Preventive Medicine (E) Hygiene Sociology Sanitary Economy TOTAL SSD CFU CFU Tot. C.I. CFU Profes. 10,5 MED/30 2,5 MED/31 2,5 MED/32 1 1 1 0,5 MED/28 MED/29 1 1 5 MED/35 2,5 1 MED/19 MED/08 1 0,5 5 MED/17 2,5 2 BIO/14 0,5 9,5 MED/26 4,5 MED/26 MED/27 MED/08 BIO/14 0,5 1 0,5 0,5 2,5 5 MED/42 SPS/07 SECS-P/07 3,5 0,5 1 35 5TH YEAR 2ND TERM INTEGRATED COURSES Pharmacology 2 (E) Pharmacology Internal Medicine and Medical Therapeutics Psychiatry (E) Psychiatry Apprenticeship Pharmacology Public Medicine (E) Forensic Medicine Apprenticeship Work Medicine Apprenticeship Communitary Medicine Pathologic Anatomy (E) Pathologic Anatomy CODE CFU CFU CFU Tot. C.I. Profes. 5,5 BIO/14 MED/09 5 0,5 5 MED/25 3,5 1 BIO/14 0,5 9 MED/43 3,5 MED/44 2 MED/42 1 0,5 2 MED/08 6,5 6,5 Elective Activities 2,5 Other Activities TOTAL 1 29,5 6th YEAR 6th YEAR – 1ST TERM INTEGRATED COURSE CREDITS SUBJECTS INTERNAL MEDICINE 15 GENERAL SURGERY 14 GENERAL AND SPECISALISTIC PAEDIATRICS (E) 21 11 WORK MEDICINE (E) GYNAECOLOGY AND OBSTETRICS (E) 16 Internal Medicine Medical Therapeutics and Thermal Medicine Medical Genetics General surgery Oncological Surgery Paediatrics Preventive and Social Paediatrics Paediatric Surgery Paediatric Neuropsychiatry Work Medicine Industrial Hygiene Preventive Medicine and Psychotechnique of the Work Industrial Toxicology Gynaecology and Obstetrics Human Reproduction Physiopathology Gynaecologic Oncology Prenatal Age Medicine 6th YEAR – 1ST TERM INTEGRATED COURSE CREDIT SUBJECTS S INTERNAL MEDICINE (E) 15 MEDICAL-SURGICAL EMERGENCIES (E) 26 GENERAL SURGERY (E) 13 FORENSIC MEDICINE (E) 10 Internal Medicine Emergency Medicine Emergency Surgery Intensive Therapy Surgery Forensic Medicine Deontology and Medical Ethics Forensic Toxicology Forensic Psychopathology Social Medicine DESCRIPTION OF THE COURSES First year – 1st term INTEGRATED COURSE TOTAL CFU Physics (E) Physics 5 Chemistry and Propedeutical Biochemistry (E) Chemistry and Propedeutical Biochemistry Biochemistry 7 Medical – Scientific Metodology 1 (V) Statistics Hygiene Internal Medicine 5 Biology and Genetics (E) General Biology Molecular Genetics Human Genetics CytoGenetics 9 English (V) total 2 28 First Year – 2nd term INTEGRATED COURSE UNIT CFU 5 5 2 3 1 1 2,5 2 2,25 2,25 Tot.CFU Biochemistry (E) Biochemistry Molecular Biology Cellular Biochemistry 11 Histology and Embriology (E) Histology Embriology Citology 9 Human Anatomy 1 (V) Human Anatomy 1 Topographic Anatomy 1 9 Elective Activities “Other” Activities TOTAL 2,5 1 32,5 Unit CFU 8 1 2 4,5 3 1,5 8 1 FIRST YEAR – FIRST TERM Medical – Scientific Methodology Coordinator A. Marinoni Statistics M. Grassi, A. Marinoni Hygiene G. Pellissero Internal Medicine C. Balduini Unit: Teachers: Unit: Teachers: Unit: Teachers: AIMS: Students must learn fundamental notions of statistics, to be able biomedic field. By the end of the course, students must know methodology and statistic theories; they must be able to describe statistic inference (significativity – confidence ranges) to common comparing two groups and critically discussing the results. Recommended books to apply statistic techniques in general elements of research biomedic studies data applying problems of medical literature, Grassi M., Statistica in medicina: un approccio basato sulla verosimiglianza. McGraw-Hill, Milano, 1994. PHYSICS Coordinator Unit: Teachers: Interactive Exercitation Teachers: D. Scannicchio Physics D. Scannicchio A. Ottolenghi, E. Giroletti, L. Piazzi, P. Montagna AIMS: The course’s goal is to provide students a comprehension of physics phenomena applied to life sciences – to Medicine but also to Chemistry, Human Physiology, Biomedical Techniques and so on. Students must learn notions about energy, fluid mechanics, transport means in biological systems; they must be aware of onset and propagation of bioelectric phenomena and of the fundamental principles that are the bases of laboratory analyses and clinical diagnosis. Students have to learn basic elements of Mechanics, Thermology, Thermodynamics, Electricity, Ondulatory Phenomena. Recommended F. Borsa e D. Scannicchio, Fisica con applicazioni in Biologia e in Medicina, 2a books: edizione, UNICOPLI (1997). Biology and Genetics Coordinator Unit: Teachers: Unit: Teachers: Unit: Teachers: Unit: Teachers:: M. Scappaticci General Biology M. Scappaticci Human Genetics P. Maraschio Molecular Genetics G. Camerino CitoGenetics O. Zuffardi Aims: Students should learn the fundamental mechanisms regulating biologic processes in living organisms; they must know the modalities of gene transmission, their structure and the bases of mutation; know the different genic mapping in the human being; learn the risk of genetic diseases transmission and the prevention means; know the most relevant syndromes caused by chromosomic alterations. Recommended books Genetics, Peter J. Russell, Ed.Edises CHEMISTRY AND PROPEDEUTICAL BIOCHEMISTRY Coordinator M. Galliano, L. Minchiotti Unit: Chemistry and propedeutical Biochemistry Teachers: M. Galliano, L. Minchiotti Interactive exercitation A. Rossi, A. Bardoni Teachers AIMS: Students must learn fundamental chemical notions that are strictly necessary to understand the molecular point of view of all biologic phenomena. They must know the structure and the chemical – physical properties of living organisms elements. The course will deal with electronic configuration, inorganic compounds nomenclature, thermodynamic Chemistry and its concepts, chemical reactions and so on. Students must learn the features and classification of all the basic elements (glycosidic ligand, carbohydrates, amines and so on) and their main reactions. Recommended books Dickerson & Geis, Chimica materia e universo Raggi, Chimica Generale Binaglia, Giardina, Chimica e Propedeutica Biochimica Anastasia et al, Chimica di base per le scienze della vita - vol. 1 Hart, Chemistry organica Anastasia et al, Chimica di base per le scienze della vita - vol. 2 2nd TERM Biochemistry Coordinator Unit: Teachers: Unit: Teachers: Unit: Teachers: Interactive exercitation Teachers G. Cetta Biologic Chemistry G. Cetta , M. L. Speranza Molecular Biology G. Cetta Cellular Biochemistry M. Valli S. Rindi, R. Salvini, L. Visai, A. Forlino Aims: Students should acquire the knowledge of structure and functions of bio-molecules and aggregation of molecules. They should learn the structure and function of glucides, lipids, proteins, nucleic acids, and all the relations between those elements. They should also learn the interaction mechanisms between proteins and nucleic acids in the regulation of genic expression and the mechanism of action of principal hormones and most common vitamins. Students should also know the laboratory techniques mostly used to study the biochemical processes. Topics: Thermodynamics and bioenergetics. Proteins. Enzymes. Lipids. Biological membranes. Biosignals and regulation of the genic expression. Carbohydrates and Glicobiology. Nucleotides and nucleic acids. Metabolism (production of energy). Electrons transfer and oxydative phosphorylation of carbohydrates. Lipids biosynthesis. Amino-acides metabolism. DNA replication. RNA transcription and translation. Interactive activites: spectrometry; chromatography; electrophoresis; determination of enzymatic activity; recombinant DNA; restriction enzymes; DNA cloning, sequential DNA. Recommended books D. Nelson, M. cox “Principi di biochimica del Lehninger”, ed. 2002 Zanichelli D. Voet, J. Voet, C. Pratt “Fondamenti di Biohimica”, ed. 2001 Zanichelli Histology Coordinator Unit: Teachers: Unit: Teachers: Unit: Teachers: Interactive exercitation Teachers A. Calligaro Histology A. Calligaro Cytology A. Casasco Embriology M. Casasco A. Icaro Cornaglia Aims: Students should know how to identify tissues, cells and subcellular structures, describing their microscopic features and the functional aspects related to their specific morphologic organization. Through the study of gametogenesis, fecundation and embryonal development, students should know how to describe the modifications from primitive layers to organs. The integrated study of Histology and Embryology has the aim of teaching students how to identify and describe the subtle mechanisms of cellular differentiation, hystogenesis and embryogenesis. Recommended books Monesi – Istologia Ed. Piccin Alberts et al. – Biologia Molecolare della cellula Ed. Zanichelli Casasco – Citologia e Istologia Ed. La Goliardica pavese Casasco – Embriologia Generale Ed. La Goliardica Pavese Sadler – Embriologia Medica Ed.Masson Human Anatomy 1 Coordinator Unit: Teachers: Unit: Teachers: Interactive exercitation Teachers A. Tazzi Human Anatomy E. Gaeta Topographic Anatomy L. Baratta P. Micheletti Aims: Locomotor Apparatus: students should achieve a general idea of the skeleton, concerning the external and internal conformation of the bones, with detailed description of different bones. They should describe, referring to embryologic features, the different types of joints, skeletal muscles and annexa, their conformation and their relationship with other structures, in particular their macroscopical relation with tendons, in order to describe their function. Cardiocircolatory apparatus: students should know how to describe the micro and macroscopical structure of the heart, its configuration and its relationship with nearest structures, pointing out its anatomical features and its functions. They should describe the arterial system, how it works and the names of arteries, their internal structure, their morphology and the circulatory system. They should describe the venous system, the lymphatic system and the lymphatic glands. Recommended books: Tazzi, Gaeta, Anatomia Umana, Ed. Cirano Petra Kopf Mayer: Anatomia Umana – Atlante Ed. Edi Ermes Sobotta: Atlante di Anatomia MONOGRAPHIC COURSES – 1 C.F.U. ELECTIVE ACTIVITIES – 1ST YEAR Title of the Elective Activity Integrated course Responsible The use of energy among biological systems Chemistry - Prop. Bioch. Minchiotti L. Structure and functions of biologically interesting Chemistry - Prop. Bioch. molecules Tenni R. Citogenetics and prenatal diagnosis Biology & Genetics Zuffardi O. Citogenetics of instability syndromes Biology - Genetics Maraschio P. Internship Integrated course Responsible Internship in Biology: cell cultures Biology - Genetics Scappaticci M. Internship in Molecular Genetics Biology - Genetics Camerino G. Internship in CitoGenetics Internship in Molecular CitoGenetics Maraschio P. Zuffardi O. Marinoni A. Grassi M. Internship in Human Anatomy Internship in Biochemistry Biology -Genetics Biology - Genetics Metodologia Medico Scientifica Human Anatomy Biochemistry Internship in Histology Histology Calligaro A. Internship in Statistics Gaeta E. Valli M. Biochemistry of connettival matrix Biochemistry Rindi S. Histological techniques Histology Calligaro A. Anatomy of principal joints through new imagine techniques Human Anatomy Cusella M. G. Organogenesis of the heart and blood vessels Human Anatomy Gioglio L. Methods of study of proteins Biochemistry Galliano M. Methods of Molecular Biology to study nucleic acids Biochemistry Rossi A. Medical Instruments (Imaging) Physics Scannicchio D. INTERNSHIP 1,5 CFU OTHER ELECTIVE ACTIVITIES: ATTIVITA’ “ALTRE” : Monographic courses organized by Universitary Colleges 1 CFU ECDL Foreign language courses 1 CFU 1 CFU Objectives and aims of the 2nd year CODE INTEGRATED COURSE CFU CFU CFU Tot. C.I. Profes. 2 nd Year – 1st TERM BIO/16 M-PSI/08 MED/02 MED/02 BIO/09 CODE Human Anatomy 2 (E) Human Anatomy 2 Topographic Anatomy 2 11 Human Sciences (V) Bioethics History of Medicine Psychology 6 Human Physiology Nervous System Physiology Cellular Physiology Cardiovascular system Physiology Endocrine System Physiology Science of Nutrition TOTAL Integrated course 9 2 2 2 2 3 1,5 2,5 1,5 1,5 27 CFU CFU CFU Tot. C.I. Profes. 2 nd Year – 2nd TERM Human Physiology (E) Respiratory Physiology Muscle Physiology Digestive Apparatus Physiology Kidney Physiology 20 8,5 MED/04 Immunology and General Pathology 1 (V) Immunology MED/04 General Patology BIO/09 Metodologia e Propedeutica Clinica (V) 3 2 2 3 5,5 3 7 MED/09 MED/09 MED/18 MED/18 MED/45 PSI/08 Medical Propaedeutics Apprenticeship Surgical Propaedeutics Apprenticeship Nursing Sciences Psychology and doctor-patient relationship Attività Elettive Attività Altre TOTALE SEMESTRE 1,5 1 1 1 1,5 1 2,5 1 29 2nd year – 1st term Human Anatomy Coordinator Unit: Teachers: Unit: Teachers: Teachers didattica interattiva: A. Tazzi Human Anatomy A. Tazzi Topographic Anatomy L. Baratta P. Poggi, G. Cusella, L. Gioglio Objectives: Central Nervous System, encefalic nerves and organs of sense: to know in general terms the constitutive elements, the organogenesis and, approximately, the philogenesis of the central nervous system. To supply a macrocospic anatomical vision of the central nervous system. To describe the differences of the localization and anatomical constitution of the several types of meninges (dura madre, arachnoid, pia madre and spinal meninges), describing their functional aspects. To represent spatially the system of the cerebral ventricles in their relationships with the remaining encephalic structures and to describe the chorioid plexuses also in relation to the production of cerebrospinal liquid, outlining the functional aspects of the ventricular system. To illustrate the fundamental characteristics of the arterial vascular System and the venous-drainage of the brain, delineating the functional aspects of the vascularization of the SNC. To describe the structural and functional characteristics of the sensitive receptors and the peripheral nerves. To supply a macrocospic anatomical vision of the spinal medulla, describing its internal configuration, the general organization, the vascularization and the functional aspects; to define the structural and functional differences between grey substance and white substance; in particular to indicate the anatomical bases of the neurological phenomenon of the reflexes and the functions of the vegetative nervous system. To describe the macrocospic anatomy, the internal structure and the vascularization of the brain, indicating the functional aspects . To represent and to recognize the origin, the distribution and the function of the cranial nerves. To supply an anatomical outline of the visual system about its functional aspects, describing in their characteristics the several structures of the organ of the sight. To supply a general anatomical vision, topographical and functional, of the organ of the hearing in its components external, medium and internal, in relation to the acoustic and vestibular functions. To delineate the structure of the vegetative nervous system, to characterize localization of the ganglia and their relationships with the nearby structures. Splancnology: Splancnology has two aims: on one hand to teach the anatomical constitution of the several Systems and organs, according to the vision of the relationships with the surrounding organs (topographical anatomy gives a remarkable aid); on the other, to study the microscopical architecture of the several (to realize also through the study at the microscope) organs for being able to lead back the shape, the structure and the function. Peripheral nervous system: To know the origin, the constitution, the spacial relationships with the contiguous structures, the path and the distribution of the cranial and spinal nerves, and of preganglial and postganglial fibers. To characterize the modalities of formation and topographical localization of the nervous plexuses with the knowledge of the distribution of collaterals of the several plexuses. TOPICS: (epidermis, dermis, hairs, nails, sudoriparous glands, sebaceous glands) mamma: (feminine mamma, male mamma) glandular system. Spinal medulla: external conformation of the spinal medulla, internal structure of the spinal marrow, grey substance of the spinal marrow, white substance of the spinal marrow, central channel of the spinal marrow. Brain: medulla oblongata: external conformation of the medulla oblongata, internal structure of the medulla oblongata. Pons: external conformation of pons, internal structure of the pons. Cerebellum: external conformation of the cerebellum, subdivision of the cerebellum, internal structure of the cerebellum, constitution of the cerebellar pedunculus, afferent and efferent systems of the cerebellum, IV ventricle; Mesencephalon: external conformation of the mesencephalon, internal structure of the mesencephalon, cerebral aqueduct (of the Silvio), Diencephalon: hypothalamus, thalamus, epithalamus, III ventricle, telencephalon: external conformation of the cerebral hemispheres, constitution of the cerebral hemispheres, lateral ventricle, interhemispherical formations; Main sensitive and motility nervous ways: sensitive ways: spino-bulb-thalamus-cortical way, spino-thalamus-cortical way, trigeminale sensitive way, ways of the somatic sensitivity passing for the cerebellum, taste way, vestibular way, acoustic way, optical way, olfaction way; motility ways: pyramidal way, extrapyramidal way; Meninges: dura madre, arachnoid, pia madre, subarachnoidal space and cephal-rachidian liquid. Apparatus of the sight: eye, fibrous tunica of the eye, uvea, retina, crystalline lens, zonula ciliare, rooms of the eye and aqueous humour, vitreous humour) motility system of the eye: muscles of the eye, orbital bands, protecting apparatus of the eye: eyelashes, eyelids, congiuntiva, tear apparatus. Apparatus of the hearing and the equilibrium: external ear: auricular pavilion, external acoustic meatus, medium ear: cavity of the eardrum, mastoideo apparatus, auditive tuba, internal ear: bony labirynth, membranous labirynth, perilymph and endolymph. Circulatory apparatus Mediastinum Digestive Apparatus - Lodges of the neck and bands of the neck - Main topographical regions of the abdomen. Oral cavity - oral Vestibulum (Lips, Cheeks, Dental Arch) oral Cavity properly said (hard palate, soft palate, tongue, sublingual furrow) Pharynx: Structure of the pharynx (mucosa tunica of the pharynx, Pharyngo-basilar band, muscular tunica of the pharynx, peripharyngeal band). Esophagus (Structure of the esophagus) Stomach: Inner conformation of the stomach, structure of the stomach, tunica mucosa of the stomach, submucosa lyer of the stomach, muscular tunica of the stomach, sierosa tunica of the stomach. Little Bowel: Duodenum, mesentericum bowel, inner Conformation of the little bowel, Structure of the little bowel, mucosa tunica of the little bowel, submucosa layer of the little bowel, muscular tunica of the little bowel, sierosa tunica of the little bowel. Large Bowel: Blind intestine and vermicular appendix, Colon, rectum, Structure of the large bowel, Structure of the vermicular appendix, structure of the rectum. Large annexed glands to the digestive apparatus: Main salivary glands, Parotide, submandibolar gland, sublingual Gland, structure of the main salivary glands. Liver: tunicas of the liver, Structure of the liver. Biliary system: Biliary canaliculus, hepatic canal, cisticus and coledocus canals. Cholecystis. Pancreas: Structure of the pancreas. Respiratory apparatus: Nose - external Nose, nasal Cavity, tunica mucosa of the nasal fossa. Larynx: Cartilages of the larynx, Articulations and ligaments of the larynx, Articulations of the larynx, ligaments of the larynx, Muscles of the larynx, inner Conformation of the larynx, Tunica mucosa of the larynx. Trachea and broncus: Trachea, Broncus, Structure of the trachea and the broncus. Lungs: External conformation of lungs, Structure of lungs, Intrapulmonary part of the bronchial tree, pulmonary Parenchima. Pleura: Mediastinal cavity. Kidneys - inner Constitution of the kidney, Structure of the kidney, excretory Apparatus of the kidney, Structure of the excretory apparatus of the kidney. Urinary bladder, inner Conformation of the urinary bladder, Structure of the urinary blister. Feminine Urethra: Structure of the feminine urethra. Testicle - external Conformation and coverings of the testicle, inner Constitution of the testicle, Structure of the testicle. Spermatic ways: Spermatic cord. Male Urethra: Inner conformation of the urethra of male, Structure of the male urethra. Annexed glands to the male urethra: Prostate, bulb-uretral glands. Penis: Constitution of the penis. Ovary - Structure of the ovary. Uterine Trombae. Uterus: Inner conformation of the uterus, Structure of the uterus, Endometrium, Miometrium, Perimetrium. Vagina. Vulva: Great lips, Small lips, erectile organs of the vulva, Glands of vulva. Perineum - pelvic Diaphragm - uro-genital trigone- Superficial lay of the perineum. Peritoneum - omental borsa - Great omentum. Endocrine apparatus - Thyroid: Structure of the Thyroid; Parathyroid glands: Structure of the parathyroid glands; Adrenal glands: Structure of the adrenal glands. Paraganglion; hypophysis: Structure of the neurohypophysis and the adenohypophysis; Epiphysis: Structure of the epiphysis. Spinal nerves: cervical plexus(cutaneous and muscular collaterals of the cervical plexus). Brachial Plexus: collateral and terminal nerves of the brachial plexus. Intercostal N. Lumbar Plexus. Sacral Plexus: n. of the pelvic zone, N. of the free part of the inferior limb. Plexus pudendum. Coccigeum Plexus; Cranial Nerves: Olfactive N., optical N., oculomotor N., Troclear N., Trigeminal N., abducens N., facial N., acoustic N., glosso-pharingeal N., vagal N., accessory N., hypoglossal N.. Sympathetic: orthosympathetic, Parasympathetic (encephalic Parasympathetic, sacral Parasympathetic). Human Science: Coordinator Subject: Teachers: Subject: Teachers: Subject: Teachers: G. Ruberto Bioethics G. Ruberto History of Medicine P. Mazzarello Psychology P.L. Politi Objectives: The integrated course of Human Sciences, through History of Medicine, Bioethics and Clinical Psycology, has the aim to introduce the student to the past of the medicine in order to understand the present, to illustrate the process of transmission of the Western Countries’s medical knowledge in connection with the various cultures, to