CV Bonassi
Transcript
CV Bonassi
CURRICULUM VITAE Name: Birth date: Stefano BONASSI January, 3, 1956 Nationality: Italian Family: Married with Angela Calvi since 1983 with four children Position: Head, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Pisana Via di Val Cannuta, 247 00166 Rome Tel. +39- 06-52253418; Fax +39-06-52255668 [email protected] Home address: Piazza Vittorio Veneto 6/6, I-16149 Genova - Italy Tel. +390-10-418522 Education and specialty training: Doctor in Biological Sciences - University of Genova (1981) Specialist in Medical Statistics and Epidemiology - University of Pavia (1987) In 2014 received from the Italian Ministry of Research the National Academic Qualification for full Professor of Hygiene and Epidemiology (06/M1). Research and professional experience IRCCS San Raffaele Pisana – Rome. Head, Unit of Clinical and Molecular Epidemiology (2009-to.present) National Cancer Research Institute – Genova. Junior research fellow (1981-1986) Junior scientist (1987-1989) Senior Scientist (1990-2000) Head, Unit of Molecular Epidemiology (2000-2009) University of Genoa – Genova. Adjunct Professor of Molecular Epidemiology (2006-to present) Istituto Giannina Gaslini (Children Hospital) – Genova, Italy Consultant (1988-1989). 1 Italian League against Cancer, Consultant (1984). National Institute for Occupational Safety and Health (NIOSH) - Cincinnati, OH, USA. Visiting Scientist (1985). - Faculty for doctoral program in nutrition at the San Raffaele University in Rome, Italy - Faculty for PhD and Masters programs in human genetics of the Universidad Autonoma de Barcelona, Barcelona, Spain; - M2E2 Master program Intenational courses of Molecular Epidemiology of Chronic diseases at the Maastricht University, the Netherlands; - Master in Epidemiology, Universita’ Cattolica del Sacro Cuore, Roma, Italy. Consultant (Epidemiologist/Statistician) for Janssen, Novartis, Menarini, Indena, Schwabe National and International research grants (after 2000) Associate investigator in research grants awarded by: the Italian Ministry of Health, Italian Ministry for the Environment, Italian Association for Research on Cancer, Italian Research Council, Liguria Region. Italian Association for Research on Cancer (1998-2000) 105.000 €. Italian Association for Research on Cancer (2000-2002) 70.000 €. Italian Association for Research on Cancer (2006-2008) 20.000 €. Italian Association for Research on Cancer (2011-2013) 210.000 €. Italian Association for Research on Cancer (2010-2014) 25.000 €. INAIL Valutazione di biomarker di instabilità genetica, danno ossidativo e lesioni precoci in sangue, cellule esfoliate dalla mucosa boccale ed esalato bronchiale di lavoratori a rischioamianto’ (2011-2013) 190.000 € INAIL Studio caso – controllo sui fattori di rischio familiari e diagnosi precoce della malattia di Parkinson (2011-2013) 30.000 € Ministero della salute Determination if lack of variabilità in cardiac r-r interval on EKG predicts the development of the classic motor features of Parkinson’s disease (2011-2013) 30.000 € Buzzi Foundation – Casale M. ‘Chemoprevention of environmentally induced genetic instability: a randomized trial of NAC vs. placebo in a group of retired workers exposed to asbestos. As Primary contractor (2008-2011) 150.000 €. 2 He has received support also from the NATO Life Science and Technology program, as Director of Advanced Research Workshops (Lyon, 2001) and from the University of California-Berkeley (2002). Italian Space Agency Project: From Molecules to Man: WP ‘Genetic monitoring of astronauts’ (2006-2008) 336.723 € Italian Ministry of Health ‘Multidisciplinary approach and phisical training in patients at high risk of adverse cardiovascular events " (2006-2007) 24.000 € Italian Ministry of Health ‘Identification of tumor biomarkers through a biology-driven integrated approach " (2007-2009) 38.000 € AIFA Therapeutic equivalence, bioequivalence and pharmacokinetic profile of the “generic” levodopa/carbidopa preparation (HEXAL SpA) compared to the “originator” (Sinemet®), in patients with fluctuating Parkinson’s disease. (2010-2012) 25.000 € AIFA Effect of an integrated e-learning intervention, focused on Comprehensive Geriatric Assessment to improve the quality of drug prescribing in hospitalized elderly patients. (2009-2011) come SIGOT (20.000 € + 40.000 €) AIFA Studio valutativo su efficacia di un intervento di formazione finalizzato al miglioramento della prescrizione farmacologica in pazienti anziani in politerapia. (2012-2014) (as WP leader) 720.000 € AIFA Pharmacological treatment in the elderly patient affected by cardiovascular diseases and other chronic comorbidities: inappropriate prescribing and outcome evaluation among institutionalized and community-dwelling elderly (2012-2014) 90.000 € CCM Assistenza residenziale per gli anziani: costruzione e validazione di un sistema di sorveglianza quality ed equity oriented (2010-2011) 50.000 € Fondazione FORST Effectiveness of thermal water nasal inhalation and irrigation in rhynopharyngitis and sinusitis (2013-2014) 90.000 € Fondazione Umberto veronesi. Micronucleus frequency in exfoliated buccal cells as a biomarker of DNA aging and risk for age-related diseases. (2013-2014) 25.000 € European Community partnerships BIOMED2 (Interaction of genetic and occupational factors) Concerted Action: "Assessments of Predictive Value for Cancer of Cytogenetic Biomarkers Used in Health Surveillance of Occupational Exposed Workers" as Primary Contractor (1995-2001) (50.000 €) 3 Fifth Framework Program (Quality of Life and Management of Living Resources) ‘Cytogenetic biomarkers and human cancer risk’ as Primary Contractor (2001-2005) (240.000 €) Extension to NAS (Newly Applicant States) of the program Quality of Life and Management of Living Resources) ‘Cytogenetic biomarkers and human cancer risk’ as Primary Contractor (2003-2005) (25.000 €) Fifth Framework Program (Quality of Life and Management of living Resources) Key action 4: Environment and Health ‘European Network on Children’s susceptibility and exposure to environmental genotoxicants’ CHILDRENGENONETWORK as Primary Contractor (20032005) (30.000 €) (FP7 - 2007-2013) Framework Programme for Research and Technological Development SCRIPT Supervised Care and Rehabilitation involving personal tele-robotics. As Associate researcher (2011-2014) Objective 2013.5.1: Personalised Health, active ageing and independent living: eWall for Active Long Living (eWALL) as Work package Leader (2013-2015)( 576.584 €) Teacher of Epidemiological Methods in courses forPhD students and young investigators (after 2000): Institute for Scientific Interchange, Turin (1999, 2000, 2001, 2002, 2003) ‘Ettore Majorana’ International Center for Scientific Culture, Erice (2000) Italian Association of Epidemiology, Rome, (2000) Environmental Mutagen Society, S.Diego, USA (2001) Corso Avanzato di Radioprotezione Medica, INFN. Bressanone, (1999, 2001) Environmental Mutagen Society, Anchorage, USA (2002) The Alexander Hollander Course, Kracow, Poland (2002) UC Berkeley - IARC Courses on Molecular Epidemiology, Berkeley, USA (2002) Faculté de Mèdecine, Marseille, France (2003) Universidad de los andes, Bogota’, Colombia (2004) Environmental Muragen Society, San Francisco, USA (2005) 2nd Course of the International School of Bioelectromagnetics “Alessandro Chiabrera” on Electromagnetic Fields and Genotoxicity. Erice, Italy (2005) Universidad de los andes, Bogota’, Colombia (2006) The Alexander Hollander Course, Valparaiso, Chile (2006) Centro de Protección e Higiene de las Radiaciones, La Habana, Cuba (2007) Alexander Hollaender course on genetic toxicology, Kolkata, India (2008) Marie Curie Training Courses, University of Kuopio, Finland (2008) The Alexander Hollaender Course, Astana (Kazchstan) (2009) Universidad de LaPaz, LaPaz (Bolivia) February 2011 4 Porto University, Porto, Portugal. 15-20 May 2011 Maastricht University, Maastricht. Netherlands, 23-27 April 2012 UCSC, Rome, 3-5 May 2012 Maastricht University, Maastricht. Netherlands, 4-7 April 2013 UCSC, Rome, 24-25 May 2013 Alexander Hollander course, Asumption, Paraguay, 8-9 November 2013 Dr. Bonassi has supervised many specialization theses and postgraduate research projects at the University of Genoa, and was part of the jury in PhD theses defense at the universities of Marseille, Brussels, Copenhagen, and Porto. Professional Society Membership Italian Association of Epidemiology (AIE); Italian Society of Cancer Research (SIC); American Association for Cancer Research (AACR); European Environmental Mutagen Society (EEMS), SIGOT US Environmental Mutagen Society (EMS) – Councilor (2001-2005) Italian Environmental Mutagen Society (SIMA) – Councilor (2007-2009) From 2009 to 2013 Dr. Bonassi has served as President of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMS) an international association with 6.000 members all over the world (www.IAEMS.net) Reviewer of the following journals: International Journal of Cancer; Mutation Research; Reviews in Mutation Research; European Journal of Public Health; Epidemiologia & Prevenzione (in Italian); Lancet; Alcoholism Clinical and Experimental Research; Mutagenesis; Cancer Epidemiology, Biomarkers & Prevention; Carcinogenesis; The annals of Occupational Hygiene; Indian Journal of Cancer; Cancer research; Toxicology and Applied Pharmacology; Genetics and Molecular Biology; Genes, Chromosomes and Cancer; Chromosome Research; Journal National Cancer Institute; Diabetes Research and Clinical Practice; The Journal of Clinical Endocrinology & Metabolism; Circulation, Maturitas. Dr. Stefano Bonassi is member of the editorial board of the following journals: 1. International Journal of Hygiene and Environmental Health, 2. Environmental & Molecular Mutagenesis, 3. Mutagenesis, 4. Cancer Epidemiology (former Cancer Detection and Prevention), 5. Revista Internacional de Contaminación Ambiental 6. