5 - CIFA/ICEF

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5 - CIFA/ICEF
C
Centre IInternational
De Recherche et D’Etude
de
F
Facteurs de l’A
Ambiance
Association International
a but scientifique
(Monit. belge, 28 Aug. 1969)
January-April 2008
Supplemento a RICERCA AEROSPAZIALE www.aviolibri.it
-
Anno XXIV
n. 1
IN
X:
EX
DE
ND
Editorial by VINCENZO VALENZI (President of CIFA)
pag.
3
pag.
5
pag.
9
The Resolution of the 7th International Crimean Conference “COSMOS AND
BIOSPHERE”
(October 1 – 6, 207, Sudak, Ukraine)
Non invasive evaluation of pulse wave velocity (PWV) and endothelial
dysfunction (ED) by YURI GURFINKEL (Central clinical Hospital JSC “Russian
Railways and Space Research Institute RAS Moscow Russia)
Bakken's prehabilitation in the service of a budding chronoastrobiology
by F. HALBERG et l.
pag. 11
Resin ion exchange and fluctuating phenomena
by MARIAGRAZIA COSTA
pag. 17
Results and perspectives of studies of solar-biospheric connections in
The periods of solar eclipse by A. V. TROFIMOV (Scientific center of clinical
and experimental medicine SB RAMS - International SRI of cosmic anthropoecology
Novosibirsk, Russia, [email protected])
pag.
19
Is the biological test of Colony Sectoring (CSD) what Piccardi hoped to
support his intuitions? by PIERO FARAONE (V.President of CIFA)
pag. 21
The work of Davydov and scientific evidence of solitons in alive
systems by LARISSA BRIZHIK (Bogolyubov Institute for Theoretical Physics,
Metrologichna Str., 14-b, 03680 Kyiv)
pag. 29
Osservazioni sulle variazioni bioelettriche nell’uomo indotte da campi
elettromagnetici in camera amagnetica by VINCENZO VALENZI, S. GRIMALDI., GIUSEPPE QUARTIERI, G. E. GIGANTE, G. MONACO, GRAZIANO MILETO
(“Ricerca Aerospaziale” 2005)
pag. 33
2
Management of the neurovegetative dystonias in microgravity. First
results of the ”look and see” involving mineral water by Vincenzo VALENZI and COLL.
pag. 38
SEP variations on subjects with chronic constipation in idropinic
treatment by A. PISANI, V. VALENZI et al.
pag. 40
A proposito del campo informatico del potenziale vettore by V. VALENZI
pag. 41
Rassegne e convegni internazionali
pag. 43
News from CIFA
pag. 53
Il cinque per mille per la biometeorologia CSB - Codice fiscale 05751781005
pag. 54
ADDRESS
CIFA NEWS - Centro Studi di Biometeorologia onlus
00192 ROMA - Via Caio Mario 6/a
TEL. : (+39) 339 8865570 – EMAIL : [email protected]
SITO : www.cifa-icef.org
3
EDITORIAL
EDITORIALE
2007 is gone but something has changed...
Whilst entering the 2008 spring time we can affirm that the year 2007 has been an year very
rich of “coupe de theatre” influencing the development of contemporary science. In the meantime, 2008 year remeber to us the big cosmic
cycles governing seasons plus biologic and cronobiologic processes whose topics have been the
focus of the VII CIFA Conference on “Cosmos
and Biosphere” held in Sudak-Crimea, being well
reported down below in this number.
We did started with the BIOMET ‘07 parabolic
flight from Cape Canaveral trying to be acquainted with biometeorology dynamic management of micro gravity.
Later, it (myself) has been founded the Institute
of Biometereology and Space Medicine in Lugano
at the L.U.de.S. University. During the short period of my management, a lot of scientific activities, meetings and workshops have been organised and hold. For example, just seeing on the
web site of “Novaenergy”, you can read:
http://www.novaenergy.it:80/ Vacuum and
Coherence in Nature: the legacy di Giuliano
Preparata, the conference for the presentation
of the Benveniste Archivies held in LuganoL.U.de.S.
http://www.vglobale.it/NewsRoom/index.php?Ne
ws=3731&ref, the conference at Sudak that has
signed the reentry to the honours of the Jacques
Benveniste science after that the “ignoble IgNobel” was assigned to Benveniste by a wearied
and tired old fashion scientific world and Community trying to kill him with ridiculous experimental and theoretical facts that, during the
subsequent years, have indeed been expression
of a formidable development based upon the
strambling and surprising big electronics progresses that really had been a great pulse to the
scientific and technological development processes.
Last but not least in 2007, due to Macroedizioni
press, it was published in Italy a volume on the
W. Reich works
http://www.agenziafuoritutto.it/Seconde%20pag
ine/n.42%20-%202007/reich.htm.
Actually, this book has opened again the “ether”
scientific question, the thermodinamic and the
character analysis topics that used to be considered already well closed by more then 50 years
ago with the classic middle age story about closing the cell and throw away the key supported
by burning books events.
Actually, the very many tentative of opposition
to a serene scientific evaluation of the Austrian
scientist have all broken due to the emergency
inside the Scientific Community of the selfconsciousness of the obscure energetic question –
the so called “obscure energy” question – and
Il 2007 è passato e qualcosa è cambiato…
Mentre entriamo nella primavera del 2008 (che
ci ricorda i grandi cicli cosmici che presiedono alle stagioni e all’andamento dei processi biologici
e cronobiologici che sono stati al centro della VII
Conferenza del CIFA “Cosmo e Biosfera” a Sudak
in Crimea di cui trovate un lungo report a seguire), possiamo affermare che il 2007 è stato un
anno ricco di colpi di scena destinati a incidere
sullo sviluppo della Scienza contemporanea.
Abbiamo iniziato con BIOMET ‘07 un volo parabolico da Cape Canaveral dove abbiamo preso
confidenza con il management delle dinamiche
biometeorologiche in condizioni di microgravità.
E’ stato fondato alla Ludes di Lugano un Istituto
di Biometeorologia e Medicina Spaziale che, nella
sua breve vita sotto la mia direzione, ha svolto
attività di rilievo come il meeting sulla webtv di
Novaenergy
http://www.novaenergy.it:80/ Vacuum and
Coherence in Nature:the legacy di Giuliano
Preparata, alla conferenza per la presentazione
degli Archivi Benveniste a Lugano
http://www.vglobale.it/NewsRoom/index.php?Ne
ws=3731&ref, alla conferenza di Sudak che ha
segnato il rientro con gli onori del caso di Jacques Benveniste nella scienza, dopo gli ignobili
Ig Nobel che un mondo scientifico logorato, ha
pensato di assegnare a Jacques illudendosi di
poter uccidere con il ridicolo fatti sperimentali e
teorici che negli anni successivi hanno visto uno
sviluppo formidabile, complice il dilagare dei
progressi nell’elettronica che hanno accelerato
tutti i processi scientifici e tecnologici.
Last but not least per i tipi di Macroedizioni è
stato pubblicato in Italia un volume sull’Opera di
W. Reich,
http://www.agenziafuoritutto.it/Seconde%20pag
ine/n.42%20-%202007/reich.htm che ha di fatto
riaperto le questioni scientifiche dell’etere, della
termodinamica e della analisi del carattere che
erano state chiuse di forza cinquantanni fa con la
chiave di una cella e un falò di libri, che ricordarono tristemente i tempi del medioevo.
I tentativi di opporsi ad una serena valutazione
scientifica dell’opera dello scienziato austriaco si
sono infranti davanti all’emergenza nella comunità scientifica della consapevolezza della oscurità
della questione energetica (la cosiddetta energia
oscura) e davanti ad una nuova generazione di
ricercatori che hanno avuto la possibilità di riflettere e di osservare negli ultimi quarantanni fenomeni sperimentali e vuoti teorici che rendono
la questione energetica posta da Reich tutt’altro
che figlia della fantasia più o meno deviata.
In un’epoca come la nostra dove scienza e antiscienza combattono gomito a gomito (nelle pagine dei giornali e sulle televisioni) e dove i confini tra il bene e il male sono sempre più labili,
4
due to new outcomes of new generation researchers that have had the opportunity to reflect and observe last four decades experimental
phenomena plus some theoretical incongruence’s
that have given to the question placed by Reich
that are really and fruct of fantasy.
At this stage of our human development, science
and ant science fight each other by using “media” (radio, TV, newspapers and other means)
whilst the demarcation between good and bad is
always very little in such a way that it come out
notable and interesting to repeal the big lesson
given by F. Nietziesche on his “Method”.
Actually, from his book “Human too much human” it is possible to read the following: “Globally, the scientific methods are the results of important research at least equal to any other results: actually, the scientific spirit is based on
the method knowledge and, if those methods
could go lost, all the science results could not
avoid a renewed superstition and nonsense
propagation. People of Spirit could learn as much
as possible from science results: from their talks
and, mainly, from the hypothesis included in the
same talks it could be always noted the lack of
scientific spirit: they have'nt got that instinctive
mistrust toward thinking vacuities and failures in
such a way that, after a long period of exercise,
have stricken root in the mind of every scientist.
Generally, it is enough for them to find any kind
of hypothesis concerning one single thing to become enthusiastic and think that, with this finding, everything has been made. To them, having
an opinion just means to become fanatics and
set it in the hart as a firm belief. Facing an unclear and unexplained topic, those people burn
out for the first idea coming up to their mind and
that seems equal to an explanation: from this
approach, always are produced, specially in the
political field, the worst consequences. Due to
this, nowadays, everyone should have learned at
least one science from the very fundamentals:
so he should know what really is the method and
how much necessary is the maximum reflexion”.
Whilst the scientific challenge on the earth and
space frontiers of the life become even more fascinating it should be useful remembering the
German philosopher lesson by taking properly
into account that the “mission” of scientists is
the research of the truth and the service to the
Humanity such has been made by Sabino Palmieri whose commemoration will be held on 23th
at the Third University of Rome. Humanity is
waiting to receive from scientists new solutions
to severe old and many theoretical and practical
problems persisting in our world sometime more
than that coming from the outer space, Moon
and Mars conquest.
VINCENZO VALENZI
(CIFA President)
ritorna utile la grande lezione di F. Nietziesche
sul Metodo.
Dal suo libro Umano troppo Umano possiamo
leggere: "In complesso i metodi scientifici sono
un risultato della ricerca importante almeno
quanto qualsiasi altro risultato: sulla conoscenza
del metodo si basa infatti 1o spirito scientifico e,
ove quei metodi andassero perduti, tutti i risultati della scienza non potrebbero impedire un rinnovato dilagare della superstizione e dell'insensatezza. Le persone di spirito possono imparare
quanto vogliono dai risultati della scienza: dalla
loro conversazione, e soprattutto dalle ipotesi in
essa contenute, si noterà sempre che mancano
di spirito scientifico: non possiedono quell'istintiva diffidenza verso gli erramenti del pensiero la
quale, in seguito a un lungo esercizio, ha messo
radici nell'anima di ogni uomo scientifico. In genere ad esse basta trovare su una cosa un'ipotesi qualsiasi per entusiasmarsene e pensare che
con ciò sia fatto tutto. Per esse, possedere un'opinione già significa diventarne fanatici e riporsela da allora in poi in cuore come convinzione. Di
fronte ad una cosa non spiegata, si riscaldano
per la prima idea che vien loro in mente e che
assomigli ad una spiegazione: dal che si producono di continuo, specie nel campo della politica,
le peggiori conseguenze. Per questo oggi ciascuno dovrebbe aver imparato sin dalle basi almeno
una scienza: allora saprebbe che cosa sia un metodo e quanto necessaria sia la massima riflessione”.
Mentre la sfida scientifica sulle frontiere della vita sulla terra e nello spazio diventa sempre più
affascinante, è utile ricordare la lezione del filosofo tedesco, memori che la mission degli uomini
di scienza è la verità e il servizio all’Umanità
(come ha fatto Sabino Palmieri che ricordiamo il
23 di aprile all’Università RomaTre), che si attende dagli scienziati nuove soluzioni ai molti
problemi teorici e in particolare pratici più o meno gravi che persistono nel nostro mondo e molto di più in quelli che ci accingiamo a conquistare
negli spazi siderali, dalla Luna a Marte.
VINCENZO VALENZI
(Presidente del CIFA)
5
CONFERENCES. VII International Conference
“COSMOS AND BIOSPHERE:
Cosmic Weather
and Biological Processes”
The Resolution of the 7th International Crimean Conference “COSMOS AND BIOSPHERE”
(October 1 – 6, 207, Sudak, Ukraine)
T
he participants of the conference «Space and biosphere» mark that development and changes of
biosphere, climate and environment on our planet takes place in the conditions of the continuous influencing of different space factors that control by variations of solar activity. The presence of such influencing is first systematized and scientifically grounded by Alexander Chizhevsky, 110-years from
the day of birth of which celebrate a scientific association in 2007.
Presently the influence of space weather on biosphere processes does not cause a doubt and the researches on this direction are conducted scientists of different countries. A long time ago this scientific
direction on the study of dependence of climatic changes, geophysical and biological processes from a
space weather in the nearest surroundings of Earth was formed.
The influence of space factors, in particular of solar activity, on a biosphere is multi-channel.
Therefore a study and design of biological efficiency of physical factors, near to the natural parameters, requires careful researches. It is important to use the scientifically-grounded approaches to the
study of displays of this influencing and transformations of changes of space weather to the changes of
ecological parameters of environment, included geomagnetical, electric, acoustic, gravitation and other
fields, in the changes of level electromagnetic radiations of different ranges on a earth surface, in an
atmosphere and other geospheres of Earth.
The participants of conference underline the necessity of continuation of researches and said of therow
of initiatives and propositions, in particular:
1. To continue works on creation of compatible methods of treatment of the data of parameters of
space factors, geophysical fields and biological processes for revealing of the reliable and scientificallygrounded regularities and correlations. To consider extraordinarily important the conducting of synchronous space and surface experiments with the purpose of capture of data about the changes of
space factors and proper biological, climatic, ecological and other effects, where the space influencing
shows up. In this connection the International Project «BIOCOS», developed professor Franz Halberg
(The USA, Minnesota) (http://www.msi.umn.edu/~halberg/)
and project «GELIOMED» (http://www.geliomed.kiev.ua/), developed the group of the Russian and
Ukrainian researchers is one of important directions of researches of space-biosphere phenomena.
2. To approve the efforts of research of ISRICA and SCSEM of RAS on evaluation of the biological effects of sun eclipses. To support the research project «Eklips-2008» (leader of project Alexander
Trofimov, Novosibirsk, Russia).
3. To continue the researches on development of methods of prognostication of changes of space factors and proper reactions on them earthly objects.
4. To consider extremely important the co-ordination of efforts of specialists from the different areas
of science and also from different countries with the purpose of development of scientific fundamental
and applied questions within the framework of problem «Space and biosphere».
Their support has the special meaningfulness from the side of government and non-government institutions. In this connection the participants of conference support the idea of organization within the
framework of activity of Ukrainian Biophysical Society of the Work-Group «Space and Biosphere» the
main task of which must be co-ordination of researches in Ukraine in area of solar-biosphere connections.
5. For co-ordination of works and effective conducting of synchronous experiments the creation of informative resources is needed (WEB-sites, including both the public data-bases on solar activity, dynamics of biological, ecological, geophysical and meteorological processes). Works in a collaboration
will allow to unify methods, produce the criteria of estimation of space influence on living organisms.
6. Present data array testifies that the experimental verification of hypotheses about influence of extremely weak physical and chemical factors on the biological systems is important and perspective direction in the study of solar-biosphere connections.
The decision of this question requires development of on principle new theoretical and methodological
6
approaches in which water and water environments can be examined as primary «sensory» of weak
influences.
7. The participants of the Conference support efforts of CIFA on integration of interdisciplinary researches in area of heliobiology, biometeorology, climatology and space medicine.
8. To carry out the work on creation in Ukraine of the Interdepartmental scientific Council of problem
«Space and biosphere» and similar councils in other countries, where researches are conducted on this
problems (possibly, with the prospect of creation of international association of scientists).
9. The activities connected with the 110th anniversary of birth day of Alexander Chizhevsky is an actual and important task in context of study of creation and biography of scientist. Using vast informative material, got at edition of works of these measures, it is necessary to prepare general data-base
in the electronic type (on a DVD-disk and in a network the Internet) that additionally can include the
scientific articles and materials, related to personality and activity of Alexander Chizhevsky.
10. To appeal to the central organs of power of countries, to national academies of sciences, space
agencies and hydrometeorological centers, and also to the academies of medical sciences, ministries of
health, ministries on extraordinary situations and other organizations and departments that coordinate the researches of both space and biosphere, climate and environment with a request about
organizational and financial support of space-biosphere researches.
Chief of the Program Committee: BORIS VLADIMIRSKY
Chief of Organizing Committee: VICTOR MARTYNYUK
Protocol of the Special Session of the 7th International Crimean Conference
“Cosmos and Biosphere” devoted election of new guidance of CIFA
Chairman of Session:
VINCENZO VALENZI
Present:
The member of Program Committee
B.M. VLADIMIRSKY (Ukraine), L. GALL (Russia), M. Miroshnichenko (Ukraine), N. Temuryants (Ukraine), V. Voeikov
(Russia)
The member of Organizing Committee
V. MARTYNYUK (Ukraine) (Chairperson), E. CHUYAN (Ukraine), A.
DROZDOV (Russia), M. LYCHAK (Ukraine), M. TRUBINA (Russia),
YU. TSEYSLYER (Ukraine), V. VALENZI (Switzerland), T. ZENCHENKO (Russia)
The participants of Conference
65 persons
Total
78 persons
Listened:
1. President CIFA, prof. BORIS VLADIMIRSKY
Prof. B.M. Vladimirsky shortly reported that a lot of years he heads scientific society of CIFA formal. He considers that came time to renew guidance of this organization, therefore he tenders
resignation. He suggested to support the candidature of Vincenzo Valenzi on the post of President
of CIFA. According to his the opinion Vincenzo Valenzi is one of the most active members of CIFA.
He has more administrative and financial possibilities for adjusting of active work in frame of CIFA.
2. Member of CIFA, prof. VINCENZO VALENZI
Vincenzo Valenzi. thanked to B. Vladimirsky for his personal contribution to work of CIFA. Vincenzo Valenzi also thanked to B. Vladimirsky for the high estimation of the personal contribution of
Vincenzo Valenzi to CIFA. He suggested to choose Boris Vladimirsky on position of the Honoured
President of CIFA.
7
3. Member of CIFA, VICTOR MARTYNYUK
V. Martynyuk paid attention of participants of the Conference on good organizational abilities of
Vincenzo Valenzi and his important contribution to organizing of the Conference. Victor Martynyuk
suggested to support a candidature of Vincenzo Valenzi on position of President of CIFA.
4. Member of CIFA, prof. VINCENZO VALENZI
He offered on the position of Vice-President candidature of Piero Faraone and Victor Martynyuk
and also on position of the General Secretary – Paolo Manzelli. Vincenzo Valenzi asked particpants
of еру Сonference about other suggestions.
Another suggestions were not.
Vincenzo Valenzi asked participants of conferences about form of voting – personal or by a list suggested candidatures.
The participants of conference accept a decision to vote by list and by free vote by raising of hands.
The result of voting:
“agree” – 75.
“not agree” – not.
“did not vote” – 2.
According to results of voting:
VINCENZO VALENZI - the new President of CIFA
BORIS VLADIMIRSKY - the Honored President CIFA
PIERO FARAONE – Vice-President of CIFA (presents the European Community)
VICTOR MARTYNYUK - Vice-President of CIFA (presents the Euro-Asian Communities)
PAOLO MANZELLI – General Secretary of CIFA
Chief of Organizing Committee
of the 7th International Crimean Conference
“Cosmos and Biosphere”
V.S. MARTYNYUK
AWARD BENVENISTE
The Protocol of the Session of Awarding Committee
of the 7th International Conference”COSMOS AND BIOSPHERE” .
1. The Program and Organizing Committee on 7th International conference “Cosmos and
Biosphere” accepted a next decision - to form a Work Award Committee (WAC) of five persons from the participants of conference for Benveniste Association Awarding of the best
reporter. The Committee composition is foloow:
1. V.VALENZI (Lugano, Switzerland);
2. B. VLADIMIRSKY (Simferopol, Ukraine);
3. L. GALL’ (Sankt-Petersburg, Russia);
4. N. TEMURYANTS (Simferopol, Ukraine)
5. A. TROFIMOV (Novosibirsk, Russia)
The members of WAC elected the Chairman – L. GALL’ (Sankt-Petersburg, Russia)
2. The members of WAC after discussion accepted the next criteria for awarding:
a) the reported scientific works must be devoted a study of mechanisms of influence of low intensity
factors on biological system;
b) the basic idea of the reports - water as the “sensor” of low intensity physical and chemical factors;
c) the results of works must explain possible mechanisms of influence of cosmic weather on biological
and physic-chemical processes;
d) the works must be perspective for future investigations.
