Andrea Aliverti, Curriculum Vitae – Page 1 ANDREA
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Andrea Aliverti, Curriculum Vitae – Page 1 ANDREA
Andrea Aliverti, Curriculum Vitae – Page 1 ANDREA ALIVERTI CURRICULUM VITAE Born in Como, Italy on 14 March 1966. CURRENT POSITION Associate Professor of Biomedical Engineering, Dipartimento di Bioingegneria, Politecnico di Milano, Italy PROFESSIONAL EDUCATION 1992. Master Degree (Laurea) in Electronic Engineering. Politecnico di Milano 1997. PhD (Dottorato di Ricerca) in Biomedical Engineering. Politecnico di Milano. Thesis title: “Innovative methods and techniques to study respiratory mechanics”. 1998. Associate Professor (Researcher) at the Dipartimento di Bioingegneria, Politecnico di Milano, Italy RESEARCH ACTIVITIES Research field: bioengineering of the respiratory system. Current areas of interest include: a) Development of innovative methods for optoelectronic analysis of thoraco-abdominal kinematics and volumes during respiration. b) Development of double body Plethysmography for measuring blood shifts from and to the trunk; c) Modelling of respiratory mechanics: functional models of the actions of respiratory muscles; rib cage mechanics; measurement of the viscoelastic properties of the respiratory system; cardiopulmonary interactions during exercise. d) Creating a deeper understanding of the physiology and pathophysiology of the respiratory system in exercise; the effects of flow limitation on chest wall mechanics during exercise; the effects of mechanical ventilation and anesthesia on thoraco-abdominal motion; electrical stimulation of respiratory muscles; respiratory kinematics in pulmonary and neuromuscular disease. e) Development of software and hardware systems particularly with regard to measurement problems (volume, flow, pressure, gas concentration and motion) of the respiratory system; development of new methods of respiratory mechanics analysis based on the forced oscillation technique; development of new methods for the measurements of oxygen consumption on a breath-by-breath basis. f) Analysis of mono- and bi-dimensional physiologic signals, in particular, the correlation between motion of the external thoraco-abdominal surface area with the internal motion of the lung and diaphragm (measured by ultrasound); g) Development of new methods for the functional and morphometric analysis of healthy and emphysematous lung by Computed Tomography (CT) h) Three-dimensional echography and computer-aided surgery. Other research fields include development and validation of innovative technologies for quantitative analysis of human motion with diverse applications in biology and medicine: respiration, rehabilitation, recovery of motor function, morphological analysis of the body surface, computer aided surgery. SCIENTIFIC SOCIETIES Member of the European Respiratory Society (ERS). ERS officer (secretary of the group ‘Respiratory Structure and Function’ from 2009 to 2011; chair of the group 4.01 “Clinical Physiology and Exercise” from 2011 to 2014). Chairman of the ERS Research Seminar: “The Limits to Exercise in COPD: New Insights from New Methods” (Como, Italy, September 2007) COLLABORATIVE RESEARCH Visiting scientist at the following Universities: McGill University, Canada, University of Pennsyvania, Philadelphia, USA, Washington University in St Louis, USA, University of Zurich, Switzerland, University of Liverpool, UK, University of Athens, Greece, University of Uppsala, Sweden; Universidade Federal de Pernambuco, Recife, Brazil. TEACHING AND OTHER DIDACTIC ACTIVITIES Andrea Aliverti, Curriculum Vitae – Page 2 • Professor of “Technologies for Sensors and Clinical Instrumentation” of the Master Program in