Europass Curriculum Vitae - Facoltà di Farmacia e Medicina

Europass
Curriculum Vitae
Personal information
First name(s) / Surname(s)
Address(es)
Telephone(s)
Fax(es)
E-mail
Nationality
Vincenzo Cuomo
Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy
064454295
0649912480
[email protected]
Italian
Date of birth 03/12/1947
Gender
male
Occupational field Academia: full professor of Pharmacology (SSD BIO/14 Pharmacology)
Work experience
Assistant Professor, Institute of Pharmacology, University of Bari (Italy)
Associate Professor, Institute of Pharmacology, University of Bari (Italy)
Full Professor of Pharmacology, Institute of Pharmacology, University of Bari (Italy)
Full Professor of Pharmacology, Dept. of Physiology and Pharmacology “V. Erspamer”
Sapienza University of Rome
1973-1980
1980-1985
1986-2001
2001-present
Visiting Professor, Institute of Toxicology, University of Zurich (Switzerland) and
Dept. of Environmental Health Sciences, Johns Hopkins University (Baltimore, USA)
1979-1983
Occupation or position held Full Professor of Pharmacology, Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza
University of Rome, Italy
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Surname(s) First name(s)
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Main activities and responsibilities
Research activity
Author of 244 publications on scientific journals and of several books and book chapters in the field of
Neuropharmacology and Neurotoxicology. Dr Cuomo’s research activity has been mainly addressed
to the evaluation of neurobehavioural, neurochemical and electrophysiological changes produced in
rats by the developmental exposure to psychotherapeutic agents, drugs of abuse, and environmental
chemicals. More recently he has explored the effects of chemicals influencing the endocannabinoid
system in animal models of psychiatric disorders. In particular, he has explored the role of
endocannabinoids and related lipid signals in the modulation of cognitive functions, feeding behaviour,
anxiety and mood tone.
All these researches have been funded by WHO, EPA, Italian Ministry of Education, National
Research Council, Italian Ministry of Health.
Other scientific activities and Professional Memberships
1986-1992
Secretary General of the Italian Society of Toxicology
1989-1995
Member of the Steering Committee of WHO/IPCS (Collaborative Study on
Neurotoxicology Assessment)
1989-1993
Member of the European Interlaboratory Study Group on Behavioral Teratology
1991-1993
Member of the Executive Committee of EUROTOX (European Society of
Toxicology)
1993-1996
Member of the Executive Committee of the Italian Society of Neurosciences
1995-1997
Member of the Executive Committee of the Italian Society of Pharmacology
1997-1999
General Secretary of the Italian Society of Pharmacology
1999-2003
President of the Italian Society of Pharmacology
2006-2010
Member of National University Council
2001-present
Director PhD School of Toxicology
2001-2006
Director Department of Pharmacology of Natural Substances and General
Physiology
2008-present
Member of the Scientific Committee of the School of Pharmacy, Tor Vergata Univ.,
Rome
Member of the editorial board of the following international scientific journals:
Neurotoxicology and Teratology (Plenum Press, N.Y, USA)
Neuroscience Research Communications (J. Wiley & Sons Ltd., Chichester, Sussex, England)
Pharmacological Research (Co-Editor) (Academic Press, London, England)
Toxicology Letters (Elsevier Science, Amsterdam, The Netherlands)
Asian Journal of Pharmacological Sciences
World Journal of Pharmacology (WJP, Ocean International Center, No. 62 Dongsihuan Zhonglu,
Chaoyang District, Beijing 100025, China).