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 5 He has been guest editor of special issues published by the journal Mutation Research and Environmental and Molecular Mutagenesis. Among the other references, Dr. Bonassi has been member of the Ethics committee of the San Paolo Hospital of Savona, Italy from 2000 to 2009 and is currently the biostatistician member of the IRCCS San Raffaele Pisana ethics committee. He has been designated by the WHO/IPCS as a member of the Task Group of European Experts on Biomarkers in Risk Assessment, and he is in the board of project reviewers for the Italian Minister of Education, University and Scientific research (MIUR), for the Minister of Health, for the Piedmont Region (CIPE), for the Minister of Health of Colombia (Colciencias), Qatar (QNRF), and Ecuador (Senescyt), France (CNRS). He has been scientific advisor for European organizations such as ECETOC (European Centre for Ecotoxicology and Toxicology of Chemicals), pharmaceutical companies, euch as NOVARTIS; and charities such as Cancer Research UK. Dr. Bonassi is included as a national expert in the EU Data Project of the Joint Programming Initiative “More Years, better Lives”. In his private life Dr. Bonassi is the president of a charity which promotes and support children fostering (Il Nodo www.il-nodo.it) 6 After a first period as occupational and environmental epidemiologist his main scientific interest soon shifted toward molecular epidemiology and the use of biomarkers in human population studies an dclinical trials. In particular he was actively involved in assessing the role of chromosomal damage in the early stages of carcinogenesis and the possible use of biomarkers of DNA damage to predict cancer occurrence. Other topics of interest are the development of epidemiological and statistical methods in population studies, and the validation of alternative sources of tissue for biomarkers. Coordinator of the Italian side of the European Study Group on Cytogenetic Biomarkers and Health (ESCH) and member of the steering committee of the International Collaborative Project on Micronucleus Frequency in Human Populations (HUMN). He is focused his research on the use of high throughput tecniques in population studies and in clinical series to assess gene expression profile and genotype to identify subjects at risk or to validate diagnostic/prognostic biomarker. After working for several years as the chief of the Unit of Molecular Epidemiology at the National Cancer Reseacrh Institute in Genoa he moved to Rome, to lead the unit of Clinical and Molecular Epidemiology, with a commitment oriented mostly to clinical research and an interest extended to cardiovascular diseases, neurodegenerative disorders, and physical rehabilitation. In his new appointment he has participated to clinical researches in different rehabilitation settings, e.g., cardiologic, respiratory, and neurological. He hast started two extensive platforms of COPD and schyzofrenic patients to generate studies of systems medicine. These studies include a structured tissues biorepository. Finally, he is involved in researches in geriatrics, mostly addressing issues dealing with the appropriateness of drug prescription in elderly, but also several other issues involved with aging and frailty. This year he started together with Prof. Andrew Collins the ComNet project, an international collaborative project on the Comet assay (DNA damage and repair) involving more than 100 laboratories all over the world. 7 Invited speaker to the following meetings (since 2000): 7th International Conference on Mechanisms of Antimutagenesis & Anticarcinogenesis. Grand Rapids, Michigan, USA. 23-27 September 2000. 39th Annual Meeting of European Enviromental Mutagen Society. Budapest, Hungary. 22-26 August, 2000. XXIV Riunione scientifica annuale. Associazione Italiana di Epidemiologia. Rome, Italy. 22-24 October, 2000. 32th Annual Meeting of the Environmental Mutagen Society. San Diego, USA. 16-21 March, 2001. 8th International Conference of Environmental Mutagen Societies Shizuoka, Japan 21-26 October, 2001 Cancer Research Methods Workshop – NIOSH Washington, USA, 8-9 May, 2002 Molecular Epidemiology in Preventive medicine: Achievements and new challenges. Kracow, Poland, 20-22 June 2002 2nd INTAS Meeting Capri, Italy, 11-13 June 2002 Molecular and Genetic Epidemiology of Cancer (AACR Special meetings) Kailua-Kona, USA, 18-23 January 2003 Workshop on advances in Human Research, Exposure and Risk Assessment related to Reproductive and Developmental Effects. Prague, Czech Republic, 17-20 March, 2003 4th International Conference on Environmental Mutagenesis in Human Populations Florianopolis, SC – Brazil, 4-8 May, 2003. International meeting on Chromosomal aberration Essen, Germany, 10-13 September, 2003 Prevention des cancer professionnels Europole de l’arbois, Marseille – France, 2-3 December 2003 ICT X Satellite meeting in Molecular Epidemiology Porvoo, Finland, 8-10 July, 2004 8 International Symposium on Preventive Oncology Nice, France, 8-11 February, 2004. III Congreso Internacional de Genetica Barranquilla, Colombia, 18-20 February 2004 9° International Conference on Environmental Mutagens San Francisco, USA, 4-6 September 2005. 5th European Cytogenetics Conference Madrid, Spain, 4-7 June 2005. 7th International Conference on DNA Repair St. Andrews, UK, 5-6 June 2005. 36th European Environmental Mutagens Society Prague, Czech Republic, 2-6 July 2006 Turkish Society of Toxicology Antalya, Turkey, 1-5 November 2006 Minesseminarium For Lars Hagmar Lund, Sweden, 26th November 2006 Belgian Society for Toxicology and Ecotoxicology Leuven, Belgium, 1st December 2006 5th International conference on Environmental Mutagens in Human Populations Antalya, Turkey, 20-24 May 2007 Risk-RAD Workshop on Chromosome aberrations and telomeres in carcinogenesis Paris, France, 7-8 June 2007 VII Congreso LatinoAmericano de Mutagenesis, Carcinogenesis, y Teratogenesis Cartagena, Colombia, 29-31 August 2007 The 8th International Symposium on Chromosome Aberrations Awaji Island, Hyogo, Japan, 4-6 October 2007 3rd Asia-Pacific Nutrigenomics conference: Diet-gene interaction in human health and disease Melbourne, Australia, 6-9 May 2008 14th Alexander Hollaender course. Workshop on arsenic exposure assessment 9 Kolkata, India 10-12 December 2008 3rd Meeting of ECNIS Network of Excellence. Role of gender in chromosome damage Bruxelles 17 March 2009 Annual Meeting of Spaniish EMS Barcelona, 29 June- 1 July 2009 Dutch Society of Toxicology. 30th Annual meeting The future starts now – innovative toxicity testing Veldhoven, The Netherlands 18-19 June 2009 9th International meeting onChromosomal aberrations (ISCA) Rheinfels Castle, Germany 11-12 July 2009 15th Alexander Hollaender course. Genome environment interactions and genetic toxicology Astana, Kazakhstan 23-26 September 2009 Brazilian Society of Genotoxicology Ouro Preto (Mingas gerais), Brazil 9-15 November 2009 AQUATRAIN FINAL conference Orleans, Paris. 7-8 July 2010 ICMAA and Nutrigenomics 2010 Guaruja’ (Brazil) 25-29 Septmber 2010 2nd AEMS Bangkok (Thailand) 14-18 December 2010 Workshop on: Risk Perception of Nanotechnologies and Early Warning Systems. Berlin (Germany) 24-25 May 2011 International Societ of Geriatric Oncology Paris (France) 3-5 November 2011 Workshop on Nanotechnology (NANOLINEN Project) Paris (France) 14-15 December 2011 Workshop: Exposure to nanoparticles in human populations: Immune system biomarkers in vitro and in vivo St.Christoph/Arlberg (Austria), 26 - 29 february, 2012 VIth International Conference on Environmental Mutagens in Human Populations. 10 Doha, Qatar, 25-29 March 2012 NanoLINEN Workshop Antalya, Turkey, 26-29 April 2012 32nd annual meeting of the French Society of Mutragenesis and Genotoxicology Rennes, France, 24-25 May 2012 2nd AAEMS conference. Hangtzou, China, 19-23 October 2012 International Conference of Toxicology Seoul, Korea, 1-4 July 2013 XI ICEM Foz de Iguassu, Brazil, 1-4 November 2013 31th European Respiratory Society Munich, 1-4 September 2014 Seminars (since 2000): Le aberrazioni cromosomiche come test predittivo nella cancerogenesi. Laboratori Nazionali di Frascati. Frascati, Italy. 18 January 2000. Validation of biomarkers as early predictors of cancer MSKCC, New York, USA. 7 May, 2002 Chromosomomal Aberration and risk of cancer in humans RERF, Hiroshima, Japan. 22 March, 2004 Environmental and Molecular Epidemiology of Cancer Universidad de los Andes, Bogota’, Colombia, 16 February 2004 Molecular Epidemiology of Cancer Colciencias, Bogota’, Colombia, 24 May 2006 11 Game theory for the analysis of data from high throughput assays Vrje University, Bruxelles, Belgium 27 November 2008 Molecular Epidemiology Sant Ander University, La Paz,, Bolivia, April 2011. 12 Publications Papers published by Stefano Bonassi have been cited 10900 times with a h index = 52 (Scholar). 1: Massimo L, Rossoni N, Mattei F, Bonassi S, Caprino D. Needs and expectations of adolescent in-patients: the experience of Gaslini Children's Hospital. Int J Adolesc Med Health. 2015 Jan 23. pii: /j/ijamh.ahead-of-print/ijamh-2014-0070/ijamh-2014-0070.xml. doi: 10.1515/ijamh-2014-0070. [Epub ahead of print] PubMed PMID: 25720045. 2: Sánchez-Flores M, Pásaro E, Bonassi S, Laffon B, Valdiglesias V. γH2AX assay as DNA damage biomarker for human population studies: defining experimental conditions. Toxicol Sci. 2015 Apr;144(2):406-13. doi: 10.1093/toxsci/kfv011. Epub 2015 Jan 22. PubMed PMID: 25616596. 3: Neri M, Frustaci A, Milic M, Valdiglesias V, Fini M, Bonassi S, Barbanti P. A meta-analysis of biomarkers related to oxidative stress and nitric oxide pathway in migraine. Cephalalgia. 2015 Jan 8. pii: 0333102414564888. [Epub ahead of print] PubMed PMID: 25573894. 