Biomedical Engineering of the Politecnico di Milano University. • Professor of “Bioengineering of Autonomic Control and Respiratory Systems” of the Master Program in Biomedical Engineering of the Politecnico di Milano University. • Professor of “Biological measurements” of the PhD Program in Biomedical Engineering of the Politecnico di Milano University. Thesis supervision Since 1993, supervisor or co-supervisor of 75 Master Theses in Biomedical Engineering or Electronic Engineering at the Politecnico di Milano (Faculty of Engineering). HONOURS AND AWARDS 2004 – Winner of the 2nd prize (20,000 €) of the “ERS (European Respiratory Society) - COPD Award 2004” 1998 – Winner of the Prize Paolo Durst, Microtec, from the Interdisciplinary Centre of Bioengineering, Università di Padova, for the best Italian PhD thesis in Biomedical Engineering . 1998 – APICE (Anaesthesia, Pain, Intensive Care and Emergency Medicine), Trieste, Italy – Best contribution in the poster session “Intensive Care” Editorial activities Member of the Editorial Board of the following journals: - Advances in Therapy - ISRN Pulmonology LIST of PUBLICATIONS FULL PEER-REVIEWED PAPERS 1. Hostettler S, Illi SK, Mohler E, Aliverti A, Spengler CM. Chest wall volume changes during inspiratory loaded breathing. Respir Physiol Neurobiol; 175(1):130-9, 2011. 2. Aliverti A, Uva B, Laviola M, Bovio D, Lo Mauro A, Tarperi C, Colombo E, Loomas B, Pedotti A, Similowski T, Macklem PT. Concomitant ventilatory and circulatory functions of the diaphragm and abdominal muscles. J Appl Physiol; 109(5):1432-40, 2010 3. Wilkens H, Weingard B, Lo Mauro A, Schena E, Pedotti A, Sybrecht GW, Aliverti A. Breathing pattern and chest wall volumes during exercise in patients with cystic fibrosis, pulmonary fibrosis and COPD before and after lung transplantation. Thorax; 65(9):808-14, 2010. 4. Baldi S, Dellacà R, Govoni L, Torchio R, Aliverti A, Pompilio P, Corda L, Tantucci C, Gulotta C, Brusasco V, Pellegrino R. Airway distensibility and volume recruitment with lung inflation in COPD. J Appl Physiol; 109(4):1019-26, 2010 5. Vogiatzis I, Athanasopoulos D, Habazettl H, Aliverti A, Louvaris Z, Cherouveim E, Wagner H, Roussos C, Wagner PD, Zakynthinos S. Intercostal muscle blood flow limitation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med; 182(9):1105-13, 2010 6. Romei M, Mauro AL, D'Angelo MG, Turconi AC, Bresolin N, Pedotti A, Aliverti A. Effects of gender and posture on thoraco-abdominal kinematics during quiet breathing in healthy adults. Respir Physiol Neurobiol;172(3):184-91, 2010 7. Calverley P, Miserocchi G, Puente Maestu L, Aliverti A, De Backer W, Andreas S, Humbert M. The changing face of respiratory physiology: 20 years of progress within the ERS: Clinical Physiology and Integrative Biology Assembly contribution to the celebration of 20 years of the ERS. Eur Respir J; 35(5):945-8, 2010 8. Kayser B, Aliverti A, Pellegrino R, Dellaca R, Quaranta M, Pompilio P, Miserocchi G, Cogo A. Comparison of a visual analogue scale and Lake Louise symptom scores for acute mountain sickness. High Alt Med Biol; 11(1):69-72, 2010 9. Khirani S, Polese G, Aliverti A, Appendini L, Nucci G, Pedotti A, Colledan M, Lucianetti A, Baconnier P, Rossi A. On-line monitoring of lung mechanics during spontaneous breathing: a physiological study. Respir Med; 104(3):463-71, 2010 Andrea Aliverti, Curriculum Vitae – Page 3 10. Pellegrino R, Pompilio P, Quaranta M, Aliverti A, Kayser B, Miserocchi G, Fasano V, Cogo A, Milanese M, Cornara G, Brusasco V, Dellacà R. Airway responses to methacholine and exercise at high altitude in healthy lowlanders. J Appl Physiol; 108(2):256-65, 2010 11. Lo Mauro A, D'Angelo MG, Romei M, Motta F, Colombo D, Comi GP, Pedotti