8
3. WAC made a decision to reward the followings participants of the Conference:
ONE FIRST PREMIUM – 1000 USD TO AWARD
VLADIMIR VOEIKOV for report “KEY ROLE OF WATER AND CARBONATES IN RESPIRATION” (coauthors: N. D. VILENSKAYA, S. I. MALISHENKO, K. N. NOVIKOV - Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia, E-mail: [email protected] ).
TWO SECOND PREMIUMS – 700 USD to award:
GRIGORI ANDRIEVSKY for report “WATER STRUCTURES ORDERED BY THE SPECIFIC MANNER
AS UNIVERSAL REGULATORS OF BIOLOGICAL PROCESSES: WHAT HYDRATED FULLERENES –
THE SYMBIOSIS OF PURE CARBON AND WATERS - HAVE TOLD ABOUT IT? (ISMA NAS Ukraine,
STC “Institute for Single Crystals”, Kharkov, Ukraine http://fullwater.com.ua
E-mail: [email protected])
SERGEI ZAGUSKIN S.L. for report “RHYTHMS OF PHASE SOL-GEL TRANSITIONS IN THE CELL,
CONDITIONS OF THE BIORESONANCE AND STABILITY TO EXTERNAL INFLUENCES” (Southern
Federal university, Rostov - on-Don, Russia, E-mail: [email protected] , www.febz.ru)
TWO THIRD PREMIUMS – 500 USD to award:
GALINA ZUBAREVA for report “THIN WATER LAYERS AS ETHANOL SENSOR” (Tver State Medical
Academy, Tver, Russia, E-mail: [email protected])
VICTOR MARTYNYUK for report “EXPERIMENTAL VERIFICATION OF “ELECTROMAGNETIC HYPOTHESIS” OF SOLAR-BIOSPHERE CONNECTIONS” (co-author N. A. TEMURYANTS, TARAS
SHEVCHENKO, National University of Kyiv, Kyiv, Ukraine E-mail: [email protected]; V. VERNADSKY, Taurida National University, Simferopol, Ukraine, E-mail: [email protected])
FIVE ENCOURAGING PREMIUMS – 400 USD to award:
SVETLANA ROGACHEVA for report “MODELS OF CELL SURFACES FOR THE STUDY OF MECHANISM OF BIOLOGICALLY ACTIVE SUBSTANCES EFFECT IN LOW CONCENTRATIONS” (coauthors Z. A. ZABRODINA, S. A. DENISOVA, P. E. KUZNETSOV, A. U. SOMOV, Saratov State University, Saratov, Russia, Saratov Military Institute of Biological and Chemical Safety, Saratov, Russia, Email: [email protected])
ANDREI DROZDOV for report “ELECTROCONDUCTIVITY AS THE INDEX OF WATER SYSTEM”
(Analitical Device Development Instittute, Sankt-Petersburg, Russia, E-mail: [email protected])
GALINA TARADINA for report “THE STUDYING OF THE INFLUENCE OF PHYSICAL CHARACTERISTICS OF THE VIBRATION ON INACTIVATION OF CATALASE IN SOLUTIONS” (co-author O. I.
DOTSENKO, Donetsk national university, Donetsk, Ukraine, E-mail: [email protected])
IVAN STEPANYUK for report “NEGATIVE INFLUENCE OF ELECTROMAGNETIC CONTAMINATION
ON WATER BIOCENOSES” (Russian State Hidrometeorological University, S.Pb., Russia, E-mail:
[email protected])
VLADIMIR TSETLIN for report “ABOUT TIME VARIATIONS OF CURRENTS OF CONDUCTIVITY OF
WATER IN THE ELECTROCHEMICAL CELL” (co-authors A. A. ARTAMONOV, V. A. BONDARENKO, I,
V, FEDOTOVA, The State Centre of Science of the Russian Federation – The institute of biomedical
problems of the Russian Academy of Science, Moscow, Russia, E-mail: [email protected])
Chief of Program Committee
of the 7th International Conference “Cosmos and Biosphere”,
scientific secretary of Ukarinian Biophysical Society
VICTOR MARTYNYUK
9
Non invasive evallu
uation of pulse wave velocity (PWV)
and endothelial dysfunction (ED)
by YURI GURF
FINKEL
(Clin
nical Hospiital JSC “Ru
ussian Railw
ways and
Spa
ace Research
h Institute, RAS
R
Moscow
w, Russia)
A
theroscleros
sis, a disease of the la
arge arterie
es, is a prog
gressive dis
sease chara
acterized by the accum
mulatio
on of lipids and fibrou
us elements
s. The entire cardiova
ascular system is line
ed by a thin
n layer of cells
c
known as the vascular endothelium
m. With its intercellular tight junc
ctional com
mplexes, the endothelium
ctions as a selectively
y permeable barrier between blo
ood and tiss
sues. Very
y early in the atheros
sclefunc
rotic
c process, before ov
vert lesions
s are evide
ent, it is possible
p
to demonstrate importtant functio
onal
changes within
n the arterial endothe
elium. The endothelium has a powerful efffect on bloo
od vessel tone
t
g, and secre
etes chemicals and otther
and regulates blood flow, adjusts coagulation and blood thickening
n. It also plays an imp
portant role
e in the develsubstances in response to wounds, infections or irritation
ment of carrdiovascular disease. Investigation of arte
erial stiffness, especia
ally of the large arterries,
opm
has gathered pace in rec
cent years with the developmen
d
nt of readily
y available noninvasiv
ve assessm
ment
tech
hniques. Th
hese include
e the meas
surement of
o pulse wa
ave velocity
y and endothelium fun
nction . He
ere,
we describe ea
ach of these
e technique
es.
We also consider that th
his techniqu
ue might be
b most app
propriate fo
or wider cliinical applic
cation. Fina
ally,
the effects of current
c
and
d future cardiovascula
ar drugs on
n arterial sttiffness are also discus
ssed, as is the
relationship be
etween arte
erial elasticity and end
dothelial fun
nction.
ng specially
y designed
d device (A
AMDT, Rus
ssia) for no
oninvasive evaluation
n of pulse wave velo
ocity
Usin
(PW
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11
Bakken's prehabilitation in the service
of a budding chronoastrobiology
by FRANZ HALBERG (1), GERMAINE CORNÉLISSEN (1), DEWAYNE HILLMAN (1), ROBERT B.
SOTHERN (1), ELLIS S. NOLLEY (2), LARRY A.
BEATY (2), OTHILD SCHWARTZKOPFF (1), KUNIAKI OTSUKA (3), SERGEI M. CHIBISOV (4),
VINCENZO VALENZI (5), GIANCARLO PANTALEONI (6) e R.B. SINGH (7)
(1) Halberg Chronobiology Center, University
of Minnesota, Minneapolis, MN, US
(2) Phoenix Group, Institute of Electrical and
Electronics Engineers, Minneapolis, MN,
USA
(3) Tokyo Women’s Medical Center East, Tokyo, Japan
(4) People's Friendship University of Russia,
Moscow, Russia
(5) Universita di Roma "La Sapienza", Rome,
Italy
(6) Universita degli Studi de L'Aquila, L'Aquila,
Italy
(7) Halberg Hospital and Research Institute,
Moradabad, India
Abstract
Measurements
of blood pressure (BP) or heart rate (HR) in an office and even ambulatory (A)
around-the-clock profiles at half-hourly or hourly intervals for a few days' ABPHR can lead to unwarranted treatment for a lifespan or may leave people at an avoidable high risk untreated.
Chronobiologically interpreted 24-hour/7-day ABPHR (C24/7) is a temporary substitute for lifelong
monitoring, the latter already implementable from weaning on mice. C24/7 may suffice to rule out abnormality for the given individual, but not to rule it in. When C24/7 detects abnormality, replications
of C24/7 are indicated until the disorder is eliminated. Automatic monitoring, which interferes minimally with waking activities and sleep, is superior to manual C24/7 measurements. C24/7 profiles detect, in the light of a parametric and non-parametric (sphygmochron) analysis, vascular variability disorders, VVDs. These include:
1) high blood pressure (MESOR-hypertension, MH) assessed (not by target values for all adults irrespective of gender and age, but) by the midline-estimating statistics of rhythm (MESOR, M) based on
C24/7 interpreted in the light of (vs) reference standards from peers matched by age and gender
(RS);
2) circadian overswinging, i.e., circadian hyper-amplitude-tension, CHAT, in C24/7 vs. RS,
3) an excessive pulse pressure in C24/7,
4) an odd timing of circadian blood pressure variability (ecphasic circadian rhythm of BP but not of
HR) in C24/7, or 12
5) an under-threshold standard deviation in C24/7 HR.
One VVD can coexist with any other and thus can result in one of several vascular variability syndromes (VVSs). VVDs and/or VVSs may detect prehypertension, prediabetes and a premetabolic syndrome and constitute a stress test; when they coexist, they greatly raise the risk of hard vascular
events. Some VVDs or VVSs can be readily treated, e.g., MH with CHAT, sometimes only by changing
medication timing. Chronobiologic analyses are implemented at several geographic sites, documenting
that CHAT, like MH, is found in all 5 continents. Analyses for automatic self-surveillance in one's health
care are available from [email protected] in exchange for the data that also serve for medical and
transdisciplinary research, including the monitoring of solar variability and thus of space weather.
Objective. To learn about and to optimize accommodations to environments near and far by focus
upon cycles in invisible as well as visible phenomena by self-help in computer-aided preventive prehabilitation, to save the cost of rehabilitation and learn about a transdisciplinary science dealing with The
BIOsphere and the COSmos (BIOCOS).
Background. One of the major contributions of Earl Elmer Bakken, who developed the implantable cardiac pacemaker, is the restoration of a failing heart rhythm. The much broader task of Earl's prehabilitation, Figure 1 (1, 2), is preventing the heart and other organs and tissues (and ecosystems) from
failing. Data collected for prehabilitation are being mapped as chronomes (time structures consisting
12
of deterministic or other chaos and trends organized by rhythms [3-6]).
Chronomes in biological variables serve for the study of underlying mechanisms, the topic of chronobiology [7]). From chronobiology, with its basic physiological, diagnostic, therapeutic and ecological
branches, chronomics originated; it maps cycles in us aligning them with those outside us to look for
congruent environmental and biological periods, with overlapping or overlying uncertainty estimates of
their periods. Methods to investigate and uncover associated time-varying biological and environmental cycles represent the tools for a globally extended view of health and ecology (8) for a chronoastrobology.
Figure 1
Pre-habilitation, preferably
before as well as with or after
rehabilitation (for further vascular disease prevention and
more generally). By the early
detection of disease risk
syndromes in the individual
subject, countermeasures for
primary prevention can be instituted. Such pre-habilitation
in health can also complement
rehabilitation in disease and
can be a major goal of health
care. Pre-habilitation would
complement an across-theboard reduction of risk factors, the latter implemented
by changes in lifestyle.
Interest in both the associations of the biosphere with its cosmos and in prehabilitation (1, 2) led to
activities including retrospective analyses of archived data from governmental health and other departments, and further analyses of prospectively, as-one-goes, accumulating data from participants on
different continents in the BIOCOS project (9-11; cf. 12).
This endeavor focuses preferably on longitudinal, decades-long, if not yet on lifetime-covering time series of blood pressure, heart rate and other variables and as a minimum on 24-h/7-day records. BIOCOS now makes analyses available free of charge worldwide, including summaries of systematically
collected time series allowing assessment, e.g., of blood pressure and heart rate variability interpreted
in the light of reference values in health (in a sphygmochron). The same data are also made available
for purposes of research, and thus, i.a., for updating and improving, as analyses progress, both the
reference data base and the analysis software. Thereby, all data can eventually be compacted for a
usable summary in a transdisciplinary atlas that represents the complementary control information for
manufacturers of devices (13) and everybody else undertaking the study of a variable as a function of
time.
Currently, BIOCOS is a group of participants from different disciplines and walks of life, including family practitioners of medicine and the general public engaged in preventive health care by detecting, on
the one hand, otherwise silent variability disorders (that can carry a risk of severe diseases such as a
stroke, greater than the risk associated with a high blood pressure). On the other hand, once this diagnosis of an alteration in variability (for prehabilitation) or that of a rigorously validated high blood
pressure (MESOR-hypertension) is established, BIOCOS provides sequential as-one-gone analyses for
13
those self-surveilling long-term participants under treatment by care providers. These participants and
others, who are interested primarily in the effects of the cosmos on the biosphere, have used the data
accumulated thus far to find not only a new spectrum of biological cycles but also differential congruences in the form of differing overlying or overlapping 95% confidence intervals among the biological
periods, among those of environmental counterparts, and among those of the biosphere and of its
cosmos.
By a novel microscopy in time (a combination of gliding and global spectra with chronobiological serial
sections and their summary by population-mean cosinor), we resolve the invisible solar wind's mimicry
in biomedicine. In the past half-century it has become better known that the visible environmental day
or year are built into us (14). In the last decade, we have learned about many invisible natural physical and some new and old biological oscillations, the old ones with new 95% confidence intervals of
their periods.
There are, among others, biological near-matches to invisible, e.g., magnetic cycles of about (~) 7
days (15) shown by Vladimirsky for aa (16), parts of the Cornélissen-series (17), along with cycles of
~0.42, 1.3 and 1.6 years reported in solar wind speed, among many other cycles, some shorter (cis =
on this side of) or longer (trans = beyond) the length of a calendar year, i.e., cisyears or transyears,
respectively. For notably newborn and elderly human blood pressure and heart rate, as for adult sudden cardiac death in certain, not all, geographic areas (11), cycles with a period longer than a calendar year can be more prominent in amplitude than the calendar year related to the seasons and/or society.
Ontogenetic and comparative evidence suggests that novel physiological rhythms constitute a system
of common transdisciplinary spectra in time structures, prevailing as vestiges early in life but much
less so during maturity, when physiological counterparts of photic cycles coexist and compete with
those of non-photics.
In the endeavor to document these new horizons, BIOCOS provides free analyses in exchange for
data, with help from members of the Phoenix Project, a Minnesota group of members of the Institute
of Electrical and Electronics Engineers (IEEE; http://www.phoenix.tc-ieee.org). The latter are creating
for BIOCOS an eventually international, multilingual website (http://www.sphygmochron.org/) to enable a self-help-based automatic individualized inferential statistical diagnosis and treatment surveillance and in the data so collected, notably if they continue to accumulate worldwide a study of geographic differences in the signature of solar variability in health and disease can be undertaken. Figure
2 shows plans for this website's objectives.
Individuals venturing into space with responsibilities essential to a mission should be best screened for
their own and their mission's safety (18, 19). For the sake of science, astro- or cosmonauts should collect data on earth as control for their time series in extraterrestrial space. There is an opportunity to
detect new variability disorders that are unrecognized with conventional screening and that can be
treated as the start of a yet broader prehabilitation, a self-help-based preventive as well as curative
health care. While it is of particular pertinence for those venturing into space, prehabilitation's immediate spin-offs on earth, in the service of an extended view of health and ecology (8), can tear down
disciplinary barriers (20) while also analyzing the effects of space weather (1 , 2 , 21), Fig.2
14
Figure 2.
The Phoenix Group of
volunteering
members of the Twin Cities chapter of the Institute of Electrical
and Electronics Engineers
(http://www.phoeni
x.tc-ieee.org)
is
planning on developing an inexpensive,
cuffless
automatic
monitor
of
blood
pressure and on implementing the concept of a website
(www.sphygmochron
.org). © Halberg.
The paradox of more for less can be realized by computer-aided self-help in preventive health care by
prehabilitation. This endeavor can start with the detection of variability disorders that represent risks
greater than hypertension, yet can be associated with values that are all in the normal range of variation (a useful concept that nonetheless draws a curtain of ignorance over everyday physiology). If the
"curtain" is drawn, risk detection can be done as early as possible, certainly with the passive audiences
in late primary and early secondary education (22). For this purpose minimal data requirements and
minimal analytical steps have to be specified. Given such standards, an automatic website can provide
a free service and achieve a second paradox, namely data collection on a broad basis for monitoring as
a dividend from self help in health care the effect of solar weather, Figure 2. Evidence has been presented to show that in the case of blood pressure the status quo is untenable and that current shortcomings can be readily overcome by an international consensus (23) which broadens the view of
health and ecology (8) by focus upon an increasingly detailed time structure in us, to be summarized
in an atlas first, and by the effects of space weather upon us, to be mapped concomitantly thereafter.
1.
Cornélissen G, Halberg F, Schwartzkopff O, Delmore P, Katinas G, Hunter D, Tarquini B, Tarquini
R, Perfetto F, Watanabe Y, Otsuka K. Chronomes, time structures, for chronobioengineering for
"a full life". Biomed Instrum Technol 1999; 33: 152-187.
2.
Halberg F, Cornélissen G, Otsuka K, Katinas G, Schwartzkopff O. Essays on chronomics spawned
by transdisciplinary chronobiology: Witness in time: Earl Elmer Bakken. Neuroendocrinol Lett
2001; 22: 359-384.
3.
Halberg F, Cornélissen G, Otsuka K, Schwartzkopff O, Halberg J, Bakken EE. Chronomics. Biomedicine & Pharmacotherapy 2001; 55 (Suppl 1): 153s-190s.
4.
Halberg F, Cornélissen G, Schack B, Wendt HW, Minne H, Sothern RB, Watanabe Y, Katinas G,
Otsuka K, Bakken EE. Blood pressure self-surveillance for health also reflects 1.3-year Richardson solar wind variation: spin-off from chronomics. Biomedicine & Pharmacotherapy 2003; 57
(Suppl 1): 58s-76s.
5.
Halberg F, Cornélissen G, Regal P, Otsuka K, Wang ZR, Katinas GS, Siegelova J, Homolka P,
Prikryl P, Chibisov SM, Holley DC, Wendt RW, Bingham C, Palm SL, Sonkowsky RP, Sothern RB,
Pales E, Mikulecky M, Tarquini R, Perfetto F, Salti R, Maggioni C, Jozsa R, Konradov AA, Kharlitskaya EV, Revilla M, Wan CM, Herold M, Syutkina EV, Masalov AV, Faraone P, Singh RB, Singh
RK, Kumar A, Singh R, Sundaram S, Sarabandi T, Pantaleoni GC, Watanabe Y, Kumagai Y, Gubin
D, Uezono K, Olah A, Borer K, Kanabrocki EA, Bathina S, Haus E, Hillman D, Schwartzkopff O,
Bakken EE, Zeman M. Chronoastrobiology: proposal, nine conferences, heliogeomagnetics, transyears, near-weeks, near-decades, phylogenetic and ontogenetic memories. Biomedicine &
Pharmacotherapy 2004; 58 (Suppl 1): S150-S187.
15
15
6.
Halberg F, Cornélissen G, Bingham C, Witte H, Ribary U, Hesse W, Petsche H, Engebretson M,
Geissler H-G, Weiss S, Klimesch W, Rappelsberger P, Katinas G, Schwartzkopff O. Chronomics:
Imaging in time by phase synchronization reveals wide spectral-biospheric resonances beyond
short rhythms. ("Wenn man über kurze Rhythmen hinausgeht") In memoriam – lost future: Dr.Ing. habil. Dr. rer. nat. Barbara Schack: 1952-2003. Neuroendocrinol Lett 2003; 24: 355-380.
7.
Halberg F. Chronobiology. Annu Rev Physiol 1969; 31: 675-725.Kofler WW. The need on a "critical extended evolution related view" of reality as a basis for an "extended view" of health. Science without Borders, Transactions of the International Academy of Science H&E, 2003/2004; 1:
27-54.
8.
Halberg F, Cornélissen G, Otsuka K, Watanabe Y, Katinas GS, Burioka N, Delyukov A, Gorgo Y,
Zhao ZY, Weydahl A, Sothern RB, Siegelova J, Fiser B, Dusek J, Syutkina EV, Perfetto F, Tarquini
R, Singh RB, Rhees B, Lofstrom D, Lofstrom P, Johnson PWC, Schwartzkopff O, International
BIOCOS Study Group. Cross-spectrally coherent ~10.5- and 21-year biological and physical cycles, magnetic storms and myocardial infarctions. Neuroendocrinol Lett 2000; 21: 233-258.
9.
Halberg F. Historical encounters between geophysics and biomedicine leading to the Cornélissenseries and chronoastrobiology. In: Schröder W, ed. Long- and Short-Term Variability in Sun's
History and Global Change. Bremen: Science Edition; 2000. p. 271-301.
10.
Halberg F, Cornélissen G, Katinas G, Tvildiani L, Gigolashvili M, Janashia K, Toba T, Revilla M,
Regal P, Sothern RB, Wendt HW, Wang ZR, Zeman M, Jozsa R, Singh RB, Mitsutake G, Chibisov
SM, Lee J, Holley D, Holte JE, Sonkowsky RP, Schwartzkopff O, Delmore P, Otsuka K, Bakken EE,
Czaplicki J, International BIOCOS Group. Chronobiology's progress: season's appreciations 20042005. Time-, frequency-, phase-, variable-, individual-, age- and site-specific chronomics. J Applied Biomedicine 2006; 4: 1-38. http://www.zsf.jcu.cz/vyzkum/jab/4_1/halberg.pdf.