follow the evolution of the concept of disease in the scientific medicine, analyzing in detail some conceptual fundamental points that are the basis of the origins of the contemporary biomedicine (the birth of neuroscience, Genetics and microBiology and so on) and introducing the student to the knowledge of the advances of Molecular pathology and the biomedical technology; to introduce the student to the knowledge of the main methodologies of practical bioethical approach to clinical aspects, through the study and discussion of cases (ethical dilemmas), with particular reference to problems strictly related to the use of new technologies (genetic tests, use of staminal cells, regenerative medicine, problems connected with terminal diseases, ecc.) also through the analysis of laws and codes elaborated at national and international level; to introduce the student to main thematic about the relationship between doctor and patient, with particular reference to the aid relation, to the relationship with the patient in difficulty, the difficult patient and the terminal patient. Approximately the lessons will try to give particular prominence to a continuous comparison with the prejudgments, the dogmatic sideboards and the fideistical intellectual automatism that characterize the common perception of contemporary medicine. Human Physiology Coordinator: U. Ventura Subject: Physiology of the Nervous System Teacher: U. Ventura Subject: Cellular Physiology Teacher: R. Bottinelli Subject: Physiology of the Cardiovascular System Teacher: G. Gastaldi Subject: physiology of the endocrine system Teacher: G. Gastaldi Subject: science of nutrition Teacher G. Turconi Objectives: The integrated course of human Physiology is aimed to teach the student the vital processes that are carried out at cellular level when different groups of cells differentiate to form specific tissues and organs in the human species. By the end of the lessons of the integrated course, the student will have acquired fundamental knowledge about the function of the most important organs and apparatuses of the human body, their complex mutual relations and the control systems that regulate their activity. The course also deals with the human nutrition and the energetic metabolism and topics of sanitary physics. Topics: Cellular physiology: cellular functional morphology; movements of molecules through the membrane by diffusion and systems of transport. Homeostatic control systems: homeostasis at cellular level and of the total organism; chemical messengers and cellular receptors; postreceptorial events. Excitable tissues: Ionic equilibrium and cellular membrane voltage. Physiology of the nervous system: Characteristics and functions of the neurons; the property of the nervous fiber; the genesis of the nervous impulse; the conduction of the nervous impulse. The general principles of the sensory systems; the receptors of the somatosensitive system; conversion of the stimulus (generator voltage and receptor voltage) and coding of the electrical activity of the receptors. Adaptation of the receptors. The transmission of the nervous impulse among the neurons: electrical and chemical synapsis (inhibiting and excitating type). Inhibition and facilitation in the synapsis. Main neurotransmitters. Anatomo-functional organization of the spinal marrow. Function of the nervous system as one of the two control systems of the body functionality; main integrative activities like memory and language. The analysis of the nervous system and its functions will lead the student to understand that motorial and sensory function (reflected and voluntary type) are at the basis of the social life of man. Finally, the analysis of vegetative functions of the nervous system and of the multiple relations between nervous system and endocrine system will point out that the two control systems (nervous and endocrine), although through different modalities, can be considered as a whole control system, the so-called neuroendocríne system, responsible for the peculiar organization of the human body. Physiology of the cardiocircolatory system: blood: composition and chemical-physical characteristics of the plasma; plasmatic proteins and functions, figured elements of the blood and their functions; hematopoiesis, erythropoiesis and hemocateresis, haemostasis and coagulation. Cardiac function: described in its electrical and mechanical aspects and then analyzed in its possibilities to supply the different needs of the organism; function of the vascular system: illustrated in the basical principles (hemodynamics) and in the complex organization and regulation of the vessels of the systemic circulation and of the district circles that constitute it; Physiology of the endocrine system: endocrine function: illustrated in its peculiar aspect of one of the two control systems of multiple organic functions. In the description of the functions of the several endocrine glands, several modalities of endocrine control will be illustrated to the students. Science of nutrition: the functions of the aliments (energetic, plastic or structural, bioregolator of the organism), illustrated in relation to the biological and energetic requirements,in relationship with the principles of an healthy and corrected balanced nutrition IMMUNOLOGY AND PATHOLOGY – 1 Coordinator G. Gherardi Subject: Immunology Teachers: G. Gherardi Subject: General Pathology Teachers: G. Roveta, L.A. Stivala TOPICS: Immunology: to describe the experimental models of immunology analyzing the contribution to the location of the cells and molecules of the immune system, to the interpretation of the reaction of rejection of the transplants, to the understanding of the biology of the blood transfusions, to the fabrication and the use of the vaccine. To define the property of responsible molecules of the immunity: antibodies, TCR and proteins MHC. To define the responsible genetic mechanisms of the diversity and specificity of the immune answer. To illustrate the molecular bases of the specificity and the affinity of the antigen-antibody reactions. To illustrate the use of antigen-antibodies reactions in the diagnostical practice. To illustrate the procedures of monoclonal murine antibodies preparation and their diagnostic applications. To analyze the problems associated to the monoclonal murine antibodies use in therapy and the strategies of genetic engineering that obviate to these difficulties and allow the monoclonal antibodies use in therapy. To illustrate the sperimental phenomenon of the immunity tolerance and to analyze its importance in the Biology of the organ transplants. To illustrate the procedures that allow the typification of the tissues for their use in the transplants. To describe the genetics of the blood groups and their importance for the blood transfusions. To illustrate the effector mechanisms of the immune answer and in particular the system of complement. To illustrate genetic manipulations of the system of complement to eliminate the hyperacute rejection of xenotransplants and their impact for transplants of organ from animal to man. To describe the main categories of vaccines(killed, attenuated , in subunity and based on toxoids) and to illustrate their protecting property. To illustrate the impact of genetic engineering in the field of the vaccination. To describe the Koch’s phenomenon especially for the contribution that it has given to the understanding of the cellularmediated immunity. General Pathology: to Illustrate the concepts of lesion, pathology, pathologic process and pathologic state and to define the General Pathology discipline. Aetiology: To analyze the relative contribution of the genetic and environmental factors in the determination of human pathologies, including in the genetic factor also the phenomena of the penetrative capacity and the espressivity of the genes. To define the multifactorial ereditariety, citing some examples, and to distinguish the poligenic factors from the environmental factors. Considering the predisposition to become ill, to analyze system MHC and the pathology tied or associated to it. RECOMMENDED BOOK: CHOOSE ONE FROM THE LIST BELOW Le Basi patologiche delle malattie (Vol. I) – Robbins, Piccin , 2003 Guida allo studio della Patologia General- V. Vannini, La Goliardica pavese Kuby’s Immunology. Patologia e Fisiopatologia General W.H. Freeman Co. 4th ed., (2000) Cellular and Molecular Immunology. Abbas A.K.et al. . W.B. Saunders Co., 3rd ed., (1997). Immunology. Klein J. & Horejsi V. 2nd ed. Blackwell Scientific Publications., (1997) Essential Immunology. Roitt I. Blackwell Scientific Publications., 9th ed., (1997) Immunobiology (http://www.immunobiology.com) Janeway. CA, Jr., Walport M & Capra JD. Churchill Livingstone. 4th ed. (1999) Immunology. Roitt I., et al. 5th ed. Mosby Inc., (1998) Immunology. Elgert K.D. Wiley-Liss (1996) Methodology and Clinical Propedeutics Coordinator G. Ricevuti Subject: Medical Propedeutics Teachers: G. Ricevuti Subject: Surgical Propedeutics Teachers: L. Bonandrini Subject: Nursing Science Subject: Psicology and Relationship beetween doctor and patient Objectives: The integrated course of Clinical Methodology is aimed to teach the student the basic concepts of the characteristics of the medical action and the organization of the sanitary structures. The most Elementary procedures of the medical activity will be discussed and experienced: in particular the measurement of the arterial pressure, the manoeuvres of Basic Life Support, the puncture of a blood vessel. The student will have to assimilate the basic theorical knowledges and the elementary procedures for pharmacological, instrumental and technical management of surgical lesions and most common pathologies owning to the surgical area. The student will have to achieve the basic concepts for the psychical and psychological evaluation of the patient, in order to learn the behaviour of Patient and Doctor during the discovery and the evolution of the disease. Moreover they will be introduced to the principles of doctor-patientnurses relationship and the disease, and the team work, in order to learn the correct modalities to speak to the patients. The student moreover will be introduced to the concepts of the clinical medicine, owning to medical and surgical area. Students will be introduced to the role of the nurse in the doctor-patient-disease relationship, and they will experience the basic manoeuvres to approach the patient and to manage/move the patient in different phases of diseases, through the execution of elementary nursing manoeuvres. The course will consist of theorical frontal lessons and practical training, using computer means as well. ELECTIVE DIDACTICAL ACTIVITIES (ADE): II year Internships are carried out in the period indicated from the Teachers and it’s possible to follow only an Intership per year. In the first year students should at least acquire 2,5 CFU from ADE and 1 CFU from "other"activities. All the proposed Elective Activities can also be attended in the following years. Monographic Course 1 CFU Title of the Optional Course Integrated Course Teacher Deepening of the Anathomy of the Digestive Apparatus Human Anathomy Poggi P. Deepening of the Anathomy of the Tegumental Apparatus Human Anathomy Baratta L. Deepening of the Anathomy of the Urogenital Apparatus Human Anathomy Gaeta E. Deepening of the Anathomy of the Sensitive Organs: Eye Human Anathomy Tazzi A. Deepening of the Anathomy of the Sensitive Organs: Ear Human Anathomy Tazzi A. Internship 1,5 CFU Title of the Optional Course Internship of Human Anathomy Internship of Human Physiology Internship of Immunology Integrated Course Human Anathomy Human Physiology General Pathology, Immunology Teacher Tazzi A. Bottinelli R. E. Gherardi Elective Activities “Others” Monographic Course organized by university Colleges 1 CFU ECDL Additional courses of foreign language 1 CFU 1 CFU AIMS AND PROGRAMMES – 3RD YEAR 3RD YEAR – 1ST TERM INTEGRATED COURSE Immunology and General Pathology 2 (E) General Pathology General physiopathology Pharmacology 1 (V) Pharmacology MicroBiology (E) MicroBiology Medical-surgical Semeiotics 1 Internal Medicine Apprenticeship General Surgery Apprenticeship Instrumental Semeiotics– Image based diagnosis TOTAL CFU CFU CFU Tot. 7 C.I. Profes. 4,5 2,5 5 5 7 7 5 2 2,5 0,5 24 3RD YEAR – 2nd TERM INTEGRATED COURSE Laboratory Medicine (E) Clinical Biochemistry Apprenticeship Molecular Biology Apprenticeship Clinical MicroBiology Apprenticeship Medical-surgical Semeiotics 2 (E) Internal Medicine CFU CFU CFU Tot. 8 C.I. 3 Profes. 1 1,5 0,5 1,5 0,5 5 Apprenticeship General Surgery Apprenticeship Instrumental Semeiotics– Image based diagnosis Diseases of the Endocrine System and of the Metabolism (E) Internal Medicine Apprenticeship Endocrinology Apprenticeship Medical-Scientific Methodology 2 (E) Hygiene and Epidemiology Medical Statistics Clinical Epidemiology Elective Activities Other activities TOTAL 2 2,5 0,5 5,5 1 1 2,5 1 5 2 1,5 1,5 2,5 1 27 FIRST TERM Immunology and General Pathology 2 Coordinator V. Vannini Unit: General Physiology and Physiopathology Teachers: V. Vannini, G. Roveta Interactive activities Teachers L. Stivala AIMS: The course will provide students the fundamental notions to define risk indicators in preventive medicine, to approach laboratory medicine and to be able to set up a clinical reasoning. Students must learn the evaluation of genetic and environmental elements in the onset and evolution of diseases, and the analysis of pathologic agents and mechanisms, using Experimental Pathology notions. TOPICS: Ionized radiations and tissues radiosensitivity: flogogenous, mutagenous, teratogenous and cancerogenous effects. Exciting radiations: immediate and late effects and cancerogenous potential. Define biotransformation and differentiate detoxification and activation reactions, pointing the attention on induction phenomena. Know the mechanism turning xenobiotics into biologically active metabolites, analyzing from the molecular point of view the relationship between biologic activity and chemical reactivity. Analyze the relationship between the mutation of a single gene and metabolic errors, including genetic sensibility to drugs and natural substances. Identify different types of chromosomic anomalies (numeric and structural alteraltions) and multifactorial ereditariety (differentiating environmental and poligenic elements). Analyze monozigous twins to determine environmental and genetic elements. Describe structure-function of DNA and pathologies caused by its alteration. Using genetics consult, prenatal diagnosis and genetic sgreening, describe principal molecular biology techiniques and their application in diagnosing and therapy of some genetic pathologies. Analyze apoptosis, its onset and its difference from necrosis. Students must be able to use optical microscope by means of principal histochemical and cytochemical techniques. Analyze the differences between fibrosis and cyrrhosis in terms of cells proliferation. Analyze the differences between acute immediate and late inflammatory response, evaluating the role of chemical mediators (hystamine, prostaglandines, cytokines, and so on) and their features. Know the differences between chronic and acute inflammatory states, illustrating monocyte-monophage system and its role. Individuate the function of granulation tissue in relation to healing, regeneration, reconstruction and resolution phenomena. Analyze hyperplasia and neoplasia and the differences between benign and malignant evolution. Describe immunitary and inflammatory cells and their role in cancerous cells killing. Define cachexy and its mechanisms. Describe blood clots formation; atherosclerotic lesions – onset and features; Sanarelli and Schwartzman phenomena. Analyze homeostasis concept. Analyze the concept of stress and the psycho-neuro-endocrine-immunitary response leading to stress. Describe hypoxia; osmotic regulation; extracellular volume regulation; hyperosmolarity and hyposmolarity; natriemy and its role. Calculate plasmatic osmolarity and water amount in the body. Describe mechanisms that lead to oedema in congestive heart failure, pulmonary oedema, nephrosic syndrome, ascitis. Ilustrate mechanisms of potassium balance and its alterations. Recognize respiratory and metabolic acidbase unbalance evalualting pH, pCO2, HCO3- . Analyze the role of lungs, kidneys and liver in mantaining acid-base balance. Analyze from the physiopathologic point of view the notion of hypertension, considering risk factors and pathogenetic mechanisms. Analyze hypotension and metabolic-functional alterations. Describe shock: hypodynamic and hyperdynamic phases, hemodynamic response to shock and its effects on brain, heart, lung, kidney and digestive system, evaluating the possibility of irreversibility. Describe thermoregulation system, hyperthermia and hyperpirexia, hypothermia and metabolicfunctional effects from physiopathologic point of view. Recommended books Le Basi patologiche delle malattie(Vol. I) – Robbins, Piccin , 2003 Guida allo studio alla patologia General – V . Vannini, La Goliardica Pavese MICROBIOLOGY coordinator E. Romero Unit Microbiology Teachers E. Romero, L. Pagani, M. Debiaggi AIM: The course will provide the main notions and methodology to acquire fundamental basis of microbiology, to be able to correlate composition, structure and physiology of microrganisms with onset and evolution of infectious diseases; to apply the knowledge of microrganisms biology to the choice of correct therapy and antibiotic drugs, and to prevention strategies; to gain diagnostic methodology to approach infectious diseases; to learn the role played by each microrganism in human pathology; to understand infections epidemiology. Recommended I. Covelli, L. Spandrio, M. Zatti, C. Lechi, E. Nani: Medicina di Laboratorio, Ed. books Sorbona – Milano J.F.Zilva, P.R., Pannall, P.D. Mayne: Biochemistry Clinica in diagnosi e terapia, Ed. Soc. Ed. Universo – Roma J. Baynes, M. H. Dominikzac: Medical Biochemistry, ed. Mosby, London L. Thomas: Clinical Laboratory Diagnostics, ed TH Books, Frankfurt R. Cevenini: MicroBiology Clinica Ed. Piccin A.M. Molina: MicroBiology Clinica Ed Utet PHARMACOLOGY 1 Coordinator Unit Teachers Unit Teachers P.Richelmi General Pharmacology P.Richelmi M.P.Vairetti Cellular and Molecular Pharmacology A.Bianchi A.Di Nucci AIMS Students must learn the fundamental principles of biological drug effests, under the different points of views: pharmacodynamic (mechanism of action, drug-receptor interaction, receptorial theories), pharmacokinetic (diffusion of drugs through biologic membranes, absorption, delivery and escretion), pharmacometabolism (biotransformation of drugs, enzimatic inhibition and induction), pharmacometric (evaluation and measure of pharmacologic effect) and toxicologic (mechanism and features of drug toxicity; side effects). TOPICS: Drugs: nature, origin, features; pharmacologic experimentation; drugs absorption; drug delivery; drug metabolism; enzimatic induction and inhibition; excretion; general toxicology. Pharmacokinetics: general principles, absorption and delivery, interactions; notions on antibiotic therapy; mechanism of drugs action; structure-action relationships, drug-receptor interaction, receptorial theories; agonism-antagonism; drug tolerance; not conventional therapies; pharmacogenetics; drug monitoring. RECOMMENDED Goodman & Gilman’s : Le Basi Farmacologiche della Terapia, 8a edizione, BOOKS Zanichelli. Fulgraff G: Farmacologia General e Clinica, Edizioni Mediche Scientifiche Internazionali. M.J. Neal: Farmacologia medica in uno sguardo, 1999 La Goliardica Pavese. Richelmi e Berté : Farmacologia General, 1996, La Goliardica Pavese. B:G: Katzung: Farmacologia General e Clinica Ed. Piccin 2 ND TERM MEDICAL AND SURGICAL SEMEIOTICS Coordinator S. Tinozzi Unit: Medical semeiotics Teachers: E. Marchesi Unit: Surgical semeiotics Teachers S. Tinozzi, C. Bianchi L. Bernardi, G. Ricevuti, G. Gamba,S. Perlini, R. Invernizzi, P. Gobbi, P. Noris, F. Recusani, C. Falcone, M. Previtali, E. Vanoli, A. Dal Canton, C. Interactive activities Esposito, C. Libetta, C. Bianchi, G. Volpato, P. Colombo, R. Moia, M. Teachers Cugnasca, G. Fraipont, R. Alessiani, A. La Rosa, F.Calliada, AIMS: At the end of the course the student should know the general principles to carry out a medical examination and apply metodologies and tecniques of anamnesis, medical examination, instrumental exams; know the processes of diagnostic classification (tassonometry, classifications, identifications of the case); know the principles of metodology of scientific research in clinics and on general population, and the means of epidemiological approach; know the prevention and the risk factors for infectious or not infectious diseases; be able to read and to do a critical interpretation of medical literature; be able to communicate with the patient and his relatives, and with the members of the medical equipe. LABORATORY MEDICINE Coordinator: R. Moratti Unit: Clinical Biochemistry Teachers: R. Moratti Unit: Molecular Diagnostic Methodology Teachers: G. Merlini Unit: Clinical MicroBiology Teachers: L. Pagani AIMS: Students must learn most important laboratory analyses, their physiopathologic bases, their interpretation (related to measure factors and biologic variability); they must learn how to evaluate laboratory tests reliability, and to evaluate the results in relation to the patient’s pathologic conditions; to programme routine and specialistic exams both in ward and outpatients department; they must know how to correctly interpretate analyses and how to use them in screening, diagnosis, staging and therapy of diseases; they must gain the ability to choose the most appropriate exams in relation to diagnostic hypothesis, and have notions of quality control and sensibility-specificity. They should know the diagnostic potential of new technologies such as proteomics, pharmacogenomics, cell-sorting and micro-arrays. They must know microbiologic diagnostic principles, executive protocols rules, and