4: Neri M, Milazzo D, Ugolini D, Milic M, Campolongo A, Pasqualetti P, Bonassi S. Worldwide interest in the comet assay: a bibliometric study. Mutagenesis. 2015 Jan;30(1):155-63. doi: 10.1093/mutage/geu061. PubMed PMID: 25527738. 5: Ugolini D, Bonassi S, Cristaudo A, Leoncini G, Ratto GB, Neri M. Temporal trend, geographic distribution, and publication quality in asbestos research. Environ Sci Pollut Res Int. 2015 May;22(9):6957-67. doi: 10.1007/s11356-014-3925-1. Epub 2014 Dec 6. PubMed PMID: 25475619. 6: Gison A, Rizza F, Bonassi S, Dall'Armi V, Lisi S, Giaquinto S. The sense-of-coherence predicts health-related quality of life and emotional distress but not disability in Parkinson's disease. BMC Neurol. 2014 Oct 10;14:193. doi: 10.1186/s12883-014-0193-0. PubMed PMID: 25304029; PubMed Central PMCID: PMC4197289. 7: Marzetti E, Lorenzi M, Antocicco M, Bonassi S, Celi M, Mastropaolo S, Settanni S, Valdiglesias V, Landi F, Bernabei R, Onder G. Shorter telomeres in peripheral blood mononuclear cells from older persons with sarcopenia: results from an exploratory study. Front Aging Neurosci. 2014 Aug 28;6:233. doi: 10.3389/fnagi.2014.00233. eCollection 2014. PubMed PMID: 25221511; PubMed Central PMCID: PMC4147848. 8: Aleksovska K, Leoncini E, Bonassi S, Cesario A, Boccia S, Frustaci A. 13 Systematic review and meta-analysis of circulating S100B blood levels in schizophrenia. PLoS One. 2014 Sep 9;9(9):e106342. doi: 10.1371/journal.pone.0106342. eCollection 2014. Review. PubMed PMID: 25202915; PubMed Central PMCID: PMC4159239. 9: Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V, Cazzola M, Dall'Armi V, Daraselia N, Ros LD, Bufalo AD, Ducci G, Ferri L, Fini M, Fossati C, Gensini G, Granone PM, Kinross J, Lauro D, Cascio GL, Lococo F, Lococo A, Maier D, Marcus F, Margaritora S, Marra C, Minati G, Neri M, Pasqua F, Pison C, Pristipino C, Roca J, Rosano G, Rossini PM, Russo P, Salinaro G, Shenhar S, Soreq H, Sterk PJ, Stocchi F, Torti M, Volterrani M, Wouters EF, Frustaci A, Bonassi S. A systems medicine clinical platform for understanding and managing non- communicable diseases. Curr Pharm Des. 2014;20(38):5945-56. PubMed PMID: 24641232. 10: Costa C, García-Lestón J, Costa S, Coelho P, Silva S, Pingarilho M, Valdiglesias V, Mattei F, Dall'Armi V, Bonassi S, Laffon B, Snawder J, Teixeira JP. Is organic farming safer to farmers' health? A comparison between organic and traditional farming. Toxicol Lett. 2014 Oct 15;230(2):166-76. doi: 10.1016/j.toxlet.2014.02.011. Epub 2014 Feb 24. PubMed PMID: 24576785. 11: Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Fuchs D, Geisler S, Dall'Armi V, Zoffoli R, Bonassi S, Pásaro E, Laffon B, Teixeira JP. Immunological alterations in individuals exposed to metal(loid)s in the Panasqueira mining area, Central Portugal. Sci Total Environ. 2014 Mar 15;475:1-7. doi: 10.1016/j.scitotenv.2013.12.093. Epub 2014 Jan 11. PubMed PMID: 24419281. 12: Kirsch-Volders M, Bonassi S, Knasmueller S, Holland N, Bolognesi C, Fenech MF. Commentary: critical questions, misconceptions and a road map for improving the use of the lymphocyte cytokinesis-block micronucleus assay for in vivo biomonitoring of human exposure to genotoxic chemicals-a HUMN project perspective. Mutat Res Rev Mutat Res. 2014 Jan-Mar;759:49-58. doi: 10.1016/j.mrrev.2013.12.001. Epub 2014 Jan 8. PubMed PMID: 24412600. 13: Franchi C, Mari D, Tettamanti M, Pasina L, Djade CD, Mannucci PM, Onder G, Bernabei R, Gussoni G, Bonassi S, Nobili A; ELICADHE Investigators. E-learning to improve the drug prescribing in the hospitalized elderly patients: the ELICADHE feasibility pilot study. Aging Clin Exp Res. 2014 Aug;26(4):435-43. doi: 10.1007/s40520-013-0187-6. Epub 2013 Dec 17. PubMed PMID: 24343853. 14: Posteraro B, Persiani R, Dall'Armi V, Biondi A, Arzani D, Sicoli F, Bonassi S, D'Ugo D, Ricciardi W, Boccia S. Prognostic factors and outcomes in Italian patients undergoing curative gastric cancer surgery. Eur J Surg Oncol. 2014 Mar;40(3):345-51. doi: 10.1016/j.ejso.2013.11.002. Epub 2013 Nov 12. PubMed PMID: 14 24268760. 15: Collins A, Koppen G, Valdiglesias V, Dusinska M, Kruszewski M, Møller P, Rojas E, Dhawan A, Benzie I, Coskun E, Moretti M, Speit G, Bonassi S; ComNet project. The comet assay as a tool for human biomonitoring studies: the ComNet project. Mutat Res Rev Mutat Res. 2014 Jan-Mar;759:27-39. doi: 10.1016/j.mrrev.2013.10.001. Epub 2013 Oct 31. Review. PubMed PMID: 24184488. 16: Ranzi A, Fustinoni S, Erspamer L, Campo L, Gatti MG, Bechtold P, Bonassi S, Trenti T, Goldoni CA, Bertazzi PA, Lauriola P. Biomonitoring of the general population living near a modern solid waste incinerator: a pilot study in Modena, Italy. Environ Int. 2013 Nov;61:88-97. doi: 10.1016/j.envint.2013.09.008. Epub 2013 Oct 5. PubMed PMID: 24103350. 17: Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Dall'Armi V, Zoffoli R, Bonassi S, de Lima JP, Gaspar JF, Pásaro E, Laffon B, Teixeira JP. Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira mine area, Portugal. Environ Int. 2013 Oct;60:163-70. doi: 10.1016/j.envint.2013.08.014. Epub 2013 Sep 13. PubMed PMID: 24036326. 18: Coelho P, Costa S, Costa C, Silva S, Walter A, Ranville J, Pastorinho MR, Harrington C, Taylor A, Dall'Armi V, Zoffoli R, Candeias C, da Silva EF, Bonassi S, Laffon B, Teixeira JP. Biomonitoring of several toxic metal(loid)s in different biological matrices from environmentally and occupationally exposed populations from Panasqueira mine area, Portugal. Environ Geochem Health. 2014 Apr;36(2):255-69. doi: 10.1007/s10653-013-9562-7. Epub 2013 Aug 30. PubMed PMID: 23990171. 19: Volterrani M, Iellamo F, Rosano G, Guarini P, Pusineri E, Bonassi S, Chimini C, Zaccà F, Proto C; SICOA (Società Italiana Cardiologia Ospedalità Accreditata) Investigators. Anticoagulation in "real world" patients with atrial fibrillation in Italy: results from the ISPAF (Indagine Sicoa Paziente Con Fibrillazione Atriale) survey study. Int J Cardiol. 2013 Oct 12;168(5):4729-33. doi: 10.1016/j.ijcard.2013.07.169. Epub 2013 Jul 26. PubMed PMID: 23948115. 20: Tucker JD, Vadapalli M, Joiner MC, Ceppi M, Fenech M, Bonassi S. Estimating the lowest detectable dose of ionizing radiation by the cytokinesis-block micronucleus assay. Radiat Res. 2013 Sep;180(3):284-91. doi: 10.1667/RR3346.1. Epub 2013 Aug 9. PubMed PMID: 23931722. 21: Onder G, Bonassi S, Abbatecola AM, Folino-Gallo P, Lapi F, Marchionni N, Pani L, Pecorelli S, Sancarlo D, Scuteri A, Trifirò G, Vitale C, Zuccaro SM, Bernabei R, Fini M; Geriatrics Working Group of the Italian Medicines Agency. High 15 prevalence of poor quality drug prescribing in older individuals: a nationwide report from the Italian Medicines Agency (AIFA). J Gerontol A Biol Sci Med Sci. 2014 Apr;69(4):430-7. doi: 10.1093/gerona/glt118. Epub 2013 Aug 2. PubMed PMID: 23913935. 22: Bonassi S, Taioli E, Vermeulen R. Omics in population studies: a molecular epidemiology perspective. Environ Mol Mutagen. 2013 Aug;54(7):455-60. doi: 10.1002/em.21805. Epub 2013 Aug 1. PubMed PMID: 23908054. 23: Cadby G, Mukherjee S, Musk AW, Reid A, Garlepp M, Dick I, Robinson C, Hui J, Fiorito G, Guarrera S, Beilby J, Melton PE, Moses EK, Ugolini D, Mirabelli D, Bonassi S, Magnani C, Dianzani I, Matullo G, Robinson B, Creaney J, Palmer LJ. A genome-wide association study for malignant mesothelioma risk. Lung Cancer. 2013 Oct;82(1):1-8. doi: 10.1016/j.lungcan.2013.04.018. Epub 2013 Jul 1. PubMed PMID: 23827383. 24: Volterrani M, Iellamo F, Rosano G, Guarini P, Pusineri E, Bonassi S, Chimini C, Zaccà F, Proto C; SICOA (Società Italiana Cardiologia Ospedalità Accreditata) Investigators. On-target antihypertensive treatment in Italy: the ISPIT (Indagine Sicoa Paziente Iperteso a Target) survey study. Int J Cardiol. 2013 Oct 9;168(4):4403-5. doi: 10.1016/j.ijcard.2013.05.040. Epub 2013 Jun 6. PubMed PMID: 23746462. 25: Matullo G, Guarrera S, Betti M, Fiorito G, Ferrante D, Voglino F, Cadby G, Di Gaetano C, Rosa F, Russo A, Hirvonen A, Casalone E, Tunesi S, Padoan M, Giordano M, Aspesi A, Casadio C, Ardissone F, Ruffini E, Betta PG, Libener R, Guaschino R, Piccolini E, Neri M, Musk AW, de Klerk NH, Hui J, Beilby J, James AL, Creaney J, Robinson BW, Mukherjee S, Palmer LJ, Mirabelli D, Ugolini D, Bonassi S, Magnani C, Dianzani I. Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. PLoS One. 2013 Apr 23;8(4):e61253. doi: 10.1371/journal.pone.0061253. Print 2013. PubMed PMID: 23626673; PubMed Central PMCID: PMC3634031. 26: Fenech M, Kirsch-Volders M, Rossnerova A, Sram R, Romm H, Bolognesi C, Ramakumar A, Soussaline F, Schunck C, Elhajouji A, Anwar W, Bonassi S. HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems. Int J Hyg Environ Health. 2013 Aug;216(5):541-52. doi: 10.1016/j.ijheh.2013.01.008. Epub 2013 Mar 16. Review. PubMed PMID: 23507632. 27: Valdiglesias V, Giunta S, Fenech M, Neri M, Bonassi S. γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies. Mutat Res. 2013 Jul-Sep;753(1):24-40. doi: 10.1016/j.mrrev.2013.02.001. Epub 2013 Feb 13. Review. PubMed PMID: 23416207. 16 28: Pasqua F, Alesii A, Geraneo K, Di Toro S, La Torre G, Sferrazza A, Mastrullo MG, Calzetta L, Bonassi S, Cardaci V, Cesario A. A pilot survey on the quality of life in respiratory rehabilitation carried out in COPD patients with severe respiratory failure: preliminary data of a novel Inpatient Respiratory Rehabilitation Questionnaire (IRRQ). Multidiscip Respir Med. 2012 Nov 20;7(1):46. doi: 10.1186/2049-6958-7-46. PubMed PMID: 23168213; PubMed Central PMCID: PMC3537560. 29: Stigliani S, Coco S, Moretti S, Oberthuer A, Fischer M, Theissen J, Gallo F, Garavent A, Berthold F, Bonassi S, Tonini GP, Scaruffi P. High genomic instability predicts survival in metastatic high-risk neuroblastoma. Neoplasia. 2012 Sep;14(9):823-32. PubMed PMID: 23019414; PubMed Central PMCID: PMC3459278. 