11.
Cornélissen G, Delcourt A, Toussaint G, Otsuka K, Watanabe Y, Siegelova J, Fiser B, Dusek J,
Homolka P, Singh RB, Kumar A, Singh RK, Sanchez S, Gonzalez C, Holley D, Sundaram B, Zhao
Z, Tomlinson B, Fok B, Zeman M, Dulkova K, Halberg F. Opportunity of detecting prehypertension: worldwide data on blood pressure overswinging. Biomedicine & Pharmacotherapy
2005; 59 (Suppl 1): S152-S157.
12.
Cornélissen G, Benser M, Halberg F. Patterns of incidence of tachyarrhythmias recorded in implantable cardioverter-defibrillators during 2001-2005. Proceedings, 2nd World Congress of Chronobiology, Tokyo, Japan, November 4-6, 2007, submitted.
13.
Halberg Franz, Cornélissen G, Katinas G, Syutkina EV, Sothern RB, Zaslavskaya R, Halberg Francine, Watanabe Y, Schwartzkopff O, Otsuka K, Tarquini R, Perfetto P, Siegelova J. Transdisciplinary unifying implications of circadian findings in the 1950s. J Circadian Rhythms 2003; 1: 2. 61
pp. www.JCircadianRhythms.com/content/pdf/1740-3391-2-3.pdf
14.
Halberg F, Breus TK, Cornélissen G, Bingham C, Hillman DC, Rigatuso J, Delmore P, Bakken E,
International Womb-to-Tomb Chronome Initiative Group: Chronobiology in space. Keynote, 37th
Ann. Mtg. Japan Soc. for Aerospace and Environmental Medicine, Nagoya, Japan, November 8-9,
1991. University of Minnesota/Medtronic Chronobiology Seminar Series, #1, December 1991, 21
pp. of text, 70 figures.
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Vladimirskii BM, Narmanskii VYa, Temuriantz NA. Global rhythmics of the solar system in the terrestrial habitat. Biophysics 1995; 40: 731-736
16.
Halberg F. Historical encounters between geophysics and biomedicine leading to the Cornélissenseries and chronoastrobiology. In: Schröder W, ed. Long- and Short-Term Variability in Sun's
History and Global Change. Bremen: Science Edition; 2000. p. 271-301.
17.
Halberg F, Cornélissen G, Halberg J, Schwartzkopff O. Pre-hypertensive and other variabilities also await treatment. Am J Medicine 2007; 120: e19-e20. doi:10.1016/j.amjmed.2006.02.045.
18.
Cornélissen G, Halberg F, Otsuka K, Singh RB, Chen CH. Chronobiology predicts actual and proxy
outcomes
when
dipping
fails.
Hypertension
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doi:10.1161/01.HYP.0000250392.51418.64.
19.
Roederer JG. Tearing down disciplinary barriers. Eos, Transactions, American Geophysical Union
1985; 66: 681, 684-685.
20.
Roederer JG. Are magnetic storms hazardous to your health? Eos, Transactions, American Geophysical Union 1995; 76: 441, 444-445.
16
21.
Halberg F, Smith HN, Cornélissen G, Delmore P, Schwartzkopff O, International BIOCOS Group.
Hurdles to asepsis, universal literacy, and chronobiology—all to be overcome. Neuroendocrinol
Lett 2000; 21: 145-160.
22.
Halberg F, Cornélissen G, International Womb-to-Tomb Chronome Initiative Group: Resolution
from a meeting of the International Society for Research on Civilization Diseases and the Environment (New
23.
SIRMCE Confederation), Brussels, Belgium, March 17-18, 1995: Fairy tale or reality ? Medtronic
Chronobiology Seminar #8, April 1995, 12 pp. text, 18 figures. URL
http://www.msi.umn.edu/~halberg/
17
Resin ion exchange and fluctuating phenomena
by MARIAGRAZIA COSTA
(L.R.E. – Dipartimento di Chimica – Università di
Firenze - [email protected]).
An interesting study was carried out some years ago at the Department of Chemistry of the University of Florence, under the direction of Giorgio Piccardi. It is known that water softening systems present anomalies in terms of output when water pre-treated with physical conditioners are used.
This phenomenon is predictable given the structure of resin and the mechanism by which ion exchange
occurs because water, with its exceptional qualities, plays a fundamental role in these complex processes.
In our case, physical treatment of water was obtained by stirring using glass bulbs containing a small
quantity of mercury and a rare gas under reduced pressure. We know that with movement, microdischarges of elevated potential and electromagnetic waves at 3-4 KHz, modulated at 10 Hz intervals,
are generated inside these bulbs. The in-column exchange method was selected to provide experimental proof. A differential procedure was employed to eliminate the influence of normal environmental
factors.
“Kastel C300” was the cationic resin selected, composed of an inert aromatic matrix with crossed styrene-divinyl-benzol bonds that owes its exchange activity to active sulfonic groups. Optimal working
conditions were studied for specific aims such as the type of regeneration, contact time, flow velocity,
etc. The water employed for the measurements, with a hardness of exactly 100° F, was obtained from
potable water with controlled composition and with the addition of CaCl2.
Two series of experiments were carried out:
1) The passage of non-treated water in two columns to observe whether they had analogous behaviour.
2) Passage of non-treated water in one column and passage of treated water in the other to highlight any possible difference in behaviour.
The resins’ capacity for exchange (expressed as grams of CaCo3 per litre) was determined by way of
titration with EDTA of the waters before and after passage in the columns. By utilizing the results obtained from the first series of experiments (non-treated water), it was possible to determine the theoretical exchange capacity. The experiments were continued for 17 months and during this time the influence of the physical treatment of the water was highlighted.
Examination of the results reveals the existence of a direct or indirect modification of the ion exchange
equilibrium. The capacity of the resins for exchange varied over time with an oscillating trend.
The figure illustrates that the % between the real and theoretical exchange capacities had a basically
decreasing trend, with clearly notable peaks in March and October. In addition, in the first measurement period the % had positive values, indicating an increase in the exchange capacity in the case
of treated compared to non treated water. Later, negative values were recorded, with a decrease of
the exchange capacity and, finally, positive values were again noted.
Calculation of the average standard error regarding the differences of exchange capacity of the two
columns functioning with normal, non treated water shows how all significant points of the curve obtained with treated water are outside of such error.
These experiments demonstrated how also resin ion exchange can be considered among phenomena
which fluctuate over time. According to Giorgio Piccardi, “fluctuating phenomena” are those phenomena which are shown to be sensitive to “non traditional” environmental variations such as natural electromagnetic fields. It is interesting to note that these types of systems generally demonstrate characteristic trends around the months of March and September, in line with our observations of resin ion
exchange. All chemical-physical systems that present an equilibrium shift or evolution in heterogeneous environments are subjected to fluctuating phenomena. However, to highlight the interference with
non traditional environmental factors, it is necessary to differentiate the system, for example through
physical treatment of water.
188
Varriation ov
ver time of
the
e differenc
ces betwe
een
real and the
eoretical exe
ange
cap
pacity
obo
cha
serv
ved in ca
ationic res
sin
exc
change using phy
ysicallly treated water
REFERENC
CES
19
Results and perspectives of studies of solar-biospheric
connections in the periods of solar eclipse
by A. V. TROFIMOV
(Scientific center of clinical and experimental
medicine SB RAMS - International SRI of cosmic
anthropoecology
Novosibirsk, Russia, [email protected])
Pictures 1 and 2 differently illustrate the same phenomenon, which we have opened in 2002-2004
years (Trofimov A., Devitsin D., 2006). It is the phenomenon of “outstripping” reflection (by means of
GDV parameters) of changes, taking place on the Sun (according to dynamic of solar electrons and
protons) 3 months before energo-events on our planet, by a human (Fig.1) and by water media
(Fig.2). We consider it to be very important discovery, which is until unknown to world scientific community. I
Solar eclipses are specific periods in the solar-earth links; the events, having a direct or indirect response among different biospheric horizons. Solar eclipse may be considered as a periodic planetarygeophysical functional load for human homeostatic systems. It makes it possible for researchers to estimate the level of organism psychophysical dependence on ionospheric-magnetic fluctuations, which
are initiated by eclipses and take place at different stages of individual development, including prenatal ontogenesis.
0,80
Correlation coefficients
0,60
E1k
P1k
P5k
P>30MeV
Pdens
0,40
0,20
0,00
-0,20
-0,40
-0,60
in the day of study
a month later
3 months later
Fig. 1
Feature of correlative dependence of width of GDV-gram spectrumin a group of
healthy persons (n= 39) on intensity of electro proton component of the rays,
registered by GOES-10 satellite during the days of experiment (17, 18.09.02), in
a month (b) and in 3 months (v) after of Kirlian-video survey of fingers of the
left hand at the device “Korrex” (KirlionicsTechnologyos Int. Ltd.).
At studying biotropic effects of the solar eclipse on the 29th of March 2006 in Novosibirsk, it was
shown, that correlations of haemodynamic, rheoencephalographic and other electrophysical parameters in volunteers- healthy persons (n=14) and patients with AH (n=15) with the intensity of protonelectron components of cosmic rays, radio-emanation of the Sun 220 mGc and value of regional Kindex are reliably changed in the main phase of the event (Trofimov A.V. et al, 2007). The authors
(V.Ya.Polyakov, E.V.Sevostyanova, A.G.Gorelkin, D.V.Devitsin, 2007) found individual variations in
low-frequency field of cardiospectrum, levels of AH, REG amplitude, area and spectral density of gazecharged visualization (GCV)-lighting of the blood samples (Fig.3).
Electroconductivity changes in biologically active points (BAP) (µА) most significantly: before eclipse32,0±2,8; during the event - 21,0±3,0, after its end - 25,0±3,1.
20
Fig. 2 - Correlative dependence ( r ) of water sample fluorescence area, taken
19.01.04 on intensity of electron proton component of the cosmic rays, registered on GOES-10 satellite in the range of ±600-700 hours regarding a 5second GDV-video-survey (27.01.04, 17:00) at the device “Korrex” (Kirlionics
Technologyos Int. Ltd.)
Note: 1,2 –electron component of the cosmic rays E 1k, E 2k.
3,4 – proton component of cosmic rays P 5k, P 1k.
defined the range of dependence p<0,005
It is supposed, that fixed dynamic of cosmo-biospheric conjugations may reflect ionospheric-magnetic,
neutron and other heliogeophysical variations, that accompany solar eclipses (Ivanov V.P. et al, 2007;
Antonova V.P. et al, 2006). According to our data the largest increase in arterial pressure was observed 30 minutes after the main phase of the eclipse in those patients with arterial hypertension, who
had experienced the strongest fluctuations of geomagnetic field in the first month after birth. Continuation of the studies in that direction seems actual in the epoch of cosmo-planetary changes.
State SCCEM SB RAMS and ISRICA initiate synchronous, by astronomic time, investigation of the mechanisms of solar-biospheric links on different physic-chemical, biological and physiological models in
the periods before, during and after the total solar eclipse on the 1st of August 2008, in stationary and
expedition-field points, located on the trajectory of supersonic speed movement of moon shadow on
the surface of the Earth, in Novosibirsk, Novosibirsk region, Altai Territory and the Gorno-Altai Republic.
The program of the new global experiment “Eclipse – 2008” and suggestions on its scientific-methodic
provision will be presented to the participants of International conference “Cosmos and biosphere”
with the perspective of their joint realization.
It is supposed to discuss preliminary results of interdisciplinary astronomic, helio-geophysical and medico-biological investigations at the 2nd International symposium “Heliogeophysical factors and human
health” in Novosibirsk in 2010.
500000
450000
400000
350000
Спектральная плотность
300000
V1
250000
200000
V2
150000
100000
V3
50000
0
Частота, Гц
Fig. 3
Spectral density
of GDV fluorescence of blood
sample in examine V. before the
eclipse (V1), at
the
moment of the
eclipse (V2) and
after it (V3).
21
Is the biological test of Colony Sectoring (CSD)
what Piccardi hoped to support his intuitions ?
by PIERO FARAONE
(Vice President of CIFA - Member of International
Accademy of Science in Milano - Past Medical Director of Hygiene Laboratory of Roma)
Il test delle colonie batteriche a settore differenziato (CSD) é il test biologico sensibile che
Piccardi si augurava che si trovasse,
per confortare le sue intuizioni?
SUMMARY
RIASSUNTO
<<... I cannot hope to understand this phenomenology, I’m hardly aware of thisone… Piccardi said in the Biometeorolgy Congress of
Montreux in 1969 and then also said -…… It's
evident that the sensitive systems, and especially the living organisms, can show the deep
things existing in the universe and they can
show them to us much better than physical instruments, being always strictly selective and
therefore unable to notice a general situation.and then -.the tool will be once again a sensitive
system [and therefore eterogeneous, out of his
equilibrium and very complex ] selected among
the most complex sensitive systems in the
world. ] . The word will be left once again to the
study of the fluctuating phenomena and the sciences of life>>.
<<...Non posso sperare di venire a capo di questa fenomenologia appena intravista…….. - questo diceva Piccardi nel 1969 al Congresso di Biometeorolgia di Montreux, e poi -……E' evidente
che i sistemi sensibili, e soprattutto gli organismi
viventi, possono mostrarci ciò che di profondo esiste nell'universo e mostrarcelo meglio degli
strumenti di fisica sempre strettamente selettivi
e perciò incapaci di avvertire una situazione generale. – e poi ancora -.....lo strumento sarà
ancora un sistema sensibile [e perciò eterogeneo, fuori equilibrio e molto complesso] scelto fra i
sistemi sensibili più complessi che esistano al
mondo. La parola sarà ancora una volta allo
studio dei fenomeni.alle.scienze.della.vita.>>.
Thanks to the CSD test, the A. of this lecture
would totally agree with Piccardi intuitions apart
from the belief that the test has to be necessarily a very complex tool. The prerogative of CSD
test is that it has to be only quite complex but it
has to be able to underline the correlations with
the fluctuating phenomena of space physical nature, without suffering too many interferences disturbing a clean development of its temporal rhythms (allowing therefore a more
clear reading of their fluctuations). Not only: it
has to be able to connect life factors with physical strengths of space, which results to us no
longer extraneous but, on the contrary, it may
prove to be able to condition some lifeequilibrium of biological substratum deeply
showing his suffered influencing (mutations ?).
Another prerogative of the mentioned test is to
be a quite simple method in order to allow its
practical implementation. In his lecture, the
A. has tried and ascertained whether the auspices wished by Piccardi have been met, i.e. to
discover a biological test confirming more clearly
the correlations he has studied and, may be,
supplying.further.information. Is the biological
test of Colony Sectoring (CSD) what Piccardi
hoped to support his intuitions?
TEXT
Tchijewsky hypothesized since 1930 a possible
Con il test CSD, l'A. di questo articolo, collimerebbe in tutto con le intuizioni del Piccardi salvo quello di ritenere che il test debba essere necessariamente uno strumento molto complesso.
La prerogativa del CSD test é invece proprio
quella di essere solo abbastanza complesso, capace però di evidenziare le correlazioni con i fenomeni fluttuanti di natura fisica dello spazio,
senza subire troppe interferenze che ne disturbino una lettura sufficientemente pulita dei ritmi
nel tempo ( consentendo quindi una chiara lettura della fluttuazione) e non solo, ma sia pure capace di evidenziare un collegamento fra rapporto
fattore vita / forze fisiche dello spazio, e di
quest’ultime la presenza di un condizionamento di equilibri vitali, lasciando nel profondo del
substrato biologico la testimonianza delle influenze causate (mutazioni ?). Altra prerogativa
del test è quella di essere un mezzo abbastanza
semplice per consentire una facile metodica per
la sua attuazione pratica. L'A. ha cercato di appurare, nella sua esposizione, se sia riuscito a
coronare gli auspici che Piccardi si augurava che
si realizzassero e cioè di trovare un test biologico
che ne confermasse con maggiore chiarezza, le
correlazioni da lui studiate e che potesse indicare
magari, qualcosa in più.
TESTO
Tchijewsky ipotizzò fin dal 1930, una possibile
correlazione tra fenomeni biologici e attività solare. Egli realizzò lunghe e accurate indagini nel
22
correlation between biological phenomenons and
solar activity. He realized long and accurate in
estigations in the first one '900 ascertaining
trough epidemiological data, that some epidemics followed entirely a cyclical course analogous
to course of the solar activity( Wolf Number). Infectious illnesses as the diphtheria, the plague
the cerebrospinal meningitis, the typhus, the
smallpox and so forth , had the peak epidemic in
correspondence of that of the solar activity that
would have acted as factor of real biological excitement.
Only in 1965 however, one year after his death ,
its studies were recognized of considerable scientific value, from a prepared Committee of the
Academy of the Sciences of USSR.
Since 1935 it had been noticed by various researchers that the water for some its property, if
submitted to some actions of physical nature, in
different times didn't show always an equal answer of same intensity; such property was said
semipermanent (Communication of Piccardi to
the Confer.of Montreux,1969).
In 1939 it was advanced the hypothesis that
such mutable replies were to connect with phenomena acting in the space.
Piccardi later a few years would have supported
the genial hypotheses of the Russian researcher
Tchijewsky, with his experimental data. In
1951,in a general phase of arid hypotheses, Piccardi decided to pass to an experimental verification through the colloidal test from him devised.
This simple revealing system was sufficiently
sensitive to pick up signals coming from not traditional (or spatial) variables as the Att.Solare,
the Att. Geomagnetica, the El.magnetic Low Frequence waves(ELF), the cosmic rays(GCR),etc. .
Why Piccardi for his tests chose the colloidal solutions? because theseones owned the characteristic to be: heterogeneous structures and out
equilibrium (that is not stable) where very little
energies could unbalance already precarious
equilibriums inducing variations with evident effects.
He preferred also to use colloidal solutions originated from inorganic substances, although recognized that the colloidis of the living organisms
were more sensitive in comparison to those inorganic but contemporarily he also considered their
peculiar ability to actively react to the external
input to safeguard his biological equilibrium.
The microbiological test individualized then by
primo '900 appurando in base a dati epidemiologici, che alcune epidemie seguivano un andamento ciclico del tutto analogo a quello dell'attività solare espressa coi Numeri di Wolf. Malattie
infettive come la difterite, la peste, la meningite
cerebrospinale, il tifo, il vaiolo ed altre ancora,
avevano l' acme epidemico in corrispondenza di
quello dell'attività solare che avrebbe agito da
fattore di vero e proprio eccitamento biologico .
Solo nel 1965 però, un anno dopo la sua morte
cioè, i suoi studi furono riconosciuti di considerevole valore scientifico da una Commissione allestita dall'Accademia delle Scienze dell'URSS. Piccardi qualche anno dopo, avrebbe rafforzato le
geniali ipotesi del ricercatore russo con i suoi dati
sperimentali.
Nel 1951, in una generale fase di stallo arenata
in aride ipotesi, Piccardi ruppe gli indugi e decise
di passare ad una verifica sperimentale ricorrendo a test colloidali da lui ideati.
Mise a punto cioè un sistema rivelatore semplice
ma sufficientemente sensibile da raccogliere segnali provenienti da variabili non tradizionali (o
spaziali) come l’Att.Solare, l’Att. Geomagnetica,
le onde el.magnetiche di bassa frequenza (ELF), i
raggi cosmici (GCR),etc. .
Ma perché Piccardi per i suoi test scelse soluzioni
colloidali?
Perché queste erano in possesso delle caratteristica d’essere: strutture eterogenee e fuori equilibrio (cioè non stabili) dove piccolissime energie
potevano sbilanciare equilibri già precari, inducendo variazioni con effetti evidenti .
Egli preferì inoltre di usare soluzioni colloidali originate da sostanze inorganiche, pur riconoscendo che i colloidi degli organismi viventi fossero
più sensibili rispetto a quelli inorganici, ma contemporaneamente considerò anche la loro peculiare capacità di reagire attivamente agli stimoli
esterni per tentare di salvaguardare il proprio
equilibrio biologico.
Il test microbiologico individuato poi dall’A. pareva però, essere un substrato adatto allo scopo di
individuare con effetto rivelatore l’influenza di fenomeni esterni alla biosfera considerati da Piccardi e ciò in quanto substrato che similmente ad
un substrato colloidale avrebbe potuto verosimilmente essere dotato di un potere di auto
compensazione nullo o pressoché tale. Deduzione
che fu poi confermata dalla capacità dimostrata
dal test di avere la sensibilità sufficiente ad evidenziare risposte registrabili alle variazioni nel
tempo di vari parametri fisici esterni, considerati
per palesare una correlazione significativa della
variazioni di essi con quelle del test medesimo.