appropriate diagnosing protocols to identify organs and systems infections and to interpretate results of laboratory tests. They must know the relation between pathological frames and possible etiologic agents. TOPICS: Clinical Biochemistry: total plasmaproteins and specific sieroproteins; lipids and lipoproteic classes, structures, atherosclerotic risk parameters; enzimatic activities in the serum: rating methods, organ and tissue profiles; parameters to determinate hepatic and renal functionality; most recent markers of myocardial damage in order to do a differential diagnosis of acute coronary syndromes; glycemic homeostasis: its regulation, tests and study methods; uric acid and notions of plasmatic aminoacids and aminoacid-related pathologies; hydroelectric and acid-base balance; normal and pathologic hemoglobins: structure and diagnostic elements; bilirubine and porphirine; sideremy, cupremy and clinically interesting oligoelements; notions on coagulation and hemorrhage risk tests; laboratory monitoring of thrombotic risk; urine analysis; Old and new hemocromocytometric test; hypophysis study methods, tyroid profile; surrenal cortex and corticosteroids synthesis; gonadotropins and ovarian-testis function; laboratory tests and diagnosis in pregnancy; neoplastic markers; autoimmunity laboratory diagnosis; drugs monitoring and notions of pharmacogenomics. Molecular Diagnostic Metodology: preanalytic step, means to take biologic liquids; analytic and biological variability; range values, refertation; errors measure, security quality in the laboratory; diagnostic logic path of laboratory medicine: predictive values, critical differences, decisional levels; electrophoretic methods and bidimensional electrophoresis, and study of biologic liquids proteins; clinical applications of capillar electrophoresis; diagnostic application of spectrometry and proteomics; immunochemical quali-quantitative methods; different study methods in blood cells: cytofluorimetry and cell-sorting; study and clinical importance of apoptosis; nucleic acid analysis technique and diagnostic application; "microchip technology" and potential diagnostic applications. Clinical MicroBiology: principles of microbiologic diagnosis; gathering and transportation of pathologic materials; direct examination and coltures; microbial macromolecules findings and sierologic diagnosis; microbiology of the infections of respiratory ways, ear, eye, genito-urinary apparatus, digestive system, foetus and newborn. Microbiology of the infections of cardiovascular apparatus, central nervous system, skin, bones, junctures; microbiology of nosocomial infections. Role of microbiology in control and prevention.. RECOMMENDED I. Covelli, L. Spandrio, M. Zatti, C. Lechi, E. Nani: Medicina di Laboratorio, Ed. BOOKS Sorbona – Milano J.F.Zilva, P.R., Pannall, P.D. Mayne: Biochemistry Clinica in diagnosi e terapia, Ed. Soc. Ed. Universo – Roma J. Baynes, M. H. Dominikzac: Medical Biochemistry, ed. Mosby, London L. Thomas: Clinical Laboratory Diagnostics, ed TH Books, Frankfurt R. Cevenini: MicroBiology Clinica Ed. Piccin A.M. Molina: MicroBiology Clinica Ed Utet MEDICAL-SCIENTIFIC METODOLOGY Coordinator: Unit: Teachers: Unit: Teachers: Unit: Teachers: A. Marinoni Clinical Epidemiology A. Marinoni Medical Statistics M. Grassi Epidemiology and Hygiene M. T. Tenconi, F. Sottocornola Objectives: At the end of the course the student should know the general principles for execution of a medical exam and apply metodologies and tecniques of anamnesis, objective exam, instrumental exams; know the processes of diagnostic classification (tassonometry, classifications, identifications of the case); know the principles of methodology of scientific research in clinics and in the general population, means of epidemiological approch; know the protectional and risk factors for infective or not infective disease; be able to read and to do a critical interpretation of medical literature; be able to talk to the patient and his relatives, and to the members of the assistential equipe. Topics: Classification of the researches in medicine; the casual evaluation in the observational and experimental studies; the logic of the diagnostic reasoning; exercitation on: interpretation and validation of the diagnostic data; the theorical basis of clinical experimentation and the scientific method; organization and planning of a experimentation: the programmation of the protocol; exercitation: how to read a scientific article; controls, blindness and placebo (A. Marinoni); exercitation on some examples; randomization (A. Marinoni); exercitation on some problems; drawings of sperimental studies (A. Marinoni); reading an article; discussions of a research (A. Marinoni); exercitation on pratical problems; drop-out and deviations from protocol. Analysis of data; programmed and explicative approch; evidence-based medicine. DISEASES OF THE ENDOCRINE SYSTEM AND OF METABOLISM Coordinator: L. Chiovato Module: Endocrinology Teachers: L. Chiovato Module: Metabolic diseases Teachers: D. Geroldi, B. Solerte Interactive activities teacher: F. Magri Objectives: Endocrinology: The Course aim is to provide Students the basic notions of physiopathology and clinics of endocrine diseases. The systematic approach to main endocrine diseases is dealt from the point of view of internal medicine, with a particular attention on multidisciplinarity of endocrine diseases. Interesting clinical cases are discussed along with virtual ones, and there is also the possibility of pratical activity in outpatients department. • Topics: Endocrinology: Hypothalamic disease. Insipid diabete; global and selective hypopithuitarisms; hypofisis releasing and not releasing tumors; thyreotossicosis: nosography, clinics, diagnosis and therapy; hypothyroidism: nosography, clinics, diagnosis and theraphy; nodular diseases of thyroid; hypoparathyroidism and hyperparathyroidism; acute and chronic hyposurrenalism; Cushing syndrome; (mentioned) male and female hypogonadism. Diseases of metabolism goals: To provide students the physiopathologic knowledge of diseases of the metabolism; to develop a methodology for their clinical recognition: to provide the elements for an integrated view of metabolic diseases. • Topics: physiopathology of glicoregulation; diabetes mellitus and cronical-acute related complications; hypoglicemia. Obesity; general physiopathology of purine metabolism; gout; hemocromathosis; general physiopathology of lipid metabolism; lipidosis; endocrine pathologies-related metabolic alterations. Recommended Harrison’s Principles of Internal Medicine, Braunwald et al. (eds), McGraw-Hill, bibliography: 2001. Endocrinology and Metabolism, eds. McGraw-Hill Clinical Medicine Series, Pinchera et al. (Eds.), McGraw-Hill, 2001. Basic & Clinical Endocrinology, Greenspan et al. (Eds.), Appleton & Lange, 2000 Cecil "Trattato di Medicina Interna" 3RD YEAR’S OPTIONAL ACTIVITES (ATTIVITÀ di DIDATTICA OPZIONALE: A.D.E.) Monographic corse 1 CFU Title of the optional course Biology of antimicrobic drugs Integrated corse Microbiology Responsible L. Pagani Molecular Microbiologic Diagnostics Microbiology M. Debiaggi Biologic defense: from the biology to clinic and Semeiotics and Clinical methodology. G. Ricevuti pathology Physiopathologic circulatory widener Surgical and medical semeiotics C. Falcone Sanitary Demographic Issues Surgical and medical semeiotics Applicated Clinical Ethics Surgical and medical semeiotics Microscopic observation Training in General Immunology and General Pathology Pathology F Sottocornola G. Ruberto V. Tannini Internship 1,5 CFU Title of the Optional Corse Integrated Corse Responsible Generic Pathology Internship Immunology and Generic Pathology V. Vannini Medical Genetics Internship Medical Scientific Methodology Internship Genetic and Biology C. Danesino Endocrinal System and Metabolism L. Chiovato Diseases Medical Scientific Methodology A. Marinoni Microbiology Internship Microbiology L. Pagani Medical Semeiotics Internship Medical and Surgicalal Semeiotics E. Marchesi Surgical semeiotics Internship Medical and Surgicalal Semeiotics S. Tinozzi Laboratory Medicine Internship Laboratory Medicine R. Moratti Endocrinology Internship Programs and Objectives of IV Year 4th YEAR – 1ST TERM INTEGRATED COURSES Diseases of the Cardiovascular Apparatus (E) Cardiology Apprenticeship Cardiosurgery Vascular surgery Pathologic Anatomy Pharmacology Diseases of the Respiratory system (E) Pneumology Apprenticeship Thoracic Surgery Apprenticeship Image-based diagnosis Pathologic Anatomy Pharmacology Diseases of the Digestive Apparatus (E) Gastroenterology Apprenticeship Digestive surgery Pathologic Anatomy Image-based diagnosis Pharmacology Diseases of the Blood (E) Hematology Apprenticeship Oncohematology Pathologic Anatomy TOTAL CODE CFU Tot. CFU C.I. CFU Profes. 8,5 MED/11 3,5 MED/23 MED/22 MED/08 BIO/14 1 1 0,5 0,5 2 8 MED/10 3,5 2 MED/21 1 MED/36 MED/08 BIO/14 0,5 0,5 0,5 8 MED/12 3,5 2 MED/18 MED/08 MED/36 BIO/14 1 0,5 0,5 0,5 6,5 MED/15 3 MED/15 MED/08 1 1,5 1 31 4th YEAR – 2nd TERM INTEGRATED COURSES Internal Medicine and General surgery (E) Internal Medicine Apprenticeship General Surgery Apprenticeship Diseases of the Immunitary System and Rheumatology (E) Clinical Immunolgoy Apprenticeship CODE CFU Tot. CFU C.I. CFU Profes. 8 MED/09 2,5 MED/18 2,5 1,5 1,5 5,5 MED/09 1 1 Rheumatology Apprenticeship Diseases of the Kidney and of the Urinary Apparatus (E) Nephrology Apprenticeship Urology Apprenticeship Pathologic Anatomy Diseases of the Locomotor Apparatus (E) Orthopaedics Apprenticeship Physical Medicine and Rehabilitation Apprenticeship Image-based Diagnosis (E) Image – based diagnosis Apprenticeship MED/16 2,5 1 8 MED/14 3,5 2 MED/24 1 MED/08 0,5 1 5,5 MED/33 2,5 MED/34 1 1 1 MED/36 4,5 2,5 2 Elective Activites 2,5 Other Activities TOTAL 1 35 DISEASES OF THE CARDIOVASCULAR APPARATUS Coordinator M. Vigano Module Cardiology Teachers P. Schwartz, F. Recusani, S. Priori, C. Falcone Interactive activities teachers E. Vanoli Module: Cardiosurgery Teachers M. Viganò, A.M. D'Armini Module: Vascular Surgery Teachers: A. Odero Module: Patological Anatomy Teachers: E. Silini, R. Scelsi Module: Pharmacology Teachers: G.M. Frigo OBJECTIVES: At the end of the course students will have to know how: • to do a clinical examination of the patient with formulation of diagnostic suspicion; • which are the most common instrumental examinations to support clinical examination and their diagnostic meaning; • for each clinical frame the student should know: what it is (definition); how much is important (epidemiology); why and how it happens (etiology, physiopathology); which are the clinical and instrumental features and how the diagnosis is made; to what it may lead (natural history, complications); what to do and where (notes of therapy, domiciliar and hospital therapy); possible phases of the disease needing urgent participations (how to recognize emergencies, how to deal with them); • which are the stages leading to surgical solutions; • which are the fundamental methodologies for the open heart operations (extra corporeal circulation, myocardial protection, hypothermia); • fundamental knowledge for the management of the patient with lung and heart transplant; fundamental knowledge for the management of the respiratory insufficiency TOPICS: CARDIOLOGY: • Endocarditis (acute articular rheumatism and rheumatic endocarditis, bacterial endocarditis) • Acquired valvular pathologies (mitralic valvulopaties, aortic valvulopaties, the secondary pulmonary hypertension, tricuspidal insufficiency). Other valvular pathologies (prolapses of the mitral valve). Pathologies concerning the left atrium (endoatrial thrombosis, mixoma); • Myocardiopathies (primitive and secondary dilatative myocardiopathies, secondary and primitive hypertrophic myocardiopathies, obstructive hypertrophic myocardiopathies, signs of restrictive myocardiopathies), • Mechanisms of heart compensation; • Heart failure (acute pulmonary oedema, chronic venous system congestion, cardiogenic shock: differential diagnosis with other kinds of shock); • Acute and chronic pericarditis (benign acute pericarditis, heart tamponation, chronic pericarditis with or without constriction); • Ischemic cardiopathy (atherosclerosis of the coronaries, acute and chronical coronary syndromes: myocardium infarction and its acute and chronic complicances, unstable angina pectoris, stable chronic angina); • Sudden death; • Long QT Syndrome; • Tachicardic arrhythmies (extrasistolia, supraventricular parossistic tachycardias, atrial fibrillation, ventricular tachycardias, ventricular fibrillation), • Bradicardic arrhythmies (atrioventricular blocks, MAS syndrome: other syncopes); • Preexcitation ventricular syndrome (W-P-W); • Main congenital cardiopathies (the valvular aortic stenosis and the cohartation, the isolated pulmonary stenosis, the shunts, the defects of the septum, the overload of pulmonary volume, the pulmonary hypertension, the Eisenmenger, the cyanosis, signals on Fallot’s disease); • Acute pulmonary heart (pulmonary niggle) and signals on the chronic pulmonary heart. CARDIOSURGERY: • Extra corporeal circulation; • Myocardial protection; • Surgical valvular pathologies and main protesic models; • surgery of the coronaries and the complicances • Heart and heart-lungs transplantation • Surgical treatment of the main congenital cardiopathies. VASCULAR SURGERY: • Chronic obstructive arteriopaties of the inferior limbs • Obstructive visceral vessels pathology • Acute ischaemia of the limbs (arterial emboli, arterial thromboses, traumas of the arteries); • Aneurisms (of the thoracic aorta, of the abdominal aorta, the visceral arteries, of peripheral vessels) • Cerebral vascular insufficiency • Varicosis of the inferior limbs (primitive and secondary) • Inflammatory chronic angiopathies (Buerger’s disease, Takayasu’s disease, Horton’s disease) • Venous thrombosis, post -phlebitic syndrome • Vascular pathologies-related oedemas of the limbs (phleboedema, lymphoedema). Recommended books Vascular Surgery and Angiology: Cardiology: Cardiosurgery: Elementi di Patologia e Chirurgia Vascolare. P. Fiorani, GR Pistolese, C. Spartera, V. Faraglia. Ed. Antonio Delfino, Roma. Manuale di Cardiologia. Di G. Specchia Medicina interna. Di Rugarli Il cuore: arterie e vene. Di Will Hurts. Ed Mc Graw Hill MALATTIE DEL CUORE E DEI VASI. Vol. I e II. Di S. Dalla Volta. Ed. Mc Graw Hill La chirurgie des aneurysmes de l’aorte. Dubost – Guilmet. Masson 1970. Cardiac surgery. Kirklin – Baratt Boyes. Churchill Livingstone 1988. Surgical treatment of congenital heart diseaseS. Hallman – Cooley. Nouveau traitè de technique chirurgicale. Coeur Gros vaisseaux pericarde Blondeau – Herry. Masson 1970. TRANSPLANTATION D’ORGANES. Carpentier –Farge. Flammarion 1992. DISEASES OF THE RESPIRATORY APPARATUS Coordinator: Module: Teachers: Module: Teachers: Module: Teachers: Module: Teachers: E. Pozzi Respiratory Apparatus Diseases E. Pozzi, V. Peona, F. Meloni Thoracic Surgery G. Volpato Patological Anatomy E. Silini, R. Scelsi Pharmacology G.M. Frigo OBJECTIVES: At the end of the course students will have to know how: • to do a clinical examination of the patient with formulation of diagnostic suspicion; • which are the most common instrumental examinations to support clinical examination and their diagnostic meaning; • for each clinical frame the student should know: what it is (definition); how much is important (epidemiology); why and how it happens (etiology, physiopathology); which are the clinical and instrumental features and how the diagnosis is made; to what it may lead (natural history, complications); what to do and where (notes of therapy, domiciliar and hospital therapy); possible phases of the disease needing urgent participations (how to recognize emergencies, how to deal with them); • which are the stages leading to surgical solutions; • which are the fundamental methodologies for the open heart operations (extra corporeal circulation, myocardial protection, hypothermia); • fundamental knowledge for the management of the patient with lung and heart transplant; fundamental knowledge for the management of the respiratory insufficiency DISEASES OF RESPIRATORY APPARATUS: • Pneumonias • Acute bronchitis • Chronic Obstructive Lung Disease and emphysema • Bronchial asthma • Pulmonary tuberculosis • Pulmonary abscesses • Pulmonary granulomatosis (sarcoidosis - allergic alveolitis - istiocitosis) • • • • • • • Pulmonary fibrosis Vasculitis Pulmonary oedema – ARDS Pulmonary thromboembolism Pleural effusion Broncogenic carcinoma Malignant mesothelioma. RESPIRATORY PHYSIOPATHOLOGY: • Structure and function of the lung • Breath tests: indications; • Obstructive disventilatory syndromes • Restrictive disventilatory syndromes THORACIC SURGERY • Tracheobronchial pathologies of surgical interest • Malformations and diseases of the thoracic wall • Pneumothorax - pleural empyema; • Tumors of the mediastinum; • Lung transplant: indications. Respiratory Apparatus Diseases: MALATTIE DELL’APPARATO RESPIRATORIO. G. Monsignore, V. Bellia. Ed. Mc Graw Hill, Milano 1995. MANUALE DI PNEUMOLOGIA. C. Grassi, E. Pozzi, Ed. Minerva Medica, Torino 1981 DIAGNOSIS OF DISEASES OF THE CHEST. Fraser, Parè, Parè, Fraser, Gneraux. Ed. Sauders Company. MANUALE DI ONCOLOGIA CHIRURGICA TORACICA. Ravasi, Preda. Casa Editrice Ambrosiana. BLOOD DISEASES COORDINATOR: MODULE TEACHERS MODULE TEACHERS INTERACTIVE ACTIVITIES TEACHERS MODULE TEACHERS M. Cazzola Hemalogy M. Cazzola, M. Lazzarino Hematologic Oncology P. Bernasconi F. Passamonti Pathological Anatomy U. Magrini, M. Paulli OBJECTIVES: At the end of the course the student must know: the structure and the functions of the hematopoietic bone marrow and the functional morphology of the lymphatic system; diagnostic criteria and classification of the anemias; pathogenetic mechanisms and clinical characteristics of the main anemias: hemorrhagic, hypoproliferative, carential, thalassemic, chronic disease-related, congenital and acquired haemolitic anemias, nocturnal paroxistic hemoglobinuria; pathogenetic classification of the erithrocytosis, mechanisms and diagnostic criteria; the conditions characterized by iron overload, and in particular the trasfusional iron overload and the genetic hemocromathosis; the main non-neoplastic alterations of the leukocytes; classification and molecular pathogenetic mechanisms of the leukaemias; the clinics of the myelodisplastic syndromes and the acute myeloid leukaemias; the clinics of the acute lymphatic leukaemias; classification and clinical features of mieloprolipherative diseases; classification and the molecular pathogenetic mechanisms of the malignant lymphomas; the histologic classification and clinical features of non-Hodgkin’s lymphomas and chronic linfoprolipherative diseases; hystologic classification and clinical characteristics of Hodgkin’s diseases; the classification and the clinical characteristics of the monoclonal gammopathies; the clinical classification and characteristics of the istiocytosis; the physiopathologic mechanisms of the haemostasis and the pathogenesis of the thrombosis; the classification of the thrombotic diseases, and deep venous thrombosis; the principles of piastrinic anticoagulating therapy; classification and clinical characteristics of thrombocytopenias; the classification and clinical characteristics of purpura vasculitica; the classification and the clinical characteristics of von Willebrand disease; the genetic and clinical characteristics of haemophilia, the pathogenetic mechanisms and the clinical characteristics of the main acquired coagulopathies, with particular regard to the disseminated intravascular coagulation; the fundamental elements of immunohaematology and the principles of the transfusion of blood and haemocomponents; the principles of transplant of haemopoietic stem cells and of the cellular therapy: Stem cells and haemopoietic growth factors; structure of bone marrow; hemocromocytometric examination, definition and classification of the anemias, hemorragic anemia; hypoprolipherative anemias, aplastic anemia and anemia from chronic renal insufficiency; folates, megaloblastic B12 vitamin and anemias; metabolism of the iron and anemia from iron deficiency; inflammatory cytokines and chronic inflammatory diseases anemia; thalassemic syndromes; hemolitic anemias from disorders of the erythrocitary membrane; congenital hemolitic anemias: erythrocitary enzymatic deficits and hemoglobinopathies; immunological hemolitic anemias; classification of the leukaemias; molecular cytogenetic and oncohematologic diagnosis; mechanisms of leukemogenesis; mielodisplastic syndromes; acute myeloid leukaemia; acute lymphatic leukaemia; chronic myeloid leukaemia; policytemia rubra vera; essential piastrinosis and thrombocytemia; idiopatic splenomegalies and myelofibrosis; morphology of the lymphatic system; lymphoadenopathies; molecular pathogenetic mechanisms of lymphomas; Hodgkin’s disease: histopathology and clinical aspects; non Hodgkin’s lymphoma: histopathology; indolent non Hodgkin’s lymphomas; aggressive non Hodgkin’s lymphomas; chronic lymphatic leukaemia and other chronic lymphoproliferative diseases; monoclonal gammopathies and multiple myeloma; amyloidosis; tumors of the thymus; macroglobulinemia of Waldenström, crioglobulinemia; physiopathology of the haemostasis; genetic factors and their role in the pathogenesis of the thrombosis; deep venous thrombosis and pulmonary embolism, anticoagulant therapy; thrombotic vascular thrombocytopenic purpura and other purpuras; thrombocytopenia and idiopatic thrombocytopenic purpura; von Willebrand’s disease; haemophilia; disseminated intravascular coagulation; amyloidosis; hemochromatogenesis; nocturnal parossistic haemoglobinuria; non-neoplastic disorders of the granulocytes and monocytes; leucocytes and leukopenia; blood groups; transfusion of blood and hemocomponents; transplant of hemopoietic stem cells. Recommended Texts Harrison Principi di Medicina Interna, XV Edizione, Ediz. Mc Graw -Hill 2° TERM DISEASES OF THE