A, Marchi E, Turconi AC, Bresolin N, Aliverti A. Abdominal volume contribution to tidal volume as an early indicator of respiratory impairment in Duchenne muscular dystrophy. Eur Respir J; 35(5):1118-25, 2010 12. Sarro KJ, Silvatti AP, Aliverti A, Barros RM. Proposition and evaluation of a novel method based on videogrammetry to measure three-dimensional rib motion during breathing. J Appl Biomech.;25(3):24752, 2009 13. Aliverti A, Kayser B, Cautero M, Dellacà RL, di Prampero PE, Capelli C. Pulmonary V’O2 kinetics at the onset of exercise is faster when actual changes in alveolar O2 stores are considered. Respir Physiol Neurobiol.;169(1):78-82, 2009 14. Salito C, Aliverti A, Gierada DS, Deslée G, Pierce RA, Macklem PT, Woods JC. Quantification of trapped gas with CT and 3 He MR imaging in a porcine model of isolated airway obstruction. Radiology; 253(2):380-9, 2009 15. Aliverti A, Bovio D, Fullin I, Dellacà RL, Lo Mauro A, Pedotti A, Macklem PT. The abdominal circulatory pump. PLoS One. ;4(5):e5550, 2009 16. Quaranta M, Salito C, Magalotti E, Monaco P, Forlani C, Pedotti A, Aliverti A. Non-invasive threedimensional imaging of human diaphragm in-vivo. Conf Proc IEEE Eng Med Biol Soc.; 5278-81, 2008 17. Aliverti A, Quaranta M, Chakrabarti B, Albuquerque AL, Calverley PM. Paradoxical movement of the lower ribcage at rest and during exercise in COPD patients. Eur Respir J;33(1):49-60, 2009 18. Aliverti A. Lung and chest wall mechanics during exercise: effects of expiratory flow limitation. Respir Physiol Neurobiol;163(1-3):90-9, 2008 19. Aliverti A, Macklem PT. Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation. J Appl Physiol; 105(2):763, 2008 20. Aliverti A, Macklem PT. The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles. J Appl Physiol; 105(2):749-51; discussion 755-7, 2008 21. Wüst RC, Aliverti A, Capelli C, Kayser B. Breath-by-breath changes of lung oxygen stores at rest and during exercise in humans. Respir Physiol Neurobiol; 164(3):291-9, 2008 22. Aliverti A. Chest Wall Mechanics in COPD. Curr Respir Med Rev, 4, 4: 240-249(10), 2008 23. Cossette I, Monaco, P, Aliverti A, Macklem PT. Chest Wall Dynamics and Muscle Recruitment during Professional Flute Playing. Respir Physiol Neurobiol, 160:187-195, 2008 24. Chiumello D, Carlesso E, Aliverti A, Dellaca RL, Pedotti A, Pelosi PP,Gattinoni L. Effects of volume shift on the pressure-volume curve of the respiratory system in ALI/ARDS patients. Minerva Anestesiol. 2007 Mar;73(3):109-18. (*) 25. Aliverti A, Kayser B, Macklem PT. A human model of the pathophysiology of Chronic Obstructive Pulmonary Disease. Respirology 2007; 12: 478–485 (*) 26. Dellaca RL, Duffy N, Pompilio PP, Aliverti A, Koulouris NG, Pedotti A, Calverley PM. Expiratory flow limitation detected by forced oscillation and negative expiratory pressure. Eur Respir J. 2007 Feb;29(2):363-74. 27. Georgiadou O, Vogiatzis I, Stratakos G, Koutsoukou A, Golemati S, Aliverti A, Roussos C, Zakynthinos S. Effects of rehabilitation on chest wall volume regulation during exercise in COPD patients. Eur Respir J. 2007 Feb;29(2):284-91. 28. Vogiatzis I, Zakynthinos S, Georgiadou O, Golemati S, Pedotti A, Macklem PT, Roussos C, Aliverti A. Oxygen kinetics and debt during recovery from expiratory flow-limited exercise in healthy humans. Eur J Appl Physiol. 2007 Feb;99(3):265-74. 29. Dellaca RL, Rotger M, Aliverti A, Navajas D, Pedotti A, Farre' R. Non-invasive detection of expiratory flow limitation in COPD patients during nasal CPAP. Eur Respir J. 2006 May;27(5):983-91 30. Aliverti A., P.T. Macklem. A human model of chronic obstructive pulmonary disease (Ein experimentelles Modell zum Studium der COPD beim gesunden Menschen) Intensivmed, 43:296–300, 2006. 