23
the A. seemed however, to be a proper substratum for the purpose to individualize with revealing effect the influence of external phenomenons
to the biosphere considered by Piccardi and this
as substratum that likewise to a colloidal substratum, it could have had probably a power of
auto compensation void or nearly void. Deduction that was confirmed then through the ability
shown by the test to have the enough sensibility
to underline answers shown in the variations
during the time, of various external physical parameters considered to reveal a significant correlation of the variations of them with those ones
of the same test CSD. This, through many years
of experimental investigations (1970-1991) and
numerous data, derived from over 4 millions of
bacterial colonies.
Piccardi had wished the individualization of a revealing biological test and this biological test individualized by the A. it could have realized his
wishful hopping.
In the 5th international congress of bioclimatology of Montreux in September 1969, Piccardi
textually said < I cannot hope to solve this phenomenology just but I want to hope that what
has now said can interest those people that devote him to the sciences of the life. It is evident
that the sensitive systems and the living organisms, can show above all us what of depth it exists in the universe and to show better him to us
of the tools of physics, always tightly selective
and therefore incapable to warn a general situation - He concluded - The word will be once
more to the study of the fluctuating phenomena
and the sciences of the life>.
The A. started to give his contribution, after Piccardi and Tchijewsky, from the end of the years
'60. During a search about the characteristics of
external air bacteria, he noted that among all the
colonies of the microorganisms, some had the
characteristic to show one or more diversified
sectors in comparison to the remaining structure
of the same colony.
He think to indicate these colonies more shortly
with the initial CSDs. The A. operated for many
months before to hear about Piccardi’s serarches
and had the fortune to met him personally, at
the end of 1970.
Piccardi informed him about his studies on the
fluctuating phenomenons and on the base of
these ones he exhorted the young A. to continuing with his search for a prolonged time to sift
well its validity. After the preliminary searches
1967-69, the A. continued systematically his experimental study about CSD of external air bacteria from 1970 till 1983 and he improved his
simo. Ciò, attraverso molti anni di indagini sperimentali (1970-1991) e numerosissimi dati, riguardanti oltre 4 milioni di colonie batteriche.
Piccardi aveva auspicato l’individuazione di un
test biologico rivelatore e questo test biologico
individuato dall’A. potrebbe averne esaudito il
desiderio.
Al 5° congresso internazionale di bioclimatologia
in Montreux, nel settembre 1969, Piccardi disse
testualmente: << Non posso sperare di venire a
capo di questa fenomenologia appena intravista
ma io voglio sperare che ciò che ho detto ora
possa interessare coloro che si dedicano alle
scienze della vita. E’ evidente che i sistemi sensibili e soprattutto gli organismi viventi, possono
mostrarci ciò che di profondo esiste nell’universo
e mostrarcelo meglio degli strumenti di fisica,
sempre strettamente selettivi e perciò incapaci di
avvertire una situazione generale - e concluse la parola sarà ancora una volta allo studio dei fenomeni fluttuanti ed alle scienze della vita>>.
Accanto a quello di Piccardi e di Tchijewsky l’ A.
cominciò a dare il suo contributo dalla fine degli
anni ’60.
Durante una sua ricerca, infatti, sulle caratteristiche dei germi diffusi nell'aria esterna, aveva notato a latere che fra tutte le colonie dei microrganismi, alcune avevano la caratteristica di presentare uno o più settori differenziati rispetto alla
compagine della colonia stessa.
Tali colonie ritenne di indicarle più brevemente
con le iniziali CSD. l’ A. operò per mesi e mesi
senza sapere delle ricerche di Piccardi che solo
alla fine del 1970 ebbe la fortuna di conoscere.
Nell’incontro, Piccardi gli riferì sugli studi da lui
fatti sui fenomeni fluttuanti e sulla base di questi
esortò l’allora giovane A. perché continuasse a
seguitare la ricerca per un tempo prolungato fino
a vagliarne bene la fondatezza. Così dalle ricerche preliminari fatte prima del 1970, l’A. continuò lo studio sistematico che perfezionò nel
1984, utilizzando colture di laboratorio di ceppi di
S.Aureus; questi infatti avevano dato nello studio
dell’aria esterna una maggiore frequenza delle
CSD.
Dal 1984 al 1991, nonostante che si operasse in
ambiente confinato, si ottennero curve di frequenza delle CSD in tutto sovrapponibili a quella
ottenuta dai batteri dell’aria esterna. Complessivamente dal 1970 al’91, furono controllate oltre
4 milioni di colonie microbiche. Successivamente
i dati raccolti furono messi in correlazione con le
energie esterne alla biosfera, e furono sottoposti
ad un più particolare studio statistico da parte di
fisici invitati a collaborare; e qui si ricorderanno il
24
search in 1984 but using the S.Aureus strains
because these bacteria showed a greater frequency of the CSDs during the 1970-83.
From 1984 to 1991, the S. Aureus strains had
curves of CSDs frequency at all similar to these
ones checked for the external air bacteria despite
that these S.Aureus strains culture were always
in laboratory room. Complessively it was checked
over 4 millions microbial colonies from 1970 to
1991.
Subsequently the collected data had put in correlation with the external energies from the biosphere, and were submitted to a more particular
statistic study derived from collaboration of other
researchers; and here it has to remember the
Belgian M. De Meyer of the Astronomic observatory of Liegi (1984), the italian G. Villoresi of the
Univ. La Sapienza of Roma(1996), the Hungarian
J.' O'rmenyij, of the institute Meteorology of Budapest (2000), the american F. Halberg of the
university of Minneapolis of the Minnesota
(2002), the ukrainian B. Vladimirskji and the
russian A. A. Konradov, university teachers, the
first executive of the Astrophysical observatory
of Crimea and the second of the institute of
Physics and Biochemistry of Pushchino (Mosca)
as well as member of the academy of the Sciences of USSR before and of Russia successively
(2005).
These collaborations confirmed the principal intuitions had from Faraone and in previously
clearly brought in the publications of 1971 and
1974, where he hypothesized that more external
factors would have been able to condition the
frequency of the CSDs, as the ELF, the G Cosmic
Rays, the Solar Activity and Geomagnetic Activity.
From the results had picked up since 1970 to
1991, it appeared clear that CSDs frequency is
essentially a fluctuating phenomenon with typical
periodicity occurring every eleven years; and his
correlation statistically resulted significant with
the solar activity (considering the variations of
the sunspots and the solar flow in the range of
2800 MHz), with the ELF [so that electromagnetic of low frequency, 3 and 10 Hz] as well as
that with the geomagnetic activity (you see
storms e.m.).
The A. had the more prolonged collaboration with
Halberg, realized bright biostatistical studies on
the correlation with the solar and geomagnetic
activity. Vladimirsky and Konradov were the
more recent collaborators (2005), it was ascertained statistically that it was the most creditable
to be prominent the influence of the waves
el.magnetiche of low frequency, influenced by
belga M. De Meyer dell'Osservatorio Astronomico
di Liegi (1984), l'italiano G.Villoresi dell' Univ. La
Sapienza di Roma (1996), l'ungherese J.
'O'rmenyij, dell'Istituto Meteorologia di Budapest
(2000), lo statunitense F. Halberg dell'Università
di Minneapolis del Minnesota (2002), l'ucraino B.
Vladimirskji e il russo A. A. Konradov, docenti universitari, il primo dirigente dell'Osservatorio Astrofisico di Crimea e il secondo dell'Istituto di Fisica e Biochimica di Pushchino (Mosca) nonchè
membro dell'Accademia delle Scienze dell'URSS
prima e della Russia successivamente( 2005) .
Da tali collaborazioni risultarono confermate le
principali intuizioni avute dall’ A., e in precedenza
chiaramente riportate in pubblicazioni del 1971 e
del 1974, dove si era ipotizzato che più fattori
esterni avrebbero potuto condizionare la frequenza delle CSD, quali: le ELF, i GCR, l’ Attiv.Solare e l’ Attività Geomagnetica.
Dai risultati raccolti dal 1970 al 1991, apparve
chiaro di trattarsi di un fenomeno fluttuante con
periodicità di tipo undecennale; e risultarono statisticamente significative, la correlazione con l'attività solare (considerando le variazioni delle macchie solari e del flusso solare nel range di
2800 MHz), quella con le onde ELF [onde elettromagnetiche di bassa frequenza, 3 e
10 Hz] nonché quella con l'attività geomagnetica
(vedi tempeste e.m.). Sulla correlazione con
l’attiv.geomagnetica realizzò brillanti studi biostatistici Halberg col quale l’A. ebbe la più prolungata collaborazione.
Vladimirsky e Konradov per citare i collaboratori
fisici più recenti (2005), cogli elaborati statistici
appurarono come fosse la più accreditabile ad
essere
preminente
l’influenza
delle
onde
el.magnetiche di bassa frequenza, influenzate
dall’attività solare medesima.
Ciò, considerando anche i raggi cosmici (come
flusso neutronico) data la correlazione significativa esistente fra di essi e l’attività solare
(corr.negativa) e di quest’ultima con la freq. delle CSD(corr.positiva).
Essi aggiunsero pure come le CSD [1970/79]
fossero state più frequenti nella fase negativa del
campo magnetico interplanetario rispetto alla sua
fase positiva e in questa correlazione accostarono il test CSD a quello F, dei test colloidali di
Piccardi.
Nei risultati sulle CSD rispetto a quelli avuti dai
test di Piccardi di diverso si nota che in quelli di
Piccardi le correlazioni con l’attività solare [D ed
F] e con quella geomagnetica [F] sono positive
mentre per le CSD sono negative; corrispondono
però i minimi di primavera e d’autunno [in D] e il
massimo d’inverno [in F]; inoltre le curve di fre-
25
the same solar activity confirming the previous
researches of the A. with ‘O’rmenji. It was ascertained also that the CSDs [9the70/79] were
more frequent in the negative phase of the interplanetary magnetic field in comparison to the
positive phase and in this correlation they considered approachable the CSD test to the F of
colloidal tests of Piccardi. It was considered also
a significant correlation with cosmic rays (as the
neutronic flux), deducible indirectly from the significant correlations between the solar activity
and cosmic rays (negative corr.), and the solar
activity with CSDs freq. (positive corr.).
quenza del test CSD appaiono meno disturbate
da presumibili interferenze.
Sostanzialmente l’A. ha confermato quanto detto
da Piccardi, e cioè che segnali esterni da variabili
non tradizionali, possono indurre effetti tangibili
su substrati sia che essi siano soluzioni colloidali
sia che essi siano microrganismi, la cellula dei
quali, detto per inciso, possiede sostanze allo
stato colloidale.
The A. remarked also several differences between CSD fr. and colloidal Piccardi’s test , (see
the Table.).:
- the correlation of solar activity (Wolf’s Number)
was positive wih D and especially. with F
of.colloidal test whereas it was negative with
CSD freq. test.
-.the correlation of geomagnetic activity was
positive with F test whereas it was.,.negative in
CSD freq. test.
- during the year medially the minima data in
spring and autumn were evident in..CSD fr. test
.but also in D test.
- the maxima data on winter for F test were present also for CSD fr. test.
- the curves of the CSD fr..test appear less disturbed by resumable interferences.
Substantially the A. has confirmed what Piccardi
noted in his test :
- that external signals from non traditional variables, can induce tangible effects on.substrata
of colloidal solutions but the A. noted that this
effects are also in the bacteria substrata where
it’s to consider that the sustances are in the
colloidal state.
- that the variations during the time of colloidal
data and of CSD fr data are together
to.consider at all
typical
of
fluctuanting
phenomena.
Table of Colloidal-Piccardi's tests in the detailed confronting of CSD test.
Colloidal
tests of
Piccardi:
Test D
Test F
Test P
Positive correlationSlightly positive cor- Positive corr. with solar act., in
Secolar Vawith solar activity relation with solar Florence and negative (2) in
riation:
(1).
activity (1).
Tubinghen and Jungfrau.
Minimum on the
Minimum in
summer.
Variations with terrestrial, soAnnual Va- March and August
Maximum on the
lar and cosmic radio electr.
riation:
but less in August
winter (4)
emissions.
(3).
ShortIncreasing (5) with
Increasing with
sensibility to the artificial
period Vasolar eruptions and
cosmic radiations.
electr.magnetic waves.
riation :
magnetic storms.
26
-
tests D and F: in CSD test on the contrary, this correlation is negative.
test P: similarly, in CSD test , this correlation is negative.
test D: similarly, in CSD test , a less evident minimum is generally in September, during the
year.
test F: similarly, in CSD test , the most evident maximum is generally in November, during the
year
test F: in CSD test on the contrary, during magnetic storms the data are lower.
The colloidal state is therefore a common denominator for the substrata used from the two
researchers and in such sense I would consider
expecially the water, whose omnipresence in our
habitat shows an absolute protagonism not only
as medium but also as governing body in regarding of external signal / substratum receptor.
Concluding, Tchijewsky ingeniously picked up
numerous epidemiological data, noticing that the
epidemic course of the.infectious desease from
him studied, it followed a cyclical rhythm typical
of the solar activity to which tightly it seems
connected. Piccardi experimentally realized a colloidal test that underlined the same solar rhythm
for the data emerged by the colloidal precipitations. The A. experimentally individualized a detector of biological type in correlation with the
solar cycle, a detector that would represent also,
in according with the literature, the presence of a
possible mutation and therefore a possible involvement of the DNA to contributing to favour a
selection in the bacterial population (relationship
external signal / adaptation-biological substratum).
The biological substratum adapts him through
the selection, for certain environment conditions
or in a relationship of full compatibility that
means existence or in a relationship of incompatibility that means more rapid extinction. Such
relationship is absolutely inevitable. In a simple
microorganism the mechanism that preserves his
kind not stung on the self-biological compensation but on a selection of the population and this
pro-someone that responds fine to environmental difficulties and in damage of many that
dies soon.
The rule that seems to be valid for the bacterias
is: to a fast extinction / a fast reproduction, In
more complex beings the mechanism of adaptation of the kind requires less the hecatomb of the
single ones, it tends more on an individual autocompensation mechanism (that is very more
valid as anymore the creature is complex and the
kind is evolved).
Concluding the CSDs search can valorize more
still the work of Tchijewsky, because the presence of induced modifications in the bacterias
and revealed by the presence of the CSDs, could
represent the logical premise of rising up of an
Ricapitolando, Tchijewsky raccolse numerosi dati
epidemiologici, notando che l'andamento epidemico delle mal. infettive da lui studiate seguivano
un ritmo ciclico tipico dell'attività solare alla quale lo riteneva strettamente collegato.
Piccardi ideò sperimentalmente un sistema rivelatore chimicofisico che evidenziò il medesimo
ritmo solare per i dati emersi dalle precipitazioni
colloidali da lui messe a punto. L’ A. ha poi ritenuto di avere individuato sperimentalmente, in
concordanza col ciclo solare, un mezzo rivelatore
di tipo biologico che rappresenterebbe pure, secondo la letteratura, la presenza d’una possibile
mutazione e quindi un possibile coinvolgimento
del DNA nel contribuire nel favorire una selezione
nella popolazione batterica (rapporto segnale esterno / adattamento-substrato biologico).
Attraverso la selezione, il substrato biologico si
adatta a certe condizioni ambientali o in un rapporto di piena compatibilità che significa esistenza oppure in un rapporto d’incompatibilità che significa estinzione più o meno rapida. Tale rapporto è assolutamente inevitabile. In un semplice
microrganismo il meccanismo che preserva la
specie non punta sulla autocompensazione ma su
una selezione della popolazione e ciò a favore dei
pochi che si adattano e/o resistono all’ambiente
e a discapito dei molti che non facendolo, si estinguono in tempi relativamente brevi. La regola che pare valere per i batteri è: a veloce estinzione, veloce riproduzione.
In esseri più complessi invece il meccanismo di
adattamento
della
specie
richiede
meno
l’ecatombe dei singoli, e punta di più su un meccanismo individuale di auto-compensazione che é
tanto più valido quanto più l’individuo é complesso e la specie è evoluta ).
Concludendo lo studio fatto sulle CSD può valorizzare ancor di più l'opera di Tchijewsky, nel
senso che la presenza di modificazioni indotte nei
batteri e rivelate dalla presenza delle CSD, potrebbero rappresentare la premessa logica
dell'insorgere di un'onda epidemica. Infatti l'attività solare, restando nell'ottica del russo, agirebbe da forza biostimolante che agendo su una popolazione batterica già arricchita da individualità
cellulari modificate da svariati input esterni, potrebbe esserne agevolata nell’ innescare un successivo rash epidemico.
27
epidemic wave.
The solar activity, staying in the optics of Tchijewsky, it would be the biostimolating strength
on a bacterial population already enriched by cellular individuality modified by several external
inputs; and this population could be helped to
give a following epidemic rash.
A tal proposito fra gli input esterni si sottolinea
ad es., il flusso neutronico il cui acme figura in
alternanza temporale con l’acme dell’attività solare [rilevamenti russi e statunitensi], e nel contempo si accompagna all’ aumento di frequenza
delle CSD [ 1970–1991].
Degli input esterni, questo potrebbe essere uno
e dei fattori che sarebbe meglio da inquadrare, per
It is underlined in this sense between the exter- i l’influenza che può avere sulle CSD.
nal inputs, the neutronic flow of cosmic rays,
Concludendo i risultati rilevati dall’ A. , gli studi
whose peak shows up in temporal alternation
di Piccardi e di Tchijewsky prima citati , si
with the peak of the solar activity [Russian and
combinerebbero tra loro come tessere di un uniAmerican surveys] and at the same time there is
co mosaico, dandone un avvincente senso coman increasing of the CSDs frequency [1970piuto.
1991] in significant correlation negative with solar activity that is in significant correlation negaInfine s’ intende rimarcare come i fattori esterni
tive with neutronic flux.
condizionanti le CSD, non siano limitati al sole
ma possano essere diversi, contemporanei e fra
How much may influence the neutronic flux the
loro interconnessi. Combinando la loro influenza
CSDs frequency compared with the other exterperò, finiscono per complicare la possibilità d’ innal inputs?
dividuare quello dominante.
Concluding the results noticed by the A., the
Forse, anche qui si potrebbe parlare di una
searches of Piccardi and Tchijewsky before cited
condizione fluttuante dei vari fattori esterni che
may be combined together as plots of a same
veda ora in uno ora in un altro , quello premosaic and give a charming completed meaning
minente come influenza per un determinato peof this.
riodo.
The A. intends to observe as the external factors
Infine, le metodiche e i materiali utilizzati per reinfluencing the CSDs, are not limited to the sun
alizzare il test CSD sono assi meno impegnativi
but can be different, contemporary and among
nelle manualità, apparendo peraltro anche meno
them interconnected. Combining their influence,
suscettibili di errore di quelli serviti per realizzare
however they complicate the possibility d ' to ini sensibilissimi test colloidali di Piccardi.
dividualize the dominant factor, if this there is .
It could be said perhaps also of a fluctuating
condition of the various external factors where a
Remarking :
prominent factor may influence only for a determined period.
( 1 ) I fenomeni biologici fluttuanti, possono preFinally, the method and the materials used for
sentare dati che siano suscettibili di avere una
realizing the CSD test, are less arduous for the
idonea verifica sperimentale che consenta di apsimple laboratory-operations and are less susprezzarne una validità attraverso la constatazioceptible of errors than the metods and materials
ne dei seguenti elementi fondamentali.? L’A. è di
utilized in realizing the sensitive colloidal tests of
questo
parere,
purchè
si
rispettiPiccardi especially as a work amount and refined
no.le.seguenti.condizioni.particolari.:
technique of the execution, together considered.
a)
che i fenomeni biologici allo studio presentino una periodicità che si rinnovi ritmicamenTherefore the A. advices the techniques realized
te nel tempo (bioritmi) e che nel confronto con
in the 2th period of CSD research (1984-91), as
fenomeni fisici cosmici che abbiano notoriamente
a good mean to have the CSD results through
analoga caratteristica (vedi l'attività solare), tale
more simplicity than the means utilized in the
periodicità possa permettere d'individuare l'esi1th period (1970-83) of his research but also
stenza di una correlazione significativa dal punto
utilizing single strains of S. Aureus rather than
di vista.statistico.
an air bacteria miscellany, avoiding also a further
operation as the external air samplings of microb) che la verifica incrociata di tutte le correlaorganisms.
zioni significative possibili scaturite dal confronto
fra il fenomeno biologico allo studio e svariati alRemarking :
tri parametri fisici del cosmo, fornisca un quadro
generale d'assieme di assoluta coerenza inter(1) Are the fluctuating phenomena data susceppretativa quale conferma della validità della ritible to have a suitable experimental trial to apcerca
pre
28
preciate its validity through some fundamental
characteristics.:?