DIGESTIVE APPARATUS coordinator: G. R. Corazza unit: Illnesses of the digestive system Teacher: G. R. Corazza unit: Surgery of the digestive system Teacher: P. Colombo unit: Pathological anatomy Teachers: E. Solcia, E. Silini unit: Imagiology Teachers: F. Calliada unit: Pharmacology Teachers: G.M. Frigo Aims Gastroenterology: • To supply the necessary physiopathological elements to understand the main syndromes of gastroenterological area (dyspepsia, malabsorption, diarrhoea and constipation, abdominal pain and acute abdomen, hepatic and pancreatic insufficiency) • To supply the essential knowledge to the development of the main diagnostic algorithms, oriented to problems and bound to a positive cost-effectiveness relationship; • To supply the rational bases for the treatment of the main gastroenterical syndromes. Surgery of the digestive apparatus: The Integrated Course of Surgery of the Digestive Apparatus aims to introduce the essential aspects (aetiological, pathogenetic, pathological and clinical) and the fundamental bases of the gastroenteric diseases of surgical pertinence in order to allow the successive clinical and diagnostical/therapeutical approach. Anatomy and pathological histology: The course aims to teach fundamental pathological bases of diseases • To know the anatomo-pathological patterns associated to jaundice • To know the classification of pathologies of the intra- and extra-hepatic biliary ducts and their main clinical and laboratory correlations • To know the anatomo-pathological patterns, the clinical-pathological correlations and the natural history of the primitive biliary cirrhosis and the sclerosing cholangitis • To know the anatomo-pathological patterns associated with hepatic steatosis and their aetiopathogenesis • To know the natural history and the clinical and laboratorial correlations of alcoholic and non-alcoholic steato-hepatitis • To know the various types of accumulation pathologies of the liver and their criteria of classification • To know how to describe the anatomo-pathological patterns, the natural history and the clinical and laboratorial correlations of the hereditary hemocromatosis and Wilson’s disease; • To know the aetiology, the histopathological expressions, the clinical-laboratorial correlations and natural history of acute and chronic, viral and non-viral hepatitis; to know the staging criteria and histopathological grading of chronic hepatitis; • To know the aetiology, the classification and the anatomo-pathological patterns of the hepatic cirrhosis; to know the natural history and the complications of the hepatic cirrhosis; • To know the classification of the hepatic and biliary ducts tumors • To know how to describe the anatomo-pathological patterns and the diagnostic criteria of the main forms of hepatocellular tumor and of cholangiocarcinoma • To know the indications for the execution and the modalities of making an echoguided hepatic biopsy and hepatic needle-aspiration with a thin needle. Farmacology Referring to the knowledge acquired during the course of General Farmacology (pharmacokinetics, pharmacodynamics, clinical trials of drugs), the module of Pharmacology has the aim to supply the information of clinical pharmacology that are necessary for the use of drugs in gastroenteric diseases, with particular attention to drugs acting on digestive system. Topics Gastroenterology: • Objective examination of the patient of gastroenterological pertinence • Acknowledgment and interpretation of the main gastroenterological symptoms • Criteria of differential diagnosis of the main digestive syndromes. • The digestive hemorrhages. • • • • • Esophagus: Anatomo-functional principles. The disphagic syndrome. GERD. Barrett’s esophagus. Cancer of the esophagus. Esophagus diverticola. Stomach. Anatomo-functional principles. The dyspeptic syndrome. Gastritis and peptic disease. Zollinger-Ellison syndrome. Cancer of the stomach. Post-gastrectomy and resection syndromes. Intestine. Anatomo-functional principles of the small intestine and the colon. Diarrhoeas and constipation. Classification of malabsorption syndromes. The immunological answer of the intestine. The coeliac disease. Whipple’s disease. The bacterial contamination of small intestine. The minor malabsorption syndromes. Alimentary intolerances and allergies. The irritable intestine. Physiopathogenesis of chronic intestinal diseases. Crohn’s disease. Chronic ulcerative colitis. The new colitis. Diverticular disease. Cancer of the colon. Liver. Anatomo-functional principles. Jaundice. Hepatic insufficiency syndrome. The alcoholic hepatopathy. Acute and chronic viral hepatitis. Hepatic cirrhosis and complications. The thesaurismosis. Cancer of the liver. The biliary lithiasis. Pancreas. Anatomo-functional principles. The acute and chronic pancreatitis. Cancer of the pancreas. Surgery of the digestive apparatus: • Semeiology and objective examination in the diseases of the digestive apparatus. • Acute and chronic abdominal pain (physiopathological, semeiological and clinical approach). • Surgical acute abdomen: general nosographic classification(peritonitical, occlusive, vascular acute abdomen). Most frequent and significant patterns of acute abdomen. • Acute and chronic intestinal occlusion. • The abdominal hernias. Hernia incarceration. • Celiac-mesenteric acute insufficiency. • Acute appendicitis: classic form and some variants. • Tumors of the esophagus, in particular esophageal carcinoma. • Gastric precancerosis. Tumors of the stomach. Gastric carcinoma. • Inflammatory and neoplastic pathology of the mesenteric small intestine. • Intestinal polyps. • Intestinal precancerosis. • Tumors of the colon-rectum. Carcinoma of the colon-rectum. • Acute and chronic inflammatory pathology of the pancreas. • Malignant tumors of the pancreas: pancreatic carcinoma. • Endocrine tumors. • The jaundice. General treatment and aetiopathogenetic aspects. Medical and surgical jaundice. • Inflammatory pathology of the biliary ducts. Malignant tumors of the biliary ducts. • Secondary and primitive tumors of the liver. • The portal hypertension. • The hepatic cirrhosis. • Diseases of the anus of surgical interest. Pathological anatomy: E. Solcia • Gastritis from Helicobacter pylori and peptic ulcer • autoimmune gastritis and associated pathologies. Gastric lymphoma • Reflux esophagitis, Barret’s esophagus and pathology of the cardial mucosa • Risk lesions and precancerosis of the gastric and esophageal mucosa. Gastric carcinogenesis • Gastric carcinoma: histological and anatomo-clinical patterns • The precancerosis of the colon-rectum • Colorectal carcinoma • Chronic ulcerative colitis • Crohn’s disease • • • • • • Tumors of the exocrine pancreas; tumors of the endocrine pancreas. Pancreatic pathology of the diabetes Gastroenterical endocrine tumors Tumors of the thyroid. Chronic thyroiditis General treatment on the tumors of the hypophysis, parathyroid and adrenal gland. Multiple endocrine neoplasias (MEN Syndrome) Pathological anatomy: E. Silini • diseases of the intra- and extra-hepatic biliary ducts • Alcoholic and non-alcoholic steatohepatitis • Accumulation diseases (classification; hemochromatosis; Wilson’s disease) • Chronic hepatitis • Cirrhosis • tumors of the liver and of the biliary ducts. Pharmacology • Diseases of the digestive system and pharmacokinetics • Drug therapies in acid – related diseases • Drugs to increase gastrointestinal motility and peristalsis-related problems • Drugs in inflammatory bowel diseases • Antiemetic drugs Recommended Books: Harrison’s Principles of Internal Medicine, Braunwald et al. (eds), McGraw-Hill, 2001. Endocrinology and Metabolism, eds. McGraw-Hill Clinical Medicine Series, Pinchera et al. (Eds.), McGraw-Hill, 2001. Basic & Clinical Endocrinology, Greenspan et al. (Eds.), Appleton & Lange, 2000. Cecil "Trattato di Medicina Interna" Coordinamento Unigastro "Malattie dell’Apparato Digerente", UTET G.R. Corazza, V. Ziparo "Manuale di Fisiopatologia Medica e Chirurgica", Pensiero Scientifico Editore. Sabiston "Text Book of Surgery", XV edizione, 1997 Saunders Harrison’s "Principles of Internal Medicine", Mc Graw Hill Inc Dionigi "Chirurgia", seconda edizione, Masson 2000 Kumar, Cotran, Robbins "Anatomia Patologica" VI Edizione. Robbins, Kumar, Cotran "Le basi patologiche delle malattie", VI edizione Rubin, Farber "Pathology", terza edizione, Lippincott Raven. INTERNAL MEDICINE AND GENERAL SURGERY coordinator: UNIT Teachers UNIT Teacher: S.Tinozzi Internal Medicine L. Bernardi, G, Gamba General Surgery S. Tinozzi Internal Medicine Objectives Student will have to know how to describe the pathogenesis, the clinical and instrumental signs and the evolution of hypertension, and hypotension; to describe the behaviour in case of lypothymia; to describe the pathogenesis, the clinical and instrumental signs of neurovegetative pathologies; to describe the diagnostic algorithm of thoracic pain and to be able to read electrocardiography; to describe the pathogenesis of dyspnoeas and to know which pathologies can be the underlying cause; to interpret a spyrographic examination; to describe the diagnostic algorithm of asthenia and vertigo; to describe the pathogenesis and differential diagnosis of jaundice; to describe the approach to vomiting and/or diarrhoeic patient; to describe the diagnostic algorithm of lymphoadenomegalies and splenomegalies; to describe the pathogenesis, the clinical and laboratory signs and the differential diagnosis of: haemorrhagies, tremors, alcoholism and drug addictions, coma, oedematous syndromes; to describe and recognize clinical signs of acid-base and ion unbalance; to describe the approach in case of polyuria, oliguria or anuria; to describe the diagnostic algorithm of fever; to describe the pathogenesis and differential diagnosis of the pruritus. General Surgery: the student should gain a slight knowledge of general surgical pathology, knowing how to describe pathogenesis and diagnosis of affections such as: abscesses, phlegmon, fistula, forunculus, favus, hydrosadenitis, erysipelas; to recognize, to describe and to estimate an external hernia (inguinal, crural, umbilical or less frequent locations); to make differential diagnosis of hernias with tumefactions in inguino-crural region; to make differential diagnosis between herniation and other pathology of the scrotum; to identify and estimate herniae-related complications; to know the etiopathogenesis and the clinical evolution of hydrocele, pachivaginalitis, criptorchidism; to recognize from the anamnesis and palpation a tumor of the testis; to describe and diagnose from clinical and instrumental picture a gastro-esophageal reflux (with presence or absence of hyatal hernia); to characterize and differentiate organic pathologies of the esophagus from functional ones; to recognize an acute abdomen; to differentiate the several pathologies that can lead to acute abdomen;to describe the pathogenesis, the clinical and laboratory signs and to estimate the evolution of acute and chronic pancreatitis; to estimate the entity and the center of digestive hemorrhages; to describe pathogenesis, clinical signs and evolution of colon diverticulosis; to recognize and describe gallbladder calculosis and its complications; to reach by means of manual and instrumental semeiology the diagnosis of mammary neoplasia (differentiating from nonmalignant pathology); to estimate staging and grading of the mammary neoplasia in connection with therapies to carry out; to recognize and to differentiate organic and inflammatory artheriopathies; to estimate the importance of simple venous pathology (essential varicosis) from more serious pathologies (secondary varicosis, deep thrombophlebitis); to know how to differentiate arterial from venous gangrene; to know to classify, to estimate and to treat burns. TOPICS: Hernias; hydroceles; criptorchidism; tumors of the testis; diverticula and dyskinesias of the esophagus; acute abdomen; acute and chronic pancreatitis; digestive hemorrhages; diverticula of the colon; cholelithiasis; mammary pathologies; peripheral artheriopathies; phlebopathies; gangrenes; burns; arterial hypertension; the arterial shock and hypotensions; main pathologies of the vegetative nervous system; thoracic pain; dyspnoea; vertigo; asthenia; icterus; vomiting; diarrhoea; lymphadenomegalies; splenomegalies; haemorrhagic syndromes; tremors; alcoholism and drug addictions; comas; acid-base and ion unbalances; the oedematous syndromes; polyuria; oliguria and anuria; fever; pruritus. DISEASES OF THE IMMUNITARY SYSTEM AND RHEUMATOLOGY coordinator: C. Balduini unit: clinical Immunology and Allergology Professors: C. Balduini unit: Rheumatology Professors: C. Montecucco Rheumatology: • The student will learn the physiopathological bases of principal osteoarticular and connective tissue diseases, learning to distinguish and to classify the various pathological forms in relation to the clinical presentation and to the functional alterations. • The student will learn in particular the epidemiology, the clinical presentation and the prognosis of the main forms of arthritis, the systemic connective tissue disorder, the arthrosis, the main extra-articular rheumatism and of the most frequent bone diseases. • Finally the student will learn the diagnostic, clinical and instrumental approach to the main osteoarticular and connective tissue diseases with particular reference to the clinical importance of the examination of the synovial fluid. Clinical Immunology and allergology: • The student will have to know how to diagnose such diseases caused by “deficiency” or “hyperactivity” of the immunitary system; • With regards to the first case, students will review the physiological mechanisms of immune defence from pathogens, being able to identify patients having immunitary deficiency; Clinical and diagnostic aspects of immunitary deficiency will be illustrated, pointing out most common diseases of the adult age. • With regards to diseases caused by an hyperactivity of the immune system, students will be taught about physiopathology of immunitary disregulation, with detailed description of clinic and diagnostic elements of most common pathologies. • Student will be finally taught about the influence of immunitary system on pharmacologic treatments and on organ transplant. Topics: Primitive and acquired immunodeficiencies, pathogenic immunoreactions, vasculitides, IgE-related allergic diseases, drug-related reactive syndromes, immunology of tumors, immunology of transplants. DISEASES OF THE KIDNEY AND URINARY TRACT coordinator: A. Dal Canton unit: Nefrology Professors: A. Dal Canton, C. Esposito, C. Libetta unit: Urology Professors: S. Tinozzi unit: Pathological anatomy Professors: R. Rosso Aims Nephrology: The student will have to: • know how to describe and recognize in the patient the clinical signs of depletion and expansion of the extracellular volume. Know how to describe the diagnostic algorithm of the peripheral oedema. Know the means that can modify the extracellular volume • know how to describe and recognize in the patient the clinical signs of plasmatic hypohyperosmolarity. Be able to indicate how to correct an alteration of the plasmatic osmolarity. • Be able to describe the mechanisms that generate metabolic acidosis and alkalosis, knowing how to recognize the clinical signs and indicate the correction methods. • Be able to describe and recognize in the patient the clinical signs of hypo-hyperkaliemia. • Be able to interpret an urinalysis; to know how to perform an urinalysis with a reagent strip. • Know how to describe and recognize in the patient the clinical signs of nephritic and nephrosic syndrome. • Know how to describe the diagnostic algorithm of the haematuria, the proteinuria, the oliguria. • Know how to describe the pathogenesis, the clinical and laboratory signs and the evolution of the glomerulonephritides. • know how to describe the mechanisms of the acute renal failure and to indicate the diagnostic differential signs of both functional and organic sides of the problem. • Know how to describe the clinical and laboratorial signs of the chronic renal insufficiency. To know the indications and the general principles of the substitutive treatment of the renal function (dialysis, transplant). Urology: to be able to motivate the request for an urologic or uro-andrologic specialistic visit. To know how to perform a rectal exploration. To know how to do the palpation of the testis. To know how to make the transillumination of the scrotum. To know how to interpret a spermiogram. To know the catheters of common use and to know how to execute a vescical catheterism. To know how to differentiate and to interpret the localizations of urinary infections. To know how to explain and to define the risks and the consequences of the diseases with sexual transmission. To know how to orientate the patient or the couple with sexual or relational problems. To know the indication and the meaning of urethrocystoscopy and urodynamics. To know how to explain to the patient a radiological or echografic report. To recognize the urologic urgencies (acute retention of urine, priapism, torsion of the testis, renal colic, urologic traumas). To know the symptomatology and the basic diagnostic of the tumors of the testis, the penis, the prostate, the bladder and the kidney. To know how to interpret and to explain to the patient a histologic report. To know the tumoral markers and their meaning. To know how to explain to the patient the meaning of an oncological follow-up. Topics The oedema. Nephrosic syndrome. Immunodeficiencies. Notions of anatomy, histology and embryology of the urinary apparatus. Important signs and symptoms in rheumatology. The alterations of sodium balance. Alterations of the water balance and of osmolarity. Alterations of kaliemia. The rheumatoid arthritis. Pathogenic immunoreactions. Cysts and cystic diseases of the kidney. Urologic semeiotics. Instrumental and biological examinations in urology. The spondylitides-entesoarthritis. Urolithiasis. Obstructive uropathy. Renal infectious diseases. Alterations of the calcemia. Polyuria. Vasculitides. Tubular and tubulointerstial diseases. Physiopathology of the micturition. Systemic Erythematous Lupus. Antiphospholipids antibodies Syndrome. Renal pathology during systemic diseases. The urologic emergencies. Metabolic Acidosis. Metabolic Alkalosis. Systemic sclerosis. Acute renal failure. Interstitial nephritis. Glomerulonephritis. Polymyalgia Rheumatica. Immunology of the transplants. Hematuria.Tumors of the kidney. The microcrystalline arthritis. The chronic renal insufficiency. Male sterility. The Dialysis. The kidney Transplant. The extraarticular rheumatisms. Reactive syndromes to drugs. Pathologies of the prostate. Kidney and Hypertension. Tumors of the bladder and of the urinary tract. Monoclonal Gammopathies. Bone diseases. Pathologies of the testis. The sexual dysfunctions. DISEASES OF THE LOCOMOTOR APPARATUS Coordinator: Unit: Teachers Unit: Teachers Unit: Teachers F. Benazzo Orthopaedics and Traumatology F. Benazzo, R. Mora, L. Pedrotti Hand Surgery F. Benazzo Physical Medicine and Rehabilitation E. Dalla Toffola AIMS Orthopaedics and traumatology: show general issues of traumatologic care, show the clinical aspects of traumatic shock, describe the bases of fracture repair, describe the general aspects of the first aid and treatment of close and open fractures, show the general aspects of epiphyseal detachment, different bone segments fracture, luxation of different articulations; show the general aspects of capsulo-ligamentous lesions and of knee meniscus; describe general aspects of pseudoarthrosis; describe signs of main bone congenital deformities, orthopaedics aspects of neurologic infant disease, main aspects of orthopaedics disease of adolescence and childhood; describe the main aspects of inflammatory, infective and degenerative diseases of bone and articulations; describe the general aspects of muscle, tendini, peripheral nerve pathology; describe the general aspects of systemic and neoplastic disease of the bone and soft tissues; know and interpretate the most important laboratory and instrumental tests in orthopaedics and traumatologic pathology (radiologic). Hand surgery: show the main aspects of traumatic lesions of bones and soft parts of the hand, show general issues of traumatologic care for hand lesions, know and describe the main signs in the hand of congenital, inflammatory, infective, degenerative, neoplasic and evolutive diseases in muscle skeletal apparatus; know and interpretate the most important laboratory and instrumental tests in orthopaedics and traumatologic pathology of the hand. physical medicine and rehabilitation: indicate the general aspects of functional restore in traumatologic patient; describe the main technique of physical therapy and kinesitherapy for articular function restore in traumatic lesions, show the main technique of therapeutic exercise for main skeletal deformities, neurologic infant disease and orthopaedics disease of adolescence and childhood; describe the main technique of physical therapy and kinesitherapy in articular pathology, in outcomes of inflammatory and degenerative diseases; show the action of kinesitherapy and physical therapy in muscle tendini and peripheral nerve pathology; show the main tests to estimate the functional damage; know the targets of rehabilitation in most invalidant diseases. Topics: tumours of musculo-skeletal apparatus, osteoporosis; pathology of the foot, lombosciatalgy and lombocruralgy, general traumatology, arm and rachis traumatology, leg traumatology; conservative and alternative therapy in articular pathology, rachis degenerative pathology; functional anatomy of the hand, fractures and tendini pathology; canalicular syndromes, use of diagnostic instruments and therapy, techniques for functional restore in different pathology; muscle training; steps of postlesional rehabilitation. IMAGE – BASED DIAGNOSIS coordinator: F. Calliada Unit Radiologia Teachers F. Calliada, O. Bottinelli Unit Radioprotezione Teacher L. Biazzi Objectives: • The student will have to know the physical principles at the basis of image – based diagnosis. • What they are, how they work, which are the features of X-rays (physics of x-rays). • Employment of X-rays in the study of human body. X-ray application in in the study of: skeleton, cardiovascular and respiratory apparatus, urinary ways, digestive apparatus, muscle-tendinous and ligamentous apparatus. Topics: • Principles of formation of the image; • elementary semeiotics in image-based diagnosis; • traumas; inflammatory lesions; neoplastic lesions; physiological processes and their alterations; • metabolic processes and their alterations; • the imaging of geriatric patient; • from the symptom to the demand of radiodiagnosis. • Means of protection from x-ray potential damages (radioprotection). 