30: Di Gaetano C, Voglino F, Guarrera S, Fiorito G, Rosa F, Di Blasio AM, Manzini P, Dianzani I, Betti M, Cusi D, Frau F, Barlassina C, Mirabelli D, Magnani C, Glorioso N, Bonassi S, Piazza A, Matullo G. An overview of the genetic structure within the Italian population from genome-wide data. PLoS One. 2012;7(9):e43759. doi: 10.1371/journal.pone.0043759. Epub 2012 Sep 12. PubMed PMID: 22984441; PubMed Central PMCID: PMC3440425. 31: Ugolini D, Neri M, Bennati L, Canessa PA, Casanova G, Lando C, Leoncini G, Marroni P, Parodi B, Simonassi C, Bonassi S. CREST biorepository for translational studies on malignant mesothelioma, lung cancer and other respiratory tract diseases: Informatics infrastructure and standardized annotation. Exp Ther Med. 2012 Mar;3(3):540-546. Epub 2011 Dec 14. PubMed PMID: 22969926; PubMed Central PMCID: PMC3438688. 32: Ugolini D, Neri M, Cesario A, Marazzi G, Milazzo D, Volterrani M, Bennati L, Bonassi S, Pasqualetti P. Bibliometric analysis of literature in cerebrovascular and cardiovascular diseases rehabilitation: growing numbers, reducing impact factor. Arch Phys Med Rehabil. 2013 Feb;94(2):324-31. doi: 10.1016/j.apmr.2012.08.205. Epub 2012 Aug 23. PubMed PMID: 22922328. 33: Sterzi S, Cesario A, Cusumano G, Corbo G, Lococo F, Biasotti B, Lapenna LM, Magrone G, Dall'armi V, Meacci E, Porziella V, Bonassi S, Margaritora S, Granone P. How best to assess the quality of life in long-term survivors after surgery for NSCLC? Comparison between clinical predictors and questionnaire scores. Clin Lung Cancer. 2013 Jan;14(1):78-87. doi: 10.1016/j.cllc.2012.04.002. Epub 2012 May 17. PubMed PMID: 22607778. 34: Collins A, Anderson D, Coskun E, Dhawan A, Dusinska M, Koppen G, Kruszewski M, Moretti M, Rojas E, Speit G, Valverde M, Bonassi S. Launch of the ComNet (comet network) project on the comet assay in human population studies during the 17 International Comet Assay Workshop meeting in Kusadasi, Turkey (September 13-16, 2011). Mutagenesis. 2012 Jul;27(4):385-6. doi: 10.1093/mutage/ges014. Epub 2012 May 6. PubMed PMID: 22564849. 35: Frustaci A, Neri M, Cesario A, Adams JB, Domenici E, Dalla Bernardina B, Bonassi S. Oxidative stress-related biomarkers in autism: systematic review and meta-analyses. Free Radic Biol Med. 2012 May 15;52(10):2128-41. doi: 10.1016/j.freeradbiomed.2012.03.011. Epub 2012 Apr 18. Review. PubMed PMID: 22542447. 36: Barbanti P, Fofi L, Dall'Armi V, Aurilia C, Egeo G, Vanacore N, Bonassi S. Rizatriptan in migraineurs with unilateral cranial autonomic symptoms: a double-blind trial. J Headache Pain. 2012 Jul;13(5):407-14. doi: 10.1007/s10194-012-0440-y. Epub 2012 Mar 30. PubMed PMID: 22460943; PubMed Central PMCID: PMC3381061. 37: Dusinska M, Staruchova M, Horska A, Smolkova B, Collins A, Bonassi S, Volkovova K. Are glutathione S transferases involved in DNA damage signalling? Interactions with DNA damage and repair revealed from molecular epidemiology studies. Mutat Res. 2012 Aug 1;736(1-2):130-7. doi: 10.1016/j.mrfmmm.2012.03.003. Epub 2012 Mar 20. PubMed PMID: 22450146. 38: Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, Brenner H, Duell EJ, Fabianova E, Field JK, Foretova L, Friis S, Harris CC, Holcatova I, Hong YC, Isla D, Janout V, Kiemeney LA, Kiyohara C, Lan Q, Lazarus P, Lissowska J, Le Marchand L, Mates D, Matsuo K, Mayordomo JI, McLaughlin JR, Morgenstern H, Müeller H, Orlow I, Park BJ, Pinchev M, Raji OY, Rennert HS, Rudnai P, Seow A, Stucker I, Szeszenia-Dabrowska N, Dawn Teare M, Tjønnelan A, Ugolini D, van der Heijden HF, Wichmann E, Wiencke JK, Woll PJ, Yang P, Zaridze D, Zhang ZF, Etzel CJ, Hung RJ. Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. Eur J Cancer. 2012 Sep;48(13):1957-68. doi: 10.1016/j.ejca.2012.01.038. Epub 2012 Mar 19. PubMed PMID: 22436981; PubMed Central PMCID: PMC3445438. 39: Neri M, Ugolini D, Boccia S, Canessa PA, Cesario A, Leoncini G, Mutti L, Bonassi S. Chemoprevention of asbestos-linked cancers: a systematic review. Anticancer Res. 2012 Mar;32(3):1005-13. Review. PubMed PMID: 22399624. 40: Pasqua F, D'Angelillo R, Mattei F, Bonassi S, Biscione GL, Geraneo K, Cardaci V, Ferri L, Ramella S, Granone P, Sterzi S, Crisafulli E, Clini E, Lococo F, Trodella L, Cesario A. Pulmonary rehabilitation following radical chemo-radiation in locally advanced non surgical NSCLC: Preliminary evidences. Lung Cancer. 2012 18 May;76(2):258-9. doi: 10.1016/j.lungcan.2012.01.015. Epub 2012 Mar 2. PubMed PMID: 22386840. 41: Neri M, Bonassi S, Russo P. Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia. Curr Drug Targets. 2012 May;13(5):636-43. Review. PubMed PMID: 22300029. 42: Morandi F, Scaruffi P, Gallo F, Stigliani S, Moretti S, Bonassi S, Gambini C, Mazzocco K, Fardin P, Haupt R, Arcamone G; Italian Cooperative Group for Neuroblastoma, Pistoia V, Tonini GP, Corrias MV. Bone marrow-infiltrating human neuroblastoma cells express high levels of calprotectin and HLA-G proteins. PLoS One. 2012;7(1):e29922. doi: 10.1371/journal.pone.0029922. Epub 2012 Jan 9. PubMed PMID: 22253825; PubMed Central PMCID: PMC3253802. 43: Franceschini M, Ceravolo MG, Agosti M, Cavallini P, Bonassi S, Dall'Armi V, Massucci M, Schifini F, Sale P. Clinical relevance of action observation in upper-limb stroke rehabilitation: a possible role in recovery of functional dexterity. A randomized clinical trial. Neurorehabil Neural Repair. 2012 Jun;26(5):456-62. doi: 10.1177/1545968311427406. Epub 2012 Jan 10. PubMed PMID: 22235059. 44: Coco S, Theissen J, Scaruffi P, Stigliani S, Moretti S, Oberthuer A, Valdora F, Fischer M, Gallo F, Hero B, Bonassi S, Berthold F, Tonini GP. Age-dependent accumulation of genomic aberrations and deregulation of cell cycle and telomerase genes in metastatic neuroblastoma. Int J Cancer. 2012 Oct 1;131(7):1591-600. doi: 10.1002/ijc.27432. Epub 2012 Feb 18. PubMed PMID: 22234802. 45: Rosenberger A, Bickeböller H, McCormack V, Brenner DR, Duell EJ, Tjønneland A, Friis S, Muscat JE, Yang P, Wichmann HE, Heinrich J, Szeszenia-Dabrowska N, Lissowska J, Zaridze D, Rudnai P, Fabianova E, Janout V, Bencko V, Brennan P, Mates D, Schwartz AG, Cote ML, Zhang ZF, Morgenstern H, Oh SS, Field JK, Raji O, McLaughlin JR, Wiencke J, LeMarchand L, Neri M, Bonassi S, Andrew AS, Lan Q, Hu W, Orlow I, Park BJ, Boffetta P, Hung RJ. Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium. Carcinogenesis. 2012 Mar;33(3):587-97. doi: 10.1093/carcin/bgr307. Epub 2011 Dec 22. PubMed PMID: 22198214; PubMed Central PMCID: PMC3291861. 46: Scaruffi P, Morandi F, Gallo F, Stigliani S, Parodi S, Moretti S, Bonassi S, Fardin P, Garaventa A, Zanazzo G, Pistoia V, Tonini GP, Corrias MV. Bone marrow of neuroblastoma patients shows downregulation of CXCL12 expression and presence of IFN signature. Pediatr Blood Cancer. 2012 Jul 15;59(1):44-51. doi: 10.1002/pbc.23339. Epub 2011 Oct 12. PubMed PMID: 21994039. 47: Borioni N, Marinaro P, Celestini S, Del Sole F, Magro R, Zoppi D, Mattei F, 19 Dall' Armi V, Mazzarella F, Cesario A, Bonassi S. Effect of equestrian therapy and onotherapy in physical and psycho-social performances of adults with intellectual disability: a preliminary study of evaluation tools based on the ICF classification. Disabil Rehabil. 2012;34(4):279-87. doi: 10.3109/09638288.2011.605919. Epub 2011 Oct 12. PubMed PMID: 21988646. 48: Ugolini D, Neri M, Cesario A, Bonassi S, Milazzo D, Bennati L, Lapenna LM, Pasqualetti P. Scientific production in cancer rehabilitation grows higher: a bibliometric analysis. Support Care Cancer. 2012 Aug;20(8):1629-38. doi: 10.1007/s00520-011-1253-2. Epub 2011 Sep 1. PubMed PMID: 21881910. 49: Bonassi S, Coskun E, Ceppi M, Lando C, Bolognesi C, Burgaz S, Holland N, Kirsh-Volders M, Knasmueller S, Zeiger E, Carnesoltas D, Cavallo D, da Silva J, de Andrade VM, Demircigil GC, Domínguez Odio A, Donmez-Altuntas H, Gattas G, Giri A, Giri S, Gómez-Meda B, Gómez-Arroyo S, Hadjidekova V, Haveric A, Kamboj M, Kurteshi K, Martino-Roth MG, Montero Montoya R, Nersesyan A, Pastor-Benito S, Favero Salvadori DM, Shaposhnikova A, Stopper H, Thomas P, Torres-Bugarín O, Yadav AS, Zúñiga González G, Fenech M. The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): the role of life-style, host factors, occupational exposures, health status, and assay protocol. Mutat Res. 2011 Nov-Dec;728(3):88-97. doi: 10.1016/j.mrrev.2011.06.005. Epub 2011 Jul 8. Review. PubMed PMID: 21763453. 50: Peters S, Portengen L, Bonassi S, Sram R, Vermeulen R. Intra- and interindividual variability in lymphocyte chromosomal aberrations: implications for cancer risk assessment. Am J Epidemiol. 2011 Aug 15;174(4):490-3. doi: 10.1093/aje/kwr114. Epub 2011 Jun 7. PubMed PMID: 21652601. 51: Albino D, Brizzolara A, Moretti S, Falugi C, Mirisola V, Scaruffi P, Di Candia M, Truini M, Coco S, Bonassi S, Tonini GP. Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration. Int J Dev Biol. 2011;55(1):65-72. doi: 10.1387/ijdb.092970da. PubMed PMID: 21425081. 52: Coco S, Valdora F, Bonassi S, Scaruffi P, Stigliani S, Oberthuer A, Berthold F, Andolfo I, Servidei T, Riccardi R, Basso E, Iolascon A, Tonini GP. Chromosome 9q and 16q loss identified by genome-wide pooled-analysis are associated with tumor aggressiveness in patients with classic medulloblastoma. OMICS. 2011 May;15(5):273-80. doi: 10.1089/omi.2010.0103. Epub 2011 Feb 24. PubMed PMID: 21348762. 53: Cutolo M, Villaggio B, Brizzolara R, Montagna P, Gallo F, Moretti S, Bonassi S, Sulli A, Soldano S. Identification and quantification of selected inflammatory genes modulated by leflunomide and prednisone treatment in early rheumatoid 20 arthritis patients. Clin Exp Rheumatol. 2011 Jan-Feb;29(1):72-9. Epub 2011 Feb 23. PubMed PMID: 21345295. 54: Vitale C, Marazzi G, Pelliccia F, Volterrani M, Cerquetani E, Spoletini I, Mercuro G, Bonassi S, Dall'Armi V, Fini M, Rosano GM. Trimetazidine improves exercise performance in patients with peripheral arterial disease. Pharmacol Res. 2011 Apr;63(4):278-83. doi: 10.1016/j.phrs.2011.01.003. Epub 2011 Jan 8. PubMed PMID: 21220024. 