Yes, on the understanding that :
a) the biological phenomena studied are able
to show a periodicity that rhythmically renew
himself on the time (biorhythms) and in comparison with cosmic physical phenomena with
analogous characteristic (i.e., the solar activity),
this periodicity can allow to individualize statistical.significant.correlations.
b)
the cross-trial of every significant correlations through the comparison between the biological phenomena studied and other physical
parameters of the cosmos, all together may give
a general panorama of absolute interpretative
coherence in confirmation of the validity of the
research.
c) the observation is absolutely to effect for
congruous time periods(long-term observing)
comparable to those effected by the authors
cited in this lecture.
Therefore the A. opinion is that these trials are
right only in a general panorama of interpretative
coherence that had considered several physical
parameters(as much as possible) in reciprocal
comparison with CSD frequency.
The trials realized in the modalities said before,
are at all coherently into the Galilean concept of
reproducibility also if it’s in referring of the semipermanent phenomena as the fluctuating phenomena are.
(2) The CSD (colonies with sector or sectors differentiated) are counted, independently of number of sectors, as percentage of total counted
number of colonies increased in Petri dishes, after each sampling collected day by day.
(3) References:
See please articles of A., on CSD and their references in : Cifa News 30-40:
http://www.cifa-icef.org/news_30_ita.html >, §
Cifa News (the news are updated on September
2007).
c) che l'osservazione venga effettuata per periodi di tempo assolutamente congrui (osservazioni
a lungo termine) paragonabili a quelli attuati dagli autori citati nella mia relazione.
L’A. è del parere che ciò sia verosimile in un
quadro generale di possibile coerenza interpretativa.
Tutto ciò, non potrebbe non ricadere dunque nel
concetto galileiano di riproducibilità dei fenomeni
detti semipermanenti come sono i fenomeni fluttuanti.
(2) Le colonie a settore differenziato o CSD sono
enumerate, indipendentemente dal numero dei
settori, come percentuale del numero totale delle
colonie cresciute sulle piastre colturali Petri, dopo
ogni campionamento giornaliero.
(3) References : Vedere gli articoli dell’ A. sulle CSD e i loro riferimenti bibliografici riportati
nelle varie pubblicazioni dei CIFA News, numeri
30-40,
al
sito
web:
http://www.cifaicef.org/news_30_ita.html, paragrafo CIFA
News (tali pubblic. sono aggiornate fino al Settembre 2007). Grazie
29
The work of Davydov and scientific evidence
of solitons in alive systems
by LARISSA BRIZHIK
(Bogolyubov Institute for Theoretical Physics,
Metrologichna Str., 14-b, 03680 Kyiv, Ukraine;
International Institute of Biophysics, Neuss,
Germany - e-mail [email protected])
This lecture is an introduction to the theory of Davydov’s solitons in biological systems. The concept
of molecular solitons has been initially suggested by an outstanding Soviet scientist Alexander Davydov in 1980s to explain the mechanism for the energy storage and transfer in biological macromolecules [1]. Davydov's soliton is a self-trapped localised state of an electron or AMID-I excitation in a
one-dimensional polypeptide molecular chain. Such soliton is a bound state of a quasiparticle and local
chain deformation. It is formed in the result of the quasiparticle self-trapping by the local deformation
created by a particle itself. The general properties of solitons as stable localized nonlinear solitary
waves are discussed. Examples of solitons in physical systems (fibre optic communications, plasma,
atmosphere, hydrodynamic tsunamis, crystal lattices, etc) are given to visualize these nonlinear objects and to give the clue about their very specific properties. An overview of the applications of the
concept of solitons in biological systems is suggested. Among these applications there are molecular
solitons and electrosolitons in alpha-helical proteins, nerve propagation in the form of solitons, solitons
in DNA, soliton mechanism of muscle contraction, etc.
Special accent is given to the molecular solitons that provide the energy and charge transport during
the metabolic processes. Such soliton states are formed, for instance, in alpha-helical proteins that
participate in the photosynthesis, in such macromolocules like citochrom с-oxidase in the redox chain
in the respiration processes in mitochondria, etc. For the simplicity a one-dimensional molecular chain
is considered and it is shown that the account of the interaction of a quasiparticle (it can be an electron or AMID-I excitation of the peptide group, excited by the quantum of energy that is released in
the hydrolythis of the adenosine-triphosphate into the adenosine-diphosphate) with the local deformation of the polypeptide chain results in the self-trapping of a quasiparticle in a localized soliton-like
state, known as Davydov's soliton. Such soliton is exceptionally stable, it propagates along the macromolecule with the constant velocity together with the local deformation of the chain almost without
the energy dissipation [1-3].
The important role of the helical symmetry of macromolecules in the formation, stability and dynamical properties of solitons [4] is elucidated. In particular, it is shown that the energy spectrum of quasiparticles in an alpha-helical macromolecule, stabilized by three polypeptide chains of hydrogen bonds,
contains three energy bands. The upper band is a nondegenerate and has the minimum in the centre
of the Brillouin zone. The lower band in the energy spectrum is degenerate into two bands which have
minima at nonzero values of wave-vectors, symmetrically shifted with respect to the centre of the Brillouin zone, by the values
± k0 = ±
3 3L
. Here J and L are, respectively, intra- and inter-chain
(18J + L)a
exchange energies, a is the hydrogen bond length. The corresponding system of nonlinear equations
admits several types of soliton solutions, among which there is the hybrid soliton solution which is
formed by the hybridization of the quasiparticle states from the two lowest degenerate energy bands.
It is shown that this soliton has the lowest energy and posseses an inner structure with the manyhump envelope.
The amplitude of this envelope, Pj(n),distributed on individual spines, is shown in Fig.1. This soliton
breaks spontaneously the local translational and helical symmetries of the macromolecule.
H
LH
L
30
Fig.1
Probability distributions of a
hybrid soliton, Pj(n), in the
three individual spines of alpha-helix,
j=1,2,3
(three
lower curves). Upper curve
corresponds to the total
probability, Ptot(n)= P1(n)+
P2(n)+ P3(n).
Pj n , Pt o t n
0.5
0.4
0.3
0.2
0.1
n
25
50
75
100
The total probability of the excitation on the j-th spine is given by the expression
⎤
πk 0
1⎡
Pj (t ) = ∑ Pj ,n (t ) = ⎢1 −
cos(2k 0Vt − 2πj / 3)⎥ ,
(1)
3 ⎣ κ sinh(πk 0 / κ )
n
⎦
9χ 2
is the localisation parameter of a hybrid soliton, χ is the electron-phonon
where κ =
wa(18 J + L)
coupling, w is the elasticity coefficient, that is proportional to the elasticity of a hydrogen bond, and V
is the soliton velocity. We see from (1) that the probability of the excitation on a given spine is an oscillatory function of time with the period of oscillations, determined by the soliton velocity V:
Th =
π
k 0V
.
(2)
In particular, for the soliton velocity equal to 3/8 of the sound velocity [2] for an AMID-I excitation in
alpha-helix (J=1.55 10-22 Jole, L=2.46 10-22 Jole, k0a=0.422), we obtain the value Th=2 10-12 s. Altogether, these results explain a soliton structure, interspine oscillations and their frequency, observed
numerically by A.C. Scott [2].
These helical oscillations get mixed up with the oscillations that arise from the influence of the lattice
discreetness on the soliton dynamics which leads to the appearance of the periodic Peierls-Nabarro potential. The period of these longitudinal oscillations is also determined by the soliton velocity [5]:
Tl =
which is one order of magnitude smaller than Th.
a
,
V
(3)
The oscillating character of the propagation of solitons and other specific properties of solitons can be
responsible for some peculiar phenomena in the biological systems, which linear theories can not explain. In particular, according to the analytical and numerical study [6], the influence of the external
electromagnetic radiation on the dynamics of electrosolitons (i.e., solitons, that carry an electron
charge), has a nonthermal resonant character with several characteristic frequencies. Such influence is
characterized by two characteristic frequencies of electromagnetic fields
respectively, and is qualitatively different. Here
ω0 =
2 μVa
π
and
ωdis =
χ4
hJw2
,
μ and Va are soliton width and velocity of the sound
in the polypeptide chain. At low frequencies of the radiation, electrosoliton absorbing the energy from
the field, generates the acoustic waves. This process is most intensive in the fields of frequencies
ω ≈ 1.3ω0 , determined by the characteristic time scale of the retardation effects, which is determined,
in its turn, as the ratio of the soliton width to the sound velocity. The generation of acoustic waves in
polypeptide chain can result not only in the local heating of the system, but also such sound waves
can propagate along the alpha-helix as in the channel carrying some additional information. Moreover,
the generation of the sound can change qualitatively some functioning processes connected with conformal states of macromolecules or their fragments, since electromagnetic radiation of the corresponding frequencies causes the oscillations of electrosolitons including the oscillations of the chain distortion.
31
When the frequency of electromagnetic radiation corresponds to the energy splitting of the electrosoliton level from the energy band bottom, the quantum transition of the electrosoliton into a delocalized
band state occurs. Hence, the electromagnetic radiation of the frequencies ω ωdis can destroy an
electrosoliton completely, making the coherent charge transport in the system far less effective, if
possible. More precisely, the charge transport in biological systems is provided by bisolitons which are
bond states of two electrosolitons with opposite spins [7], and one can expect the spectrum of bisoliton interaction with electromagnetic radiation to be reacher than those of a single electrosoliton.
Due to the oscillating character of propagation, electrosolitons, according to Maxwell equations, emit
electromagnetic radiation [8]:
eV02
E rad (r ) =
2aε 0 c 2 r 3
∞
4nq n
sin(nωt )r × (r × l )
∑
2n
n =1 1 + q
(4)
eV02
B rad (r ) = −
2aε 0 c 2 r 2
∞
4nq n
sin(nωt )l × r
∑
2n
n =1 1 + q
(5)
where the frequency of the main harmonic of oscillations,
ω=
2πV0
a
(6)
is determined by the average soliton velocity, V0. According to the numerical estimates, it is of the order V0 ∼ 1.5×103 m/s, which gives the following estimate for the main harmonic frequency: ν=ω/2π ∼
1012 s-1. This radiation constitutes the component of the endogenous electromagnetic field with characteristic resonant frequencies, which, according to (6), depend on the soliton velocity, which, in its turn,
is determined by the metabolic activity of the system. The superposition of the longitudinal and helical
oscillations of the electrosoliton results in a more complex spectral structure of this field with components of various polarization properties and radiation pattern. Namely, the longitudinal oscillations
cause plane polarized radiation which can be described as the radiation of some effective dipoles, oriented along the helix axis [4]. Meanwhile, the component of the radiation due to the helical oscillations, has circular polarization. Alltogether, this radiation can be responsible for the biocommunication
in living systems (see, e.g., [9,10]). Exchange by this radiation leads to synchronization of soliton motion [8]. Moreover, at different velocities solitons generate EMR of different noncommensurate frequencies and the total intensity of the EMR is proportional to the number of solitons, N, while in the
case of their synchronized motion and emision it is proportional to N2. The soliton model predicts the
dependence of the intensity of bioelectromagnetic field on the functional state of a cell: the total radiation depends on the concentration of solitons which is determined by the metabolic activity of a system. The selfregulation of solitons via their radiation can be stimulated by the external weakradiation
of the corresponding frequencies. Indeed, some results of microwave resonance therapy indicate such
weakirradiation stimulates the internal immune and self-regulating systems [11].
The life-time of solitons is determined by the relaxation processes in proteins and is inverse proportional to the probability of photon emission due to transition of a protein from an excited hybrid soliton
state into the ground one. The radiative life-time of a hybrid soliton, τ h , related to this transition, is
given by the expression.
τh =
Here
τ0
4κaτ 0
⎡π (k 0 a + 2π / 6) ⎤
cosh 2 ⎢
2
2
⎥.
2κa
3π sin ϑ
⎣
⎦
is a lifetime of an isolated excitation of a peptide group,
ϑ
(7)
is an angle between the orientation
of the dipole momentum of an excitation and helix axes. For the parameters of an AMID-I excitation in
o
alpha-helix κa =0.176, ϑ = 30 we get τ h / τ 0 = 5 .8 ⋅ 10 9 . Therefore, the radiation lifetime of a hybrid
soliton in a helical structure is much bigger than the lifetime of an AMID-I soliton, τ s , in a three-spine
model with zero helicity [12]: τ h / τ s = 2 ⋅ 10 3 .
32
Therefore, the helicity of a protein significantly increases the radiative life-time of AMID excitations in
proteins. This conclusion agrees with recent experiments of Austin et al. [10], which show that the
life-time of an excitation in myoglobin, that is essentially alpha-helical protein, is much bigger than in
isolated aminoacid such as L-alanine. According to [10], such an excitation in myoglobin has necessarily the nonlinear nature. In our opinion, this nonlinear nature can originate from the electronphonon interaction and anharmonicity of proteins, leading to the self-trapping of excitations and electrons in soliton-like states and in the significant increase of the life-time. Moreover, such solitons provide the complex endogenous electromagnetic radiation of characteristic frequencies with the resulting
synchronization of charge transport processes, which, in its turn, provides the coherence of the guiding electromagnetic field and self-regulation of metabolism [9-11]. The electromagnetic radiation by
solitons (4)-(5) by its properties coincides with the radiation from coherent dipoles, suggested by H.
Froehlich [14]. The radiative decay of solitons contributes to the weak photon emission from biosystems, measured experimentally [15].
[1]
[2]
[3]
[4]
[5]
[6]
[7]
[8]
[9]
A.S. Davydov. ). Solitons in Molecular Systems, Dordrecht, Reidel, 1985.
A.C. Scott, Phys.Rev. A 26 (1982) 578.
L.S. Brizhik. Ukr. J. Phys., 48 (2003) 611-622.
L.S. Brizhik, A.A. Eremko, B. Piette W.J. Zakrzewski, Phys. Rev. E 70 (2004) 031914.
L. Brizhik, L. Cruzeiro-Hansson, A. Eremko, Yu. Olkhovska, Phys. Rev. B 61 (2000) 1129.
L.Brizhik, L. Cruzeiro-Hansson, A. Eremko. J. Biol. Physics, 24 (1998) 19-39.
L.S. Brizhik, A.S. Davydov, Sov. J. Low Temp. Phys., 10 (1984)748-753
L.S. Brizhik, A.A. Eremko, Electromagnetic Biology and Medicine 22 (2003) 31.
M.-W. Ho, F.-A. Popp, U.Warnke. Bioelectrodynamics and Biocommunication. World Scientific, Singapore, 1994.
[10] J. Pokorny, T.-M. Wu. Biophysical Aspects of Coherence and Biological Order. Academia, Prague,
1998.
[11] B.P. Grubnik, S.P. Sitko, A.A. Shalimov, Phys.Alive, 6 (1998) 97.
[12] A.S. Davydov, A.A. Eremko, A.I. Sergienko, Ukr. J. Phys. 23 (1978) 983.
[13] A. Xie, L. van der Meer, W. Hoff, R.H. Austin, Phys. Rev. Lett. 84 (2000) 5435.
[14] Froehlich, H.: Coherent Excitations in Active Biological Systems, in Modern Bioelectrochemistry F.
Keyzer , ed. Plenum Press, N.Y., 241-264, 1986.
[15] F.-A. Popp. Frontier Perspective, 11 (2002) 16-28.
33
Osservazioni sulle variazioni bioelettriche nell’uomo
indotte da campi elettromagnetici
in camera amagnetica
(1) Cattedra di Medicina del Mare Università di
Roma “La Sapienza”
(2) Istituto Neurobiologia e Medicina Molecolare
CNR Roma
by V. I. VALENZI (1), S. GRIMALDI (2), GIUSEPPE QUARTIERI (4), G.E. GIGANTE (3), G.
MONACO (1), GRAZIANO MILETO (4)
(3) Dipartimento di Fisica Università di Roma
“La sapienza”
(4) Centro Studio di Biometeorologia Onlus Italia, Omegadati S.r.l.
SOMMARIO
Si riportano alcuni risultati del metodo di misura degli effetti della interazione tra campi elettromagnetici e biosistemi basato sull’ EAV (Elettro-agopuntura di Voll). Questo metodo di misura semplice ed
elementare è stato applicato a sette persone in apparente buona salute, in varie condizioni di esposizioni a campi elettromagnetici utilizzando tra l’altro una camera amagnetica. Si è tentato di elaborare
una correlazione fra livelli di misura, eseguite con una unità di misura di scala, ed gli eventuali effetti
biologici sulla salute (cefalee, gastropatie, alterazione dello stato di attenzione ecc). Si accenna quindi
ad uno studio preliminare di sviluppo del modello matematico di flusso di corrente nella pelle umana
che si profila come base elementare per la elaborazione di un modello matematico più accurato e robusto da sviluppare nel futuro.
INTRODUZIONE
P
rima di procedere con le osservazioni del caso di specie, si coglie l’occasione per fare notare che
l’interesse e la applicabilità in capo aerospaziale degli effetti dei CEM è giustificata dal fatto che i CEM
non si limitano solo a colpire gli uomini sulla crosta terrestre ma anche quelli eventualmente nello spazio atmosferico e cosmico.
La ricerca sugli effetti dei campi elettromagnetici (CEM) sulla salute umana non è ancora pervenuta a
conclusioni univoche come si può peraltro dedurre dalla diversità di limiti di esposizione ai CEM emanati dalle varie Autorità nazionali ed internazionali nel settore (Rif. N° 13, 14, 15, 16, 17, 18, 20). In
particolare viene riconosciuto, accettato, misurato e normato l’effetto termico (tipo forno a microonde)
dei CEM sull’uomo mentre solo da qualche tempo vengono studiati gli effetti non termici dei campi
elettromagnetici. In particolare, lo studio degli effetti di risonanza di ciclotrone degli ioni e, in genere,
di cellule e tessuti biologici è appena iniziato in modo sistematico anche se alcuni risultati basati su
approcci parziali di flusso quantistico e superconduttivo di corrente elettrica nei tessuti biologici interni
e/o superficiali sono stati in parte pubblicati. Mancano comunque ancora evidenze sostanziate e inoppugnabili sulla vastità ed applicabilità dei modelli sviluppati per la interpretazione – eventualmente anche epidemiologica – degli effetti biologici della radiazione elettromagnetica nelle varie gamme di frequenza (ELF, Microonde, RF ecc.). La Relazione Conclusiva Annuale III Anno (maggio 2003-2004) del
Prof. Paolo Bernardi (Rif. N° 15) sul Progetto Nazionale MIUR/CNR-ENEA “Salvaguardia dell’uomo e
dell’ambiente dalle radiazioni elettromagnetiche” fissa un punto essenziale della attuale visione di tutta
al fenomenologia almeno così come è stata analizzata, osservata e studiata con le metodologie classiche di interazione dei CEM con le cellule e i tessuti biologici.
Ovviamente, i limiti di definizione di questa analisi e delle relative misure effettuate sono ben definiti e
netti poiché basate sui S.E.P..
LE OSSERVAZIONI ATTUALI
Tra gli effetti non termici (Rif. N° 20), si è avuto modo di studiare gli effetti dei CEM sulle
funzioni bioelettriche, collegate allo studio Ohmico dei circuiti elettrici corporei misurabili
con uno strumento EAV (Elettro-agopuntura di Voll prodotto dall’Istituto CSM di Udine).
34
Tra i vantaggi del sistema EAV CSM, va annoverato un programma di elaborazione grafica della misura che consente di ridurre il limite della riproducibilità della misura tipico del sistema EAV.
In precedenti comunicazioni (Rif. N° 1-12), era stato osservato come nel corso di numerose sperimentazioni e misure, con strumenti che valutano le funzioni elettriche cutanee e corporee era stata rilevata l’aumento della resistenza elettrica nei circuiti elettrici corporei dei soggetti sottoposti a campi elettromagnetici. In corrispondenza di tale aumento di resistenza elettrica con corrispondente riduzione
delle correnti elettriche si evidenzia, nell’uomo, una riduzione della forza muscolare valutabile con test
chinesiologici, che potrebbe avere anche altri significati fisiopatologici su altri organi e sistemi corporei
ancora non studiati adeguatamente;
Nel corso di una giornata di sperimentazioni presso il CNR di Tor Vergata, abbiamo avuto la possibilità
di misurare le variazioni dei SEP (Skin Electric Parameters) misurate con il metodo EAV con una scala
aspecifica da 0 a 100 che è stata parzialmente misurata in una serie di misurazioni con resistenze test
realizzate da Aldo Aloe del Dipartimento di Fisica della “Sapienza”, dove sono state rilevate le seguenti
corrispondenze tra punti della scala (definite in Unità di Scala: us) e le resistenze elettriche misurate in
Ohm:
Tab. N° 1 Corrispondenza fra Punti di Scala e Resistenze Elettriche
0 us
5 us
24 us
32 us
43 us
49 us
50 us
62 us
corrisponde a
corrisponde a
corrisponde a
corrisponde a
corrisponde a
corrisponde a
corrisponde a
corrisponde a
8,7 milioni di Ohm
1,47 milioni di Ohm (1,47MΩ)
300.000 Ohm (300 KΩ)
200.000 Ohm (200 KΩ)
130.000 Ohm (130 KΩ)
100.000 Ohm (100 KΩ)
95.000 Ohm (95 KΩ)
63.000 Ohm (63 KΩ)
Le misure sono state realizzate in sette persone in apparente buona salute, in varie condizioni di esposizioni a campi elettromagnetici utilizzando tra l’altro una camera amagnetica che ci ha garantito la riduzione dei molteplici fattori di disturbo delle misure in ambienti aperti. Lo studio del grafico ci mostra una notevole sovrapponibilità dei valori medi
dei S.E.P. misurati in laboratorio ed in camera amagnetica, a indicare che, normalmente,
non si rilevano influenze elettromagnetiche in ambiente di vita e di lavoro, in grado di interferire con i S.E.P..
