sebastiano calandra buonaura - Laurea in Ostetricia

SEBASTIANO CALANDRA BUONAURA
Ruolo
Professore ORDINARIO
Ufficio
Dipartimento di Scienze Biomediche, Università di Modena e Reggio
Emilia
Telefono
059-2055-423
E-mail
[email protected]
Ricevimento
Previo appuntamento via mail
Corso di Laurea
In OSTETRICIA
Corso Integrato
Scienze Biomediche 2
Insegnamento
Patologia Generale 1
Breve Curriculum Vitae
Prof. Sebastiano Calandra Buonaura, Dipartimento di Scienze Biomediche, Università di
Modena e Reggio Emilia
Breve Curriculum Vitae
Laureato in Medicina e Chirurgia, Università di Modena 1966,
Medico Interno, Dipartimento di Medicina Interna 1967/68,
Research Fellow, Liver Unit, Department of Medicine, Royal Free Hospital, University of
London, 1969/70,
Assistente Universitario alla Cattedra di Patologia Generale, Università di Modena, 1971/1982
Specializzato in Medicina di Laboratorio, Università di Ferrara, 1974
Research Fellow, Department of Genetics and Medicine, Southwestern Medical School,
Università del Texas, Dallas 1976-77.
Visiting Scientist, Department of Cell Biology Baylor College of Medicine, Houston, TX 1984
Professore Associato di Patologia Generale, Università di Modena, 1983-1986
Professore Ordinario di Patologia Generale, Università di Modena e Reggio Emilia, Facoltà di
Medicina e Chirurgia, dal 1987 ad oggi.
Presidente del CdL in Medicina 1993/1998.
Direttore del Laboratorio di sequenziamento del genoma (LABGEN), Dipartimento di Scienze
Biomediche, Università di Modena & Reggio Emilia.
Direttore del Dipartimento di Scienze Biomediche, Università di Modena e Reggio Emilia, dal
aa.2006.
Segretario del European Atherosclerosis Society (EAS) dal 2000 al 2005.
Principali Linee di Ricerca:
1) Fisiopatologia e biochimica delle lipoproteine plasmatiche nell’uomo ed in modelli animali 2)
Genetica e Patologia Molecolare dei disordini ereditari del metabolismo delle lipoproteine e del
colesterolo
E’ autore di oltre 135 pubblicazioni, tutte su riviste internazionali indicizzate (Annals of
Neurology, Atherosclerosis, Arteriosclerosis Thrombosis and Vascular Biology, American
Journal of Human Genetics, Biochimica et Biophysica Acta, Biochemical and Biophysical
Research Communications, Circulation, Clinical Genetics, Clinica Chica Acta, Current Opinion
in Lipidology, Electrophoresis, Gastroenterology, Gene, Human Genetics, Human Gene
Therapy, Journal of Biological Chemistry, Journal of Hepatology, Journal of Lipid Research,
Journa of Internal Medicine, Journal of Pediatrics, Lancet, Molecular and Cell Biology,
Molecular Genetics and Metabolism, Movement Disorders, Science).
E’ Associate Editor della rivista “Atherosclerosis”.
Pubblicazioni più recenti
Rabacchi C, Wunsh A, Ghisellini M, Marino M, Pisciotta L, Bertolini S, Calandra S.
An apaprent incosistency in parent to offspring transmission of point mutations of LDLR gene
in familial hypercholesterolemia.
Clin Chim Acta 406: 75-80, 2009
Pisciotta L, fresa R, Bellocchio R, Pino E, Guido V, Cantafora A. Di Rocco M, Calandra S.
Bertolini S.
Cholesteryl ester strogage disease (CESD) due to novel mutations in the LIPA gene
Mol genet Metab 97: 143-148, 2009
Guardamagna O. Restagno G, Rolfto E, Pederiva C, Martini S, Abello F, Baracco V, Pisciotta L,
Pino E, Calandra S. Bertolini S.
The type of LDLR gene mutation predicts cardiovascular risk in children with familial
hypercholesterolemia. J Pediatr. 155: 199-204, 2009
Fancello T, Dardis A, Rosano C, Tarugi P, Tappino B, Zampieri S, Pinotti E. Corsolini F,
Fecarotta S, D’Amico A, Di Rocco M. Uziel G, Calandra S, Bembi B, Filocamo M.
Molecular analysis of NPC1 and NPC2 gene in 34 Niemann-Pick C Italian patients:
identification and structural modelling of novel mutations.
Neurogenetics 10: 229-239, 2009
Pisciotta L, Bocchi L, Candini C, Sallo R, Zanotti I, Fasano T, Chakrapani A, Bates T, Bonari R,
Cantafora A, Ball S, Watts G, Bernini F, Calandra S, Bertolini S.