55: Ceppi M, Gallo F, Bonassi S. Study design and statistical analysis of data in human population studies with the micronucleus assay. Mutagenesis. 2011 Jan;26(1):247-52. doi: 10.1093/mutage/geq060. Review. PubMed PMID: 21164209. 56: Fenech M, Holland N, Zeiger E, Chang WP, Burgaz S, Thomas P, Bolognesi C, Knasmueller S, Kirsch-Volders M, Bonassi S. The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells--past, present and future. Mutagenesis. 2011 Jan;26(1):239-45. doi: 10.1093/mutage/geq051. Review. PubMed PMID: 21164208. 57: Bonassi S, El-Zein R, Bolognesi C, Fenech M. Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies. Mutagenesis. 2011 Jan;26(1):93-100. doi: 10.1093/mutage/geq075. Review. PubMed PMID: 21164188. 58: Fenech M, Bonassi S. The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes. Mutagenesis. 2011 Jan;26(1):43-9. doi: 10.1093/mutage/geq050. Review. PubMed PMID: 21164181. 59: Dhillon VS, Thomas P, Iarmarcovai G, Kirsch-Volders M, Bonassi S, Fenech M. Genetic polymorphisms of genes involved in DNA repair and metabolism influence micronucleus frequencies in human peripheral blood lymphocytes. Mutagenesis. 2011 Jan;26(1):33-42. doi: 10.1093/mutage/geq076. Review. PubMed PMID: 21164180. 60: van Leeuwen DM, Pedersen M, Knudsen LE, Bonassi S, Fenech M, Kleinjans JC, Jennen DG. Transcriptomic network analysis of micronuclei-related genes: a case study. Mutagenesis. 2011 Jan;26(1):27-32. doi: 10.1093/mutage/geq074. Review. PubMed PMID: 21164179. 61: Horska A, Mislanova C, Bonassi S, Ceppi M, Volkovova K, Dusinska M. Vitamin C levels in blood are influenced by polymorphisms in glutathione S-transferases. Eur J Nutr. 2011 Sep;50(6):437-46. doi: 10.1007/s00394-010-0147-2. Epub 2010 Dec 9. PubMed PMID: 21152927. 21 62: Cafarotti S, Dall'Armi V, Cusumano G, Margaritora S, Meacci E, Lococo F, Vita ML, Porziella V, Bonassi S, Cesario A, Granone P. Small-bore wire-guided chest drains: safety, tolerability, and effectiveness in pneumothorax, malignant effusions, and pleural empyema. J Thorac Cardiovasc Surg. 2011 Mar;141(3):683-7. doi: 10.1016/j.jtcvs.2010.08.044. Epub 2010 Oct 13. PubMed PMID: 20947099. 63: Moretti S, Fragnelli V, Patrone F, Bonassi S. Using coalitional games on biological networks to measure centrality and power of genes. Bioinformatics. 2010 Nov 1;26(21):2721-30. doi: 10.1093/bioinformatics/btq508. Epub 2010 Sep 3. PubMed PMID: 20817743. 64: Gee GV, Stanifer ML, Christensen BC, Atwood WJ, Ugolini D, Bonassi S, Resnick MB, Nelson HH, Marsit CJ, Kelsey KT. SV40 associated miRNAs are not detectable in mesotheliomas. Br J Cancer. 2010 Sep 7;103(6):885-8. doi: 10.1038/sj.bjc.6605848. Epub 2010 Aug 17. PubMed PMID: 20717113; PubMed Central PMCID: PMC2966630. 65: Ugolini D, Neri M, Casilli C, Bonassi S. Development of search filters for retrieval of literature on the molecular epidemiology of cancer. Mutat Res. 2010 Aug 30;701(2):107-10. doi: 10.1016/j.mrgentox.2010.05.016. Epub 2010 Jun 2. PubMed PMID: 20685344. 66: Albertini G, Bonassi S, Dall'Armi V, Giachetti I, Giaquinto S, Mignano M. Spectral analysis of the voice in Down Syndrome. Res Dev Disabil. 2010 Sep-Oct;31(5):995-1001. doi: 10.1016/j.ridd.2010.04.024. Epub 2010 May 20. PubMed PMID: 20488659. 67: Cutolo M, Villaggio B, Pizzorni C, Paolino S, Moretti S, Gallo F, Bonassi S, Sulli A, Seriolo B, Montagna P, Soldano S. Inflammatory gene profile in early rheumatoid arthritis and modulation by leflunomide and prednisone treatment. Ann N Y Acad Sci. 2010 Apr;1193:15-21. doi: 10.1111/j.1749-6632.2009.05297.x. PubMed PMID: 20398002. 68: Margaritora S, Cesario A, Cusumano G, Cafarotti S, Corbo GM, Ferri L, Ceppi M, Meacci E, Valente S, D'Angelillo RM, Russo P, Porziella V, Bonassi S, Pasqua F, Sterzi S, Granone P. Is pulmonary function damaged by neoadjuvant lung cancer therapy? A comprehensive serial time-trend analysis of pulmonary function after induction radiochemotherapy plus surgery. J Thorac Cardiovasc Surg. 2010 Jun;139(6):1457-63. doi: 10.1016/j.jtcvs.2009.10.023. Epub 2010 Apr 2. PubMed PMID: 20363001. 69: Scaruffi P, Stigliani S, Coco S, Valdora F, De Vecchi C, Bonassi S, Tonini GP. Transcribed-ultra conserved region expression profiling from low-input total RNA. BMC Genomics. 2010 Mar 3;11:149. doi: 10.1186/1471-2164-11-149. PubMed PMID: 20199688; PubMed Central PMCID: PMC2838852. 22 70: Kirsch-Volders M, Bonassi S, Herceg Z, Hirvonen A, Möller L, Phillips DH. Gender-related differences in response to mutagens and carcinogens. Mutagenesis. 2010 May;25(3):213-21. doi: 10.1093/mutage/geq008. Epub 2010 Mar 1. PubMed PMID: 20194421. 71: Ugolini D, Neri M, Casilli C, Ceppi M, Canessa PA, Ivaldi GP, Paganuzzi M, Bonassi S. A bibliometric analysis of scientific production in mesothelioma research. Lung Cancer. 2010 Nov;70(2):129-35. doi: 10.1016/j.lungcan.2010.01.013. Epub 2010 Feb 18. PubMed PMID: 20170978. 72: Margaritora S, Cesario A, Cusumano G, Meacci E, D'Angelillo R, Bonassi S, Carnassale G, Porziella V, Tessitore A, Vita ML, Lauriola L, Evoli A, Granone P. Thirty-five-year follow-up analysis of clinical and pathologic outcomes of thymoma surgery. Ann Thorac Surg. 2010 Jan;89(1):245-52; discussion 252. doi: 10.1016/j.athoracsur.2009.08.074. PubMed PMID: 20103246. 73: Scaruffi P, Stigliani S, Moretti S, Coco S, De Vecchi C, Valdora F, Garaventa A, Bonassi S, Tonini GP. Transcribed-Ultra Conserved Region expression is associated with outcome in high-risk neuroblastoma. BMC Cancer. 2009 Dec 15;9:441. doi: 10.1186/1471-2407-9-441. PubMed PMID: 20003513; PubMed Central PMCID: PMC2804711. 74: Ceppi M, Biasotti B, Fenech M, Bonassi S. Human population studies with the exfoliated buccal micronucleus assay: statistical and epidemiological issues. Mutat Res. 2010 Jul-Sep;705(1):11-9. doi: 10.1016/j.mrrev.2009.11.001. Epub 2009 Nov 20. Review. PubMed PMID: 19932192. 75: Gemignani F, Neri M, Bottari F, Barale R, Canessa PA, Canzian F, Ceppi M, Spitaleri I, Cipollini M, Ivaldi GP, Mencoboni M, Scaruffi P, Tonini GP, Ugolini D, Mutti L, Bonassi S, Landi S. Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism. Mutat Res. 2009 Dec 1;671(1-2):76-83. doi: 10.1016/j.mrfmmm.2009.09.003. Epub 2009 Sep 12. PubMed PMID: 19751749. 76: Cesario A, Dall'Armi V, Cusumano G, Ferri L, Margaritora S, Cardaci V, Cafarotti S, Russo P, Paleari L, Sterzi S, Pasqua F, Bonassi S, Granone P. Post-operative pulmonary rehabilitation after lung resection for NSCLC: a follow up study. Lung Cancer. 2009 Nov;66(2):268-9. doi: 10.1016/j.lungcan.2009.08.002. Epub 2009 Sep 1. PubMed PMID: 19726101. 77: Banelli B, Bonassi S, Casciano I, Mazzocco K, Di Vinci A, Scaruffi P, Brigati C, Allemanni G, Borzì L, Tonini GP, Romani M. Outcome prediction and risk assessment by quantitative pyrosequencing methylation analysis of the SFN gene in 23 advanced stage, high-risk, neuroblastic tumor patients. Int J Cancer. 2010 Feb 1;126(3):656-68. doi: 10.1002/ijc.24768. PubMed PMID: 19626586. 78: Bonassi S, Biasotti B, Kirsch-Volders M, Knasmueller S, Zeiger E, Burgaz S, Bolognesi C, Holland N, Thomas P, Fenech M; HUMNXL Project Consortium. State of the art survey of the buccal micronucleus assay--a first stage in the HUMN(XL) project initiative. Mutagenesis. 2009 Jul;24(4):295-302. doi: 10.1093/mutage/gep019. Epub 2009 May 28. PubMed PMID: 19477934. 79: Thomas P, Holland N, Bolognesi C, Kirsch-Volders M, Bonassi S, Zeiger E, Knasmueller S, Fenech M. Buccal micronucleus cytome assay. Nat Protoc. 2009;4(6):825-37. doi: 10.1038/nprot.2009.53. Epub 2009 May 7. PubMed PMID: 19444240. 80: Rossi AM, Hansteen IL, Skjelbred CF, Ballardin M, Maggini V, Murgia E, Tomei A, Viarengo P, Knudsen LE, Barale R, Norppa H, Bonassi S. Association between frequency of chromosomal aberrations and cancer risk is not influenced by genetic polymorphisms in GSTM1 and GSTT1. Environ Health Perspect. 2009 Feb;117(2):203-8. doi: 10.1289/ehp.11769. Epub 2008 Sep 1. PubMed PMID: 19270789; PubMed Central PMCID: PMC2649221. 81: Filippi U, Brizzolara R, Venuti D, Cesarone A, Maritati VA, Podestà M, Yung WF, Bottaro LC, Orselli A, Chiappori A, Schiavo M, Caputo M, Bonassi S, Bagnasco M. Prevalence of post-partum thyroiditis in Liguria (Italy): an observational study. J Endocrinol Invest. 2008 Dec;31(12):1063-8. PubMed PMID: 19246971. 82: Fenech M, Holland N, Knasmueller S, Burgaz S, Bonassi S. Report on the buccal micronucleus assay workshop organized by the International Human Micronucleus (HUMN) project--Antalya, Turkey 2007. Mutagenesis. 2009 Mar;24(2):199-201. doi: 10.1093/mutage/gen065. Epub 2008 Dec 4. PubMed PMID: 19056855. 83: Ugolini D, Neri M, Canessa PA, Casilli C, Catrambone G, Ivaldi GP, Lando C, Marroni P, Paganuzzi M, Parodi B, Visconti P, Puntoni R, Bonassi S. The CREST biorepository: a tool for molecular epidemiology and translational studies on malignant mesothelioma, lung cancer, and other respiratory tract diseases. Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3013-9. doi: 10.1158/1055-9965.EPI-08-0524. Erratum in: Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1331. multiple author names corrected. PubMed PMID: 18990743. 84: Betti M, Neri M, Ferrante D, Landi S, Biava A, Gemignani F, Bertolotti M, Mirabelli D, Padoan M, Ugolini D, Botta M, Bonassi S, Magnani C, Dianzani I. Pooled analysis of NAT2 genotypes as risk factors for asbestos-related malignant mesothelioma. Int J Hyg Environ Health. 2009 May;212(3):322-9. doi: 10.1016/j.ijheh.2008.08.001. Epub 2008 Oct 1. PubMed PMID: 18838334. 24 85: Moretti S, van Leeuwen D, Gmuender H, Bonassi S, van Delft J, Kleinjans J, Patrone F, Merlo DF. Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution. BMC Bioinformatics. 2008 Sep 2;9:361. doi: 10.1186/1471-2105-9-361. PubMed PMID: 18764936; PubMed Central PMCID: PMC2556684. 86: Albino D, Scaruffi P, Moretti S, Coco S, Truini M, Di Cristofano C, Cavazzana A, Stigliani S, Bonassi S, Tonini GP. Identification of low intratumoral gene expression heterogeneity in neuroblastic tumors by genome-wide expression analysis and game theory. Cancer. 