4th YEAR’S OPTIONAL ACTIVITES (ATTIVITÀ di DIDATTICA OPZIONALE: A.D.E.) Monographic Course 10 CFU Title of the optional course Ultrasonography diagnostics of the periphereal vasculopathies Molecular Oncohematology hematological Cytomorphology Kidney and pregnancy Intervention plan of water and sodium balance Nephrotoxicity of drugs Integrated course Diseases of the Cardiovascular apparatus Blood diseases Blood diseases Kidney and urinary tract diseases, Rheumatological Semeiotics Rheumatology, Clinical immunology Elements of Sanitarian Demography Semeiotics and clinical methodology Bio-rights Human Science Referent Bernasconi P. Passamonti F. Dal Canton A. Kidney and urinary tract diseases, Dal Canton A. Kidney and urinary tract diseases, Dal Canton A. Montecucco M. Sottocornola F. Ruberto G. Odero A. Internship 30 CFU Title of the optional course Internship in Cardiology Integrated course Cardiovascular diseases Responsible Schwartz P. Internship in Cardiosurgery Cardiovascular diseases Viganò M. Internship in vascular surgery Cardiovascular diseases Odero A. Internship in Pneumology diseases of the respiratory tract Pozzi E. Internship in hematology Blood diseases M. Lazzarino, M. Cazzola Internship in Endocrinology digestive system diseases L. Chiovato Internship in Rheumatology Rheumatology, Clinical immunology M. Montecucco Internship in hemodialisis Kidney and urinary tract diseases, Dal Canton A. Internship in nephrology Kidney and urinary tract diseases, Dal Canton A. Internship in digestive system diseases digestive system diseases Corazza G. Internship in pharmacology Pharmacology Frigo G.M. OBJECTIVES AND PROGRAMMES OF THE FIFTH YEAR 5th YEAR – 1st term INTEGRATED COURSE Diseases of The Sensory system (E) Oftalmology Apprenticeship Otolaringology Apprenticeship Audiology Apprenticeship Dentistry Maxillo-facial surgery Dermatology and Plastic surgery (E) Dermatology Apprenticeship Plastic surgery Apprenticeship Infectious diseases (E) Infectious diseases Apprenticeship Pharmacology Neurologic ssciences (E) Neurology Apprenticeship Neuroradiology Neurosurgery Pathologic Anatomy Pharmacology Preventive Medicine (E) Hygiene Sociology Sanitary Economy TOTAL SSD CFU CFU Tot. C.I. CFU Profes. 10,5 MED/30 2,5 MED/31 2,5 MED/32 1 1 1 0,5 MED/28 MED/29 1 1 5 MED/35 2,5 1 MED/19 MED/08 1 0,5 5 MED/17 2,5 2 BIO/14 0,5 9,5 MED/26 4,5 MED/26 MED/27 MED/08 BIO/14 0,5 1 0,5 0,5 2,5 5 MED/42 SPS/07 SECS-P/07 3,5 0,5 1 35 5TH YEAR 2ND TERM INTEGRATED COURSES Pharmacology 2 (E) Pharmacology Internal Medicine and Medical Therapeutics CODE CFU CFU CFU Tot. C.I. Profes. 5,5 BIO/14 MED/09 5 0,5 Psychiatry (E) Psychiatry Apprenticeship Pharmacology Public Medicine (E) Forensic Medicine Apprenticeship Work Medicine Apprenticeship Communitary Medicine Pathologic Anatomy (E) Pathologic Anatomy 5 MED/25 3,5 BIO/14 0,5 1 9 MED/43 3,5 0,5 MED/44 2 MED/42 1 2 MED/08 6,5 6,5 Elective Activities 2,5 Other Activities TOTAL 1 29,5 5° YEAR – I TERM DISEASES OF THE SENSORY SYSTEM Coordinator: E. Mira Unit: Ophthalmology Teachers P. E. Bianchi Unit: Otolaryngology, Teachers E. Mira, M. Benazzo Unit: Audiology Teachers G. Precerutti Unit: Odontostomatology Teachers V. Cattaneo Unit: Maxillofacial surgery Teachers S. Galioto Teachers L. Grezzi, G. Bernasconi AIMS AND TOPICS. Ofthalmology: the student must know the anatomy and physiology of ocular apparatus. He must recognize and describe the main ocular adnexa (eyelid, conjunctiva), lachrymal apparatus and orbit diseases; recognize and describe the impairments of the fore segment of the eye specially the main disease of: cornea (inflammatory, traumatic and degenerative forms); crystalline lens (congenital and acquired cataract); fore uvea (inflammatory and neoplastic forms); identify and describe the impairment of the hinder segment, particularly main disease of: choroids, (inflammatory and neoplastic forms), retina (inflammatory, neoplastic, degenerative and vascular forms); optic nerve (disease of optic disc and of the nerve tract behind globe); recognize and describe the clinical features of congenital or acquired glaucoma with regards to physiopathology of ocular hydrodynamics and different clinical presentations; recognize and describe the refraction defects and main corrective therapy; know the physiopathology of extrinsic ocular movement and of binocular vision, describe main clinical aspects of conjoin and paralytic squint. Otolaryngology: describe pathogenic process and recognize symptoms and signs of acute and chronic inflammatory disease of the nose (infective, allergic, pseudoallergic rinhitis), of the pharynx (pharyngitis, tonsillitis), of the larynx (laryngitis of the adult and child), of the external ear (external otitis, duct eczema, forunculosis of the duct) and middle ear (acute middle otitis, secretory middle otitis, simple and colesteatomatose chronic middle otitis); identify and describe symptoms and signs of neoplasia of cervical-facial segment (oral cavity, pharynx, larynx), their locoregional metastases and notions of treatment. Know and describe the pathogenic process and diagnostic techniques of bradyacousia (trasmissive and neurosensorial) and of balance disorders (vertigo, Mènière’s disease, acute loss of vestibular function, neurinoma of acoustic nerve), know symptoms and treatment items of otolaryngologic emergency: epistaxis, dyspnoea, foreign esophageal tracheal-bronchial bodies, acute loss of uditive and vestibular function; know the general characteristics of instrumental exams of this speciality (endoscopic exams, audiometrics and impedentiometric tests, vestibular tests, nasal functionality test) and explain the answer. Audiology: know the basic principles of ear prothesis and the pertinent laws, the law obligation in industrial audiology and medico-legal issues; know the basics of preventive adult and child audiology. Odontostomatology and Maxillofacial surgery: recognize the structure of the oral cavity; know the different pathology of thick parts of the tooth and of the pulp, parodontal and periodontal, analyse and understand the origin and the complications of mucosal and bone tissue disease; know the therapeutic issues of disease by a free internship in the clinic to acquire the basics of patient approach. DERMATOLOGY AND PLASTIC SURGERY Coordinator: Unit: Teachers Interactive Exercitation Teachers Unit: Teachers Interactive Exercitation Teacher G. Borroni Dermatologia G. Borroni C. Del Forno, G. Orecchia, M. Mosca, M.A. Vignini Chirurgia Plastica e Ricostruttiva A. Faga G. Nicoletti Aims: Dermatology: students must be able to recognize the most common venereal and skin diseases and the essentials of plastic surgery, indicating the principal therapeutic addresses of the last; students must be able to individuate the situations that, in this sphere, need the specialist’s professional counseling. Topics: Dermatology: structure and development of the skin; dermatological semeiotics; viral dermatosis; bacterial dermatosis; mycosis; parasitosis; eczema; psoriasis; skin functions; bullous autoimmune diseases; non bullous autoimmune diseases; skin cancers; sexually transmitted diseases; skin and internal medicine. Plastic surgery: skin scars, skin grafts, burns and burns consequences; skin transplants and implants; non cutaneous tissues grafts. INFECTIOUS DISEASES coordinator: M. Scevola unit: infectious diseases Professors: L. Minoli, D. Scevola, A. Maccabruni, M. Mondelli unit: tropical diseases Professors: G. Filice unit: clinical parasitology Professors: M. Scaglia unit: clinical virology Professors: M. Torsellini Aims: The integrated course has as its aim the transmission of fundamental knowledge of pathogenesis, epidemiology, clinical presentation, diagnosis and therapy of the diseases caused by infectious agents with particular reference to contagious diseases. The course provides frontal lessons and interactive lessons using instruments (PC, microscope, laboratories), to allow the student by the end of the course to establish a diagnostical, clinical and laboratoristic path of the most common infectious forms and to set up an antibiotic therapy, a general medical treatment and also to put into action the preventive treatments and the requested measures of Public Health. Methodologies of laboratory to isolate and identificate of pathogenic agents, bacteria, virus, protozoi, helminths, fungus, will be illustrated as well. Topics: New pathogens of the last decade; AIDS; viral hepatitis; exanthematic diseases and infectious diseases of the pediatric age; diagnosis of viral infections; infections of Central Nervous System; tetanus and botulism; approach to the febrile syndromes; infectious endocarditis; the septicaemias; infectious gastroenteritis; infectious diseases of the nervous system (meningitides, BSE etc.); viral infections in pregnancy (ToRCH complex); antivirals drugs and resistances; resistance diagnosis; infection-disease from HIV; nosocomial infections; features of Tropical Medicine. Recommended Books Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Moroni, Esposito e De Lalla, Malattie Infettive, Masson Editore Filice, Malattie Infettive, Mc Graw Hill editore, NEUROLOGICAL SCIENCES coordinator: UNIT Teachers Interactive exercitations teachers UNIT Teachers UNIT Teachers UNIT Teachers UNIT Teachers V. Cosi Neurology V. Cosi, A. Moglia, L. Montalbetti, G. Sandrini M. Ceroni, M. Versino, P. Bo, A. Costa Neurosurgery C. Arienta, S. Pezzotta Neuroradiology V. Cosi Neurophysiopathology A. Moglia Neurologic Rehabilitation G. Sandrini AIMS Students must promptly recognize that the patient is affected from a disorder of the central or peripheral nervous system, and must be able to determine the emergency level that requires the patient to be addressed to a neurologist or to a neurosurgeon or, in less severe cases, students must be able to formulate a diagnostic and lab protocol. Students must have knowledge about the physiopathological processes that may involve the control systems of the voluntary, involuntary and reflex motor activity and those of the muscular tone. Students must know the physiopathological processes of sensitivity disorders and the related clinical syndromes and must be able to recognize and describe consciousness disorders (mental confusion), language disorders (motory and sensory aphasia), intentional gesture disorders (apraxia), recognition disorders (agnosia) and memory disorders. Students must be able to distinguish central and peripheral paralysis and must be able to diagnose the anatomical site of the lesion. Students must be able to recognize and describe symptoms and signs due to peripheral nervous system involvement (paresis, osteotendinous reflexes disorders, subjective and objective sense disorders, fasciculations and myokimias, trophism modifications, vegetative disorders). Students must know the principal neurological syndromes: pyramidal, extrapyramidal and cerebellar. They must know the clinical features of the most important pathologies, by the epidemiological point of view, as epilepsy, cerebrovasculopathies, dementias, demyelinating diseases, headaches, traumas and tumors of the nervous system, substance abuse pathologies, in particular alcohol abuse pathologies and the clinical features of less frequent pathologies, but still meaningful and important (motoneuron diseases, myopathies, myasthenia). Students must recognize the different types of epileptic seizure and must know the causes of epileptic crisis and epilepsy. They must be able to perform the differential diagnosis between epileptic seizure and paroxysmal non epileptic episodes (syncopes in particular). They must know the main sleep disorders, the different types of tremors, and the other pathological involuntary movements. They must know the problems related to emergencies in neurology (stroke, head injury, intoxications, metabolic comas). They must know and understand the main features of electromyographic and electroneurographic diagnostics. Students must know when to perform a special or normal electroencephalographic exam, and other normal neurophysiological exams as evoked motory potentials, evoked sensory potentials, repetitive electrical stimulation strategies, and they must know when to perform the color doppler ultrasonography of the supraaortic trunks and the transcranic doppler. They must know when to perform rachicentesis and cerebrospinal fluid examination. Students must know the different neuroradiologic study methods as the computed tomography, the magnetic resonance imaging, and the digital angiography. They must be able to determine which is the most appropriate technique for the different clinical situations. They must be able to relate the radiographic image to the anatomical site. They must know the main evaluation scales applied for the most important pathologies and how to cure the principal neurological diseases. TOPICS Motor control: organization of the motor system- Semeiotics of motricity- Central and peripheral paralysis; Sensitivity: anatomo-physiology of sensitivity- sensitivity disorders; Main syndromes: pyramidal syndrome- extrapyramidal syndromes- cerebellar syndrome; Cortical syndromes; Superior functions: vigilance and disorders (mental confusion)- language and aphasias- apraxiasagnosias- memory disorders; Comas: physiopathology- general and neurological examination of the patient in coma- evaluation scales and instrumental exams- causes- prognosis- cerebral death; Semeiology of cranial nerves: optic nerve- oculomotion disorders- trigeminal nerve- facial nerve – other cranial nerves; Clinical electroencephalography: definition- origin of EEG potentials: normal and pathological activities- principal EEG pictures related to the main neurological diseasesindications and limits of EEG- activation trials- prolonged monitoring; Epilepsies: definition of epilepsy and epileptic seizure- incidence and prevalence- classification of epileptic seizuresclassification of epilepsies: the most important syndromes; causes of epilepsy- diagnosticsdifferential diagnosis- prognosis- therapy- psychosocial and medicolegal problems; Sleep: physiological sleep- study methods- international classification of sleep disorders- insomniashypersomnias; Headaches and face aches: the headache patient- classification and differential diagnosis of headaches- headache syndromes and their treatment: migraine with and without aura- tensive headache- cluster headache- trigeminal neuralgia- particular forms of headache: post injury headache- strain headaches and dangerous headaches- diagnostics and therapy; Cerebrovascular diseases: epidemiology- risk factors- pathogenesis: atherothrombotic brain infarction- cerebral embolism- lacunar infarction- intracerebral haemorrhage- clinical features: symptoms and course of the cerebrovascular diseases with reference to the lesion site – differential diagnosis- therapy; Cerebrovascular pathology concerning neurosurgery: anatomy and physiology of the cerebral circle- cerebrovascular haemorrhagic disease- subarachnoid haemorrhage- neuroradiologic diagnostics in the acute and chronic cerebrovascular pathology (ischemic lesions, haemorrhages, lacunas, hypertensive encephalopathy, leukoaraiosis and their differential diagnosis); Primitive and secondary brain tumors- hydrocephalus: gliomasmeningiomas- acoustic nerve neurinoma- hypophysis adenomas- tumors of the sellar regionmetastatic brain tumors- therapies- Infant brain tumors: medulloblastomas, supratentorial tumorsHydrocephalus: introduction-cerebrospinal fluid circulation- etiology- clinics- diagnosticstreatment- normotensive communicating hydrocephalus- clinics- diagnostics- treatment- Diagnostic imaging with CT, MRI and angiography of intra and extra axial brain tumors with an outline of the physiopathology of the CSF system and of the hydrocephalus; Spinal tumors: clinics- diagnosticsextramedullary intradural tumors- intramedullary tumors- treatment; Cranial-cerebral injuries: cranial fractures- post injury CSF losses- post injury pneumoencephalus- extradural haematomaacute and sub acute subdural haematoma- chronic subdural haematoma- post injury subdural hygroma- post injury contusions and lacerations- post injury vascular lesions- post injury neurological consequences; Vertebro-medullary injuries: stability/instability concept- vertebral fractures- medullary lesions- treatment- consequences; Disc lesions and vertebral stenosis: etiopathogenesis- anatomy and physiology- physiopathology- clinics- cervical disc lesions- thoracic disc lesions- lumbar and sacral disc lesions- diagnosis- prognosis- surgical therapy; Spinal dysraphism: syringomyelia; Dementias: the demential syndrome- classification of dementiasPrimary or primary degenerative dementias: histopathologic alterations, biochemical alterations, etiopathogenesis, clinics- Multiinfarctual dementias: etiopathogenesis, clinics- PseudodementiasSubcortical dementias- Transmittable dementias (Jacob-Creutzfeldt)- therapy; Multiple sclerosis: classification of the inflammatory demyelinating pathologies of the CNS- epidemiology- etiology and pathogenesis: genetic susceptibility, immunology, viruses- pathological anatomyphysiopathology of symptoms and signs- symptoms and clinical features – evolutive forms, natural history and prognosis- CSF examination- neuroradiologic diagnostics and differential diagnosis with MRI- clinical neurophysiology- criteria for the clinical diagnosis- diagnostic clinical instrumental protocol- differential diagnosis- Therapy of the acute phase- symptomatic therapies- treatment to avoid relapses and progression; Extrapyramidal diseases: idiopathic Parkinson: neurotransmitter alterations; etiopathogenesis; clinical signs (motory, neurovegetative, psychic); course; treatments; long term levo-dopa syndrome- Degenerative parkinsonisms ( supranuclear progressive paralysis)- Secondary parkinsonisms (neuroleptics)- Huntington’s chorea- Wilson’s disease- Semeiotics of pathological involuntary movements; Pathology of peripheral nerves: anatomopathological processes: wallerian degeneration, segmentary demyelination, axonal degeneration- Features of electrophysiologic diagnostics: electromyography, conduction speeds studies- Symptoms of peripheral neuropathies- syndromes classification of peripheral neuropathies- compressive syndromes- toxic and metabolic neuropathies (alcoholic and diabetic)disimmune neuropathies (polyneuritis of Guillan-Barré-Strohl); Amyotrophic lateral sclerosis: neuropathology and etiopathogenesis- clinics- course, diagnosis and treatment; Myopathies: classification- pathological anatomy- semeiotics- muscular dystrophies- inflammatory myopathiesmyotonic dystrophy- other myopathies; Myasthenia gravis: clinics, course; thymus alterations and other related pathologies; etiopathogenesis; diagnosis; treatment- Lambert-Eaton’s myasthenialike syndrome; Neuro AIDS: neurological syndromes in the serum conversion period- chronic neurological syndromes- AIDS dementia complex; Alcohol related neurological problems: Delirium tremens- Wernicke’s encephalopathy- Korsakoff’s syndrome. RECOMMENDED BOOKS J. Cambier, M. Masson, H. Dehen: Neurologia, IX ed., Masson 2001 TO BE INTEGRATED WITH: R. Dionigi: Chirurgia, III ed., Masson 2002 [Interesting sections: signs and symptoms in neurosurgery – cranio-cerebral and vertebro-medullar traumas– brain and spinal tumors – paediatric encephalic tumors – hydrocephalus cerebrovascular pathologies in neurosurgery – vertebral lesions and sthenosis] G. Scotti: Neuroradiologia, Masson 1996 C. Loeb, E. Favale: Neurologia di Fazio Loeb, 2 volumi, Soc. Ed. Universo 2003 R.D. Adams, M. Victor: Principi di Neurologia, VII ed., Mc Graw-Hill 2001 PREVENTIVE MEDICINE COORDINATOR C. Meloni UNIT General and Special Hygiene TEACHERS C. Meloni UNIT Food and Nutrition Hygiene TEACHER C. Roggi Interactive C. Gallotti, M. Laddomada, L. Maccarini, M. Rossi exercitation teachers Student must be able to: • Understand the principles and the methodology of Preventive Medicine • Know the origin, the modalities of action and the expectable effects of the main health risk factors, of genetic, environmental and behavioral origin. • Acquire the knowledge, the motivations and the instruments to use the means of health promotion and prevention of the diseases. • Understand the methodology and the means of intervention of Health Education (promoted by Healthcare system) • Know the principles and the techniques of programming, organization and performance of the activities of primary and secondary prevention of infectious and noninfectious pathologies in the high-risk population. • Acquire the basic notions and the effective applications of nutrition highly summarized indication of the contents of the lessons: • Introduction to the course: purpose and limits of the prevention, its stages or phases • The primary prevention and its levels of participation: The prevention in nutrition • Prevention in nutrition: The Sanitary Education: contents and means of application. • Educational techniques • Epidemiology and general prevention of the infections • Active and passive immunitary protection. • Second level of preventive medicine: environmental damage factors and their effects. • Environmental factors of risk and damage and modality of correction of the related risk • Behavioural