World Journal of Clinical Pediatrics (Ocean International Center, No.62 Dongsihuan Zhonglu,
Chaoyang District, Beijing 100025, China)
European Journal of Neurodegenerative diseases
Referee for several International scientific journal of the field of Pharmacology and Toxicology and
referee for several national and international grant programs
Name and address of employer
Sector
Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, P.le Aldo Moro
5, 00185 Rome, Italy
SSD BIO/14 Pharmacology
Education and training 1971, Degree in Medicine and Surgery (full score), University of Napoli, Italy
1971-1973 Fellowship at the Institute of Pharmacology, University of Bari (Italy)
1976 Specialization in Hygiene and Preventive Medicine, University of Bari, Italy
Personal skills and
competences
Mother tongue(s)
Italian
Other language(s)
English
Self-assessment
Understanding
Listening
European level (*)
C2
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Surname(s) First name(s)
Italian
Speaking
Reading
C2
Italian
Spoken interaction
C2
Italian
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© European Union, 2004-2010 24082010
Writing
Spoken production
C2
Italian
C2
Italian
C1
English
C1
English
C1
English
C1
English
C1
English
(*) Common European Framework of Reference for Languages
Additional information Teaching activities:
Course of Chemotherapy, Faculty of Medicine, University of Bari (1975-1980)
Course of Pharmacology, Faculty of Medicine, University of Bari (1980-1982)
Course of Pharmacology (Associate Professor), Faculty of Medicine, University of Bari (1982-1985)
Course of Pharmacology (Full Professor), Faculty of Medicine, University of Bari (1986-2001)
Courses of Pharmacology and Toxicology in various Schools for Medical Specializations, Faculty of
Medicine, University of Bari (1986-2001)
Coordinator f the PhD program “Clinical Pharmacology and Medical Therapy” University of Bari (19882001)
Course of Toxicology, School for Medical Specialization in Pharmacology, Faculty of Medicine,
University of Bari (1989-2001)
Course of Pharmacology and Pharmacotherapy, Master Course in Medicinal Chemistry, Faculty of
Pharmacy, University of Rome “La Sapienza” (2001-2003)
Coordinator of the PhD program in Toxicology and Pharmacology (previously Pharmacology,
Pharmacognosy and Toxicology), University of Rome “La Sapienza” (2001-present)
Course of Pharmacology, Master Course in Environmental Toxicology, Faculty of Pharmacy,
University of Rome “La Sapienza” (2003-2004)
Course of Pharmacology II, Master Course in Pharmaceutical Biotechnology, Faculty of Pharmacy,
University of Rome “La Sapienza” (2003-2004)
Course of Pharmacology and Pharmacotherapy I and II, Master Course in Medicinal Chemistry,
Faculty of Pharmacy, University of Rome “La Sapienza” (2004-2005)
Course of Pharmacology and Pharmacotherapy, Master Course in Medicinal Chemistry, Faculty of
Pharmacy and Medicine, University of Rome “La Sapienza” (2005-present)
Collaborations:
Institut fur Toxikologie der Universitat Zurich, Schweiz (Prof. G. Zbinden – Dr. J. Elsner)
Dept. of Environmental Health Sciences, Division of Toxicology, Johns Hopkins University, Baltimore,
USA (Prof. Z. Annau)
Dept. of Zoology, King's College, University of London, England (Dr. G.D. Sales)
Dept. of Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA (Prof. R.J.
Barfield)
Dept. of Experimental Psychology, University of Cambridge, London, England (Prof. T. W. Robbins)
Dept. of Neurobiology, Babraham Institute, Cambridge, England (Dr. K. Kendrick)
Dept. of Pharmacology, University of Nottingham, England (Prof. C.A. Marsden)
Laboratoire de Toxicologie et d’Hygiene Appliquée, Université Bordeaux II, France (Prof. E.E. Creppy)
Dept. of Pharmacology, University of California, Irvine (Prof. D. Piomelli)
Dept. of Neurobiology & Behavior, University of California, Irvine (Prof. J. McGaugh)
Department of Pharmacology and Anatomy, Rudolf Magnus Institute, Utrecht, the Netherlands (Prof.