2008 Sep 15;113(6):1412-22. doi: 10.1002/cncr.23720. PubMed PMID: 18671248. 87: Iarmarcovai G, Ceppi M, Botta A, Orsière T, Bonassi S. Micronuclei frequency in peripheral blood lymphocytes of cancer patients: a meta-analysis. Mutat Res. 2008 Sep-Oct;659(3):274-83. doi: 10.1016/j.mrrev.2008.05.006. Epub 2008 Jun 5. Review. PubMed PMID: 18582599. 88: Holland N, Bolognesi C, Kirsch-Volders M, Bonassi S, Zeiger E, Knasmueller S, Fenech M. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat Res. 2008 Jul-Aug;659(1-2):93-108. doi: 10.1016/j.mrrev.2008.03.007. Epub 2008 Apr 11. Review. PubMed PMID: 18514568. 89: Neri M, Ugolini D, Dianzani I, Gemignani F, Landi S, Cesario A, Magnani C, Mutti L, Puntoni R, Bonassi S. Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases. Mutat Res. 2008 Jul-Aug;659(1-2):126-36. doi: 10.1016/j.mrrev.2008.02.002. Epub 2008 Feb 23. Review. PubMed PMID: 18420450. 90: Bonassi S, Norppa H, Ceppi M, Strömberg U, Vermeulen R, Znaor A, Cebulska-Wasilewska A, Fabianova E, Fucic A, Gundy S, Hansteen IL, Knudsen LE, Lazutka J, Rossner P, Sram RJ, Boffetta P. Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22 358 subjects in 11 countries. Carcinogenesis. 2008 Jun;29(6):1178-83. doi: 10.1093/carcin/bgn075. Epub 2008 Mar 19. PubMed PMID: 18356148; PubMed Central PMCID: PMC2443275. 91: Murgia E, Ballardin M, Bonassi S, Rossi AM, Barale R. Validation of micronuclei frequency in peripheral blood lymphocytes as early cancer risk biomarker in a nested case-control study. Mutat Res. 2008 Mar 1;639(1-2):27-34. Epub 2007 Nov 13. PubMed PMID: 18155071. 92: Iarmarcovai G, Bonassi S, Botta A, Baan RA, Orsière T. Genetic polymorphisms 25 and micronucleus formation: a review of the literature. Mutat Res. 2008 Mar-Apr;658(3):215-33. Epub 2007 Oct 22. Review. PubMed PMID: 18037339. 93: Mateuca RA, Roelants M, Iarmarcovai G, Aka PV, Godderis L, Tremp A, Bonassi S, Fenech M, Bergé-Lefranc JL, Kirsch-Volders M. hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo. Mutagenesis. 2008 Jan;23(1):35-41. Epub 2007 Oct 29. PubMed PMID: 17971348. 94: Ugolini D, Neri M, Ceppi M, Cesario A, Dianzani I, Filiberti R, Gemignani F, Landi S, Magnani C, Mutti L, Puntoni R, Bonassi S. Genetic susceptibility to malignant mesothelioma and exposure to asbestos: the influence of the familial factor. Mutat Res. 2008 Mar-Apr;658(3):162-71. Epub 2007 Aug 10. Review. PubMed PMID: 17904414. 95: Fucić A, Znaor A, Strnad M, van der Hel O, Aleksandrov A, Miskov S, Grah J, Sedlar M, Jazbec AM, Ceppi M, Vermeulen R, Boffetta P, Norppa H, Bonassi S. Chromosome damage and cancer risk in the workplace: the example of cytogenetic surveillance in Croatia. Toxicol Lett. 2007 Jul 30;172(1-2):4-11. Epub 2007 May 25. PubMed PMID: 17651925. 96: Bonassi S. [Depleted uranium: the Signum Project]. Epidemiol Prev. 2007 Jan-Feb;31(1):6. Italian. PubMed PMID: 17591395. 97: Ugolini D, Puntoni R, Perera FP, Schulte PA, Bonassi S. A bibliometric analysis of scientific production in cancer molecular epidemiology. Carcinogenesis. 2007 Aug;28(8):1774-9. Epub 2007 Jun 4. PubMed PMID: 17548902. 98: Cesario A, Ferri L, Galetta D, Cardaci V, Biscione G, Pasqua F, Piraino A, Bonassi S, Russo P, Sterzi S, Margaritora S, Granone P. Pre-operative pulmonary rehabilitation and surgery for lung cancer. Lung Cancer. 2007 Jul;57(1):118-9. Epub 2007 May 1. PubMed PMID: 17475363. 99: Cesario A, Ferri L, Galetta D, Pasqua F, Bonassi S, Clini E, Biscione G, Cardaci V, di Toro S, Zarzana A, Margaritora S, Piraino A, Russo P, Sterzi S, Granone P. Post-operative respiratory rehabilitation after lung resection for non-small cell lung cancer. Lung Cancer. 2007 Aug;57(2):175-80. Epub 2007 Apr 17. PubMed PMID: 17442449. 100: Landi S, Gemignani F, Neri M, Barale R, Bonassi S, Bottari F, Canessa PA, Canzian F, Ceppi M, Filiberti R, Ivaldi GP, Mencoboni M, Scaruffi P, Tonini GP, Mutti L, Puntoni R. Polymorphisms of glutathione-S-transferase M1 and manganese superoxide dismutase are associated with the risk of malignant pleural mesothelioma. Int J Cancer. 2007 Jun 15;120(12):2739-43. PubMed PMID: 17290392. 26 101: Fardin P, Moretti S, Biasotti B, Ricciardi A, Bonassi S, Varesio L. Normalization of low-density microarray using external spike-in controls: analysis of macrophage cell lines expression profile. BMC Genomics. 2007 Jan 17;8:17. PubMed PMID: 17229315; PubMed Central PMCID: PMC1797020. 102: Iarmarcovai G, Bonassi S, Sari-Minodier I, Baciuchka-Palmaro M, Botta A, Orsière T. Exposure to genotoxic agents, host factors, and lifestyle influence the number of centromeric signals in micronuclei: a pooled re-analysis. Mutat Res. 2007 Feb 3;615(1-2):18-27. Epub 2007 Jan 2. PubMed PMID: 17198715. 103: Fenech M, Bolognesi C, Kirsch-Volders M, Bonassi S, Zeiger E, Knasmüller S, Holland N. Harmonisation of the micronucleus assay in human buccal cells--a Human Micronucleus (HUMN) project (www.humn.org) initiative commencing in 2007. Mutagenesis. 2007 Jan;22(1):3-4. Epub 2006 Dec 9. PubMed PMID: 17158789. 104: Menardo G, Brizzolara R, Bonassi S, Marchetti A, Dante GL, Pistone C, Marenco D, Rabellino V, Buscaglia S, Scarso R, Murialdo M, Venturino E, Marino CE, Descalzi D, Minetti F, Bagnasco M, Pesce G. Population screening for coeliac disease in a low prevalence area in Italy. Scand J Gastroenterol. 2006 Dec;41(12):1414-20. PubMed PMID: 17101572. 105: Boffetta P, van der Hel O, Norppa H, Fabianova E, Fucic A, Gundy S, Lazutka J, Cebulska-Wasilewska A, Puskailerova D, Znaor A, Kelecsenyi Z, Kurtinaitis J, Rachtan J, Forni A, Vermeulen R, Bonassi S. Chromosomal aberrations and cancer risk: results of a cohort study from Central Europe. Am J Epidemiol. 2007 Jan 1;165(1):36-43. Epub 2006 Oct 27. PubMed PMID: 17071846. 106: Devoto G, Gallo F, Marchello C, Racchi O, Garbarini R, Bonassi S, Albalustri G, Haupt E. Prealbumin serum concentrations as a useful tool in the assessment of malnutrition in hospitalized patients. Clin Chem. 2006 Dec;52(12):2281-5. Epub 2006 Oct 26. PubMed PMID: 17068165. 107: Munnia A, Bonassi S, Verna A, Quaglia R, Pelucco D, Ceppi M, Neri M, Buratti M, Taioli E, Garte S, Peluso M. Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer. Free Radic Biol Med. 2006 Nov 1;41(9):1499-505. Epub 2006 Aug 12. PubMed PMID: 17023277. 108: Trodella L, De Marinis F, D'Angelillo RM, Ramella S, Cesario A, Valente S, Nelli F, Migliorino MR, Margaritora S, Corbo GM, Porziella V, Ciresa M, Cellini F, Bonassi S, Russo P, Cortesi E, Granone P. Induction cisplatin-gemcitabine-paclitaxel plus concurrent radiotherapy and gemcitabine in the multimodality treatment of unresectable stage IIIB non-small cell lung cancer. Lung Cancer. 2006 Dec;54(3):331-8. Epub 2006 Sep 29. PubMed PMID: 27 17011065. 109: Bonassi S, Znaor A, Ceppi M, Lando C, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, Bigatti MP, Bolognesi C, Cebulska-Wasilewska A, Fabianova E, Fucic A, Hagmar L, Joksic G, Martelli A, Migliore L, Mirkova E, Scarfi MR, Zijno A, Norppa H, Fenech M. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis. 2007 Mar;28(3):625-31. Epub 2006 Sep 14. PubMed PMID: 16973674. 110: Norppa H, Bonassi S, Hansteen IL, Hagmar L, Strömberg U, Rössner P, Boffetta P, Lindholm C, Gundy S, Lazutka J, Cebulska-Wasilewska A, Fabiánová E, Srám RJ, Knudsen LE, Barale R, Fucic A. Chromosomal aberrations and SCEs as biomarkers of cancer risk. Mutat Res. 2006 Aug 30;600(1-2):37-45. Epub 2006 Jul 11. Review. PubMed PMID: 16814813. 111: Kirsch-Volders M, Mateuca RA, Roelants M, Tremp A, Zeiger E, Bonassi S, Holland N, Chang WP, Aka PV, Deboeck M, Godderis L, Haufroid V, Ishikawa H, Laffon B, Marcos R, Migliore L, Norppa H, Teixeira JP, Zijno A, Fenech M. The effects of GSTM1 and GSTT1 polymorphisms on micronucleus frequencies in human lymphocytes in vivo. Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):1038-42. PubMed PMID: 16702390. 112: Massimo LM, Wiley TJ, Bonassi S, Caprino D. Longitudinal psychosocial outcomes in two cohorts of adult survivors from childhood acute leukemia treated with or without cranial radiation. Minerva Pediatr. 2006 Feb;58(1):1-7. PubMed PMID: 16541001. 113: Ugolini D, Neri M, Knudsen LE, Bonassi S, Merlo DF. Searching PubMed for molecular epidemiology studies: the case of chromosome aberrations. Environ Mol Mutagen. 2006 May;47(4):227-9. PubMed PMID: 16416429. 114: Coco S, Defferrari R, Scaruffi P, Cavazzana A, Di Cristofano C, Longo L, Mazzocco K, Perri P, Gambini C, Moretti S, Bonassi S, Tonini GP. Genome analysis and gene expression profiling of neuroblastoma and ganglioneuroblastoma reveal differences between neuroblastic and Schwannian stromal cells. J Pathol. 2005 Nov;207(3):346-57. PubMed PMID: 16178058. 115: Neri M, Ceppi M, Knudsen LE, Merlo DF, Barale R, Puntoni R, Bonassi S. Baseline micronuclei frequency in children: estimates from meta- and pooled analyses. Environ Health Perspect. 2005 Sep;113(9):1226-9. PubMed PMID: 16140632; PubMed Central PMCID: PMC1280406. 116: Banelli B, Gelvi I, Di Vinci A, Scaruffi P, Casciano I, Allemanni G, Bonassi S, Tonini GP, Romani M. Distinct CpG methylation profiles characterize different 28 clinical groups of neuroblastic tumors. Oncogene. 2005 Aug 25;24(36):5619-28. PubMed PMID: 16044164. 117: Neri M, Ugolini D, Bonassi S, Fucic A, Holland N, Knudsen LE, Srám RJ, Ceppi M, Bocchini V, Merlo DF. Children's exposure to environmental pollutants and biomarkers of genetic damage. II. Results of a comprehensive literature search and meta-analysis. Mutat Res. 2006 Jan;612(1):14-39. Epub 2005 Jul 18. PubMed PMID: 16027031. 118: Neri M, Bonassi S, Knudsen LE, Sram RJ, Holland N, Ugolini D, Merlo DF. Children's exposure to environmental pollutants and biomarkers of genetic damage. I. Overview and critical issues. Mutat Res. 2006 Jan;612(1):1-13. Epub 2005 Jul 5. Review. PubMed PMID: 16002329. 