31. Aliverti A, Carlesso E, Dellacà RL, Pelosi P, Chiumello D, Pedotti A and Gattinoni L. Chest wall mechanics during pressure support ventilation. Crit Care. 2006;10(2):R54 32. Patruno F, Aliverti A, Dellacà RL, Pedotti A and Burns D. Redundant system of passive markers for ultrasound scanhead tracking. IEEE Trans Biomed Eng 52: 88-96, 2005. Andrea Aliverti, Curriculum Vitae – Page 4 33. Vogiatzis I, Aliverti A, Golemati S, Georgiadou O, Lo Mauro A, Kosmas E, Kastanakis E, Roussos C. Respiratory kinematics by optoelectronic plethysmography during exercise in men and women. Eur J Appl Physiol, 93: 581-587, 2005. 34. Vogiatzis I, Georgiadou O, Golemati S, Aliverti A Kosmas E, Kastanakis E, Geladas N Koutsoukou A, Nanas S, Zakynthinos S, Roussos C, and. Patterns of dynamic hyperinflation during exercise and recovery in patients with severe chronic obstructive pulmonary disease. Thorax 60: 723-729, 2005. 35. Aliverti A, Rodger K, Dellaca RL, Stevenson N, Lo Mauro A, Pedotti A, and Calverley PMA. Effect of salbutamol on lung function and chest wall volumes at rest and during exercise in COPD. Thorax 60: 916924, 2005. (*) 36. Aliverti A, Dellaca RL, Lotti P, Bertini S, Duranti R, Scano G, Heyman J, Lo Mauro A, Pedotti A, Macklem PT. Influence of expiratory flow-limitation during exercise on systemic oxygen delivery in humans. Eur J Appl Physiol, 95: 229-242, 2005. 37. Dellacà RL, Santus P, Aliverti A, Stevenson N, Centanni S, Macklem PT, Pedotti A, Calverley PMA. Detection of expiratory flow limitation in COPD using the forced oscillation technique. Eur Respir J, 23: 232-240, 2004 (*) 38. Aliverti A, Kayser B, Macklem PT. Breath-by-Breath Assessment of Alveolar Gas Stores and Exchange. J Appl Physiol. J Appl Physiol, 96(4):1464-9, 2004 39. Aliverti A, Stevenson N, Dellacà RL, Lo Mauro A, Pedotti A, Calverley PMA. Regional Chest Wall Volumes during exercise in Chronic Obstructive Pulmonary Disease. Thorax, 59 210-216, 2004 40. Pellegrino R., Dellacà R., Macklem P.T., Aliverti A., Bertini S., Lotti P., Agostoni P.G., Locatelli A., and Brusasco V. Effects of rapid saline infusion on lung mechanics and airway responsiveness in humans. J Appl Physiol, 95:728–734, 2003 41. Aliverti A, Pedotti A. Opto-electronic plethysmography. Monaldi Arch Chest Dis;59(1):12-6, 2003 42. Dellacà R.L., Aliverti A., Lutchen K.L., Pedotti A. Spatial distribution of human respiratory system transfer impedance. Ann Biomed Eng, 31:121-131, 2003 43. Aliverti A, Ghidoli G, Dellaca R.L., Pedotti A., Macklem P.T. Chest wall kinematic determinants of diaphragm fibre length measured by opto-electronic plethysmography and ultrasonography. J Appl Physiol 94(2): 621-630, 2003 44. Kandare F, Exner G, Jeraj J, Aliverti A, Dellacà R, Stanic U, Pedotti A, Jaeger R. Breathing induced by abdominal muscle stimulation in individuals without spontaneous ventilation. Neuromodulation, 5(3): 180-185, 2002 45. Aliverti A, Iandelli I, Duranti R, Cala S, Kayser B, Kelly S, Misuri G, Pedotti A, Scano G, Sliwinski P, Yan S, Macklem PT. Respiratory muscle dynamics and control during exercise with externally imposed expiratory flow-limitation. J Appl Physiol, 92(5): 1953-1963, 2002 46. Iandelli I, Aliverti A, Kayser B, Dellacà R, Cala S, Duranti R, Kelly S, Scano G, Sliwinski P, Yan S, Macklem PT, Pedotti A. Determinants of exercise performance in normal men with externally imposed expiratory flow-limitation. J Appl Physiol, 92(5): 1943-1952, 2002 47. Aliverti A, R. Dellacà, Pedotti A. Opto-electronic plethysmography: A new technique in respiratory medicine [Pletismografia optoelettronica: Un nuovo strumento in medicina respiratoria]. Rec Prog Med, 92(11): 644-647 , 2001 48. Aliverti A, R. Dellacà, P. Pelosi, D. Chiumello, L. Gattinoni