Diversa è la valutazione dei rilievi in presenza di una radiofrequenza, posta a meno di un metro dal
soggetto: i valori medi risultano molto ridotti, dell’ordine di 20-30 U.S. che corrispondono ad una variazione di 50–100 KOhm. Utilizzando vari materiali, alcuni dei quali disponibili sul mercato) abbiamo
osservato un importante recupero dei SEP che si sono riportati intorno a 60 di media con un recupero
importante in tutti i soggetti testati.
Le considerazioni che si possono trarre da queste osservazioni indicano una realistica possibilità di incidere nella regolazione e nella normalizzazione delle funzioni bioelettriche che vengono alterate da
campi elettromagnetici artificiali, come studiato in questo esperimento oltre che da anomalie magnetiche naturali che, benché siano di incerta origine e di difficile misurazione, nell’esperienza clinica e in
ambito agroalimentare, hanno evidenziato una pericolosa capacità di alterare i normali processi chimico-fisici animati ed inanimati come ben mise in luce il prof. Giorgio Piccardi nei suoi studi sui colloidi.
Effetto depressivo di una radiofrequenza sui potenziali cutanei
80
70
Unità Scalari
60
50
rilevamenti in laboratorio
40
rilevamenti in camera amagnetica
rilevamenti in camera amagnetica con radiofrequenza
30
20
10
0
1
2
3
4
5
soggetti testati
6
7
8
9
35
Nonostante ancora oggi molti fenomeni osservati non trovino un razionale scientifico adeguato, non significa che non esistano, anche perché oltre agli studi di Piccardi sull’influenza di segnali deboli sui sistemi, di recente i lavori di Giuliano Preparata (1942/2000) ed altri, hanno reso più comprensibili sulla
base dell’elettrodinamica quantistica coerente i fenomeni in questione; gli stessi esperimenti di Zhadin
segnalanti che alla risonanza di ciclotrone degli ioni (nel caso dell’esperimento di Zhadin acido glutammico), nella soluzione appaiono picchi di correnti dell’ordine del 30% , appaiono molto vicini agli
aumenti di corrente che si producono nei circuiti elettrici corporei in risposta a segnali fisici coerenti di
varia origine (atmosferica, farmacologica, da materiali speciali ecc) .
Va anche annotato come in numerose misure si è osservata la pericolosità di queste anomalie magnetiche naturali sulla salute (cefalee, gastropatie, alterazione dello stato di attenzione ecc) e la (nostra)
attuale ignoranza sul tema non può fare altro che spingere a potenziare la ricerca teorica e sperimentale e lo sviluppo di tecnologie di controllo dei danni che queste anomalie magnetiche naturali, assieme ai campi elettromagnetici artificiali, potrebbero indurre sulla salute e sul benessere umano.
MODELLO MATEMATICO PRELIMINARE DELLE CORRENTI MISURATE
Alcuni autori (Rif. N° 21, 22) hanno analizzato i possibili effetti di natura non termici della radiazione
(ELF, Radio Frequenza, Microonde) a bassa intensità sulla fisiologia umana impiegando l’analisi dimensionale nel tentativo di definire un insieme completo di possibili interazioni biologiche con alte frequenze di deboli intensità (10 mW/cm2). Deducono inoltre che ogni meccanismo può trasferire, a elementi biologici piccoli quali molecole, cellule ecc., energia superiore a quella delle fluttuazioni termiche
dell’ordine di S/N«1. Quindi, in termini classici, questi meccanismi non possono procurare biologici
sensibili. Tuttavia non è possibile esclude che il trasferimento di energia su considerato non possa creare forze, ad es. di natura elettrorestrittive che, applicate a sistemi cellule, possano indurre effetti di
potenza sempre inferiore alle potenze termiche standard (.S/N«1). Se ne conclude che CEM di intensità inferiore a 10 mW/cm2 possono creare effetti biologici significativi con bassissima probabilità. Lungo
questa linea di pensiero, trattandola anche con i criteri bayesiani, tra probabilità a priori e a posteriori,
si perviene alla conclusione che bisognerebbe escludere ogni tipo di effetti biologici eventualmente generati da campi elettromagnetici deboli. Tuttavia questo approccio classico non tiene conto, come già
accennato, degli effetti di risonanza ciclotronica delle molecole e delle cellule, né delle correnti di superconduttività che si generano e altri fenomeni di natura quantistica (correnti ioniche, correnti coerenti).
In questo ambito, l’obiettivo prefissato è di elaborare e presentare un modello di
corrente elettrica che viaggia lungo la pelle che includa e integri tutte le componenti di elettrodinamica (classica) quantistica su citate che viaggiano lungo la rete biologica. L’analisi del tipo di correnti (classiche, quantistiche, superconduttive
ecc.) che si sviluppano è riportata nel Rif. N° 12. Il passaggio che si tenta di
spiegare è quello dalle correnti microscopiche a quelle macroscopiche che sono
essenzialmente misurate dallo strumento (EAV) che normalmente si impiega per
misurare, in fin dei conti, una corrente totale - per così dire macroscopica – che
include, integrati tutte le componenti suddette, quelle di superconduzione quantistica, quelle di elettrodinamica classica e quelle classiche ohmiche.
Tutto quanto sopra premesso, la ipotesi che si fa è che la corrente lungo la pelle
dell’uomo sia costituita di due componenti:
1. Corrente dovuta a un fluido completamente ordinato di particelle (ioni, elettroni) che si muovono in
fase con il campo e.m. prodotto dal generatore esterno e che produce il superfluido (GS SF) costituito da un sistema di gas di elettroni coerenti. In altre parole, Si abbandona il modello di elettrolita
di tipo “gassoso” e gli ioni non possono muoversi di moto aleatorio browniano secondo cui percorrono brevissime distanze ad altissima velocità (parecchie centinaia di metri al secondo) tra le collisioni
successive (paradosso kT).
In altre parole si considera la generazione di una corrente additiva prodotto dalla deplezione delle
orbite ciclotroniche degli ioni (ossia un termine controllato magneticamente all’interno della soluzione elettrolitica –acqua - del tessuto.)
2. La componente normale di elettroni costituita da un gas di quasi particelle con livelli di energia distribuiti, ad es. secondo la statistica di Fermi (approccio classico termico che segue la legge di Ohm,
le, leggi potenziali e la legge di Joule)
Nel primo caso, si identificano le seguenti correnti di effetti coerenti nel tessuto (ciascun strato della
36
pelle):
Ic = f (e.l., H,)
dove e.l. = elettroni liberi
H = magnetizzazione dell’acqua (hopping condution).
Nel modello classico, l’acqua viene polarizzata dai campi elettrici con polarizzabilità (con il modello di Debye) pari a:
αacqua = α0 + [μ2/3kBT]
che evidentemente produce una corrente di polarizzazione Ip nell’acqua.
Inoltre, vengono generate corrente di ioni (molecolari) dovute ai due tipi di forze (ponderomotrici e dispersive). Le forze ponderomotrici generano una differenza di potenziale (ddp) paragonabile a quella di una
sorta di diodo, mentre le forze dispersive generano una corrente
Ids = g [k / (f2 – f20)]
Questo tipo di corrente coerente non dissipa energia significativa.
Nel secondo caso, ossia in caso di corrente classica, si può calcolare il contributo della potenza istantanea
(tasso di energia dissipata dW/dt in un volume V) dalle correnti standard definita da:
∫V E J dv
(1)
E = intensità (V/m) del campo elettrico sinusoidale nel volume di pelle considerato.
J = Jps + Jsf = densità di corrente elettrica totale, somma della corrente standard lungo i 7 strati di
pelle umana e quella, supposta, di superfluidità lungo gli stessi strati di pelle, in A/m2.
La densità di corrente standard lungo i vari strati della pelle è data dalla
Jps = ∑71 Jisp
mentre la densità di corrente di superfluidità o coerenza è data da:
Jsf = ∑71 Jisf
La legge di Ohm può essere scritta, in questo caso, come:
(2)
∫V E J dv =
∫V σE2 dv =
∫V J2/ σ dv = dW/dt
j = e σ.
CONCLUSIONI
Attualmente la confidabilità del metodo e quindi i limiti di confidenza della corrispondenza fra i punti di
scala e le resistenze elettriche misurate sono ancora abbastanza flebili ma consentono,
all’osservazione e alla diagnosi del medico, di potere tentare di inferire una corrispondenza con le potenziali malattie e le potenziali patologia su riportate.
Il modello matematico presentato è ancora molto grossolano e basato su metodi potenziali elettrici
37
come è intrinseco alla teoria delle correnti elettriche classiche, mentre alcune delle correnti elettriche
che scorrono lungo la pelle umana a causa di CEM includono componenti quantistiche e superconduttive molto difficili da modellare e da “ridurre” a semplici correnti elettriche classiche.
Il modello su accennato di sviluppo delle correnti elettriche su riportato è solo l’idea di base per la impostazione del modello che si intende sviluppare nel futuro in modo più approfondito e rigoroso al fine
di pervenire ad un interpretazione teorica più consistente dei valori riportati nella Tabella N°1
Riferimenti :
1. Valenzi V.I.; Grieco U.; Garcia A.; Marinelli F.; Lozito A.; Messina B.: “Cutaneous electrical phenomena in the evaluation of the curative properties of sand marine environment: preliminary observation. CIRM Research; 3 (1): 1999.
2. Scalia M.; Sperini M.; Garcia A.; Dell’Anna C.; Valenzi V.I.; Messina B.;: “Gli ioni aerei”, Andromeda Editore 1998.
3. Comune di Roma- Dipartimento politiche ambientali e agricole: La rete di monitoraggio e la gestione dei dati della qualità dell’aria, 2001.
4. Preparata G.:QED Coherence in matter. World Scientific Singapore, (NJ), London, Hong Kong.
1995
5. Voll R.: I Punti di misurazione dell’elettroagopuntura secondo Voll. ML Verlag 1983
6. Rosendal T.: Further studies on the conducting properties of human skin to direct and alternating
current. Acta Physiol. Scand. 8, pp. 183-202,1944.
7. Ladu M.: Lezioni di Fisica. Monduzzi Editore, Bologna 1984.
8. AA. VV.: The role of quantum electro dynamics(QED) in medicine. Rivista di Biologia/Biology Forum 93 (2000) pp.267-312.
9. Burns, C.R.: “Study of skin impedance”, Electronics, 1950
10. Zhadin M.N., Novukov V.V., Barnesf.S. Pergola N.F. (1998) Combined action of static and
alternating magnetic fields on ionic current in aqueous glutamic acid solutions.
Bioelectromagnetics 19: 41-45.
11. Bianchi C., Lozito A., Meloni A. – Campi elettromagnetici: Tecniche di monitoraggio ambientale e
principi dell’interazione biologica - Quaderni di geofisica n. 22 (2002). Istituto Nazionale di Geofisica e Vulcanologia.
12. Giuseppe Quartieri, Vincenzo Valenzi, Artropatie meteosensibili e Skin Electric Parameters, CIFA
NEWS 36, July-December 2006.
13. Ordine degli Ingegneri di Roma: “Esposizione umana ai campi elettromagnetici ad alta frequenza”
Atti del Seminario, Dicembre 1994.
14. AIRM: Effetti stocastici da radiazioni”, Atti del XV Convegno Nazionale, Pisa 1997.
15. Paolo Bernardi, Progetto Nazionale MIUR/CNR-ENEA “Salvaguardia dell’uomo e dell’ambiente dalle radiazioni elettromagnetiche” Relazione Conclusiva Annuale III Anno (maggio 2003-2004).
16. Stefan Engstro, Joseph D. Bowman: Magnetic Resonances of Ions in Biological Systems Bioelectromagnetics 25:620^630 (2004)
17. M. Portaccio, P. De Luca, D. Durante, V. Grano, S. Rossi, U. Bencivenga, M. Lepore, D.G. Mita:
Modulation of the Catalytic Activity of Free and Immobilized Peroxidase by Extremely Low Frequency Electromagnetic Fields: Dependence on Frequency, Bioelectromagnetics 26:145^152
(2005)
18. S. Ravera, E. Repaci, A. Morelli, I.M. Pepe, R.Botter, and D. Beruto: Effects of Extremely Low
Frequency Electromagnetic Fields on the Adenylate Kinase Activity of Rod Outer Segment of Bovine Retina, Bioelectromagnetics 25:545^551 (2004)
19. M. Portaccio, P. De Luca, D. Durante, S. Rossi, U. Bencivenga, P. Canciglia, M. Lepore, A. Mattei,
A. De Maio, and D.G. Mita: InVitro Studies of the Influence of ELF Electromagnetic Fields on the
Activity of Soluble and Insoluble Peroxidase, Bioelectromagnetics 24:449^456 (2003)
20. Robert K. Adair: Biophysical Limits on Athermal Effects of RF and Microwave Radiation, Bioelectromagnetics 24:39^48 (2003).
21. Fro¨lich H.. Long range coherence and energy storage in biological systems. Int J Quant Chem
2:641–649; 1968.
22. Del Giudice, M. Fleischmann, G. Preparata, and G. Talpo: On the ‘‘Unreasonable’’ Effects of ELF
Magnetic Fields Upon a System of Ions, Bioelectromagnetics 23:522^530 (2002)
38
Management of the neurovegetative dystonias
in microgravity: first results
of the “Look and see” involving mineral water
(1) Chair of Biometeorology and Space Medi(2)
(3)
(4)
by V. I. VALENZI (1-2), G. BELISARIO (2), M.
C LUCCHETTA (3), G. ANDREONI (4), A. PISANI (3), A. SERIO (3), G. MENNUNI (3), G. E.
GIGANTE (2-5), M. V. RUSSO (2-6), P. AVINO
(2-7), A. FRAIOLI (3)
(5)
(6)
(7)
cine, Free LUDES University, Lugano, Switzerland
Biometeorology Study Centre, Rome
Specialisation School in Medical Hydrology,
“La Sapienza” University, Rome
Department of Bioengineering , Polytechnic
University, Milan
Chair of Applied Physics, “La Sapienza”
University, Rome
Chair of Analytical Chemistry, Molise University, Campobasso
Institute for Prevention and Safety at Work
(DIPIA), Rome
ABSTRACT
The experiments of Space Medicine performed in the last decade showed that gravity, or microgravity,
has an effect on the neurovegetative system. The acquisition of new data in this discipline has opened
numerous and interesting questions. First of all, it is not still clear if gravity directly acts on the neurovegetative system and its components or if its effect is influenced by the surrounding chemical-environment
that is directly influenced by gravity. Among the problems of still unsolved space flights there is the Space
Motion Sickness (SMS) coupled with cardiocirculatory diseases and performance status reaching such levels thus compromising the astronaut’s work during a space mission. One of the main scope of the BIOMET’07 mission is to investigate cures for some illnesses in microgravity such as baby’s vomit with waters
rich in bicarbonate (Ferrarelle). The first “look and see” results confirm the capability of the waters rich in
bicarbonates to protect the neurovegetative system at space levels. These “look and see” results of April
28th 2007 on Parabolic flight in G-0 at Cape Canaveral are only preliminary considerations and, of course,
other studies are necessary for confirming them.
STUDY OVERVIEW
This first experiment has shown how water rich in bicarbonate (Ferrarelle), which has been administered
in a blinded study, can oppose disorders related to Performance Status, the digestive system, the cardiovascular apparatus caused by gravity in 70% of astronauts at the first stages of Zero, Lunar and Martian
gravity.
PATIENTS AND METHODS
Four healthy volunteers have been involved in this research. Both in the two volunteers, which have been
administered water rich in bicarbonate (two, M/F 1:1), and in the control volunteers (two, M/F 2:0) respiratory and cardiac parameters have been recorded by means of PHEDRA system (produced by SxT srl,
Lecco, Italy). This system consists of a wearable multitest electrocardiograph (ECG etc.) giving the possibility to register an ECG derivation, heart beat and respiratory frequency in relation to movement (triaxial
acceleration) without continuity solutions. The variation of cutaneous resistance has been recorded by SEP
Analyser during the different gravity stages (Lunar, Martian gravity, hypergravity)
RESULTS
The two volunteers who have been administered water rich in bicarbonate (Ferrarelle) haven’t registered
any neurovegetative signs, sick feeling or vomiting. SEP values (normal value 95000 Ω) kept in a bioelectric homeostasis during the parabolic flight with a decrease in electric resistance values around 80.000.
ECG in study volunteers haven’t registered significant cardiac electric alterations; basal heart beat fre-
39
quency: 63±5, heart beat frequency in flight: 78±12; basal respiratory frequency: 12 ± 3, respiratory frequency in flight: 18±3.
CONCLUSIONS
These first results show the usefulness of calcic-bicarbonate mineral
water in order to control homeostasis systems of the digestive and
cardiovascular apparatus, to optimize performance status and to
prevent kinetosis caused by microgravity, indicating new applications
in space (ISS and future space colonies). In the light of the presented data, the authors recognize that space and earth studies with
a larger sample have to be necessarily implemented.
Sistema PHEDRA
40
SEP variations on subjects with chronic
constipation in idropinic treatment
by A. PISANI (3), V. I. VALENZI (1), P. SOTGIU (1), J. W. FRANCOIS (1), M. C. LUCCHETTA (3), M. GRASSI (3), A. SERIO (3), P.
AVINO (2), M. RUSSO (2), A. FRAIOLI (3)
(1) Istituto di Biometeorologia e Medicina Spaziale Libera Università degli Studi di Lugano
(2) Cattedra di Chimica Analitica Unimolise
(3) Scuola di Spec. In Idrologia Medica Roma1
In the Centro Sillene, a spa in Chianciano Terme, Italy, where from several decades many people affected by chronic constipation and liver diseases go to do mud bath and drink mineral water, we measured SEP (Skin Electric Parameters) in subjects with chronic constipation, before and after administration
of Acqua Fucoli, a rich mineral water (fixed residue 2690 mg/l, bicarbonate 425 mg/l, sulphate 1560
mg/l, calcium 647 mg/l, magnesium 79.5 mg/l) . This water reduces gastric and duodenal inflammation,
modulates intestine motility and secretion, increases liver and gall bladder activity and has diuretic effects
too.
Measures highlighted that, in subjects with constipation, the electrical resistance increased in physical
electric circuits, with a medium of about 43 scale unites of Sep, that corrispond at 130.000 Ω. After
administration of Fucoli water we saw a resistance fall, in medium at 39.000 Ω (70 us), with an
improvement of bioelectric performance due to an increase of physical electric currents, in accordance
with the Ohm’s law, I= V/R. These first bioelectric observations on rich mineral water activity, could open
a new window in the study of water action mechanisms in constipation.
Further observations and correlaton studies with clinical and laboratory data are necessary to understand
the rule of SEP to evaluate mineral water efficacy. Other 12 cases measured confirm these preliminar
data and open a new window on mechanism of action of Thermal Therapy.
EFFETTI BIOELETTRICI DELL'ACQUA FUCOLI
Ohm
90
80
70
PAZIENTE
Valore US
10 000
91
27 000
78
39000
70.5
47000
66.5
95000
50
100 000
48
130000
43
200000
32
220 000
29
300000
24
560 000
14
1000 000
8
us sep*
60
50
SEP BASALE 40
30
20
SEP DOPO SOMMINISTRAZIONE DI ACQUA FUCOLI
10
0
1
2
3
4
5
6
REFENCES
V.I.Valenzi, S. Grimaldi, G. Quartieri, G. E. Gigante; G. Mileto, G. Monaco: Osservazioni
sulle variazioni bioelettriche nell’uomo indotte da campi elettromagnetici in camera amagnetica.
Ricerca Aerospaziale Pag. 33-38, Anno XXI- N. 1. 2005
V.I.Valenzi, G.Monaco, S. Spada, P. Cimaglia, L.Petraccia, S.Palmieri, B. Messina
M.Grassi: Ruolo dei SEP (Skin electric Parameters) nello studio delle meteoropatie, Annali di Medicina Interna, 2003: 18, 164S - Proceedings Congresso SIMI Vincitore Premio CECIL .