119: Neri M, Filiberti R, Taioli E, Garte S, Paracchini V, Bolognesi C, Canessa PA, Fontana V, Ivaldi GP, Verna A, Bonassi S, Puntoni R. Pleural malignant mesothelioma, genetic susceptibility and asbestos exposure. Mutat Res. 2005 Dec 30;592(1-2):36-44. Epub 2005 Jul 1. PubMed PMID: 15993904. 120: Banelli B, Di Vinci A, Gelvi I, Casciano I, Allemanni G, Bonassi S, Romani M. DNA methylation in neuroblastic tumors. Cancer Lett. 2005 Oct 18;228(1-2):37-41. Review. PubMed PMID: 15923079. 121: Rossner P, Boffetta P, Ceppi M, Bonassi S, Smerhovsky Z, Landa K, Juzova D, Srám RJ. Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer. Environ Health Perspect. 2005 May;113(5):517-20. PubMed PMID: 15866756; PubMed Central PMCID: PMC1257540. 122: Fenech M, Baghurst P, Luderer W, Turner J, Record S, Ceppi M, Bonassi S. Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, beta-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability--results from a dietary intake and micronucleus index survey in South Australia. Carcinogenesis. 2005 May;26(5):991-9. Epub 2005 Feb 10. PubMed PMID: 15705599. 123: Bonassi S, Ugolini D, Kirsch-Volders M, Strömberg U, Vermeulen R, Tucker JD. Human population studies with cytogenetic biomarkers: review of the literature and future prospectives. Environ Mol Mutagen. 2005 Mar-Apr;45(2-3):258-70. Review. PubMed PMID: 15688363. 124: Scaruffi P, Parodi S, Mazzocco K, Defferrari R, Fontana V, Bonassi S, Tonini GP. Detection of MYCN amplification and chromosome 1p36 loss in neuroblastoma by cDNA microarray comparative genomic hybridization. Mol Diagn. 2004;8(2):93-100. PubMed PMID: 15527323. 29 125: Peluso M, Neri M, Margarino G, Mereu C, Munnia A, Ceppi M, Buratti M, Felletti R, Stea F, Quaglia R, Puntoni R, Taioli E, Garte S, Bonassi S. Comparison of DNA adduct levels in nasal mucosa, lymphocytes and bronchial mucosa of cigarette smokers and interaction with metabolic gene polymorphisms. Carcinogenesis. 2004 Dec;25(12):2459-65. Epub 2004 Aug 19. PubMed PMID: 15319297. 126: Bonassi S, Znaor A, Norppa H, Hagmar L. Chromosomal aberrations and risk of cancer in humans: an epidemiologic perspective. Cytogenet Genome Res. 2004;104(1-4):376-82. Review. PubMed PMID: 15162068. 127: Toraason M, Albertini R, Bayard S, Bigbee W, Blair A, Boffetta P, Bonassi S, Chanock S, Christiani D, Eastmond D, Hanash S, Henry C, Kadlubar F, Mirer F, Nebert D, Rapport S, Rest K, Rothman N, Ruder A, Savage R, Schulte P, Siemiatycki J, Shields P, Smith M, Tolbert P, Vermeulen R, Vineis P, Wacholder S, Ward E, Waters M, Weston A. Applying new biotechnologies to the study of occupational cancer--a workshop summary. Environ Health Perspect. 2004 Mar;112(4):413-6. PubMed PMID: 15033588; PubMed Central PMCID: PMC1241892. 128: Hagmar L, Strömberg U, Bonassi S, Hansteen IL, Knudsen LE, Lindholm C, Norppa H. Impact of types of lymphocyte chromosomal aberrations on human cancer risk: results from Nordic and Italian cohorts. Cancer Res. 2004 Mar 15;64(6):2258-63. PubMed PMID: 15026371. 129: Bonassi S, Lando C, Ceppi M, Landi S, Rossi AM, Barale R. No association between increased levels of high-frequency sister chromatid exchange cells (HFCs) and the risk of cancer in healthy individuals. Environ Mol Mutagen. 2004;43(2):134-6. PubMed PMID: 14991754. 130: Puntoni R, Filiberti R, Cerrano PG, Neri M, Andreatta R, Bonassi S. Implementation of a molecular epidemiology approach to human pleural malignant mesothelioma. Mutat Res. 2003 Nov;544(2-3):385-96. Review. PubMed PMID: 14644341. 131: Neri M, Fucic A, Knudsen LE, Lando C, Merlo F, Bonassi S. Micronuclei frequency in children exposed to environmental mutagens: a review. Mutat Res. 2003 Nov;544(2-3):243-54. Review. PubMed PMID: 14644326. 132: Hadjidekova VB, Bulanova M, Bonassi S, Neri M. Micronucleus frequency is increased in peripheral blood lymphocytes of nuclear power plant workers. Radiat Res. 2003 Dec;160(6):684-90. PubMed PMID: 14640795. 133: Parodi S, Muselli M, Fontana V, Bonassi S. ROC curves are a suitable and flexible tool for the analysis of gene expression profiles. Cytogenet Genome Res. 2003;101(1):90-1. PubMed PMID: 14571143. 30 134: Cotellessa M, Barbieri P, Mazzella M, Bonassi S, Minicucci L, Lorini R. High incidence of childhood type 1 diabetes in Liguria, Italy, from 1989 to 1998. Diabetes Care. 2003 Jun;26(6):1786-9. PubMed PMID: 12766110. 135: Taioli E, Bonassi S. Pooled analysis of epidemiological studies involving biological markers. Int J Hyg Environ Health. 2003 Mar;206(2):109-15. PubMed PMID: 12708232. 136: Bonassi S, Neri M, Lando C, Ceppi M, Lin YP, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Fenech M; HUMN collaborative group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat Res. 2003 Mar;543(2):155-66. PubMed PMID: 12644185. 137: Tinnerberg H, Heikkilä P, Huici-Montagud A, Bernal F, Forni A, Wanders S, Welinder H, Wilhardt P, Strömberg U, Norppa H, Knudsen L, Bonassi S, Hagmar L. Retrospective exposure assessment and quality control in an international multi-centre case-control study. Ann Occup Hyg. 2003 Jan;47(1):37-47. PubMed PMID: 12505905. 138: Fenech M, Chang WP, Kirsch-Volders M, Holland N, Bonassi S, Zeiger E; HUman MicronNucleus project. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res. 2003 Jan 10;534(1-2):65-75. PubMed PMID: 12504755. 139: Fenech M, Bonassi S, Turner J, Lando C, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Bigatti MP, Bolognesi C, Cao J, De Luca G, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hadjidekova VV, Hrelia P, Jaworska A, Joksic G, Krishnaja AP, Lee TK, Martelli A, McKay MJ, Migliore L, Mirkova E, Müller WU, Odagiri Y, Orsiere T, Scarfì MR, Silva MJ, Sofuni T, Surralles J, Trenta G, Vorobtsova I, Vral A, Zijno A; HUman MicroNucleus project. Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project. Mutat Res. 2003 Jan 10;534(1-2):45-64. 140: Taioli E, Bonassi S. Methodological issues in pooled analysis of biomarker studies. Mutat Res. 2002 Sep;512(1):85-92. Review. PubMed PMID: 12220591. 141: Bonassi S, Au WW. Biomarkers in molecular epidemiology studies for health risk prediction. Mutat Res. 2002 Mar;511(1):73-86. Review. PubMed PMID: 11906843. 142: Durante M, Bonassi S, George K, Cucinotta FA. Risk estimation based on 31 chromosomal aberrations induced by radiation. Radiat Res. 2001 Nov;156(5 Pt 2):662-7. PubMed PMID: 11604089. 143: Bonassi S, Neri M, Puntoni R. Validation of biomarkers as early predictors of disease. Mutat Res. 2001 Sep 1;480-481:349-58. Review. PubMed PMID: 11506827. 144: Bonassi S, Fenech M, Lando C, Lin YP, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, Bigatti MP, Bolognesi C, Jia C, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hrelia P, Krishnaja AP, Lee TK, Migliore L, Mikhalevich L, Mirkova E, Mosesso P, Müller WU, Odagiri Y, Scarffi MR, Szabova E, Vorobtsova I, Vral A, Zijno A. HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ Mol Mutagen. 2001;37(1):31-45. PubMed PMID: 11170240. 145: Bonassi S, Hagmar L, Strömberg U, Montagud AH, Tinnerberg H, Forni A, Heikkilä P, Wanders S, Wilhardt P, Hansteen IL, Knudsen LE, Norppa H. Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. European Study Group on Cytogenetic Biomarkers and Health. Cancer Res. 2000 Mar 15;60(6):1619-25. PubMed PMID: 10749131. 146: Fenech M, Holland N, Chang WP, Zeiger E, Bonassi S. The HUman MicroNucleus Project--An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res. 1999 Jul 16;428(1-2):271-83. Review. PubMed PMID: 10517999. 147: Bonassi S. Combining environmental exposure and genetic effect measurements in health outcome assessment. Mutat Res. 1999 Jul 16;428(1-2):177-85. PubMed PMID: 10517991. 148: Bolognesi C, Lando C, Forni A, Landini E, Scarpato R, Migliore L, Bonassi S. Chromosomal damage and ageing: effect on micronuclei frequency in peripheral blood lymphocytes. Age Ageing. 1999 Jul;28(4):393-7. PubMed PMID: 10459794. 149: Hagmar L, Bonassi S, Strömberg U, Mikoczy Z, Lando C, Hansteen IL, Montagud AH, Knudsen L, Norppa H, Reuterwall C, Tinnerberg H, Brøgger A, Forni A, Högstedt B, Lambert B, Mitelman F, Nordenson I, Salomaa S, Skerfving S. Cancer predictive value of cytogenetic markers used in occupational health surveillance programs. Recent Results Cancer Res. 1998;154:177-84. Review. PubMed PMID: 10026999. 150: Bonassi S, Fontana V, Ceppi M, Barale R, Biggeri A. Analysis of correlated data in human biomonitoring studies. The case of high sister chromatid exchange frequency cells. Mutat Res. 1999 Jan 2;438(1):13-21. PubMed PMID: 9858669. 32 151: Hagmar L, Bonassi S, Strömberg U, Brøgger A, Knudsen LE, Norppa H, Reuterwall C. Chromosomal aberrations in lymphocytes predict human cancer: a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res. 1998 Sep 15;58(18):4117-21. PubMed PMID: 9751622. 152: Hagmar L, Bonassi S, Strömberg U, Mikoczy Z, Lando C, Hansteen IL, Montagud AH, Knudsen L, Norppa H, Reuterwall C, Tinnerberg H, Brogger A, Forni A, Högstedt B, Lambert B, Mitelman F, Nordenson I, Salomaa S, Skerfving S. Cancer predictive value of cytogenetic markers used in occupational health surveillance programs: a report from an ongoing study by the European Study Group on Cytogenetic Biomarkers and Health. Mutat Res. 1998 Sep 20;405(2):171-8. PubMed PMID: 9748557. 153: Miele M, Bonassi S, Bonatti S, Martini E, Miglio L, Ottaggio L, Queirolo P, Sertoli M, Abbondandolo A. Micronucleus analysis in peripheral blood lymphocytes from melanoma patients treated with dacarbazine. Anticancer Res. 1998 May-Jun;18(3B):1967-71. PubMed PMID: 9677451. 154: Lando C, Hagmar L, Bonassi S. [Biomarkers of cytogenetic damage in humans and risk of cancer. The European Study Group on Cytogenetic Biomarkers and Health (ESCH)]. Med Lav. 1998 Mar-Apr;89(2):124-31. Italian. PubMed PMID: 9673102. 