L.J.M.J. Vanderschuren)
Department of Psychiatry, McGill University, Montreal, Canada (Prof. G. Gobbi)
Receiving
Every day (Monday-Friday) upon appointment fixed by email
Annexes
Scientific Publication
Selected 30 publications among those published in the last 15 years (IF=impact factor)
1. TRABACE L, ZOTTI M, MORGESE MG, TUCCI P, COLAIANNA M, SCHIAVONE S, AVATO P,
CUOMO V. Estrous cycle affects the neurochemical and neurobehavioral profile of carvacroltreated female rats. Toxicol Appl Pharmacol 2011, 255(2):169-75
(IF 3.993)
2. COLAIANNA M, TUCCI P, ZOTTI M, MORGESE MG, SCHIAVONE S, GOVONI S, CUOMO V,
TRABACE L, Soluble B-Amyloid1-42: a critical player in producing behavioural and biochemical
changes evoking depressive-related state?, Br J Pharmacol 2010, 159(8):1704-15
(IF
4.925)
3. GAETANI S, FU J, CASSANO T, DIPASQUALE P, ROMANO A, RIGHETTI L, CIANCI S,
LACONCA L, GIANNINI E, SCACCIANOCE S, MAIRESSE J, CUOMO V, PIOMELLI D, The fatinduced satiety factor OEA suppresses feeding through central release of oxytocin, J Neurosci
2010, 30(24):8096–8101,
(IF 7.271)
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4. SORCE S, SCHIAVONE S, TUCCI P, COLAIANNA M, JAQUET V, CUOMO V, DUBOIS-DAUPHIN
M, TRABACE L, KRAUSE KH, The NADPH oxidase NOX2 controls glutamate release: a novel
mechanism involved in psychosis-like ketamine responses, J Neurosci 2010, 30(34):11317-25
(IF 7.271)
5. CAMPOLONGO P, ROOZENDAAL B, TREZZA V, CUOMO V, ASTARITA G, FU J, MCGAUGH JL,
PIOMELLI D, The fat-induced satiety factor OEA enhances memory consolidation. Proc Natl Acad
Sci U S A 2009, 106(19): 8027-31
(IF 9.771)
6. CAMPOLONGO P, TREZZA V, PALMERY M, TRABACE L, CUOMO V Developmental exposure to
cannabinoids causes subtle and enduring neurofunctional alterations, Int Rev Neurobiol 2009
85:117-33 (IF 4.017)
7. GAETANI S, DIPASQUALE P, ROMANO A, RIGHETTI L, CASSANO T, PIOMELLI D, CUOMO V
The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs. Int Rev
Neurobiol 2009, 85:57-72
(IF 4.017)
8. CAMPOLONGO P, ROOZENDAAL B, TREZZA V, HAUER D, SCHELLING G, MCGAUGH JL,
CUOMO V. Endocannabinoids in the rat basolateral amygdala enhance memory consolidation:
involvement of the glucocorticoid system. Proc Natl Acad Sci USA 2009, 106(12):4888-93 (IF
9.771)
9. SCHWARTZ GJ, FU J, ASTARITA G, XIAOSONG L, GAETANI S, CAMPOLONGO P, CUOMO V,
PIOMELLI D The lipid messenger OEA links dietary fat intake to satiety. Cell Metab 2008, 8(4):2818
(IF 18.207)
10. TREZZA V, CAMPOLONGO P, CASSANO T, MACHEDA T, DIPASQUALE P, CARRATÙ MR,
GAETANI S, CUOMO V Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the
emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats.