risk and damage factors • Third level of preventive medicine: appraisal and correction of the disease risk • The premature diagnostic assessment and its usefullness in prevention of neoplastic pathologies. • Notions of sanitary economy and management applied to prevention. • Program and organization of healthcare services related to prevention. RECOMMENDED BOOKS L. Checcacci, C. Meloni, G. Pelissero, Hygiene, 2° ed. Casa Editrice Ambrosiana, Milano M.J. Rosenau, public health and preventive medicine, ed. AppletonCenturyCrofts S. Barbuti, E. Belleli, G.M. Fara, G. Giammanco, Hygiene e Medicina Preventiva, ed. Monduzzi Editore 5TH YEAR - II TERM PHARMACOLOGY II (special pharmacology) Coordinator: G. Frigo Unit Special Pharmacology Teachers GM. Frigo, F. Crema Unit Neuro-psycho-pharmacology Teachers E. Perucca, G. Gatti Unit Chemotherapy Teachers A. M. Ferrara, A. M. Fietta Unit Toxicology Teachers L. Manzo, M. De Bernardi di Valserra Objectives The course will provide the student a complete survey of main drug groups, with the description of their effect mechanisms, adverse reactions, indications and application methods. Dosage of individual drugs and their classification within contemporary medical practice. Basic survey of the pharmacotherapy of the most important serious clinical conditions and intoxications. Risk-benefit of the drugs. Students will be able to: - prescribe all the types of drugs they may come across in clinical practice in a formal and correct manner, - master basic principles of pharmacodynamics and pharmacokinetics, - have basic knowledge of main drug groups, - master basic principles of effective pharmacotherapy using these drugs, - know the main adverse reactions to drugs and the ways of their prevention and treatment, - orient themselves in the sources of information necessary for a doctor in clinical practice. - Delineate desired therapeutic outcomes. - Critique the pharmacotherapeutic regimen and modify the regimen, as necessary. - Identify ongoing or potential drug-related problems. - Delineate realistic and cost-effective monitoring plans and use those plans to evaluate and change therapy. The course provides theory (frontal lessons) and interactive activities, about the application to therapy of general pharmacology principles through the systematic approach of drug classification. Various drug categories will be classified in therapeutic groups, referring to the mechanism of action and the structure-action relationships, with particular attention to therapeutic indications, to clinical pharmacology, to administration modalities and pharmacokinetics, to drug-drug interactions, to contraindications and side effects and also to applied criteria for polypharmacologic approach. The applications of principles of general toxicology to most important aspects of clinical toxicology. Subjects will be carried out in units. Topics: Cardiovascular pharmacology: antianginous; antihypertensive and therapy of the hypertension; cardiac glycosides and other positive inotropic drugs; antiarrhythmics; antidislipidemic; anticoagulants; thrombolitics; antiaggregants; diuretics. Haemopathies pharmacology; endocrine and metabolic pharmacology: hypophisary hormones; thyroidal hormones and anti-thyroidal drugs; corticosurrenal hormones; Diabetes pharmacotherapy: oral insulin and hypoglicaemic agents; estroprogestinic and androgens drugs; pharmacology of the contraception; pharmacology of the steady state of calcium; vitamins; pharmacology of the neurovegetative system and the visceral functions: gastrointestinal pharmacology: antiulcerants, prokinetics, lassatives, antidiarrhoeics, antispastics; antiasthmatic and broncholytic agents; antihystaminics; anti-hemicranial; uterine motility drugs; immunopharmacology and pharmacotherapy of inflammatory states: immunomodulators and immunosuppressors; non-steroidal antinflammatory drugs; antinflammatory corticosteroids; rheumatoid arthritis drugs; anti-gout; antipyretics. Neuropsychopharmacology: antipsychotics; antidepressants; ansiolitics; hypnotics; greater analgesics and pain pharmacotherapy; antiepileptics; antiparkinson drugs; myorelaxant drugs. General and local anaesthetics. Chemotherapy: beta-lattamate antibiotics; aminoglycosides; chinolones; macrolydes; lyncosamides; glycopeptides; tetracyclins; cloramphenycol; sulfamydes; riphampicin; antimychobacterial drugs and antituberculous therapy; antimycotic; antivirals; antiprotozoics; antihelmintics; antiblastics; Toxicology: apparatus and organ toxicity (liver, kidney, nervous system, respiratory apparatus, riproductive apparatus); alcoholism and alcohol-related pathologies; acute poisonings (toxic gases, mushrooms, chemical products, domestic products, psychodrugs; principles of diagnosis and therapy); toxicological risks in pregnancy; poisonings in particular situations (pediatric and geriatrical age); drug abuse and drug addictions; toxic effects of the environmental pollution. Recommended books: Goodman & Gilman’s : Le Basi Farmacologiche della Terapia, 8a edizione, Zanichelli. B.G.Katzung: Farmacologia General e Clinica, Ed. Piccin Fulgraff G: Farmacologia General e Clinica, Edizioni Mediche Scientifiche Internazionali. PSYCHIATRY coordinator: UNIT Teachers Interactive exercitations teachers UNIT Teachers UNIT Teachers F. Petrella Psychiatry F. Barale, F. Petrella S. Ucelli di Nemi, P. Ambrosi, P. Ferrari, V. Berlincioni Mental Hygiene E. Caverzasi Medical Psychology F. Barale AIMS Students must know the essentials about the origin and the development of psychiatry and must be able to relate this knowledge to the right historical period. Students must know the theoretical fundamentals of psychiatry and the principal disease models in psychiatry: the medical model, the alternative models. Students must know the fundamental principles of social psychiatry: the role of personal interactions in the psychiatric theories; the essentials about the stress concept and the vital event concept. Students must know the principal elements of psychiatric epidemiology and research methodology in psychiatry. They must know the essentials about psychiatric genetics and cerebral biochemistry. They must know the essentials about psychiatric semeiotics: physical and psychic examination, and anamnesis. They must know the methodological fundamentals of psychopathology and the essentials about psychic functions and their alterations: consciousness, attention and vigilance; Memory; Perception; Thinking; Affectivity; Instincts; Will and activity; Intelligence. They must know the principal instruments and diagnostic methods: talk, interview, testing, neurophysiopathologic and psychoneuroendocrine examinations. They must know the main principles that regulate the classification of psychic disorders and the essentials about the psycho organic syndromes: Dementias; Delirium; Substance abuse related disorders. They must be able to figure the schizophrenia problem in an historical, nosographic, and clinical perspective. They must know the essentials about the schizophrenic disorders: clinics; diagnosis and differential diagnosis- Etiopathogenesis; Epidemiology; Genetics; Functional and biochemical alterations; Psychodynamic and relational problems; Therapy: pharmacotherapy; other biological therapies; psychotherapy; institutional therapy. Students must know the essentials about delirious disorders: nosography; clinics; particular clinical forms; course and therapy. They must figure the mood disorders problems in their psychopathological, nosographic and clinical aspects and they must know the essentials about their etiopathogenesis: biology; genetics; psychodynamic aspects. Students must know the main clinical aspects of mood disorders: mania; depression; bipolar disorders; unipolar disorders; dysthymia; cyclothymia; suicide and suicide attempt. They must figure the neurosis problem in an historical, nosographic and anthropological perspective. Students must know the principal clinical forms of neurosis: anxiety disorders; phobia; obsessive-compulsive disorder; hysteria; somatoform disorders. They must focus their attention on the personality disorders problem. Students must know the basics of psychiatric therapy: the therapeutic relation; the pharmacological therapy: anxiolytic drugs; antipsychotic drugs; antidepressant drugs; mood regulators; psychiatric assistance; psychiatric legislation. Students must figure the psychotherapy problem in an historical perspective and must know the basics of the principal psychotherapy types. Students must know the essentials about the psychotherapeutic practice: the psychotherapeutic function of the doctor; the doctor as a medicine; the doctor and the patient that somatizes; models, conceptions and techniques in the psychotherapeutic practice; indications for psychotherapy; psychotherapeutic aspects in the treatment of the most important psychiatric disorders. TOPICS PSYCHIATRY: history of psychiatry; the crisis of psychiatry; general psychopathology; psychiatric nosography; psychiatric assistance; the psychoanalysis contribute; the psychotic structure; schizophrenia; maniac depressive psychosis; morbid appetites: alcohol and substance abuse; psychiatric therapies. CLINICAL PSYCHOLOGY AND PSYCHOTHERAPY: the delirious experience: psychopathological, psychological, clinical and therapeutic features; the schizophrenic experience: psychopathological, psychological, clinical and therapeutic features; mood and mood disorders: psychopathological, psychological, clinical and therapeutic features; anxiety and anxiety disorders: psychopathological, psychological, clinical and therapeutic features; the human personality and its disorders; eating habits and eating disorders; consciousness and memory disorders, delirium; human sexuality and its disorders; the body in psychiatry and the somatoform disorders. RECOMMENDEND BOOKS Giberti F., Rossi R., Manuale di Psichiatria. Piccin OTHER INFORMATION: De Martis D., Petrella F., Ambrosi P., Fare e pensare in psichiatria, Relazione e istituzione, Raffaello Cortina Petrella F., Turbamenti affettivi e alterazioni dell'esperienza (Sezioni I, II, IV, VI), Raffaello Cortina Kapln: Psichiatria, Ed. Centro Scientifico Internazionale. PUBLIC MEDICINE: PREVENTIVE MEDICINE + SEE 6th YEAR: WORK MEDICINE + FORENSIC MEDICINE PATHOLOGICAL ANATHOMY Coordinator: U. Magrini Teachers: U. Magrini, E. Solcia, E. Silini, M. Paulli, R. Scelsi, R. Rosso AIMS: Lymphohaematologic pathology: - Students have to know lymphatic system (thyme, lymph nodes, MALT) and bone marrow structure and functions; - Most important non–neoplastic pathologies, which of them can be confused with malignant lymphomas and how the physician can diagnose it correctly; - Most important histological characters, natural history, prognostical factors and complications of Hodgkin’s lymphoma and of most common non-Hodgkin’s lymphomas; - Students must be able to explain the meaning of “staging” and “grading” during different types of lymphomas, and they have to know how to do a correct staging; - Diagnostic and prognostic principles of lympho-plasmacellular tumours, especially of myeloma, and of the main thyme tumours; -Main causes of mediastinic obstruction syndrome and how to diagnose it; - Classification and natural history of myeloprolipherative syndromes; - Natural history, diagnosis and classification of Langerhans’s cells Histiocytosis; - Possibility of finding primitivity during a metastatic lymph node pathology; - Indications to propose a needle biopsy, a lymph node and a bone marrow biopsy, how to do it, how to interpret the results; - How to communicate to patients or to their relatives this result, in a psychologically and scientifically correct way. Feminine genital apparatus and breast pathology: - Structure of feminine genital apparatus and of the breast and their changes during menstrual cycle, pregnancy and hormonal want of balance conditions; - Students have to be able to define what endometriosis is, to know its principal localizations and complications; - Epidemiology and natural history of pre-neoplastic vulva, vagina, uterus cervix and endometrium lesions, how to diagnose them, how they shape; - Epidemiology, risk factors, natural history and pathological anatomy prognosis elements of uterus tumours; - Possibilities and limits of pap-test in diagnosis and screening; - Localizations, evolution, complications of leiomuscular feminine genital apparatus tumours; - Macroscopic aspects and different histological types of ovary tumours, their natural history, how to diagnose them; - Most important endometrium, ovary and tubes pathologies which can lead to sterility; - Students have to be able to define ectopic pregnancy, its localizations and complications - Most important types of trophoblastic pathology, treatment possibilities; - Students have to be able to understand and explain to patient the results of a pap-test, or of a cervix or endometrium biopsy; - Epidemiology, risk factors, natural history and prognosis of different types of breast cancer; - Most important microscopic and macroscopic aspects of benign breast tumours; - How to diagnose mammary nodules (needle biopsy, extemporaneous biopsy, surgery and their limits). Locomotor apparatus and soft tissues: - Tumours that most frequently generate bone metastasis, where this metastasis localize and which changes they produce in that site; - Most important histological types of bone and cartilage benign (exostosis, chondroma, osteoid osteoma) and malignant (osteosarcoma, chondrosarcoma, Ewing’s tumour) tumours, their localization and natural history; - Differential diagnosis between osteolithic lesions (single and multiple); - Possibilities and limits of histological diagnosis of bone lesions; - How to classify the most common benign (lipoma, fibromatosis, haemangioma) and malignant (liposarcoma, angiosarcoma, malignant fibrosis histiocytoma) tumours of soft tissues. Nervous central system : - Vascular alterations responsible for brain lesions, and evolution of ischaemic and haemorrhagic lesions; - Most important types of brain haemorrhage and stroke, and relationship between site of lesions, symptoms and prognosis; - Causes and most common types of meningeal inflammation, their evolution and complications; - Most important types of brain tumours, related to age and site of lesion; student have to know their natural history and possibilities of histological diagnosis. Tegumentary apparatus: - Epidemiology, sites and most common shape of cutaneous pigmentated tumours, different types of melanoma, their natural history and relations between histology and prognosis. Paediatric pathology: - General characters of childhood malignant tumours and relation between different tumours and age; Neuroblastoma, its localizations, stadiation and natural history. Pathology of face and neck: - Most important tumours of face and neck (benign and malignant laryngeal, rhinofaringeal, mouth, ear and orbital tumours); - Relations between natural history, site and stadium of different pathologies; - How to diagnose these lesions, how to make a prognosis (histological and cytological characters); - Differential diagnosis between cervical tumefactions, possibilities of pre-surgical treatment diagnosis (needle biopsy). Topics: Lymph nodes disease; NHL classification; NHL B low and high grade; NHL T; HL; thyme tumours; lymph node metastasis; mieloprolipherative disease; Langerhans’ cells Histiocytosis; benign breast tumours; differential diagnosis; in situ breast cancer; infiltrated breast cancer; esophagitis; gastroduodenal peptic ulceration; gastrointestinal endocrine tumours; ischemic bowel disease; inflammatory bowel disease; tumours and pre-cancerous lesions of esophagus, stomach and bowel; inflammatory and neoplastic pathology of pancreas; endocrine system disease; diffuse endocrine system and its pathology; gonads endocrine functions; arteriosclerosis; aneurysms; hypertension; varicose veins; endocardium pathology; congenital cardiopathy; ischemical cardiopathy; pericardium pathology; hydrocephalus; brain tumours; brain stroke and haemorrhage; multiple sclerosis; childhood malignant tumours; feminine genital apparatus tumours; endometrial hyperplasia; endometriosis; acute lung failure; pneumonia; lung tumours; pleural tumours; mediastinum pathology; chronic bronchitis; emphysema; lung interstitial disease; lung embolism; lung haemorrhage and ischaemia; tuberculosis; chronic hepatitis; kidney pathology; kidney stones; kidney infections; kidney vascular disease; kidney tumours; prostate and testicle pathology; benign and malignant tumours of soft tissues (vessels, muscles, nerves, connective tissue, skin, Ewing’s sarcoma). Recommended Books Robbins S.L., Le basi patologiche delle malattie, Piccin 2000 5th YEAR’S OPTIONAL ACTIVITES (ATTIVITÀ di DIDATTICA OPZIONALE: A.D.E.) Monographies and SEMINARS : to be defined Internship: Optional Course Title Integrated Course Responsible Dermatology Internship Dermatology and plastic surgery G. Borroni Pathologic Anatomy Internship Pathologic Anatomy Magrini U. Plastic surgery Internship Dermatology and plastic surgery Faga A. Neurosurgery Internship Neurologic Sciences Arienta C. Neurology Internship Neurologic Sciences V. Cosi Psychiatry Internship Psychiatry Petrella F., Barale F. Ophtalmology Internship Diseases of Sense Organs Bianchi P.E. OBJECTIVES AND PROGRAMMES OF THE 6TH YEAR 1ST TERM INTEGRATED COURSE CREDITS SUBJECTS INTERNAL MEDICINE 15 GENERAL SURGERY 14 GENERAL AND SPECISALISTIC PAEDIATRICS (E) 21 WORK MEDICINE (E) GYNAECOLOGY AND OBSTETRICS (E) 11 16 Internal Medicine Medical Therapeutics and Thermal Medicine Medical Genetics General surgery Oncological Surgery Paediatrics Preventive and Social Paediatrics Paediatric Surgery Paediatric Neuropsychiatry Work Medicine Industrial Hygiene Preventive Medicine and Psychotechnique of the Work Industrial Toxicology Gynaecology and Obstetrics Human Reproduction Physiopathology Gynaecologic Oncology Prenatal Age Medicine 2nd TERM INTEGRATED COURSE INTERNAL MEDICINE (E) CREDITS SUBJECTS 15 MEDICAL-SURGICAL EMERGENCIES (E) 26 GENERAL SURGERY (E) 13 FORENSIC MEDICINE (E) 10 Internal Medicine Emergency Medicine Emergency Surgery Intensive Therapy Surgery Forensic Medicine Deontology and Medical Ethics Forensic Toxicology Forensic Psychopathology Social Medicine INTERNAL MEDICINE R. Fogari Coordinator Unit Medicina Interna Teachers E. Ascari, C. Balduini, R. Fogari Interactive exercitation teachers Unit Teachers Unit Teachers G. Gamba, P. Noris, A. Mugellini Medical therapeutics and Thermal Medicine G. Ricevuti, L. Ariati Medical Genetics C. Danesino Aims: students must be able to integrate symptoms, signs and structural and functional alterations to globally evaluate the health situation of a single adult patient with reference to the preventive, diagnostic, prognostic and therapeutic aspects. Students must be able to analyze and solve clinical problems concerning internal medicine by the diagnostic and therapeutic point of view, evaluating the risks and the risk-benefit ratio of the therapeutic interventions. Medical genetics: students must learn the rational behavior, in strict correlation with their practical application, necessary to identify the possible genome alterations responsible for the clinical picture. Students will learn how to integrate the medical genetics methods with those specific of other clinical branches, to arrive to the right disease management and to the disease prevention in other relatives. Topics: Internal medicine: presentation and discussion about clinical cases concerning hematological, oncological and gastroenterological pathologies; presentation and discussion about clinical cases concerning cardiovascular and pulmonary pathologies. Treatment of malignant neoplasms, cardiovascular diseases, haemopathies, nephropathies, connective tissue diseases, endocrinopathies, and metabolism diseases. Presentation and discussion about clinical cases concerning immune system pathologies. Presentation and discussion about clinical cases concerning hepatic and renal pathologies. Presentation and discussion about clinical cases concerning metabolism and endocrine system pathologies. Treatment of infectious diseases, gastroenterological, hepatic, biliary, pancreatic, pulmonary diseases. Medical genetics: cultural setting, knowledge and methodology of investigation, bibliographic up dating, necessary for genetic counseling, for identifying the disease and the subjects that may develop genetic pathologies. GENERAL SURGERY Coordinator Unit Teacher Unit Teacher Interactive exercitation teacher E. Forni General Surgery A. Zonta Oncological Surgery P. Dionigi G. Fraipont Targets: The student must be able to: recognize symptoms, signs, structural and functional impairment of the main benign and malignant disease of surgical interest in connection with the health status of the adult or elderly patient. He must be able to appraise prognosis, create the correct diagnostic path, suggest the therapeutic and rehabilitative items considering the costbenefit ratio. Topics: neoplastic growth and metastatization process. Primitive and secondary tumors of the liver; malignant pancreas tumours; benign and malignant pathology of the skin, breast, spleen, peritoneum and retroperitoneum, portal and mesenteric circle, kidney and urologic-gynecologic apparatus. General notions of organs trasplantation and details of kidney, liver, pancreas, bowel, multivisceral trasplantation. Benign and malignant pathology of endocrine glands, especially thyroid, parathyroid gland, endocrine pancreas, suprarenal glands, carcinoid. Diaphragmatic hernia and hernia of the abdominal wall. RECOMMENDED Dionigi R., Chirurgia, Ed. Masson. BOOKS: Colombo C, Paletto AE, Trattato di Chirurgia, Ed Minerva Medica Davis-Christopher, Sabiston, Textbook of Surgery, Ed. Saunders GENERAL AND SPECIALISTIC PAEDIATRICS Coordinator G. Rondini Unit Pediatria Teachers G. Rondini, M. Bozzola, A. Marchi, G.L. Marseglia Interactive exercitation teachers: D. Larizza, M. Cisternino Unit Chirurgia Pediatrica Teacher G. B. Parigi Unit Neuropsichiatria Infantile Teachers G. Lanzi, E. Fazzi Interactive exercitation teacher F. Piazza AIMS General Paediatrics: Through anamnesis collection and physical examination, students must be able to define diagnosis and therapeutical approach of the most common pathologies of the evolution age, using wellknown notions of physiopathology. Paediatric Surgery: Students must know most useful notions to focus on indications for surgical treatment in paediatrics. Paediatric Neuropsychiatry: Students must be able to use essential means to suspect a neuropsychiatric pathology in order to request a specialistic consultation. TOPICS The program consists of the evolution age phisiopathologic peculiarities and the presentation/discussion of clinical cases regarding the most frequent paediatric pathologies. The program is made up of the following specific features: 1) Neonatal pathology-Neonatology and Intensive care - Very important topics: basic features of intrauterine life pathology and phisiopathology; assistance to the normal and pathologic newborn;neonatal screening;very small for gestational age newborn; newborn of diabetic mother; hypoxic-ischaemic-haemorrhagic encephalopathy; hyaline membranes disease; bronchopulmonary dysplasia; neonatal jaundice; gastrointestinal pathology in the newborn; oesophageal fistula; hypertrophic stenosis of the pylorus; necrotizing enterocolitis; neonatal infections and sepsis; neonatal convulsions; hypoglycaemia of the newborn. Optional topics: adaptation to extrauterine life; small for gestational age newborn; cardiovascular collapse in the newborn; nutrition of the healthy and pathologic newborn;congenital hip dislocation; renal pathology. 