Severe HDL deficiency due to novel defects of ABCA1 transporter
J Int Med 265: 359- 372, 2009
Calabresi L, Nilsson P, Pinotti E, Gomaraschi M, Favari E, Adorni MP, Bernini F, Sirtori CR,
Calandra S, Franceschini G, Tarugi P(2009), A novel homozygous mutation in CETP gene as a
cause of CETP deficiency in a caucasian kindred, Atherosclerosis ( in press, 2009)
I
Priore Oliva C, Carubbi F, Shaap FG, Bertolini S, Calandra S.
Hypertriglyceridemia and low plasma HDL in a patient with apolipoprotein A-V deficiency to a
novel mutation in the APOA-V gene.
J Int Med 263: 450-458, 2008
Pisciotta L, Fasano T, Calabresi L, Bellocchio A, Fresa R, Borrini C, Calandra S, Bertolini S. A
novel mutation of the apolipoprotein A-I gene in a family with familial combined
hyperlipidemia. Atherosclerosis;198:145-51, 2008
Charlton-Menys V, Pisciotta L, Durrington PN, Neary R, Short CD, Calabresi L, Calandra S,
Bertolini S,
Molecular characterization of two patients with severe LCAT deficiency. Nephrol Dial
Transplant. 22:2379-82, 2007
Di Leo E, Magnolo L, Lancellotti S, Crocè L, Visintin L, Tiribelli C, Bertolini S, Calandra S,
Tarugi P. Abnormal apolipoprotein B pre-mRNA splicing in patients with familial
hypobetalipoproteinaemia., J Med Genet;44:219-24, 2007
Pisciotta L, Fasano T, Bellocchio A, Bocchi L, Sallo R, Fresa R, Colangeli I, Cantafora A,
Calandra S,
Bertolini S. Effect of ezetimibe coadministered with statins in genotype-confirmed
heterozygous FH patients. Atherosclerosis. 194:e116-22, 2007
Calandra S, Priore Oliva C, Tarugi P, Bertolini S. APOA5 and triglyceride metabolism, lesson
from human APOA5 deficiency.Curr Opin Lipidol;17:122-7. 2005 Review
Pisciotta, L, Priore-Oliva, Cefalù AB, Noto D, Bellocchio A, Fresa R, Cantafora A, Patel D,
Averna M, Tarugi P, Calandra S, Bertolini S.
Additive effect of mutations in LDLR and PCSK9 genes on the phenotypic expression of Familial
Hypercholesterolemia
Atherosclerosis 186: 433-40, 2006
Pisciotta L, Oriore Oliva C, Pes GM, Di Scala L, Bellocchio A, Fresa R, Cantafora A, Arca,M,
Calandra S, Bertolini S.
Autosomal recessive hypercholestereolemia (ARH) and homozygous familial
Hypercholesterolemia (FH): a phenotypic comparison
Atherosclerosis 188: 398-405, 2006.
Sirinian M, Belleudi F, Campagna F, Ceridono M, Garofalo T, Quagliarini F, Verna R, Calandra
S., Bertolini S, Sorice M, Torrisi MR, Arca M.
Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL)
and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes
J Biol Chem 280: 38416-38423, 2005
Oliva CP, Pisciotta L., Li Volti, G., Sambataro MP, Cantafora A., Bellocchio A. Catapano, A.
Tarugi, P, Bertolini, S, Calandra S
Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia.
Arterioscler Thromb Vasc Biol. 25: 411-17, 2005
Calabresi. L., Pisciotta, L. et al., Calandra S., Bertolini S., Franceschini G
The molecular basis of lecithin: cholesterol acyltransferase deficiency syndromes: a
comprehensive study of molecular and biochemical findings in 13 unrelated Italian families
Arterioscler. Thromb. Vasc Biol. 25: 1972-78, 2005
Pisciotta L, Calabresi L, Lupatelli G, Siepi D, Mandarino MR, Moleri E, BellocchioA, Cantafora A,
Tarugi P, Calandra S, Bertolini S
Combined monogenic hypercholesterolemia and hypoalphalipoproteinemia caused by
mutation in LDL-R and LCAT genes
Atherosclerosis 182: 153-59, 2005
Fasano, T., Bocchi, L. Pisciotta L, Bertolini S, Calandra, S.
Denaturing high performance liquid chromatogrphy in the detection of ABCA1 gene mutations
in Familial HDL deficiency.
J Lipid Res 46: 817-22, 2005
Di Leo E, Lancellotti S. Pennachioni JY, Cefalù AB, Averna M, Pisciotta L. Bertolini S. Calandra
S, Gabelli C. Tarugi, P.
Mutations in MTP gene in abeta- and hypobeta-lipoproteinemia
Atherosclerosis 180: 311-18, 2005