Vincenzo I. Valenzi, Maria Luisa Roseghini: From Drug intolerance to a SEP (Skin electric Parameters) driven therapy. Some preliminar observation. Rivista di Biologia/Biology Forum 93
(2000) pp. 306-312.
41
A proposito del campo informatico
del potenziale vettore
by VINCENZO VALENZI
In una nota apparsa su internet Giuliano Preparata e coll., hanno concentrato l’attenzione sulle funzioni operative del potenziale vettore in proposito hanno scritto che :
Il campo elettromagnetico intrappolato ha con sé un compagno inseparabile, il "potenziale vettore",
quantità totalmente non misurabile nell’ambito della fisica classica, ma che, nella teoria quantistica
dei campi, influenza la fase di un sistema coerente. Il potenziale vettore, a differenza del campo, non è intrappolato, esso si estende ad una ampia regione circostante, senza trasportare
energia ma solo informazioni, ma esercitando una sua "influenza sottile", potremmo dire informatica, modificando la fase dei sistemi coerenti presenti.
Tra i vari sistemi coerenti si apre perciò la possibilità di un "dialogo sottile", una comunicazione senza
scambio di energia, che coinvolge solo le fasi, che sfugge perciò ad ogni misura di tipo parcellare
e può essere percepita solo da chi si pone in un ambito ondulatorio.
Accanto all’ordine della coerenza si pone il disordine del mondo gassoso, degli atomi isolati, localizzati "qui ed ora", sottoposti al regime della collisione, della fluttuazione termica e, nel loro insieme,
portatori di una temperatura e di una entropia.
La materia vivente è una sintesi tra coerenza e non coerenza. Negli interstizi dei domini di coerenza
dell’acqua, le molecole disciolte, inizialmente non coerenti, si muovono seguendo il richiamo selettivo, secondo un codice di risonanza tra frequenza, dei domini di coerenza, fino a costruire membrane
dotate di loro propria coerenza e perciò capaci di attirare, secondo le stesse leggi, altre molecole che
con le loro interazioni chimiche mutano la natura dei protagonisti e, attraverso la proprietà generale
della coerenza, le fasi e i modi di oscillazione dei campi coinvolti. L’"influenza sottile" del potenziale vettore si incarica poi di correlare tra loro tutte queste strutture coerenti nell’unità
del vivente. Nell'acqua liquida semplice, la frequenza oscillatoria del campo responsabile della coesione delle molecole è una sola; quando abbiamo a che fare con più sistemi, ognuno con la sua frequenza, tenendo presente anche che cambiano nel tempo, cominciamo ad avere un insieme di "note"
che variano nel tempo e non sono più singole, ma accordi, voci, messaggi. Sembra l'archetipo della
vita: da un insieme slegato di oggetti individuali, a un oggetto che è un "tutto". Questa può essere
una delle strade per capire l’emergere della coscienza dalla materia.
Queste considerazioni rappresentano lo sviluppo della coerenza agli studi di Ahranov, Bohm e Josephson e sembrano trovare applicazioni concrete oltre che nei sistemi biologici (fenomeni iperconduttivi
misurabili) anche nei sistemi di comunicazione. In proposito può essere utile riportare l’estratto di una
nota di Puthof che scrive come
”with avvent of quantum theory, however, the traditional picture change. In the prior art litterature,
the (vector and Scala potentials A and ¢) formalism has emerged as more fundamental because it
predicts certain quantum interferer effects that have been observed and are not apparent from the
(E, B) approach. This difference was first set forth in an unequivocable way in a seminal 1959 paper
by Ahranov and Bohm, entitled Significance of electromagnetic potential in the quantum theory” Physical Review 1959 and 1961.
In these papers it is shown that in certain two-leg electron-interferomete configuration in which the
potential A and ¢ are estabilished in a region of space, but B and E are absent . It is nonetheless possible for the potentials A and ¢ induce changes in electron quantum interference patterns.
That is , electron that are in an electromagnetic field-free region and therefore do not encoter an electric or magnetic field are notheless acted upon by the presence of the A and or the ¢ potentials.
Such an effect is now referred to broadly as a Ahranov- Bohm effect, and device have been built wich
demonstrate this effect in laboratory. For a recent overview, see, Y Imry aand R. A. Webb,” Quantum
interference and the Ahranov-Bohm effect” Scientific American” 260 (april 1989).
A second quantum interference effect demonstrate the independent reality of the (A,¢) potentials in
the absence of the (E,B) fields (and one which is significant for the technology disclosed by Puthof) is
a single-leg electron interferometer effect know as the Josephson effect; see R.P. Feynman,. The
Feynman Lectures on Physics 1965) The Josephson effect is based on the fact that the current density
J through a Josephson Junction ( which consist of two superconductors separate by a thin insulator)
Is determined by the magnitude of the potential A and ¢, independent of whether E or B are present.
42
C’è materiale per ulteriori riflessioni in ambito anche biologico dove cominciano ad essere più decifrabili azioni dei farmaci tramite la sola vicinanza nel range di un cm con induzione di fenomeni iperconduttivi.…Approfondimenti..sui..link
http://www.vglobale.it/VG/Articoli.php?UID=2015&suid=Primo+Piano
http://www.vglobale.it/NewsRoom/index.php?News=3731&ref http://www.colombre.it/montagnier
43
RAASSSSEEG
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NII IIN
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LII
The leader in news and information on low energy nuclear reactions
January 11, 2008 -- Issue #26
ANALYSIS AND PERSPECTIVES
5. The Widom-Larsen Not-Fusion Theory
http://front.math.ucdavis.edu/author/A.Widom
by STEVEN B. KRIVIT
[Note: This article is about 32 pages in length and contains about 12,000 words. Readers may skip to the
end if they would like a summary of my observations and conclusions. Readers may go to this Web site
for a brief technical overview of the theory or this Web site for a more detailed review of the theory.]
Contents
1. A Controversial Theory
2. Approach 1: Other Viable CMNS Theories, Part 1
3. Approach 1: Other Viable CMNS Theories, Part 2
4. Approach 1: Other Viable CMNS Theories, Part 3
5. Approach 2: Critique of Widom-Larsen Theory From CMNS Community
6. Approach 3: Critique of Widom-Larsen Theory From Scott Chubb
7. Observations and Conclusions of CMNS Community Response
8. Approach 4: Brief Critique of Widom-Larsen Theory From Richard Garwin
9. Resources
"We’ve established a sustained nuclear fusion reaction."
-Martin Fleischmann and Stanley Pons, March 23, 1989
" ... the bulk of the energy release is due to an hitherto unknown nuclear process or
processes ... "
-Martin Fleischmann, Stanley Pons and Marvin Hawkins, April 10, 1989
"There are some curious reports - not cold fusion, but people may be seeing some
unexpected low-energy nuclear reactions."
-Robert Park, on the subject of "cold fusion," March 22, 2007
(One of the most outspoken skeptics of "cold fusion" in the previous 19 years)
"It isn’t quite cold, and it’s probably not fusion, but something is going on."
-Sir Arthur C. Clarke, on the subject of "cold fusion," Dec. 15, 2007
(One of the most prominent supporters and philanthropists of "cold fusion" in the previous 19
years)
What convinced me, and many other people, of the reality of this field was the
experimental work. We analyzed the experimental studies, cross-referenced them among
44
various laboratories around the world over many years, found no significant errors of procedure or
data analysis and saw unmistakable correlation among the data.
If a viable theory explains 19 years of an experimental mystery, this should be cause for celebration,
not bitterness.
"Cold fusion" has followed a true path of the scientific process. It began with experiment, observation.
If Widom and Larsen are partially or fully correct, bravo to them! If other theorists are partially or fully
correct, bravo to them, as well. But show me the math, please.
That led me nowhere, and I paid little attention to theory for quite a while.
The first data point on this trail occurred on May 29, 2005. Vincenzo Valenzi, coordinator of the Centro
Studi di Biometeorologia of Rome, included me on a distribution that reported a seminar given by
Widom that was held at the University of Rome-3 on May 27, 2005, titled "Weak Interaction and Cold
Nuclear Reaction." Francesco Celani also sent an e-mail to his colleagues encouraging people to attend
the Widom seminar.
Valenzi said the seminar had been organized by himself, Gianni Degli Antoni and Flavio Fontana of
Milan, Paolo Manzelli of Florence and Fulvio Bongiorno of University of Rome-3.
Valenzi said the reaction from Bongiorno, professor of mathematical analysis, was that the
"presentation of Widom was very important and rich of possibility to develop something like a new
Manhattan Project."
But I didn't pay any attention to this matter until June 2005, when David J. Nagel, a professor at the
George Washington University encouraged me to look at the Widom-Larsen paper. Nagel, a physicist
who worked for 36 years at the Naval Research Laboratory, considered the Widom-Larsen paper
worthy of serious attention, and he thought that it might prove to be a viable mechanism for "cold
fusion." I told Nagel that it looked Greek to me, and he helped me understand a few of the basic
concepts.
In November, I got wind of another small conference in Italy on Oct. 14 that featured Widom. I also
saw a flurry of lively e-mail exchanges with many Italian scientists and a few Japanese scientists.
I read an optimistic quote about the Widom-Larsen theory from Lino Daddi, a physics professor with
the Italian Naval Academy.
"Perhaps we have a theory that explains all the anomalous phenomena," Daddi wrote.
"The transmutation observed from Yasuhiro Iwamura [Mitsubishi Heavy Industries] are explained
without the problematic multiple reactions" of others' theories, Daddi wrote.
I also received an e-mail from physics Nobel laureate Brian Josephson, who looked at the first WidomLarsen paper.
Josephson wrote that he considered their work “highly significant, since the physics may well be
sound.”
I looked back at my notes and found this report by Valenzi, translated by Yogi Srivastava, which I had
not read in detail at the time, from the day after the Widom seminar.
45
Rome: 28 May 2005.
On Friday, May 27, 2005, a meeting was organized at the University of Rome III to discuss the
controversial aspects shrouding low energy nuclear transmutations. The meeting was
addressed by Allan Widom, professor of theoretical physics at Northeastern University, Boston,
Mass., U.S.A., by Drs. Giuseppe Quartieri and Vincenzo Valenzi from the Center of
Biometrology, Rome, and by Dr. Francesco Celani from INFN, Laboratorio Nazionali di Frascati,
Italy. Professor Fulvio Bongiorno from the Department of Mathematical Analysis, University of
RomeIII, acted as the host and moderator of the assembly.
Widom presented a lively and personal account of his involvement with various aspects of low
energy nuclear reactions containing precise theoretical and experimental details. Quartieri and
Celani illustrated their own involvement with specific issues concerning nuclear reactions.
Valenzi discussed fundamental philosophical issues associated with the problem of nuclear
reactions and the hypothesis of clean energy production, which is completely biodegradable,
leaving no dangerous radioactive residue.
Such research has been subjected to extreme difficulty because of a remarkable opposition
from many sources. Hence, the “engagement” and the depth of the above contributions lead
one to recall the period around 1940 when far-reaching studies into the atomic nuclei were
carried out. One may even be tempted to bet on the success of the present endeavors.
At its base, there was an ample discussion covering two cardinal issues of security and
pollution, both essential.
An affectionate homage was paid to the memory of Professor Giuliano Preparata, a wellremembered master, whose scientific contributions in this field remain alive and well.
46
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S
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home | news | Il gran rimbalzo delle origini
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4 Luglio 07Fisica e materiali | COSMOLOGIA
Il gran rimbalzo delle origini
Un nuovo modello matematico per la nascita del nostro Universo: più che di un'esplosione, si sarebbe
trattato del collasso di un universo precedente
Cosa c'era prima del Big Bang? Un gruppo di ricercatori guidati da Martin
Bojowald, docente di fisica del Penn State Institute for Gravitational Physics
and Geometry (Usa), ha cercato di dare una risposta a questa domanda in un
articolo apparso su Nature Physics. Secondo un nuovo modello matematico
sviluppato dai fisici, il nostro Universo sarebbe nato dal collasso di un universo
precedente, e l'origine dovrebbe essere immaginata come un rimbalzo della
materia su stessa, più che come un'esplosione.
Bojowald è convinto che la teoria del Big Bang, considerata a lungo il miglior modello per la spiegazione
dell'origine dell'Universo, abbia rappresentato anche una grande barriera per la comprensione della sua
espansione. Come descritto dalla teoria della relatività di Einstein, il Big Bang – che prevede tutta la
materia concentrata in un volume pari a zero, con densità ed energia infinite - è un nonsense
matematico.
Attraverso i dati estrapolati con il modello Loop Quantum Gravity, la “macchina del tempo matematica”
messa a punto da Bojowald e colleghi, si sarebbe giunti a una nuova teoria che combina la relatività
generale con equazioni della fisica quantistica non ancora conosciute ai tempi di Einstein. Tornando
indietro nel tempo, gli scienziati hanno trovato un momento in cui l'Universo avrebbe possedutoun volume
minimo (diverso da zero) e un massimo di energia (non infinita) al di là del quale la forza di gravità
diverrebbe fortemente repulsiva. Si tratterebbe della prima descrizione matematica per stabilire
l'esistenza del Big Bounce e dedurre le proprietà dello stato quantistico del primitivo universo da cui si
sarebbe originato quello attuale.
Questa teoria quantistica-gravitazionale (Quantum-gravity teory) prevede anche che, in questo circolo di
universi che rimbalzano, uno dei parametri delle equazione del modello non “sopravviva” all'energia del
rimbalzo, cosicchè l'universo successivo non possa essere una replica esatta di quello precedente: una
sorta di dimenticanza cosmica intrinseca.(t.m.)
47
NATO Advanced Research Workshop
"Molecular Self-Organization in Micro-, Nano-, and
Macro-Dimensions: From Molecules to Water,
to Nanoparticles, DNA and Proteins"
dedicated to Alexander S. Davydov's 95th birthday
Bogolyubov Institute for Theoretical Physics, National Academy
of Sciences of Ukraine, Kyiv, Ukraine
June 8 - 12, 2008
Co-Directors:
Prof. Nino Russo
Department of Chemistry
University of Calabria
Arcavacata di Rende, Italy
E-mail: [email protected]
Prof. Victor Ya. Antonchenko
Vice-Director
Bogolyubov Institute for Theoretical Physics
Kyiv, Ukraine
E-mail: [email protected]
www.bitp.kiev.ua
48
INVITING CARD
XVI INTERNATIONAL CONFERENCE AND DEBATING SCIENTIFIC CLUB
New Information Technology in Medicine, Pharmacology, Biology
and Ecology
IT + M&E`2008
Ukraine, Crimea, Yalta-Gourzuf, from May 31 till June 9 2008
CONFERENCE ORGANIZERS
Ministry of Health and Social Development
Russian State Medical University
Institute of Bioorganic Chemistry of RAS
Research Institute of Normal Physiology of RANS
All-Russian Scientific Center on Biologically Active Substances Safety
Institute of Neurosurgery of RAMS
Russian Center of Functional Surgical Gastroenterology
Kuban State Medical University
Institute of Neurology of RAMS
Moscow State Academy of Instrument-Making Industry and Information Science
Coordinating Advice Council of Moscow State University on Life Sciences
Academy of New Informational Technologies
INTERNATIONAL ORGANISING COMMITTEE
Chairman – Prof. E.L. Gloriozov
Co-chairmen:
Ass. Member of RAS S.O. Bachurin
Prof. S. Khoroshkov
Ass. Member of RAS V.M. Lipkin
Prof. V.G. V.G. Nikitaev
Prof. T.G. Robostova
Acad. of RAS V.S. Shestakov
Acad. of RAMS M.B. Shtark
Prof. A.Kh. Tambiyev
Prof. T.G. Tolstikova
Acad. of RAS N.S. Zefirov
Prof. M.N. Zhadin
Members of the Program Committee
V.N. Bagratashvili, N.V. Bobkova, A.A. Boldyrev, R.K. Chajlakhyan, L. Giuliani, V.V. Gnezditsky,
Tamilla Khalilova, V.N. Khristoforov, V.A. Kordyum, G.N. Krementchugsky, A.N. Kurzanov, V.Z,
Lankin, V.V. Markina, V.I. Masycheva, V.K. Mazo, V.N. Novosel’tsev, V.I. Ofitzerov, Yu.A.
Romanov, L. Ruzer, E.M. Trukhan, E.M. Troshina, K.V. Zaytchenko.
SUBJECT MATTER OF THE CONFERENCE
•
Genomics. Genes and diseases.
- Acad. of RAS Prof. S.V. Shestakov
•
Medical Physics: Diagnostics and treatment
49
1.
2.
3.
4.
Quantum Medicine
Lasers in Medicine
Problems in Chronobiology and Cronomedicine
Medical informational systems for decision-making support
- Prof. V.S Khoroshkov, Prof. V.N. Bagratashvili,
Prof. V.G. Nikitaev, Prof. V.N. Khristoforov
•
Medical Chemistry as a method of directional search of new drugs
- Acad. of RAS Prof. N.S. Zefirov, Ass. Member of RAS S.O. Bachurin
•
Problems of Pharmacology
- Prof. T.G. Tolstikova
•
Neurochemistry and Neuropharmacology
- Prof. A.A. Boldyrev, Prof. V.Z. Lankin
•
Problems and prospect of cell therapy
- Prof. Yu.A. Romanov
•
Mathematical modeling in Biology and Medicine
- Prof. V.N. Novosel’tsev
•
Problems, methods, and produce of modern Biotechnology
- Prof. V.K. Mazo, Prof. A.Kh. Tambiyev
•
Novelty in laboratory diagnostics of infectious diseases
- Prof. V.I. Ofitserov
•
New technologies in gastroenterology
- Prof. A.N. Kurzanov
•
Diagnostics and treatment of urgent states in Medicine
- Prof. V.G. Vasil’kov
SATELLITE SYMPOSIUMS
•
Progress in modern Bioorganic Chemistry and prospect in its application
Chairman - Ass. Member of RAS V.M. Lipkin
•
Experimental Biology and Clinical Medicine in the third anniversary
Chairman – Prof. G.N. Kremenchugsky
•
Computerized Biomedical devices and systems
Chairman – Prof. K.V. Zaychenko
•
Biophysical foundations of new Medical Technologies
Chairman – Prof. E.M. Trukhan
•
Radiation Ecology
Chairman – Prof. L Ruzer (USA)
• Quantum Electrodynamics of condensed matter and problems in Biology and Medicine
Chairmen – Hon. Sci. of RF Prof. M.N. Zhadin, Prof. L. Giuliani (Italy)
50
•
Neuroscience, Neurology, and Clinical Neurophysiology.
Chairman – Prof. V.V. Gnezditsky
•
Modern problem of epileptology
Chairman – Prof. L.R.Zenkov
•
Oxidative stress and free radical pathology
Chairman – Prof. V.Z.Lankin
•
Haemoglobins: structural and functional aspects
Chairman – Prof. A.F.Topunov
ROUND-TABLE DISCUSSION
“Gourzuf initiative – survival in the variable world”
Leader – Prof. V.A. Kordyum
***
LECTURE PRESENTATION
Working languages of the Conference: Russian and English.
Lectures are presenting only as the files in the “.doc” Microsoft Word format transmitted as an
enclosed file by your E-mail. Demonstration should be prepared using Power Point in English.
WE ASK YOU TO KEEP THE FOLLOWING RULES:
•
Format A4, font: Times New Roman - 10, Spacing between lines - 1; 95 signs in a line.
•
All figures and diagrams should be grouped.
•
For complicated drawings it is desirable to send their printed copies.
We accept lectures no more then three pages including text of abstract (format A4) in English. On
the first page there should be written the name of your lecture. Next line: the first name and family
name of each author of this lecture; Next line: name of the organization, address of this organization,
phone, fax, e-mail address. Before the text of the lecture its annotation should be given (about the half
of page in English). It is possible to place one or two black-and-white figures within the text without
increasing the volume of general text of the lecture (total volume no more then 3 pages). The figures
should be inserted into the text of the lecture. The text will be published in the Proceedings of our
Conference. The book of Proceedings will be given to main lecturers in the Crimea at their arrival.
***
ORGANIZATION FEE
The organization fee (150 euro) from each participant should be sent not later than April 20, 2008 to
address of Chairmen of the Organizing Committee Gloriozov E. L. by use of the service of American
Express or Western Union. Address: Gloriozov E. L., Maliy Kazenniy per. 8 fl. 21, Moscow 105064
Russia. E-mail address: [email protected] The organizing fee includes the following expenses:
• Publication of Conference Program and Conference Proceedings
• Rent of conference halls and of office equipment
51
•
•
Transportation of participants from Simferopol to Gourzuf in the day of arriving and from
Gourzuf to Simferopol in the day of their departure
Payment for participation in the general banquet.
The lecture text should be sent not later than April 20, 2008 to two addresses
simultaneously:
to Prof. Mikhail Zhadin by E-mail address: [email protected]
to scientific secretary of the Conference by E-mail address: [email protected]
The Proceedings of the Conference will be published as application to the Russian journal “Open
Education”.