2) Endocrinology - Very important topics: basic features of auxology; height deficits; precocious and delayed puberty; hypothyroidism; hyperthyroidism;congenital adrenogenital syndrome; insulin dependent diabetes mellitus. 3) Haematology and Oncohaematology - Very important topics: anemias; lymphomas; acute and chronic leukemias;neuroblastoma. Optional topics: adenomegalies; spleno-hepatomegalies. 4) Gastroenterology - Very important topics: gastroesophageal refluxes and vomiting;malabsorptions;chronic inflammatory bowel disease; gastroenteritis. 5) Chromosomal pathology - Very important topics: Klinefelter’s syndrome,Turner’s syndrome, Down’s syndrome 6) Immunology and allergology - Very important topics: congenital and acquired immune deficiencies;bronchial asthma. 7) Rheumatology - Very important topics: rheumatic disease; collagen pathologies. Optional topics: vasculitis 8) Nephrology and urology - Very important topics: glomerulonephritis; glomerulonephrosis; urinary tract infections. 9) Infectious diseases - Very important topics: fever; infectious exanthems; meningitis and encephalitis; tuberculosis; infectious mononucleosis. 10) Vaccines - Very important topics: compulsory and optional vaccines. 11) Bronchopneumology - Very important topics: laryngitis, otitis; bronchopneumonia; bronchiolitis. Optional topics: chronic pulmonary diseases; pleuritis. 12) Cardiology - Very important topics: congenital and acquired cardiopathies; cardiovascular collapse. Paediatric surgery - Very important topics: neonatal surgical pathology; general surgical pathology: hernia, cryptorchidism, hypospadias, phimosis, intestinal intussusception; oncologic surgical pathology; urologic surgical pathology. Optional topics: surgical pathology of congenital malformations that can be cured with surgery; surgical gastroenterologic pathologies; acute abdominal pain; Wilms; rhabdomyosarcoma; teratomas; hepatoblastoma; hydronephrosis; vesicoureteral reflux; renal dysplasia and renal cysts. Neuropsychiatry - Very important topics: neuropsychological child’s development; cerebral palsy; epilepsies; convulsions; learning disabilities; neuromuscular disorders; psychosis; neurosis; psychosomatic disorders; support to the child and child’s family. RECOMMENDED BOOKS G.R. Burgio, G. Perinotto, A.G. Ugazio, Pediatria Essenziale, 4 ed. UTET. Dispensa di Neuropsichiatria, La Goliardica Pavese G. Verga, G.B.Parigi, Chir. Pediatrica in Chirurgia, R. Dionigi Masson 1° edizione GYNAECOLOGY AND OBSTETRICS Coordinator C. Zara Unit Ginecologia e Ostetricia Teacher C. Zara Unit Fisiopatologia della Riproduzione Human Teacher F. Polatti Unit Ginecologia Oncologica Teacher P. Sanpaolo Unit Medicina dell’età prenatale Teacher L. Montanari Interactive exercitation A. Spinillo, R. Nappi, F. Beneventi, F. Ravagni teachers AIMS Gynaecology and obstetrics: The goal is to become able to recognize the most important obstetric and gynaecological pathologies and to formulate the diagnosis through anamnesis, medical examination, and interpretation of laboratory tests and imaging results. Students must learn how to help the specialist in the treatment of the most complicated gynaecological pathologies and must be able to recognize promptly symptoms and clinical features of obstetric emergencies. Physiopathology of reproduction: The goal is to give the elements to correctly evaluate the physiology and pathology of the menstrual cycle and to become familiar with problems related to sterility, contraception, and climacterium. Gynaecological oncology: The aim is to give information about the epidemiology and risk factors of genital malignancies and breast cancer and to explain the methods used to obtain an early diagnosis of malignancy. The second aim is to teach how to treat the gynaecological neoplasms in all the different localizations. Prenatal age medicine: The goal is to become able to supervise pregnancy, delivery, and puerperium. The study of the embryofoetal wellbeing and the knowledge about the different methods to underline it are included in the lessons of prenatal age medicine. . TOPICS Gynaecology and obstetrics • Medical and surgical pathologies in pregnancy • HIV infection and reproduction • TORCH group related pathologies • Third trimester methrorrhagies • Obstetric emergencies in the first 90 days of pregnancy • Obstetric emergencies in the second and third trimester of pregnancy • Oncologic pathology and pregnancy • Directions for physiologic delivery • Oncologic risk and hormonal therapy • Discharge of the afterbirth and puerperium related pathologies • Clinical cases Prenatal age medicine • Physiology of pregnancy • Physiology and pathology of the amniotic fluid • Twin pregnancy • Physiologic delivery and physiologic puerperium • Lactation • Drugs in pregnancy and lactation • Natural abortion • • • • • • Law number 194 Prenatal diagnosis Foetal malformations Preterm and after term births PROM Clinical cases Human reproduction physiopathology • Anatomy and physiology of the female apparatus • Gametogenesis • Fertilization • Nidation • Embryogenesis • Steroidogenesis • Hypothalamus hypophysis ovary axis • Gonads differentiation and Mullerian system differentiation • Sterility • Climacterium • Contraception • Fibromas, endometriosis and benign pelvic masses • Dysfunctional meno-methrorrhagies • PID • Sexually transmitted diseases • Genital prolapse • Pelvic pain • Vulvar benign pathology • Clinical cases Gynaecological oncology • Prevention, diagnosis and therapy in gynaecological oncology: portio carcinoma, endometrium carcinoma, and ovarian cancer • Vulvar and vaginal neoplasms • Uterine sarcomas • Benign and malignant mammary pathology • Trophoblastic pathology • Follow-up of gynaecological diseases • Clinical cases RECOMMENDED BOOKS Pescetto, DeCecco, Pecorari, Manuale di Ginecologia e Ostetricia, SEU ed. Candiani, Danesino, Gastaldi, La Clinica Ginecoloca e Ostetrica, MASSON ed. Thomas Rabe, Ginecologia e Ostetricia, CIC ed. Work Medicine coordinatore: modulo: docenti modulo: docenti modulo: docenti A. Cavalleri Work Medicine A. Cavalleri, S. Candura, M. Imbriani Working Preventive Medicine and Psychotechnique A. Cavalleri, E. Crovato Industrial Hygiene M. R. Re, G. Catenacci The aim of the course is: • to teach the essential elements to identify and quantify risk factors in working along with the methodologies of prevention of these risks. • To illustrate nosographic frames of the most relevant professional diseases, underlining the aetiopathogenesis of the technopathies. • To delineate the epidemiology techniques in work medicine • To comment the main laws of work hygiene, underlining the related obligations for healthcare professionals. Main contents: Generality, definitions and aims of work medicine;technologic approach. Pathologies derived from toxic agents closeness; working anamnesis. Ethical and forensic outcomes of the lack of professional disease diagnosis; primary and secondary prevention; environmental and biological monitoring. Validity of the tests; effect and absorption indicators; professional risk assessment; pathologies caused by noise and electricity; pathologies from vibrations; the microclimate and its effects; pathology from ionized and nonionized radiations; professional pneumoconiosis and BPCO (broncopulmonary chronic obstructive disease); absorption, biotransformation, excretion of the xenobiotics; pathology from metals; extrinsic allergic alveolitis, professional bronchial asthma; pathology from industrial dissolvents; “oxycarbonism” and methods to measure the HbCO; elements of industrial hygiene; importance of biological monitoring to prevent professional risks; quali-quantitative determination of the chemical and physical factors of risk; location of the factors of risk in some industrial technologies; professional dermopathies; the effects of the most important pesticides; neoplastic pathologies of professional origin; the neoplasms of professional origin; notions of ergonomics and pathologies derived from physical charge; notions of work legislation and most important laws to be known by healthcare professionals. Program of the oral exam: • • • • • • • • • • • • Work medicine and prevention of the professional diseases: introduction and principles Pathology of the respiratory ways Industrial toxicology (e.g. metals: chromium, lead, mercury, cadmium) Pathology from radiation (ionized and nonionized) Pathology from dissolvents Cancerogenous substances Work and osteoarticular pathologies Sanitary surveillance for VDT Biological monitoring of the professional exposure: principles, methods, applications Principles of Hygiene of the job Risk factors derived from the working environment, and limit values of exposure. Methodologies of biologic and environmental monitoring: technical and forensic aspects Obligation of report and denunciation of professional disease 2ND TERM INTERNAL MEDICINE Coordinator Unit Teachers Interactive exercitation teachers R. Fogari Internal Medicine E. Ascari, Balduini, R. Fogari E. Marchesi, P. Gobbi, S. Perlini, R. Invernizzi Aims: Students must be able to integrate symptoms, signs and structural and functional alterations to globally evaluate the health situation of a single adult patient with reference to the preventive, diagnostic, prognostic and therapeutic aspects. Students must be able to analyze and solve clinical problems concerning internal medicine by the diagnostic and therapeutic point of view, evaluating the risks and the risk-benefit ratio of the therapeutic interventions. Topics; Presentation and discussion of clinical cases of different diseases: haematologic, gastroenterologic, oncologic, cardiovascular, pulmonary, hepatic, renal, metabolic and endocrine. Medical genetics and ereditary pathologies problems. Treatment of infectious, digestive, hepatic, renal diseases; treatment of malignant neoplasia, cardiovascular diseases, haemopathies, nephropaties and so on. GENERAL SURGERY coordinator Unit Teachers E. Forni GENERAL SURGERY E. Forni, F. Meriggi Targets: The student must be able to aggregate symptoms, signs, structural and functional impairments in a preventive, diagnostic, prognostic, therapeutic, rehabilitative appraisal of the global health status of the adult or elderly patient; analyse and solve clinical problems of surgical and oncological interest considering the patient status, the disease severity, benefit, risk and cost ratio expected by the medical treatment. Topics: surgical pathology of the chest A) Mediastinum: mediastinitis, mediastinic masses, mediastinic syndrome; B) Lung and Pleura: non TBC pleural empyema, benign and malignant tumours, endocrine paraneoplastic syndromes, pleural and lung injury; C) Esophagus: diverticula, functional disease, (diskinesia, cardias achalasia, dilatations of esophagus) esophagitis by caustic ingest, GERD, paraesophageal hernia, benign and malignant tumors; D) Diaphragm: injury, posttraumatic hernia. Surgical pathology of abdomen: A) Stomach: ulcerous disease of surgical interest, benign and malignant tumours; B) Small intestine and colon: ischaemic disease, diverticular disease, inflammatory chronic disease (Crohn’s disease, Ulcerative colitis), benign and malignant tumours; C) Anus: benign pathology (haemorrhoids, fissures, suppurations, fistula) benign and malignant tumors; D) Surgical problems in portal hypertension E) Hepatic lesions: diagnoses and therapy F) surgical treatment of acute hepatitis G) Intra and extra-hepatic biliary tract: cistic pathology, gallstone disease, benign and malignant strictures; H) Pancreas: injury, acute and chronic pancreatitis I) Basics of laparoscopic and mini-invasive surgery. RECOMMENDED BOOKS: Dionigi R., Chirurgia, Ed. Masson Colombo C, Paletto AE, Trattato di Chirurgia, Ed Minerva Davis-Christopher, Sabiston, Textbook of Surgery, Ed. WB Saunders MEDICAL-SURGICAL EMERGENCIES G. Ricevuti Coordinator: Unit: Emergency Medicine Teachers G. Ricevuti Unit: Emergency surgery Teachers L. Bonandrini Unit: Intensive therapy Teachers A. Braschi Targets: First aid and emergency rescue: Students must learn how to approach acute problems of patients with most common disease of internal medicine. They should plan a diagnostic iter considering evidence-based medicine and the cost analysis of the tests; to understand the results of the clinical and instrumental tests in order to make differential diagnosis and afterward decide a therapeutic, drug based, strategy for the acute stage of the disease. The students have to know the prevention for main common diseases and the importance of day by day refresh with scientific literature and guidelines. The course is based on different kind of lessons (ex cathedra, seminars) and practice activity in wards. Surgical critical care: students must be able to treat surgical emergency in the emergency ward. They have to recognize internal and external haemorrhage, make differential diagnosis and diagnostic flow chart of abdominal pain; to be able to treat the acute trauma and to attend to bladder catheter setting, endoscopic haemostasis of bleeding lesions, laparoscopic surgery in emergency, paracentesis, thoracentesis, instrumental diagnosis, laparotomy, thoracotomy, cervicotomy; estimate the trauma score for the main chest and abdominal lesions. Skin wound suture and their removal, wound prophylaxis and care. Intensive Therapy: Student must be able to treat an emergency in intensive therapy. They must assess the shocked patient and be able to do differential diagnosis and diagnostic flow-chart of pain. They must know basic notions of general anaesthesia, different type of anaesthesia and related complications. The student have to attend to different steps of patient preparation for a general anaesthesia, to a local, subarachnoid and peridural anaesthesia. The students have to know severe dyspnoea treatment, hyperbaric oxygen therapy, artificial ventilation, first aid in coma, drowning, burns, electric shock. Topics:Emergency and first aid: Principles of general physiopathology; chest pain and related syndromes; cardiopulmonary resuscitation; acute myocardial infarction: how to face the emergency, prevention and treatment of complications; arrhythmias: how to diagnose by symptoms and ECG, drug and instrumental treatment; temporary and permanent defibrillator; sudden death, prevention and treatment; hypertension-related emergency; acute heart failure; aortic dissection; physiopathology of sepsis: septicaemia and treatment of infectious disease, exanthema and fever; lung embolism; seriously burnt patient; nuclear emergency; heart emergency; lung and breath emergency; gastrointestinal emergency (diarrhoea, constipation, haemorrhage); endocrine and metabolic emergency (diabetic and endocrine coma, thyreotossicosis, neuroendocrine emergency, electrolytic alteration); neurological emergency and consciuosness alteration; haematologic emergency (acute haemorrhage, thrombosis, neutropenia); toxicological emergency; psychiatric emergency; neoplastic emergency; organs reject; ABE alterations; kidney disease(i.e. acute kidney failure, kidney stone); the “crush syndrome”; general knowledges about: burns, tetanus, drowning, poisoning, ictus cerebri; haemorrhagic and thrombophylic diseases; syncope; diagnosis and treatment of coma; emergency drugs; the triage; portal hypertension. Surgical emergency and first aid: bowel ischaemia: physiopathology, diagnosis, surgical treatment, the second look; acute appendicitis and its complications; surgical jaundice: diagnosis, treatment; acute pancreatitis: different types, complications; acute limb embolism and thrombosis: physiopathology, diagnosis, treatment; acute Meckel’s diverticula disease; abdomen traumas (liver, spleen, bowel, kidney, pancreas traumas); chest traumas; limbs traumas, diagnosis and different treatments; politraumas; acute abdomen syndrome, definition, symptoms, diagnosis and treatment; acute complications of gastroduodenal peptic disease: haemorrhage, perforation, stenosis; bowel obstruction: classification, symptoms, diagnosis, medical and surgical treatment, 12-3 times surgical treatment; hernial strangling, physiopathology, symptoms, taxis manoeuvre, surgical treatment; acute diffuse and circumscribed peritonitis, physiopathology, diagnosis, treatment; digestive haemorrhage. Intensive treatment: general principles of anaesthesia and analgesia; how to prepare patient to a surgical treatment; anaesthesia drugs; analgesics; general and local anaesthesia techniques; cervical, brachial, lumbar, sacral plexus anaesthesia; emergency anaesthesia techniques; anaesthesia equipment; most important anaesthesia complications; acute pain treatment; chronic non-neoplastic pain, diagnosis and treatment; neoplastic pain; drugs and techniques of analgesia; the pain clinics; shock, definition, classification, physiopathology, treatment; breathing reanimation, acute lung failure; breathing assistance techniques; nutrition bearing; ABE; electrolytic balance; infections in intensive treatment, antibiotic treatment; transfusions; most important metabolic troubles; post-surgical treatment pain treatment; Multi Organ Failure syndrome. RECOMMENDED AA. Vari, Manuale di Emergenze Medicochirurgiche, ed. UTET Torino, Lit. BOOKS 70.000. ZANNINI G., Chirurgia General, ed. UTET, Torino, 1995, Lit. 298.000. CORAGGIO F., Medicina d'Urgenza e di Pronto Soccorso, ed. Idelson, Napoli, Lit 380.000. MAZZARELLA B., MASTRONARDI P., Manuale di anestesia e Rianimazione, ed. Piccin, Padova, 1995, Lit. 50.000. JOVINO R. ED ALTRI AA, Chirurgia D’Urgenza, Ed. PICCIN, Padova 1981, Lit. 250.000. AA.VV., trad. ed adatt. di D. Lombardi, Traumatologia, ediz. EDISES Napoli 1998, Lit. 90.000 circa. TIBERIO G., RANDAZZO A., GATTINONI L., ANDREONI B.: Emergenze MedicoChirurgiche. Ed. Masson, seconda edizione, 2000. Emergenze medicochirurgiche (Ed. UTET 1998) Current Emergency Medicine (Ed. LANGE 1998) Guida illustrata alle emergenze (Ed. PICCIN 1999) Emergenze medicochirurgiche (Ed. MASSON 2000) Manuale di Medicina d’Emergenza (Ed. MC.GRAWHILL 2001) Manuale di Medicina di Emergenza F. Della Corte, F. Olliveri, F. Enrichens Edito Mc Graw Hill, 2002 FORENSIC MEDICINE F. Buzzi Coordinator: Unit: Forensic Medicine Teachers F. Buzzi Unit: Forensic Toxicology Teachers M. Montagna, A. Polettini Unit: Forensic Psychopathology Teachers Luzzago Unit: Social Medicine Teachers P. Danesino Aims: knowledge of the legal setting of the health professions, in particular of the medical profession with reference to the state system, the deontological rules, and the patients rights. Knowledge of the legal duties and of the prohibitions involving doctors, knowledge of the information duties towards the legal authority (report) and the administrative and sanitary authority (denunciation and professional secret) and the citizen authority (social and private insurances; protection of disability and handicaps). Knowledge of the principal offending processes (forensic pathology and toxicology) and of the cadaverous phenomena (thanatology). Knowledge of the problem of organs explantation for transplantations; knowledge of the problem of voluntary pregnancy interruption and of conscientious objection, and of sexual crimes. Knowledge of the rules concerning life and safety protection (individual and collective). Knowledge of the legal features of euthanasia, psychic disabilities and drug addictions. Knowledge of the topics about the doctors professional fault (individual responsibility and group responsibility) and of the related civil and penal consequences. TOPICS: Legal medicine as a branch of public medicine and as a legal projection of medico-biological sciences. Crimes against persons: strokes, personal injuries, different types of homicide. The poison as a productive tool of legally relevant damages. Principal poisonings treated in diagnostic and medicolegal optics. Forensic psychopathology in the civil law sphere: compulsory sanitary treatments. Sanitary arts and professions. Health and the article 32 of the Constitution. Tanathology: the cadaverous phenomena. Certification in case of death. Autopsy and diagnostic checks. Drugs and drugs addictions: legislative and toxicological-forensic features. Drugs related deaths. Alcohol and drunkenness with reference to the problems related to imputability, disability and driving. Children abuse. Sexual violence. Forensic psychiatry in the penal law sphere. Protection of mental disable persons and crimes victims children. Legal duties of doctors. Medicolegal traumatic pathology. Asphyxiology and others. Causality: medicolegal criteriology. Professional fault, the deontological code. Essentials of penitentiary medicine. Abortion and voluntary interruption of pregnancy. Assisted insemination. Terminal states, anticipated directives, palliative care, assisted suicide and euthanasia. Expert opinion and expert’s report in the penal law sphere. Expert opinion in the civil law sphere. 