Psychopharmacology 2008, 198(4):529-37
(IF 3.817)
11. CASTALDO P, MAGI S, GAETANI S, CASSANO T, FERRARO L, ANTONELLI T, AMOROSO S,
CUOMO V. Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases
glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in
rat frontal cerebral cortex. Neuropharmacology 2007, 53(3):369-78 (IF 4.677)
12. GOBBI G, BAMBICO FR, MANGIERI R, BORTOLATO M, CAMPOLONGO P, SOLINAS M,
CASSANO T, MORGESE MG, DEBONNEL G, DURANTI A, TONTINI A, TARZIA G, MOR M,
TREZZA V, GOLDBERG SR, CUOMO V, PIOMELLI D, Antidepressant-like activity and modulation
of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci
USA 2005, 102(51):18620-5
(IF 9.771)
13. CAMPOLONGO P, TREZZA V, CASSANO T, GAETANI S, MORGESE MG, UBALDI M,
SOVERCHIA L, ANTONELLI T, FERRARO L, MASSI M, CICCOCIOPPO R, CUOMO V. Perinatal
exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with
alteration of cortical gene expression and neurotransmission in rats. Addict Biol 2007, 12(3-4): 48595
(IF 4.152)
14. BORTOLATO M, CAMPOLONGO P, MANGIERI RA, SCATTONI ML, FRAU R, TREZZA V, LA
RANA G, RUSSO R, CALIGNANO A, GESSA GL, CUOMO V, PIOMELLI D. Anxiolytic-like
properties of anandamide transport inhibitor AM404. Neuropsychopharmacology 2006,
31(12):2652-9
(IF 6.685)
15. ANTONELLI T, TOMASINI MC, TATTOLI M, CASSANO T, TANGANELLI S, FINETTI S, MAZZONI
E, TRABACE L, STEARDO L, CUOMO V, FERRARO L Prenatal exposure to the CB1 receptor
agonist WIN 55,212-2 causes learning disruption associated with impaired cortical NMDA receptor
function and emotional reactivity changes in rat offspring. Cereb Cortex 2005, 15(12):2013-20
(IF 6.844)
16. COSTA LG, STEARDO L, CUOMO V Structural effects and neurofunctional sequelae of
developmental exposure to psychotherapeutic drugs: experimental and clinical aspects. Pharmacol
Rev 2004, 56(1):103-47
(IF 18.861)
17. SARTIANI L, CERBAI E, LONARDO G, DE PAOLI P, TATTOLI M, CAGIANO R, CARRATU’ MR,
CUOMO V, MUGELLI A. Prenatal exposure to carbon monoxide affects postnatal cellular
electrophysiological maturation of the rat heart: a potential substrate for arrhythmogenesis in
infancy. Circulation 2004, 109(3):419-23 (IF 14.429)
18. KATHURIA S, GAETANI S, FEGLEY D, VALINO F, DURANTI A, TONTINI A, MOR M, TARZIA G,
LA RANA G, CALIGNANO A, GIUSTINO A, TATTOLI M, PALMERY M, CUOMO V, PIOMELLI D,
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Modulation of anxiety through blockade of anandamide hydrolysis, Nat Med 2003, 9(1):76-81
(IF 25.430)
19. MEREU G., FÀ M., FERRARO L., CAGIANO R., ANTONELLI T., TATTOLI M., GHIGLIERI V.,
TANGANELLI S., GESSA G.L., CUOMO V. Prenatal exposure to a cannabinoid agonist produces
memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release,
Proc Natl Acad Sci USA 2003, 100(8):4915-20 (IF 9.771)