and A. Pedotti. Compartmental analysis of breathing in the supine and prone positions by Opto-Electronic Plethysmography. Ann Biomed Eng 29:6070, 2001 49. Aliverti A., P.T. Macklem. How and why exercise is impaired in COPD. Respiration 68:229-239, 2001 50. Aliverti A., R. Dellacà and A. Pedotti. Transfer impedance of the respiratory system by forced oscillation technique by optoelectronic plethysmography. Ann Biomed Eng 29:71-82, 2001 51. Dellacà R., A. Aliverti A., P. Pelosi, E. Carlesso, D. Chiumello, A. Pedotti and L. Gattinoni. Estimation of end-expiratory lung volume variations by opto-electronic plethysmography (OEP). Crit Care Med. 29(9):1807-1811, 2001 52. Aliverti A, R. Dellacà , P. Pelosi, D. Chiumello, A. Pedotti , L. Gattinoni. Opto-electronic plethysmography in intensive care patients. Am. J. Respir. Crit. Care Med., 161: 1546-1552, 2000 53. Pelosi P, Aliverti A, Dellacà R. Chest wall mechanics in normal subjects and in critically ill patients. [Die Mechanik der Brustwand bei normalen Personen und bei Patienten in kritischem Zustand]. Intensivmed (Intensivmedizin und Notfallmedizin) 37: 341-351, 2000 54. Rigotti C, Ferrigno G, Aliverti A and Pedotti A. Surface scanning: an application to mammary surgery. Journal of Biomedical Optics, 3(2): 161-170, 1998 Lissoni A, Aliverti A, Tzeng AC and Bach JR. Andrea Aliverti, Curriculum Vitae – Page 5 Kinematic analysis of patients with spinal muscular atrophy during spontaneous breathing and mechanical ventilation. Am J Phys Med Rehabil, 77:3 188-92, 1998 55. Aliverti A, Cala SJ, Duranti R, Ferrigno G, Kenyon CM, Pedotti A, Scano G, Sliwinski P, Macklem PT and Yan S. Human Respiratory Muscle Actions and Control during Exercise. J Appl Physiol 83(4): 12561269, 1997 56. Kenyon CM, Cala SJ, Yan S, Aliverti A, Scano G, Duranti R, Pedotti A and Macklem PT. Rib Cage Mechanics during Quiet Breathing and Exercise in Humans. J Appl Physiol 83(4): 1242-1255, 1997 57. Cattaneo T, Lissoni A, Molteni F and Aliverti A. Positive pressure ventilation in patients with neuromuscular disease: Assisted or controlled? Europa Medicophysica 31: 141-146, 1995.Aliverti A, Molteni F, Carnevali P, Pedotti A, Bach JR and Lissoni A. Thoraco-abdominal kinematics in Duchenne muscular dystrophy. Eur J Phys Med Rehab, 7: 8-13, 1997 58. Lissoni A and Aliverti A. Kinematic analysis of spinal muscular atrophy patients during spontaneous breathing and mechanical ventilation. Europa Medicophysica 33: 165-170, 1997. 59. Lissoni A, Aliverti A, Navalesi P and Molteni F. The study of breathing kinematics in spinal muscle atrophy patients. Acta Cardiomiologica 8: 17-26, 1996. 60. Carnevali P, Ferrigno G, Aliverti A and Pedotti A. A new method for 3D optical analysis of chest wall motion. Technology and Health Care 4: 43-65, 1996 61. Lissoni A, Aliverti A, Molteni F and Bach JR. Spinal Muscular Atrophy: Kinematic Breathing Analysis. Am J Phys Med Rehabil 75: 332-339, 1996 62. Cala SJ, Kenyon C, Ferrigno G, Carnevali P, Aliverti A, Pedotti A, Macklem PT and Rochester DF. Chest wall and lung volume estimation by optical reflectance motion analysis. J Appl Physiol 81(6): 2680-2689, 1996 63. Ferrigno G, Carnevali P, Aliverti A, Molteni F, Beulke G and Pedotti A. Three-dimensional Optical Analysis of Chest Wall Motion. J Appl Physiol 77(3): 1224-1231, 1994 (*) Editorialized BOOKS 64. Lucangelo U, Pelosi P, Zin WA, Aliverti A (Eds.) Respiratory System and Artificial Ventilation. Springer Verlag, 2007, ISBN: 978-88-470-0764-2 65. Aliverti A, Brusasco V, Macklem PT, Pedotti A (eds.). Mechanics of breathing: pathophysiology, diagnosis and treatment. Springer Verlag, 2002 66. Pedotti A, Aliverti A, Andreoni G, Ferrigno G. Tecnologie biomediche: esempi di applicazione