PHOTO FET Concertation meeting OLAE_2010 - CNR

Integrated Photonic Field-Effect technology for
bio-sensing functional components (PHOTO-FET)
www.photofetproject.eu
Michele Muccini, coordinator
CNR, Istituto per lo Studio dei Materiali Nanostrutturati
(ISMN), Bologna, Italy
[email protected]
OLAE
Meeting
Brussels
2010
STREP Project
Commencement date: 01.01.2010
Duration: 36 months
Content
◊ PHOTO-FET Consortium
◊ Photonic FET platform for Point of Care diagnostics
◊ PHOTO-FET objective
◊ Major technological challenges
◊ Exploitation potential
OLAE
Meeting
Brussels
2010
◊ Benefit from cooperation
Who are we?
Partner
OLAE
Meeting
Brussels
2010
Organisation
Country Business activity area
CO
1
CNR- Istituto per
lo Studio dei
Materiali
Nanostrutturati,
Bologna
(CNR-ISMN)
Imperial College
London (ICL)
P
2
P
3
Politecnico
Milano(IT)
di
IT
P
4
The Swiss Center
for Electronics and
Microtechnology,
Inc., (CH)
CH
P
5
Molecular Vision
ltd
UK
P
6
Saes Getters
S.p.A.
IT
RTD role in project
IT
Gov. Res. Org.
Research on advanced
optoelectronic and photonic
devices
Coordination, LE-FET Technology, Laser Scanning
Confocal microscopy and spectroscopy,
optoelectronic characterisation of materials and
heterojunctions, imaging of organic thin films and
interfaces.
UK
University
Res. Cent.
R&D in Experimental Solid
State Physics
University
Res. Cent,
R&D in Ultrafast photonics
Private R&D centre
specializing in
microtechnology,
nanotechnology,
microelectronics, systems
engineering.
SME
Lab-on-a-chip technology,
Low-cost diagnostic devices
LS-FET Technology, integration of passive optical
components onto microfluidic chips.
Industrial Res. Lab, Res &
Innovation Dept. Material
science
Photonic characterisation of materials and devices.
Ultrafast spectroscopy.
Microfluidic technology, integration of Photonic
FET devices onto microfluidic chips, modelling and
design of photonic microfluidic chips.
Specifications for cardiovascular monitoring
applications, implementation of assays into
microfluidic structures, circuit design, technology
assessment.
Thin Film encapsulation and packaging
technologies, liquid scavengers development, getters
integration in PHOTO-FET devices, packaging of
photonic bio-sensing components, technology
assessment, exploitation.
Point-of-Care (PoC) diagnostics: search
for disposable, fast, cheap, quantitative
and precise devices
photodetector
glass
glass
light
light
Schematic of a Polymer Detection System
developed at Molecular Vision
OLED
A microfluidic chip for testing of renal health:
incorporating a microfluidic chip, organic LEDs
and photodetectors
Courtesy of Molecular Vision Ltd
OLAE
Meeting
Brussels
2010
Major Pro:
avoids bulky optical light-sources and detectors
Building a Photonic field-effect platform
OLET concept
2D switching device enabling nanoscale integrated light-sources
~ 100 µm
Charge
accumulation
region
~ 5 nm
M. Muccini, “A bright future for field-effect transitors” , Nature Mat., 2006, 5, 605
Capelli, Toffanin, Muccini et al., Nature Materials, 2010, 9, 496
OLED concept
Vertical working geometry enabling large area light emission
Catode
Hole transpot layer
Emitting layer
El. transport layer
Anode
OLAE
Meeting
Brussels
2010
emission
~ 100 nm
PHOTO-FET approach to PoC diagnostics
Light-Emitting and Light-Sensing FET
integration on chip
OLAE
Meeting
Brussels
2010
PHOTO-FET Objective
To develop a miniaturized cheap and disposable photonic device
for bio sensing with unprecedented sensitivity and superior reliability
at a markedly reduced cost.
OLAE
Meeting
Brussels
2010
PHOTO-FET Approach
Principle benefits
◊ Pre-fabrication on the substrate:
optimal registration between photonic devices and fluidic chip
◊ Simplified photonic device fabrication processing:
potentially single layer devices can be used
◊ Improved optical coupling and guiding:
significant performance gains can be expected
◊ Straightforward integration of auxiliary transistors:
improved electrical driving and signal amplification at the
point-of-generation
OLAE
Meeting
Brussels
2010
Major technological challanges
◊ To realize microfluidic devices with integrated passive optical
component for multiple cardiac markers
◊ To realize high performance OLET devices compatible
for integration onto microfluidic chips.
Nature Materials, 2010, 9, 496
◊ To realize high performance LS-FET devices compatible
for integration onto microfluidic chips.
OLAE
Meeting
Brussels
2010
◊ To monolithically integrate and package photonic bio-sensing
components based on OLETs, LS-FETs and optical microfluidic
chips.
Exploitation potential
◊ Patterned liquid getter technology and innovative packaging solutions
◊ Methods and architectures for monolithic integration of components
on chips
◊ Commericiaize troponin/myoglobin/pro-BNP PoC diagnostic devices
◊ Light-Emitting Transistor technology for planar micron-size light
sources and display technology
OLAE
Meeting
Brussels
2010
◊ Light-sensing FET technology
Benefit from cooperation
Principle synergies aimed at decreasing development time
and broaden exploitation opportunities
◊ advanced materials development
(dielectrics, organic semiconductors, emitters)
◊ advanced manufacturing of components and integrated chips
◊ use of PHOTO-FET technology platform for complementary
applications (security, display technology, metrology, etc..)
OLAE
Meeting
Brussels
2010