155: Redaelli A, Magrassi R, Bonassi S, Abbondandolo A, Frosina G. AP endonuclease activity in humans: development of a simple assay and analysis of ten normal individuals. Teratog Carcinog Mutagen. 1998;18(1):17-26. PubMed PMID: 9586767. 156: Pagano G, Bonassi S, De Biase A, Degan P, Deeva IB, Doronin YK, Iaccarino M, Oral R, Warnau M, Korkina LG. L-methionine induces stage-dependent changes of differentiation and oxidative activity in sea urchin embryogenesis. Pharmacol Toxicol. 1997 Sep;81(3):134-43. PubMed PMID: 9335071. 157: Montanaro F, Ceppi M, Demers PA, Puntoni R, Bonassi S. Mortality in a cohort of tannery workers. Occup Environ Med. 1997 Aug;54(8):588-91. PubMed PMID: 9326162; PubMed Central PMCID: PMC1128983. 158: Bolognesi C, Abbondandolo A, Barale R, Casalone R, Dalprà L, De Ferrari M, Degrassi F, Forni A, Lamberti L, Lando C, Migliore L, Padovani P, Pasquini R, Puntoni R, Sbrana I, Stella M, Bonassi S. Age-related increase of baseline frequencies of sister chromatid exchanges, chromosome aberrations, and micronuclei in human lymphocytes. Cancer Epidemiol Biomarkers Prev. 1997 Apr;6(4):249-56. Review. PubMed PMID: 9107430. 159: Bonassi S, Forni A, Bigatti P, Canevarollo N, De Ferrari M, Lando C, 33 Padovani P, Bevegni M, Stella M, Vecchio D, Puntoni R. Chromosome aberrations in hospital workers: evidence from surveillance studies in Italy (1963-1993). Am J Ind Med. 1997 Mar;31(3):353-60. PubMed PMID: 9055959. 160: Peluso M, Amasio E, Bonassi S, Munnia A, Altrupa F, Parodi S. Detection of DNA adducts in human nasal mucosa tissue by 32P-postlabeling analysis. Carcinogenesis. 1997 Feb;18(2):339-44. PubMed PMID: 9054626. 161: Campomenosi P, Ottaggio L, Moro F, Urbini S, Bogliolo M, Zunino A, Camoriano A, Inga A, Gentile SL, Pellegata NS, Bonassi S, Bruzzone E, Iannone R, Pisani R, Menichini P, Ranzani GN, Bonatti S, Abbondandolo A, Fronza G. Study on aneuploidy and p53 mutations in astrocytomas. Cancer Genet Cytogenet. 1996 Jun;88(2):95-102. PubMed PMID: 8640734. 162: Bonassi S, Montanaro F, Ceppi M, Abbondandolo A. Is human exposure to styrene a cause of cytogenetic damage? A re-analysis of the available evidence. Biomarkers. 1996;1(4):217-25. doi: 10.3109/13547509609079361. PubMed PMID: 23888988. 163: Bonassi S, Bolognesi C, Abbondandolo A, Barale R, Bigatti P, Camurri L, Dalpra L, De Ferrari M, Forni A, Lando C, et al. Influence of sex on cytogenetic end points: evidence from a large human sample and review of the literature. Cancer Epidemiol Biomarkers Prev. 1995 Sep;4(6):671-9. Review. PubMed PMID: 8547835. 164: Artuso M, Angotzi G, Bonassi S, Bonatti S, De Ferrari M, Gargano D, Lastrucci L, Miligi L, Sbrana C, Abbondandolo A. Cytogenetic biomonitoring of styrene-exposed plastic boat builders. Arch Environ Contam Toxicol. 1995 Aug;29(2):270-4. PubMed PMID: 7661632. 165: Puntoni R, Toninelli F, Zhankui L, Bonassi S. Mathematical modelling in risk/exposure assessment of tobacco related lung cancer. Carcinogenesis. 1995 Jul;16(7):1465-71. PubMed PMID: 7614679. 166: Degan P, Bonassi S, De Caterina M, Korkina LG, Pinto L, Scopacasa F, Zatterale A, Calzone R, Pagano G. In vivo accumulation of 8-hydroxy-2'-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families. Carcinogenesis. 1995 Apr;16(4):735-41. PubMed PMID: 7728950. 167: Bonassi S, Abbondandolo A, Camurri L, Dal Prá L, De Ferrari M, Degrassi F, Forni A, Lamberti L, Lando C, Padovani P, et al. Are chromosome aberrations in circulating lymphocytes predictive of future cancer onset in humans? Preliminary results of an Italian cohort study. Cancer Genet Cytogenet. 1995 Feb;79(2):133-5. 34 PubMed PMID: 7889505. 168: Filiberti R, Kubík A, Reissigová J, Merlo F, Bonassi S. Cancer, cardiovascular mortality, and diet in Italy and the Czech Republic. Neoplasma. 1995;42(5):275-83. PubMed PMID: 8552209. 169: Mazzella M, Cotellessa M, Bonassi S, Mulas R, Caratozzolo A, Gaber S, Romano C. Incidence of type I diabetes in the Liguria Region, Italy. Results of a prospective study in a 0- to 14-year age-group. Diabetes Care. 1994 Oct;17(10):1193-6. PubMed PMID: 7821142. 170: Bonassi S, Magnani M, Calvi A, Repetto E, Puglisi P, Pantarotto F, Lazzaroni F. Factors related to drug consumption during pregnancy. Acta Obstet Gynecol Scand. 1994 Aug;73(7):535-40. PubMed PMID: 8079603. 171: Bonassi S, Ceppi M, Fontana V, Merlo F. Multiple regression analysis of cytogenetic human data. Mutat Res. 1994 Aug;313(1):69-80. PubMed PMID: 7519312. 172: Lazzaroni F, Bonassi S, Magnani M, Calvi A, Repetto E, Serra F, Podestà F, Pearce N. Moderate maternal drinking and outcome of pregnancy. Eur J Epidemiol. 1993 Nov;9(6):599-606. PubMed PMID: 8150062. 173: Toma S, Venturino A, Sogno G, Formica C, Bignotti B, Bonassi S, Palumbo R. Metastatic bone tumors. Nonsurgical treatment. Outcome and survival. Clin Orthop Relat Res. 1993 Oct;(295):246-51. PubMed PMID: 8403656. 174: Bolognesi C, Parrini M, Merlo F, Bonassi S. Frequency of micronuclei in lymphocytes from a group of floriculturists exposed to pesticides. J Toxicol Environ Health. 1993 Oct-Nov;40(2-3):405-11. PubMed PMID: 8230311. 175: Kubík A, Bonassi S, Filiberti R, Reissigová J. Regional and national variation in lung cancer mortality in Italy and Czechoslovakia. Eur J Cancer Prev. 1993 Jul;2(4):337-44. PubMed PMID: 8358286. 176: Bolognesi C, Parrini M, Bonassi S, Ianello G, Salanitto A. Cytogenetic analysis of a human population occupationally exposed to pesticides. Mutat Res. 1993 Feb;285(2):239-49. PubMed PMID: 7678897. 177: Bolognesi C, Parrini M, Reggiardo G, Merlo F, Bonassi S. Biomonitoring of workers exposed to pesticides. Int Arch Occup Environ Health. 1993;65(1 Suppl):S185-7. PubMed PMID: 8406923. 178: Lazzaroni F, Bonassi S, Magnani M, Puglisi P, Salomone P, Pantarotto F, Mazzeo P, Cotelessa G, Norelli MT, Santi F, et al. [Alcohol in pregnancy and 35 fetal health]. Minerva Pediatr. 1993 Jan-Feb;45(1-2):47-53. Review. Italian. PubMed PMID: 8316163. 179: Lazzaroni F, Bonassi S, Magnani M, Puglisi P, Salomone P, Pantarotto F, Mazzeo P, Cotelessa G, Norelli MT, Santi F, et al. [Effects of moderate maternal drinking on some neonatal parameters]. Minerva Pediatr. 1992 Oct;44(10):511-7. Italian. PubMed PMID: 1287437. 180: Lattere M, Rosati U, Chiossi M, Facco F, Magnani M, Calvi A, Renna S, Bonassi S. [The pediatric emergency department: assessment of clinical activity and interaction with local health authorities]. Minerva Pediatr. 1992 Sep;44(9):407-12. Italian. PubMed PMID: 1474968. 181: Facco F, Grazi G, Bonassi S, Magnani M, Di Pietro P. Chlamydial and rickettsial transmission through tick bite in children. Lancet. 1992 Apr 18;339(8799):992-3. PubMed PMID: 1348825. 182: Toma S, Leonessa F, Romanini A, Badellino F, Bonassi S, Nicolo G, Rosso R. Predictive value of some clinical and pathological parameters on upper level axillary lymph node involvement in breast cancer. Anticancer Res. 1991 Jul-Aug;11(4):1439-43. PubMed PMID: 1746901. 183: De Ferrari M, Artuso M, Bonassi S, Bonatti S, Cavalieri Z, Pescatore D, Marchini E, Pisano V, Abbondandolo A. Cytogenetic biomonitoring of an Italian population exposed to pesticides: chromosome aberration and sister-chromatid exchange analysis in peripheral blood lymphocytes. Mutat Res. 1991 May;260(1):105-13. PubMed PMID: 2027334. 184: Lazzaroni F, Bonassi S, Manniello E, Morcaldi L, Repetto E, Ruocco A, Calvi A, Cotellessa G. Effect of passive smoking during pregnancy on selected perinatal parameters. Int J Epidemiol. 1990 Dec;19(4):960-6. PubMed PMID: 2084028. 185: Bonassi S, Merlo F, Puntoni R, Ferraris F, Bottura G. [Epidemics of lung tumors in a Biella tannery]. Epidemiol Prev. 1990 Sep;12(44):25-30. Italian. PubMed PMID: 2151133. 186: Cafiero F, Gipponi M, Bonalumi U, Vecchio C, Bonassi S, Bertoglio S, Mereu P, Percivale P. [Pre-operative identification of patients at risk for septic complications after surgery for neoplasms of the digestive system. A multiphasic multicenter study]. Minerva Chir. 1989 Oct 31;44(20):2169-80. Italian. PubMed PMID: 2695858. 187: Bonassi S, Merlo F, Pearce N, Puntoni R. Bladder cancer and occupational exposure to polycyclic aromatic hydrocarbons. Int J Cancer. 1989 Oct 36 15;44(4):648-51. PubMed PMID: 2793238. 188: Puntoni R, Goldsmith DF, Valerio F, Vercelli M, Bonassi S, Di Giorgio F, Ceppi M, Stagnaro E, Filiberti R, Santi L, et al. A cohort study of workers employed in a refractory brick plant. Tumori. 1988 Feb 29;74(1):27-33. PubMed PMID: 2832986. 189: Puntoni R, Bolognesi C, Bonassi S, Merlo F, Mari A, Merialdo G, Santi L. Cancer risk evaluation in an area with a high density of chemical plants. An interdisciplinary approach. Ann N Y Acad Sci. 1988;534:808-16. Review. PubMed PMID: 3291728. 190: De Ambrosis A, Ferrari N, Bonassi S, Vidali G. Nucleosomal repeat length in active and inactive genes. FEBS Lett. 1987 Dec 10;225(1-2):120-2. PubMed PMID: 3691798. 191: Toma S, Coialbu T, Bonassi S, Nicolò G, Rosso R. A multifactorial analysis of different biological and clinical parameters in breast cancer. Anticancer Res. 1987 May-Jun;7(3 Pt B):401-7. PubMed PMID: 3631893. 192: Toma S, Bonassi S, Puntoni R, Nicolò G. Primary tumor site, size, patients age and axillary lymph nodes in breast cancers. Tumori. 1986 Jun 30;72(3):259-65. PubMed PMID: 3739006. 193: Gipponi M, Sciutto C, Accornero L, Bonassi S, Raso C, Vignolo C, Cafiero F. Assessing modifications of the intestinal bacterial flora in patients on long-term oral treatment with bacampicillin or amoxicillin: a random study. Chemioterapia. 1985 Jun;4(3):214-7. PubMed PMID: 4028281. 194: Bonassi S, Ceppi M, Puntoni R, Valerio F, Vercelli M, Belli S, Biocca M, Comba P, Ticchiarelli L, Mariotti F, et al. Mortality studies of dockyard workers (longshoremen) in Italy. Am J Ind Med. 1985;7(3):219-27. PubMed PMID: 3985014. 195: Puntoni R, Valerio A, Cresta E, Filiberti R, Bonassi S, Vercelli M. [Mortality among workers in a tannery]. Med Lav. 1984 Nov-Dec;75(6):471-7. Italian. PubMed PMID: 6533447. Roma, 20 maggio 2015 37