6th YEAR’S OPTIONAL ACTIVITES (ATTIVITÀ di DIDATTICA OPZIONALE: A.D.E.) Optional Course Title Monographic courses: 10 CFU Integrated Course Responsible Chirurgia miniinvasiva videoassistita Chirurgia generale Forni E. La terapia ormonale in ginecologia Ginecologia ed ostetricia Zara C. Elementi di epidemiologia occupazionale Medicina del lavoro Candura S. Valutazione dei fattori di rischio in ambito professionale Medicina del lavoro Candura S. Moderni orientamenti nel trattamento chirurgico delle neoplasie ginecologiche Ginecologia ed ostetricia Zara C. Casistica clinica Emergenze Medico Chirurgiche Ricevuti G. L’incidente stradale: cause, prevenzione, lesioni, postumi Medicina legale Buzzi F. Corso Teorico Pratico di BLS Emergenze Medico Chirurgiche Ricevuti G. Terapia del Dolore Emergenze Medico Chirurgiche Braschi A. Corso monografico di area medica Collegio Universitario Coordinatore Internship: 30 CFU Optional Course Title Internship of General Surgery Integrated Course General Surgery Responsible Forni E. Internship of General Surgery General Surgery Dionigi P. Internship of Internal Medicine Internal Medicine Fogari R. Internship of Internal Medicine Internal Medicine Balduini C. Internship of Work Medicine Work Medicine Cavalleri A. Candura S. Internship of Obstetrics and Gynaecology Obstetrics and Gynaecology Zara C., F. Polatti Internship Internship Internship Internship Internship Forensic Medicine Paediatrics Medical Surgical Emergencies Medical Surgical Emergencies Emergenze Medico Chirurgiche Pierucci G., F. Buzzi Rondini G. Ricevuti G. Braschi Ricevuti G. of of of of of Forensic Medicine Paediatrics Emergency Medicine Emergency Medicine - BLS Family Medicine USEFUL INFORMATION AND ADDRESSES Preside della Facoltà di Medicina e Chirurgia Prof. Alberto Calligaro Dip. di Medicina Preventiva, Sezione di Istologia, Via Forlanini, 10 – 27100 Pavia, tel. +39-0382 – 987272 Presidente del Corso di Laurea in Medicina e Chirurgia Prof. Maria Scappaticci Dip. di Patologia Umana ed Ereditaria, Sezione di Biologia e Genetica, Via Forlanini, 14 – 27100 Pavia, tel. +39-0382 – 987721/987731 Segreteria di Presidenza Piazzale Volontari del Sangue, [email protected] 2 – 27100 Pavia, tel. +39-0382- 527053/527147. DIPARTIMENTI Alla Facoltà di Medicina e Chirurgia afferiscono i seguenti Dipartimenti: BIOCHIMICA – Via Taramelli, 3/B – Sezione di Medicina – Via Taramelli, 3/B – tel. +39-0382 987223 Direzione: tel. +39-0382 987787 Segreteria: tel. +39-0382 987223 Fax: +39-0382 423108 Sezione di Analisi Chimico Cliniche – c/o Ospedale S.Matteo – tel. +39-0382 423251 Direzione: tel. +39-0382 423251 Sezione di Scienze – via Bassi, 21 Tel. +39-0382 987236 – fax +39-0382 987240 CHIRURGIA - Via Aselli, 25 Centralino – tel. +39-0382 987560 Segreteria: tel. +39-0382 987561 – 987586 Fax : +39-0382 423504 Sezione di Chirurgica Generale “A” – c/o Policlinico S. Matteo Direzione: tel. +39-0382 526214 – 502530 – 987585 Segreteria: tel. +39-0382 502589 – 502490 Fax: +39-0382 502999 Lab. di Chirurgia Sperimentale – Piazza Botta, 10 Centralino e Fax: +39-0382 506400 Sezione di Clinica Neurochirurgica – c/o Policlinico S. Matteo Direzione: tel. +39-0382 422231 Segreteria: tel. +39-0382 422231 – 502780 Fax: +39-0382 422231 Sezione Terapia e Riabilitazione Organi del Movimento – c/o Policlinico S. Matteo Direzione: tel. +39-0382 502829 Segreteria: tel. +39-0382 502083 Fax +39-0382 528495 Sezione Chirurgia Plastica – Via Aselli, 45 Direzione: tel. +39-0382 526091 Fax: +39-0382 +39-0382 423504 SCIENZE EMATOLOGICHE PNEUMOLOGICHE CARDIOVASCOLARI Sezione di Chirurgia Vascolare – c/o Policlinico S. Matteo Direzione: tel. +39-0382 527959 Segreteria: tel. +39-0382 527959 Fax +39-0382 527959 Sezione di Ematologia – c/o Policlinico S. Matteo Direzione: tel. +39-0382 501284 Segreteria: tel. +39-0382 503595 Fax: +39-0382 502250 Sezione di Cardiologia – c/o Policlinico S. Matteo Direzione: tel. +39-0382 503673 Segreteria: tel. +39-0382 526061 Fax: +39-0382 503002 Sezione Clinica Tisiologica e Malattie Apparato Respiratorio – c/o Policlinico S. Matteo Direzione e Segreteria: tel. +39-0382 422232 Cattedra di Chemioterapia : tel. +39-0382 422232 MEDICINA INTERNA E TERAPIA MEDICA – Piazza Botta n. 10 Segreteria Dipartimento: tel. +39-0382 986355-6 Fax: +39-0382 22741 Sezione di Medicina Interna, Malattie Vascolari e Metaboliche c/o Policlinico San Matteo Clinica Medica II’ Tel.: +39-0382/526217 Fax: +39-0382 526897 Sezione di Medicina Interna ed Oncologia c/o Policlinico San Matteo Clinica Medica I’ Tel.: +39-0382 526284 Fax: +39-0382 526223 Sezione di Nefrologia c/o Policlinico San Matteo Reparti Speciali [email protected] Tel.: +39-0382 422037 Fax: +39-0382 526341 Sezione di Farmacologia Clinica e Sperimentale Piazza Botta n. 10 Tel.: +39-0382 986353 Fax: +39-0382 986419 Sezione di Gerontologia e Geriatria c/o Istituto Santa Margherita Piazza Borromeo [email protected] Tel.: +39-0382 27769 Fax: +39-0382 28827 Sezione di Gastroenterologia C/o Policlinico San Matteo Palazzina Clinica Medica Tel.: +39-0382 502973-4 Fax: +39-0382 502618 Sezione di Farmacologia e Tossicologia Cellulare e Molecolare Piazza Botta n. 10 Tel.: +39-0382 986343 Fax: +39-0382 28426 Sezione di Reumatologia e Tossicologia Clinica C/o Fondazione Maugeri Tel.: +39-0382 592780 Centro Interdipartimentale di Bioetica Medica Direzione:tel. +39-0382 986367 Fax: +39-0382 22741 Dipartimenti afferenti: Medicina Interna e Terapia Medica Patologia Human ed Ereditaria Medicina Legale e Sanità Pubblica MEDICINA PREVENTIVA OCCUPAZIONALE E DI COMUNITA’ - Via S. Boezio, 24 Segreteria e Direzione: tel. +39-0382 35442 – 593796 Fax: +39-0382 303987 Segreteria amministrativa: tel. +39-0382 987276 Sezione di Igiene – Via Forlanini, 2 Direzione: tel. +39-0382 987277 Segreteria: tel +39-0382 987289 Fax: +39-0382 987558 Centro di Ecologia Umana: tel +39-0382 526277 Centro Antidiabetico: tel. +39-0382 526234 Sezione di Medicina del Lavoro – Via S. Boezio, 24 Segreteria e Direzione: tel. +39-0382 592255 Fax: +39-0382 33534 Sezione di Medicina del Lavoro II e Medicina Preventiva dei Lavoratori Via S. Boezio, 24 Segreteria e Direzione: tel. +39-0382 35442 - 593796 Fax: +39-0382 303987 Centro malattie Cardiovascolari Professionali Segreteria: tel. +39-0382 35442 Centro Ricerche Fisiopatologia e Sicurezza del Lavoro ed Ergonomia Segreteria: tel. +39-0382 35442 Centro Studi di Ricerche di Tossicologia Industriale Segreteria: tel. +39-0382 303506 Centro Studi e Ricerche nell’Oncologia Professionale Segreteria: tel. +39-0382 35442 Centro Interuniversitario di Ricerca di Medicina Preventiva dei Lavoratori Segreteria: tel. +39-0382 35442 PATOLOGIA UMANA ED EREDITARIA – Via Forlanini, 14 Segreteria amministrativa: tel. +39-0382 987729 Sezione di Anatomia Patologica – Via Forlanini, 16 Segreteria: tel. +39-0382 528474 – 528475 – 528476 – 528476 Fax +39-0382 +39-0382 525866 Sezione di Biology General e Genetics Medica – Via Forlanini, 14 Segreteria: tel. +39-0382 987521 Fax +39-0382 525030 Sezione di Clinica Dermatologica – c/o Policlinico S. Matteo, Piazzale Golgi, 2 Direzione: tel. +39-0382 528451 II Cattedra: tel. +39-0382 527953 Fax +39-0382 526379 SCIENZE SANITARIE APPLICATE E PSICOCOMPORTAMENTALI – Via Bassi, 21 Segreteria Amministrativa: tel. +39-0382 987640 fax. +39-0382/987570 E-mail: [email protected] Portineria +39-0382 987538 Sezione Biometria e Statistica Medica Direzione – segreteria: tel. +39-0382 987537 E-mail: [email protected] Sezione di Psichiatria Direzione – segreteria: tel. +39-0382 987250 E-mail: [email protected] Segreteria studenti: tel. 0383 987246 fax. +39-0382 526723 Sezione Scienze dell’Alimentazione Direzione – segreteria: tel. +39-0382 987881 E-mail: [email protected] Centro Studi e Ricerche sulla Nutrizione Umana e i Disturbi del Comportamento Alimentale Direzione – segreteria: tel. +39-0382 987842 Centro Interdipartimentale di Studi e Ricerche sulla Sicurezza Stradale (CIRSS) Direzione – segreteria: tel. +39-0382 987537 Centro Interdipartimentaledi Studi sulla Sicurezza e Qualità degli Alimenti (CISQUA) Direzione – segreteria: tel. +39-0382 987881 Centro Interdipartimentale sui Disturbi della Personalità e sullo Sviluppo dei Modelli di Comunicazione Medico-Paziente (CIRDIP) Direzione – segreteria: tel. +39-0382 5078422 SCIENZE MORFOLOGICHE, EIDOLOGICHE E CLINICHE – Via Brambilla, 74 Segreteria amministrativa: tel. +39-0382 523959 Fax: +39-0382 529938 Sezione di MicroBiology – Via Brambilla, 74 Centralino: tel. +39-0382 548411 Informazioni: tel. +39-0382 5484201 Segreteria: tel. +39-0382 5484202 Direzione: tel. +39-0382 54842 Sezione di Clinica Ostetrica Ginecologica – c/o Policlinico S. Matteo Direzione: tel. +39-0382 526270 Segreteria: tel. +39-0382 526215 Fax: +39-0382 423233 Cattedra di Fisiopatologia della Riproduzione Human: tel. +39-0382 422591 Patologia Ostetrica e Ginecologica: tel. +39-0382 527974 Sezione di Radiologia – c/o Policlinico S. Matteo Direzione: tel. +39-0382 526257 Segreteria: tel. +39-0382 525725 Fax: +39-0382 527970 Sezione Clinica Ortopedica e Traumatologica – c/o Policlinico S. Matteo Direzione: tel. +39-0382 526294 Segreteria: tel. +39-0382 526375 – 502852 Fax: +39-0382 526319 Sezione Clinica Malattie Infettive e Tropicali – c/o Policlinico S. Matteo Direzione: tel. +39-0382 502674 Segreteria: tel. +39-0382 502691 Fax: +39-0382 529730 MEDICINA LEGALE E SANITA’ PUBBLICA – Via Forlanini, 12 Centralino: tel. +39-0382 987800 Fax: +39-0382 528025 Segreteria amministrativa: tel. +39-0382 987830 – 987824 Segreteria direzione: tel. +39-0382 987822 SCIENZE NEUROLOGICHE – c/o Fondazione C. Mondino, Via Palestro, 3 Centralino: tel. +39-0382 3801 Fax: +39-0382 26522 Direzione: tel. +39-0382/25001 Segreteria studenti: +39-0382/380203/380291 Segreteria amministrativa: tel. +39-0382 380281 Fax+39-0382/26522 SCIENZE PEDIATRICHE – c/o Policlinico S. Matteo Direzione: tel. +39-0382 529062 – 526228 Segreteria: tel. 0282 526269 – 502891 – 502898 Segreteria amministrativa: tel. +39-0382 502906 Fax: +39-0382 527976 MEDICINA SPERIMENTALE Direzione: tel. +39-0382 506332 Segreteria amministrativa: tel. +39-0382 506333 Sezione di Patologia General “C. Golgi” – Piazza Botta, 10 Direzione: tel. +39-0382 506332 Segreteria: tel. +39-0382 506333 Portineria: tel. 506331 Fax: +39-0382 303673 Sezione di Istologia ed Embriologia Generale – Via Forlanini, 10 Centralino: tel. +39-0382 987272 Direzione: tel. +39-0382 987273 Segreteria: tel. +39-0382 987755 Fax: +39-0382 528330 Sezione di Anatomia Umana Normale – Via Forlanini, 8 Direzione: tel. +39-0382 987645 Segreteria: tel. +39-0382 987647 Fax: +39-0382 422117 Presidenza e Segreteria del Corso di Laurea in Scienze Motorie Segreteria: tel. +39-0382 987646 Sezione di Fisiologia Umana – Via Forlanini, 6 Direzione: tel. +39-0382 987518 Segreteria: tel. +39-0382 987518 Fax: +39-0382 987664 DISCIPLINE ODONTOSTOMATOLOGICHE “SILVIO PALAZZI” Direzione: tel. +39-0382 526283 Segreteria: tel. +39-0382 526221 Fax: +39-0382 423029 Presidente del C.L.O.P.D.: tel e fax +39-0382 423516 Sez. Didattica C.L.O.P.D., Viale Brambilla, 74, tel. +39-0382 529603 MALATTIE INFETTIVE Segreteria amministrativa: tel. +39-0382 502670 Direzione: tel. +39-0382 502661 – 502669 Segreteria: tel. +39-0382422030 – 502661 Fax: +39-0382 423320 CHIRURGIA GENERALE E DEI TRAPIANTI D’ORGANO Direzione: tel. +39-0382 526216 Segreteria: tel. +39-0382 +39-0382 502519 , Fax +39-0382 528335 SCIENZE SENSORIALI Sezione Clinica Oculistica Direzione e segreteria: tel. +39-0382 526213 Fax: +39-0382 527006 Sezione Clinica Otorinolaringoiatria Direzione: tel. +39-0382 526239 Segreteria: tel. +39-0382 526218 POST-DEGREE SCHOOLS OF SPECIALIZATION Allergologia ed immunologia clinica Director: prof. Francesco Candura Location: Sez. Medicina del Lavoro - Via S. Boezio, 24 Tel. +39-+39-0382 592255 Durata: anni 4 Anatomia Patologica Director: prof. Enrico Solcia Location: Dip. di Patologia Human ed Ereditaria - Sez. di Anatomia e Histology Patologica - Via Forlanini ,14 Tel. +39-+39-0382 503612/502517 Durata: anni 5 Anestesia e Rianimazione Director: prof. Antonio Braschi Location: Serv. Anestesia e Rianimazione 1 - Dip. di Chirurgia– Policlinico S.Matteo Piazza Golgi, 2 Tel: +39-+39-0382 503477 Durata: anni 4 Biochemistry clinica Director: prof. Remigio Moratti Location: Dipartimento di Biochemistry - Viale Taramelli, 3b Tel: +39-+39-0382 987226 Durata: anni 4 Cardiochirurgia Director: prof. Mario Viganò Location: Clinica Chirurgica – Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 503515 Durata: anni 5 Cardiologia Director: prof. Peter Schwartz Location: Divisione di Cardiologia - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526061 Durata: anni 4 Chirurgia Generale I– Indirizzo Chirurgia Generale Director: prof.Eugenio Forni Location: Clinica Chirurgica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 502519 Durata: anni 6 Chirurgia Generale II - Indirizzo Chirurgia d’Urgenza Director: prof. Paolo Dionigi Location: Sezione di Chirurgia Generale - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 502589 Durata: anni 6 Chirurgia Generale III – Indirizzo Chirurgia d’Urgenza Director: prof. Luigi Bonandrini Location: Dipartimento di Chirurgia Tel: +39-+39-0382 433666 Durata anni 6 Chirurgia Pediatrica Director: prof. Location: Chirurgia Pediatrica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 422966 5 Years Chirurgia Plastica e Ricostruttiva Director: prof. Angela Faga Location: Dip.di Chirurgia - Via Aselli, 45 Tel: +39-+39-0382 526091 Durata: anni 5 Chirurgia Toracica Director: prof. Eugenio Forni Location: Clinica Chirurgica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 502519 Durata: anni 5 Chirurgia Vascolare Director: prof. Attilio Odero Location: Sezione di Chirurgia Vascolare - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 527959 Durata: anni 5 Dermatologia e Venereologia Director: prof. Giovanni Borroni Location: Clinica Dermatologica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 528451 Durata: anni 4 Ematologia Director: prof. Mario Lazzarino Location: Sez. di Ematologia - Policlinico San Matteo - Piazzale Golgi,2 Tel: +39-+39-0382 503595 Durata: anni 4 Endocrinologia e Malattie del Ricambio Director: prof. Ettore Ferrari Location: Sez. di Geriatria, presso Istituto Santa Margherita - P.zza Borromeo, 2 Tel: +39-+39-0382 27769 – Fax +39-+39-0382 28827 Durata: anni 5 Farmacologia Director: prof. Gianmario Frigo Location: Sez. di Farmacologia clinica e sperimentale- P.zza Botta, 10 Tel: +39-+39-0382 506357/506353 Durata: anni 4 Gastroenterologia Director: prof. Gino Roberto Corazza Location: Clinica Medica I - Cattedra ed unità operativa di gastroenterologia, Policlinico San Matteo – Piazzale Golgi, 2 Tel: +39-+39-0382 502973/4 Durata: anni 4 Genetica Medica Director: prof. Orsetta Zuffardi Location: Istituto di Biology Generale – Via Forlanini,14 Tel: +39-+39-0382 987733 Durata: anni 4 Geriatria Director: prof. Ettore Ferrari Location: Sez.di Geriatria presso Istituto Santa Margherita - P.zza Borromeo,2 Tel: +39-+39-0382 27769 – Fax +39-+39-0382 28827 Durata: anni 4 Ginecologia ed Ostetricia Director: prof. Carlo Zara Location: Clinica Ostetrica e Ginecologica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526215 Durata: anni 5 Hygiene e Medicina Preventiva Director: prof. Cesare Meloni Location: Dip. di Medicina Preventiva Occupazionale e di Comunità - Sez. di Hygiene - Via Forlanini,1 Tel: +39-+39-0382 987289 Durata: anni 4 Malattie dell’Apparato Respiratorio Director: prof. Ernesto Pozzi Location: Clinica di Malattie dell’Apparato Respiratorio - Policlinico San Matteo – Piazzale Golgi, 2 Tel: +39-+39-0382 422232 Durata: anni 4 Malattie Infettive Director: prof. Lorenzo Minoli Location: Dipartimento di Malattie Infettive - Policlinico San Matteo – Piazzale Golgi, 2 Tel: +39-+39-0382 502661 Durata: anni 4 Medicina del Lavoro I Director: prof. Stefano Candura Location: Sezione di Medicina del Lavoro - Via Boezio, 24 Tel: +39-+39-0382 592255 Durata: anni 4 Medicina del Lavoro II Director: prof. Alessandro Cavalleri Location: Sez. di Medicina del Lavoro II e Medicina Preventiva dei lavoratori – Via Boezio, 24 Tel: +39-+39-0382 35442 Durata: anni 4 Medicina dello Sport Director: prof. Roberto Bottinelli Location: Istituto di Physiology Human - Via Forlanini, 6 Tel: +39-+39-0382 987518 Durata: anni 4 Medicina Fisica e Riabilitazione Director: prof. Elena Dalla Toffola Location: Sez. di Terapia e Riabilitazione degli organi del movimento - Policlinico San Matteo – Piazzale Golgi, 2 Tel: +39-+39-0382 502083 Durata: anni 4 Medicina Interna Director: prof. Roberto Fogari Location: Sez. Medicina Interna e Oncologia Medica- Policlinico S. Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526284/502580 Durata: anni 5 Medicina Legale Director: prof. Fabio Buzzi Location: Dip. di Medicina Legale e Sanità Pubblica - Via Forlanini, 12 Tel: +39-+39-0382 987284 Durata: anni 4 Medicina Tropicale Director: prof. Gaetano Filice Location: Clinica Malattie Infettive e Tropicali - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 502674 Durata: anni 4 Microbiologia e Virologia Director: prof. Laura Pagani Location: Dip. di Scienze Morfologiche, Eidologiche e Cliniche – Via Brambilla 74 Tel: +39-+39-0382 526335 Durata: anni 4 Nefrologia Director: prof. Antonio Dal Canton Location: Dipartimento di Medicina Interna e Nefrologia - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 422037 Durata: anni 5 Neurochirurgia Director: prof.Cesare Arienta Location: Clinica Neurochirurgica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 422231 - 502780 Durata: anni 5 Neurofisiopatologia Director: prof. Vittorio Cosi Location: Dip. di Scienze Neurologiche - Via Palestro, 3 Tel: +39-+39-0382 380208/380291 Fax: +39-+39-0382 24714 Durata: anni 4 Neurologia Director: prof Vittorio Cosi Location: Dip. di Scienze Neurologiche - Via Palestro, 3 Tel: +39-+39-0382 380203/380291 Fax: +39-+39-0382 24714 Durata: anni 5 Neuropsichiatria Infantile Director: prof Giovanni Lanzi Location: Dip. di Scienze Neurologiche - Via Palestro, 3 Tel: +39-+39-0382 380236/380203 Fax: +39-+39-0382 24714 Durata: anni 5 Oftalmologia Director: prof. Fernando Trimarchi Location: Clinica Oculistica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526213 Durata: anni 4 Oncologia Director: prof. Location: - Sez. di Medicina Interna e Oncologia Medica –Policlinico S. Matto - P.le Golgi, 2 Tel: +39-+39-0382 526284/502580 Durata: anni 4 Ortopedia e Traumatologia Director: prof. Location: Sez. Ortopedica e Traumatologica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526375/502853 Durata: anni 5 Otorinolaringoiatria Director: prof. Eugenio Mira Location: Clinica Otorinolaringoiatrica - Policlinico San Matteo - Piazzale Golgi , 2 Tel: +39-+39-0382 526218 Durata: anni 4 Patologia clinica Director: prof. Vanio Vannini Location:Dip. di Medicina Sperimentale – Sez. di Patologia Generale - Piazza Botta, 10 Tel: +39-+39-0382 506333 Durata: anni 5 Pediatria Director: prof. Giorgio Rondini Location: Dipartimento di Scienze Pediatriche- Policlinico San. Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526269 Durata: anni 5 Psichiatria Director: prof. Fausto Petrella Location: Cascina Cravino - Via Bassi, 21 Tel: +39-+39-0382 987250 Durata: anni 4 Radiodiagnostica Director: prof. Location: Sezione di Radiologia - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 525725 Durata: anni 4 Radioterapia Director: prof. Vanio Vannini Location: Sezione di Radiologia - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 503736/525725 Durata: anni 4 Reumatologia Director: prof. Carlo Maurizio Montecucco Location: Reparti speciali – IV piano - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 501878 Durata: anni 4 Scienza dell’alimentazione Director: prof. Carla Roggi Location: Dip. di Scienze Sanitarie Applicate e Psicocomportamentali - Via Bassi, 21 Tel: +39-+39-0382 987543 Durata: anni 4 Tossicologia Medica Director: prof. Luigi Manzo Location: Dip. di Medicina Interna e Ter. Medica – Sez. Medicina Interna e Tossicologia clinica – Piazza Botta, 10 Tel: +39-+39-0382 26261 Durata: anni 4 Urologia Director: prof. Stefano Tinozzi Location: Clinica Chirurgica - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 502519 - 502504 Durata: anni 5 Idrologia Medica Director: prof. Francantonio Bertè Location: Dip. di Medicina Interna e Terapia Medica – Sez. di Farmacologia e Tossicologia cellulare e Molecolare - Piazza Botta, 10 Tel: +39-+39-0382 506343 Durata: anni 4 Ortognatodonzia Director: prof. Giuseppe Sfondrini Location: Dip. di Discipline Odontostomatologiche - Policlinico San Matteo - Piazzale Golgi, 2 Tel: +39-+39-0382 526221 Durata: anni 3 RESEARCH DOCTORATES CHIRURGIA SPERIMENTALE E MICROCHIRURGIA Location: Dipartimento di Chirurgia Durata 4 anni PATOLOGIA E GENETICA Location: Dipartimento di Patologia Umana ed Ereditaria Durata 3 anni SANITÀ PUBBLICA, SCIENZE SANITARIE E FORMATIVE Location: Dipartimento di Scienze Sanitarie Applicate e Psicocomportamentali Durata 4 anni FARMACOLOGIA E FARMACOEPIDEMIOLOGIA Location: Dipartimento di Medicina Interna e Terapia Medica Durata 4 anni MEDICINA INTERNA E TERAPIA MEDICA Location: Dipartimento di Medicina Interna e Terapia Medica Durata 4 anni SCIENZE NEUROLOGICHE E NEUROPSICHICHE Location: Dipartimento di Scienze Neurologiche Durata 4 anni MASTER Master Master Master Master Master Master di di di di di di I livello in "Hygiene, Sicurezza e qualità degli alimenti" I livello in “Tutoring infermieristico e ostetrico” I livello in “Infermieristica in Area Critica” I livello in “Infermieristica Geriatria” II livello in "Medicina d'Urgenza e Pronto Soccorso” II livello in “Agopuntura Medica e Fitofarmacologia Cinese”