The lectures will be published only in the case of receiving Organizing fee before April 20, 2008.
PAYMENT FOR RESIDENCE AND NOURISHMENT
The payment for hotel suite in (first class double room) together with nourishment (three meals a
day) is about 80 euro a day. If you want to make the reservation of hotel, you can send payment for it
together with organizing fee to the same address.
CRUCIAL DATES
Till April 20 – reception of Organizing fee.
Till April 20 - reception of lecture texts.
Till April 20– reception of payment for hotel reservation.
May 30 – the day of participant’s arrival.
• May 31 - organizing session of ICEMS (International Committee of Electromagnetic Safety)
• June 1 – the Conference opening at 15.00.
• June 2 - satellite symposium “Quantum Electrodynamics of condensed matter and problems in
Biology and Medicine”
ARRIVAL OF PARTICIPANTS
The presumptive date of participant’s arrival is May 30 and supposed place of arrival is Simferopol
airport. Special trip of bus will transport you from Simferopol airport to hotel in Gourzuf. The bus
route is through the picturesque Crimean Mountains and lasts no more than two hours. Try to adjust
the time of your arrival to Simferopol with us and, if it is possible, with other foreign participants
known to you.
52
Centro Studi di Biometeorologia onlus
Il cinque per mille per il CSB con il codice fiscale: 05 751 781 005
From more than one year ago, Prof. SABINO PALMIERI is not anymore with us. He was a frind of all
the villingness youngs that use to meet with friendship and rigour typic of a big scientist and solidgieracurally he has been Aeronautical General and Director Manager of the Military Aeronautics
Metereologic Service.
He has been a example and a sample for young researchers and ,we could say, also for not anymore
young professors that should reflect on his rigour lesson and of service to the University Institutions.
Critically, it could be said that this request of capability appear to be ever stronger and recongnised by
the researchers communitiy.
Let us report, now, the first three Google links for getting the ideas of the actuality and importance of
Prof. Sabino Palmieri work and his science and life lesson.
Associazione Italiana di Agrometeorologia
I had receind the new of professor Sabino Palmieri death, hold in Rome on ... Sabino Palmieri
leaves a scinetific vacuum very difficult to fill ...
www.agrometeorologia.it/articoli_fondo.shtml - 79k - Copia cache - Pagine simili
[PDF]
0-1 Premio SIMA "Sabino Palmieri "
File: PDF/Adobe Acrobat - Versione HTML
Premium SIMA "Sabino Palmieri". For Younf researchers on Meteorology and ... Sabino. Palmieri.
The competition is stated for young distinguished researcheristinti with ...
www.ucea.it/concorso/Premio_SIMA_2008.pdf - Pagine simili
0-2 CIFA/ICEF - International Committee for Research and Study of ...
Iwith a memory ib the hurban climate, Sabino Palmieri belongign ti the University of Rome "La
Sapienza" has treated the relationship between climate and climate disconfort....
www.cifa-icef.org/news_30_ita.html - 22k - Copia cache - Pagine simili
0-3 CIFA/ICEF - International Committee for Research and Study of ...
CIFA News 31 Janvier-March 2003. Cheaf Editors: Piero Faraone, Baldassare Messina, Sabino
Palmieri. INDEX. - Editorial S.Palmieri, Co-Editori in Capo. ...
www.cifa-icef.org/news_32_ita.html - 25k - Copia cache - Pagine simili
On Wensday 23th of Aprile 2008 at 16.00
c/o University Rome3 “Room N. 20”
Via della Vasca Navale 109 Rome Italy
Workshop
The contribution to science and ethic of Sabino Palmieri
The legacy of Sabino Palmieri in the Biometeorology and in the Aerospace Research
Giuseppe Quartieri (Scinetific Committee Coordiantor of “Aerospace Research”
Magazine).
Environmental factore and cancerogenesis (Piero Quercia, INFN associate)
Atmosferic pollutionmass tranfer phenomena
Pasquale Avino, Mario Russo (Analitic Chemistry Professor at Unimolise)
Atmosferic pollution in cities and mountin areas.
Luca Lepore, Domenico Brocco (CSB)
Mathematical Model for the climate control. Fulvio Bongiorno (Matem. Dept. Rome3)
Programma:
http://www.vglobale.it/Outlook/viewOutlook.php?Meet=2998&ref=2
Info [email protected] Tel 00393398865570 skipe: cifanews
53
NEEW
M CIIF
OM
RO
FR
SF
A
WS
FA
The general aim of CIFA is to organize, on international scale, interdisciplinary
cooperation in the research and scientific investigation of environmental factors responsible for
fluctuating phenomena in exact, natural and human sciences. In this connection CIFA is especially
concerned with the development of research work putting in evidence, and possibly identifying, all
factors directly or indirectly involved in fluctuating phenomena, and the systems sensitive to them.
This will concern as well as applied research.
CIFA*
est la siegle social du Comite International de Rescherche ed d’etude de Facteurs de
l’Ambiance). In english is ICEF : International Committee for research and study of Environmental
Factors.
THE COMMITTEE IS A NON-PROFIT ORGANIZATION
President : Vincenzo I. Valenzi email [email protected] ; phone 00393398865570 .
Onourary President : Boris Vladimirskij, Crimean Astrophysical Observatory, 6/a-24, p/o Nauchiny, 334413
Crimea (Ukraina) , email: [email protected] .
Vice-Presidents : Piero Faraone (presents the European Community) ; 141 Via Porpora, 20131 Milano (Italy) phone
02 26142609 ,email: [email protected] ;Internat.Academy of Science Member, Milano, Italy ; Honorary BIOCOS
Member, University of Minnesota-USA ; past Medic.Director of Hygiene Lab.of Roma and his Province.
Victor Martynyuk (presents the Euro-Asian Communities) Crimean Scientific Center of NAS and MES of Ukraine,
Vernadsky ave., 2 Simferopol, Crimea, 95007 UKRAINE, tel./fax: +38-0652-545413;tel. +38-050-6535592., email: [email protected] , Web:http://www.science-center.net/cbc/index_e.php .;
General Secretary’ : Paolo Manzelli , Director of LRE/EGO-CreaNet – University of Florence
Dipartimento di Chimica , Polo Scientifico 50019 -Sesto F.no- 50019 Firenze- Via Della Lastruccia 3 email
: [email protected] ; phone: +39/055-4573135
The General Archive of CIFA from 1969 to 1993 is at University of Bruxelles, and it is now in reorganizing.
This G. Archive is from 1993 at Puschino-University, where is actually, the Head Office of CIFA.
CIFA NEWS * * is published in cooperation between Centro Studi di Biometeorologia Onlus, CIFA and
TESLA (Tutela Elettromagnetica e Studio Livelli Ambientali ).
Scientific Board : Piero Faraone, Baldassarre Messina, Giuseppe Bonacina, Giovanni E. Gigante, Sebastiano
Spada, Settimio Grimaldi, Mario V. Russo .
Editorial Board: Piero Faraone,.Alvaro Garcia, Pasquale Avino, Gabriella Belisario.
Editor Responsible: Vincenzo I. Valenzi t. 0039 339 8865570 . Past Resp. Edit. Carmen Capel Boute (19142003)
The Archive of CIFA NEWS is in old Head Office at Université Libre de Bruxelles , Av.F.D.Roosvelt 50 (C.P.
196)1050 Bruxelles ,from 1969 to the first sem. of 2001,included ; and after from 2th of 2001, this G. Archive is in
Head Office of CIFA in Rome .
CIFA website
: http://www.cifa-icef.org/, Webmaster: Dr.Natalia Udaltsova, 2336 Welsh Ct., Walnut
Creek, California, 94598, USA. E-mail: [email protected] Phone: 1-925-932-8028
54
IL CINQUE PER MILLE ALLA
BIOMETEOROLOGIA csb
codice fiscale 05 75 17 81 005
http://www.agenziaentrate.it/ilwwcm/resources/file/eba0b0029834033/elencoA_A-C.pdf
…per continuare ad acchiappare nuvole …..
New Energy Times
- [ Traduci questa pagina ]
The only known presentation of the theory so far was at an Italian conference, "Coherence
2005," organized by Vincenzo Valenzi, a researcher with the ...
www.newenergytimes.com/news/2005/NET13.htm - 46k - Copia cache - Pagine
simili
[DOC]
PDF]
RB Convegno QED prova
Formato file: PDF/Adobe Acrobat - Versione HTML
The Meeting was organized by “Centro Studi di Biometeorologia”. CONTENTS. G.
Preparata. QED & Medicine. B. Messina. Past and Future in Medicine. G. Talpo. ...
www.tilgher.it/chrCorrelati/upload/doc/Abs_Convegno_QED.pdf - Pagine simili
[PDF]
COMUNICATO STAMPA
Formato file: PDF/Adobe Acrobat - Versione HTML
Centro Studi di Biometeorologia CSB Onlus. Via Caio Mario,6/a - 00192 Roma [email protected] - 339 886 5570. COMUNICATO STAMPA ...
www.regione.sicilia.it/.../argomenti/documentazione/pdf/SPACELAND_2007_COMUNICATO_STAMPA.pdf
- Pagine simili
Il Nuovo Medico d'Italia on line
di Vincenzo Valenzi (*). Le intolleranze farmacologiche possono essere identificate ....
Vincenzo I. Valenzi CSB; Carlo Messina SIAMEG; Alvaro Garcia CSB; ...
www.numedionline.it/numedi/arc2001/0201/08.html - 18k - Copia cache - Pagine simili
MIUR - Innovazione Tecnologica - News
(Vincenzo Valenzi e Giuseppe Quartieri, Centro Studi di Biometeorologia - Roma) ...
Vincenzo Valenzi e da altri colleghi durante il Convegno. ...
www.istruzione.it/innovazione/news/2004/open_net.shtml - 27k - Copia cache - Pagine
simili
[
CSB
Formato file: Microsoft Word - Versione HTML
CSB AFF. Centro Studi di Biometeorologia di Roma Associazione Fisica di Frontiera di
Milano. ON-NS. Open Network for New Science di Firenze ...
www.vglobale.it/pub/Allegato/coherence2006.doc - Pagine simili
Vincenzo Valenzi | RadioRadicale.it
[117457] - "Qualità dell'aria e salute" org. dal Centro Studi di Biometeorologia (c/o Salone
Conferenza dell'UCEA - Via del Caravita) ...
www.radioradicale.it/soggetti/vincenzo-valenzi - 38k - Copia cache - Pagine simili
Villaggio Globale - Trimestrale di ecologia - Rubrica
(* Centro Studi di Biometeorologia, Roma ** Cattedra di Chimica Analitica Università del
Molise) A relationship between excessive hygiene and antibiotic use ...
www.vglobale.it/VG/viewRubrica.php?UID=337&nuid=29&suid=Dossier - 43k Copia cache - Pagine simili
ON STORM GLASS AND THE METEREOLOGY
- [ Traduci questa pagina ]
Paolo Manzelli*, Giuseppe Quartieri**, Vincenzo I. Valenzi***, Giorgio Monaco***. *
Chemical Physicist - University of Florence, Italy ...
www.edscuola.it/archivio/lre/on storm glass.htm - 16k - Copia cache - Pagine simili
55
Untitled Document
Centro Studi di Biometeorologia di Roma Associazione Fisica di Frontiera di Milano ...
Aula Ingegneria n15 Università degli Studi di Roma RomaTr ...
www.loscrittoio.it/Pages/PM2-1005.html - 43k - Copia cache - Pagine simili
rivista ricerca aerospaziale
Vincenzo Valenzi e Giuseppe Quartieri. Jerome Benveniste (ESA Frascati), Angelo R.
Bibbo (Roma), Francesco Celani (INFN Frascati), Giovanni Colella (Roma), ...
www.ibneditore.it/ricerca.htm - 34k - Copia cache - Pagine simili
PDF]
02 indoor
Formato file: PDF/Adobe Acrobat - Versione HTML
Centro Studi di Biometeorologia, IBR Italia, Roma. 3. Università del Molise, Facoltà di
Agraria (DISTAM), Cattedra di Chimica Analitica ...
www.fsm.it/gimle/26/4s/02.pdf - Pagine simili
CAT.INIST
- [ Traduci questa pagina ]
AVINO Pasquale ; DE LISIO Vincenzo ; GRASSI Marcello ; LUCCHETTA Maria C. ;
MESSINA Baldassare ... RUSSO Mario V. ; SPADA Sebastiano ; VALENZI Vincenzo I. ; ...
cat.inist.fr/?aModele=afficheN&cpsidt=16153684 - Pagine simili
President Hotel Pietracuap
... il laboratorio Biometereologico "Giuliano Preparata" collegato con il Centro Studi di
Biometeorologia Onlus di Roma diretto dal Professor Messina. ...
www.pietracupa.com/pietracupa/iltempo.htm - 6k - Copia cache - Pagine simili
RB Sermonti
... tenutosi nella sala conferenze del Rettorato, presso l’Università “La Sa-. pienza” di Roma,
il 13 dicembre 2002. Organizzazione di Vincenzo Valenzi. ...
www.tilgher.it/manager/googlepdf.aspx?file=riv_t4a8f3o3019.pdf - Pagine simili
PDF]
Scienza, Cosmologia e creatività a Firenze nella Settimana Europea ...
(Vincenzo Valenzi e Giuseppe Quartieri, Centro Studi di Biometeorologia - Roma).
Commemorazione, da parte del Prof. Valenzi, dello scienziato Jacques ...
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Scienza e Conoscenza
Il caso Benveniste. Alla sua memoria e a quella dell'acqua. Di Vincenzo Valenzi di
Vincenzo Valenzi. Il Caso Benveniste: il Nikola Tesla della biologia? ...
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[DOC]
Relazione per la conferenza sugli Archivi Benveniste alla UNILUDES ...
Formato file: Microsoft Word - Versione HTML
Vincenzo Valenzi ed il Comitato Organizzatore di questa importante riunione .... Valenzi
Vincenzo Il ruolo dell’elettrodinamica quantistica in medicina. ...
www.vglobale.it/pub/Allegato/TIENGO_07.doc - Pagine simili
CIFA/ICEF - International Committee for Research and Study of ...
Centro Studi di Biometeorologia, **ISPESL CB. Nel corso del Convegno sul contributo di
Giuliano Preparata alla Fisica ed alla Biologia tenutosi a Roma il 13 ...
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MASTER II LIVELLO
Formato file: PDF/Adobe Acrobat - Versione HTML
secondo il Prof. F.Halberg. 3. M-PSI/02. 1. Vincenzo Isabella. Valenzi. (Contratto).
Contenuti. Principi di Biometeorologia ...
www.med.univaq.it/medicina/files/2005/195.pdf - Pagine simili
PDF]
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ABORATORI AZIONALI DI RASCATI
Formato file: PDF/Adobe Acrobat - Versione HTML
We are glad to Dr. Vincenzo Valenzi (Univ. Roma “La Sapienza”) that introduced our. work,
and problematic, to the Director of INTERNET blog (about ...
www.lnf.infn.it/sis/preprint/pdf/getfile.php?filename=LNF-06-20(P).pdf - Pagine simili
[PDF]
Le nuove fronti
Formato file: PDF/Adobe Acrobat - Versione HTML
di Vincenzo Valenzi. Dopo Marcello Pera, Presi-. dente del Senato che ha aperto. nella
primavera di quest'anno interpretazione, ...
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New Energy Times
- [ Traduci questa pagina ]
Vincenzo Valenzi, coordinator of the Centro Studi di Biometeorologia of Rome, included
me on a distribution that reported a seminar given by Widom that was ...
www.newenergytimes.com/news/2008/NET26.htm - 181k - Copia cache - Pagine
simili
AGENZIA FUORITUTTO
Roma, 1 dicembre ’07 (Fuoritutto) Il libro “Wilhelm Reich – Una formidabile avventura
scientifica e umana di Luigi de Marchi e Vincenzo Valenzi “ (Macro ...
www.agenziafuoritutto.it/Numeri%20precedenti/anno%206%20num%2042%20%201%20dicembre%202007.htm - 25k - Copia cache - Pagine simili
sedano fa bene all’amor | internettuale.net
1 vincenzo valenzi 23 Dicembre, 2007 alle 17:04. Il tema dell’eros è importante per la vita
quotidiana di ognuno. A tal proposito vorrei ricordare il ruolo ...
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E cosa dire dei 21 grammi dell’anima? la mappa di un’esperienza ...
Luigi de Marchi, Vincenzo Valenzi,. Wilhelm Reich. La ricerca di un’energia vitale che
condiziona la vita e il benessere degli uomini ha radici molto ...
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Vincenzo Valenzi | RadioRadicale.it
Una formidabile avventura scientifica e umana presentazione del libro di Luigi de Marchi e
Vincenzo Valenzi (Ed. Macro). DIBATTITO ...
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CIFA/ICEF - International Committee for Research and Study of ...
V.Valenzi, M.L.Roseghini, U.Grieco, V.Caprioli, V.DeLisio, B.Messina . .... Mariano Bizzarri,
Jacques Beveniste, Piero Faraone e Vincenzo Valenzi. ...
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[DOC]
CSB
Formato file: Microsoft Word - Versione HTML
Vincenzo Valenzi: Dalla Biometeorologia alla farmacoelettrodinamica. ... Vincenzo Valenzi
Resp. del Centro di Biofisica Clinica della Cattedra di Medicina ...
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Nuove Frontiere in Medicina
Umberto Grieco nel corso delle puntate del programma televisivo di Rete News ... e la
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Nuovo Medico d'Italia on line
A cura del Centro Studi di Biometeorologia/Laboratorio Biometeorologico di .... Una
prima iniziativa, lanciata dal laboratorio di Biometeorologia del Medio ...
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Il Nuovo Medico d'Italia on line
Centro Studi di Biometeorologia Onlus (Direttore prof. B. Messina ) In collaborazione con il Centro
Interdipartimentale di Ricerca per l’Analisi dei Modelli ...
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Altri risultati in www.numedionline.it »
57
CENTRO STUDI DI BIOMETEOROLOGIA E ASSOCIAZIONE T
Il Centro Studi Biometeorologia el’Associazione TESLA, hanno stipulato un protocollo di
intesa per lo studio dei campi elettromagnetici e degli effetti ...
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messina_baldassare
Presidente dell'Associazione italiana di Idroclimatologia Medica, già Direttore dell'Istituto di
Idrologia .... ***Centro Studi di Biometeorologia di Rom.
www.comen.org/messina_baldassare.html - 18k - Copia cache - Pagine simili
CIFA/ICEF - International Committee for Research and Study of ...
Il Centro Studi di Biometeorologia da questo numero curerà il CIFA NEWS che per oltre
trent’anni è stato redatto a Bruxelles. I primi 29 editoriali erano ...
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Sökresultat för site:www.numedionline.it "Biometeorologia"
7 osumaa
Träffar på webben •
Il Nuovo Medico d'Italia on line i ricercatori V. Valenzi, M. L. Roseghini, U. Grieco, V. Caprioli, B. Messina*, V.
De Lisio** (* Centro Studi di Biometeorologia, **ISPESL CB ), hanno ...
www.numedionline.it/numedi/arc2003/0103/11.html · italia
Välimuistissa · Samankaltaisia sivuja
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Il Nuovo Medico d'Italia on line A cura del Centro Studi di Biometeorologia/Laboratorio Biometeorologico di ....
Una prima iniziativa, lanciata dal laboratorio di Biometeorologia del Medio ...
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Välimuistissa · Samankaltaisia sivuja
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Il Nuovo Medico d'Italia on line Centro Studi di Biometeorologia Onlus (Direttore prof. B. Messina ) In collaborazione
con il Centro Interdipartimentale di Ricerca per l’Analisi dei Modelli ...
www.numedionline.it/numedi/arc2001/0201/08.html · italia
Välimuistissa · Samankaltaisia sivuja
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Il Nuovo Medico d'Italia on line La biometeorologia e la meteorologia applicata vivono un momento particolarmente
... Vincenzo Valenzi (Coordinatore del Centro Studi di Biometeorologia) ...
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www.numedionline.it/numedi/arc2002/0302/07.html · italia
Välimuistissa · Samankaltaisia sivuja
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Il Nuovo Medico d'Italia on line Negli ultimi tre secoli, dopo la scoperta dell’elettricità, gli studi ripresero
vigore con numerosi studiosi impegnati nella biometeorologia. ...
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Il Nuovo Medico d'Italia on line Maria Luisa Roseghini Dip. Farmacologia - Univeristà La Sapienza Vincenzo Valenzi
Centro Studi di Biometeorologia - Roma ...
www.numedionline.it/numedi/arc2002/0902/12.html · italia
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Il Nuovo Medico d'Italia on line ­ Sommario Cultura L’influenza delle condizioni atmosferiche sulla salute umana non è certo frutto
della fantasia popolare: una scienza, la biometeorologia, la studia da tempo ...
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JANUARY-APRIL 2008
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