20. GAETANI S, CUOMO V, PIOMELLI D, Anandamide hydrolysis: a new target for anti-anxiety drugs?
Trends Mol Med 2003, 9(11):474-8
(IF 10.308)
21. TRABACE L, CASSANO T, LOVERRE A, STEARDO L, CUOMO V, CHF2819: Pharmacological
profile of a novel acetylcholinesterase inhibitor, CNS Drug Rev 2002, 8(1):53-69 (IF 3.492)
22. CAGIANO R, CASSANO T, COLUCCIA A, GAETANI S, GIUSTINO A, STEARDO L, TATTOLI M,
TRABACE L, CUOMO V, Genetic factors involved in the effects of developmental low-level alcohol
induced behavioral alterations in rats, Neuropsychopharmacology 2002, 26(2):191-203 (IF
6.685)
23. VACCARI A, RUIU S, SABA P, FA’ M, CAGIANO R, COLUCCIA A, MEREU G, STEARDO L,
TATTOLI M, TRABACE L, CUOMO V, Prenatal low level exposure to CO alters postnatal
development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats, Int J
Neuropsychopharmacol 2001, 4(3):219-222
(IF 4.699)
24. TATTOLI M, CAGIANO R, GAETANI S, GHIGLIERI V, GIUSTINO A, MEREU G, TRABACE L,
CUOMO V, Neurofunctional effects of developmental alcohol exposure in alcohol-preferring and
alcohol-nonpreferring rats, Neuropsychopharmacology 2001, 24(6):691-705
(IF 6.685)
25. MEREU G, CAMMALLERI M, FA’ M, FRANCESCONI W, SABA PL, TATTOLI M, TRABACE L,
VACCARI A, CUOMO V, Prenatal exposure to a low concentration of carbon monoxide disrupts
hippocampal long-term potentiation in rat offspring, J Pharmacol Exp Ther 2000, 294(2):728-34
(IF 4.017)
26. STEARDO L, MONTELEONE P, TRABACE L, CANNIZZARO C, MAJ M, CUOMO V, Serotonergic
modulation of rat pineal gland activity: in vivo evidence for a 5-HT2C receptor involvement, J
Pharmacol Exp Ther 2000, 295(1):266-73
(IF 4.017)
27. TRABACE L, CASSANO T, STEARDO L, PIETRA C, VILLETTI G, KENDRICK KM, CUOMO V,
Biochemical and neurobehavioral profile of CHF2819, a novel orally active acethylcholinesterase
inhibitor for Alzheimer’s disease, J Pharmacol Exp Ther 2000, 294(1):187-94 (IF 4.017)
28. CAGIANO R, ANCONA D, CASSANO T, TATTOLI M, TRABACE L, CUOMO V, Effects of prenatal
exposure to low concentrations of carbon monoxide on sexual behaviour and mesolimbic
dopaminergic function in rat offspring, Br J Pharmacol 1998,125(4):909-15
(IF 4.925)
29. STEARDO L, MONTELEONE P, d’ISTRIA M, SERINO I, MAJ M, CUOMO V,  receptor modulation
of noradrenergic-stimulated pineal melatonin biosynthesis in rats, J Neurochem 1996, 67, 287-293
(IF 4.337)
30. CUOMO V, DE SALVIA MA, PETRUZZI S, ALLEVA E, Appropriate endpoints for the
characterization of behavioral changes in developmental toxicology, Environ Health Perspec 1996,
104, 307-315 (invited review). (IF 6.087)
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Selected Textbooks (Chapters, etc.)
ROSSI F, CUOMO V, RICCARDI C “Farmacologia. Principi di base e applicazioni Terapeutiche” Ed.
Minerva Medica, Torino, seconda edizione 2011
CUOMO V, STEARDO L, Assunzione di sostanze di abuso durante la gestazione, MEDICINA
CLINICA. Basi Biologiche Diagnostica Terapia, C.G. Ed. Med. Scient., Torino, 2003, 4(cap. XXIX), pp.
1-20.
COURT J, CUOMO V, ERIKSSON P, PERRY E, PICKLES A, RAY D, RODIER P, STANTON M,
TAYLOR, VARGHA-KHADEM F, Perinatal developmental neurotoxicity, Medical Research Concil,
Institute for Environment and Health Publish., Report 4, Leichester, UK, pp. 1-84, 1996.
ZBINDEN G, CUOMO V, RACAGNI G, WEISS B Application of Behavioural Pharmacology in
Toxicology", (Eds.), Raven Press, N.Y., pp. 161-172, 1983
RACAGNI G, MOCCHETTI I, DE ANGELIS L, BARALDI M, CUOMO V, In vivo effects of typical and
atypical antidepressants on brain noradrenergic system: behavioural correlations, Adv. Biochem.
Psychopharmacol., Raven Press, N.Y., 31, 185-197, 1982.
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© European Union, 2004-2010 24082010