ed esercizi. Libreria Clup, 2001 67. Santambrogio GC, Aliverti A, Andreoni G, Gabardi C. Analisi Motoria: Esercizi Svolti e Commentati. Soc. Esculapio Editrice Bologna, 1996 BOOK CHAPTERS 68. Aliverti A. Monitoring of Respiratory Mechanics in the ICU: Models, Techniques and Measurement Methods. In: Respiratory System and Artificial Ventilation .Lucangelo U, Pelosi P, Zin WA, Aliverti A (Eds.), Springer Verlag, 2007, pp. 73-97 69. Aliverti A., “Misure di meccanica respiratoria: metodi e tecniche”, in: Medicina Perioperatoria, Terapia Intensiva, Emergenza, a cura di Gullo A., Springer-Verlag Italia - Milano (Publ.), pp. 323-342, 2002 70. Aliverti A. Optoelectronic plethysmography in the Intensive Care Unit. In: Mechanics of breathing: pathophysiology, diagnosis and treatment. Aliverti A, Brusasco V, Macklem PT, Pedotti A (eds.) Springer Verlag, 314-326, 2002 71. Aliverti A, Pedotti A. Optoelectronic plethysmography. In: Mechanics of breathing: pathophysiology, diagnosis and treatment. Aliverti A, Brusasco V, Macklem PT, Pedotti A (eds.) Springer Verlag, 47-59, 2002 72. Dellacà R., Aliverti A. Meccanica oscillatoria del sistema respiratorio. In: Bioingegneria del sistema respiratorio, Avanzolini G., Barbini P., Costantino M.L., Pedotti A., Rossi A. (eds.). Pàtron Editore, Bologna, pp. 191-203, 2001 73. Aliverti A., Dellacà R. Meccanica della parete toraco-addominale. In: Bioingegneria del sistema respiratorio, In Avanzolini G., Barbini P., Costantino M.L., Pedotti A., Rossi A. (eds.). Pàtron Editore, Bologna, pp. 49-62, 2001 Andrea Aliverti, Curriculum Vitae – Page 6 74. Pedotti A, Aliverti A. Metodi di analisi del sistema respiratorio. In: Bioingegneria del sistema respiratorio, Avanzolini G., Barbini P., Costantino M.L., Pedotti A., Rossi A. (eds.). Pàtron Editore, Bologna, pp. 2943, 2001 75. Pelosi P, Aliverti A and Dellacà R. Chest wall mechanics: methods of measurement and physiopathologic insights. In Yearbook of Intensive Care and Emergency Medicine, JL Vincent (ed), Springer-Verlag, Berlin, pp. 361-376, 1998. 76. Aliverti A, Pedotti A, Ferrigno G and Macklem PT. Respiratory kinematics by optoelectronic analysis of chest wall motion and ultrasonic imaging of the diaphragm In Physiology and Function from Multidimensional Images, ed. by E.A.Hoffmann, pub. by SPIE The international Society for Optical Engineering, vol. 3337, 52-62, 1998 77. Aliverti A, Ferrigno G. RLC model of the visco-elastic properties of the chest wall. In Physiology and Function from Multidimensional Images, ed. by E.A.Hoffmann, pub. by SPIE The international Society for Optical Engineering, vol. 2709, 21-31, 1996 78. Aliverti A, Ferrigno G, Rotelli F, Santambrogio GC. Back Surface analysis by Laser Beam Scanning and Stereophotogrammetry. In Three dimensional Analysis of Spinal Deformities. M. D'Amico et al. (Eds.). IOS Press, 51-56, 1995 79. Aliverti A, Ferrigno G and Pedotti A. Surface analysis by laser beam scanning and stereophotogrammetry. In Videometrics II, ed. by S.F.El-Hakim, pub. by SPIE The International Society for Optical Engineering, vol. 2067, 209-219, 1993 PATENTS Inventor of 9 patents, including: • An abdominal circulatory pump device • A system for airway bypass site selection and treatment planning • A system for respiratory support and detection of alveolar derecruitment • A dual body plethysmography for measuring blood flow between the trunk and the body periphery. • An apparatus for navigation and fusion of echographic images • A system and methods for the automatic detection of expiratory flow limitation. • A measurement system of respiratory kinematics in humans • A measurement system of respiratory mechanics in humans • A measurement system of diaphragm kinematics in humans