Sergio Scaccianoce - Facoltà di Farmacia e Medicina

DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA
CURRICULUM DIDATTICO-SCIENTIFICO DEL PROF. SERGIO SCACCIANOCE
DATI PERSONALI
Nome e Cognome
SERGIO SCACCIANOCE
Luogo e data di nascita:
Roma 19 Marzo 1958
Stato Civile:
Coniugato
Dipartimento
Indirizzo
Fisiologia e Farmacologia
Piazza Aldo Moro, 5 - Roma
Telefono uff./lab./mobile
06 4991 2511
Fax
06 4991 2511
E-mail
[email protected]
Settore Scientifico-Disciplinare: BIO/14 – FARMACOLOGIA
Orario di Ricevimento: Mercoledì 12-16; Giovedì 12-16.
ATTUALE POSIZIONE
Professore Aggregato
CARRIERA E TITOLI
Dottore in Scienze Biologiche
Visiting Scientist a:
Londra (St. Thoma’s Hospital)
Budapest (Postgraduate Medical School)
Cambridge (Radcliffe Hospital)
(anno 2010 - ) Presidente C.d.L Infermieristica "T" in Professioni Sanitarie
Infermieristiche
ATTIVITA’ DIDATTICA
1.
2.
3.
4.
5.
6.
Farmacologia (I), del C.L.M. "A" in Farmacia e Medicina
Farmacologia (II), del C.L.M. "A" in Farmacia e Medicina
Patologia integrata V, del C.L.M. "A" in Farmacia e Medicina
Medicina Clinica e Farmacologia, del C.d.L Infermieristica "T" in Professioni
Sanitarie Infermieristiche
Elementi di Primo Soccorso e di Scienze Chirurgiche, del C.d.L Igiene Dentale "B" in
Professioni Sanitarie Tecniche Assistenziali
Scuole di Specializzazione in Farmacologia
Curriculum Vitae
Pagina 1
Scuole di Specializzazione in Neurologia
8. Scuole di Specializzazione in Medicina Nucleare
7.
ATTIVITA’ SCIENTIFICA
Direzione di gruppi di ricerca nell’ambito di progetti finanziati da CNR, Ministero della
salute, Ministero dell’Università, Università Sapienza e privati. Collaborazioni
intradipartimentali, aziende farmaceutiche, Department of Anaesthesiology, LudwigMaximilians University, Munich, Germany, Department of Psychiatry, College of Medicine,
University of Illinois Chicago, Chicago, Illinois, USA.
Le principali tematiche delle ricerche svolte presso il Dipartimento di Fisiologia e
Farmacologia riguardano temi di neuropsicofarmacologia, farmacologia neonatale e
tossicologia delle sostanze d’abuso.
PUBBLICAZIONI SCIENTIFICHE
A. Peer reviewed publications of Sergio SCACCIANOCE: selezionate (ultimi 15 anni)
1
Nativio P, Pascale E, Maffei A, Scaccianoce S, Passarelli F.
Effect of stress on hippocampal nociceptin expression in rat.
Stress. 2011 in stampa
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Hauer D, Ratano P, Morena M, Scaccianoce S, Briegel I, Palmery M, Cuomo V,
Roozendaal B, Schelling G, Campolongo P.
Propofol enhances memory formation via an interaction with the endocannabinoid
system.
Anesthesiology. 2011 Jun;114(6):1380-8.
Matrisciano F, Busceti CL, Bucci D, Orlando R, Caruso A, Molinaro G, Cappuccio I,
Riozzi B, Gradini R, Motolese M, Caraci F, Copani A, Scaccianoce S, Melchiorri D,
Bruno V, Battaglia G, Nicoletti F.
Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced
hippocampal damage.
PLoS One. 2011 Jan 27;6(1):e16447.
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Gaetani S, Fu J, Cassano T, Dipasquale P, Romano A, Righetti L, Cianci S, Laconca
L, Giannini E, Scaccianoce S, Mairesse J, Cuomo V, Piomelli D.
The fat-induced satiety factor oleoylethanolamide suppresses feeding through
central release of oxytocin.
J Neurosci. 2010 Jun 16;30(24):8096-101.
Milella MS, Passarelli F, De Carolis L, Schepisi C, Nativio P, Scaccianoce S, Nencini
P.
Opposite roles of dopamine and orexin in quinpirole-induced excessive drinking: a
rat model of psychotic polydipsia.
Psychopharmacology (Berl). 2010 Aug;211(3):355-66.
Matrisciano F, Nasca C, Molinaro G, Riozzi B, Scaccianoce S, Raggi MA, Mercolini
L, Biagioni F, Mathè AA, Sanna E, Maciocco E, Pignatelli M, Biggio G, Nicoletti F.
Enhanced expression of the neuronal K+/Cl- cotransporter, KCC2, in spontaneously
depressed Flinders Sensitive Line rats.
Curriculum Vitae
2.553
5.486
4.411
7.271
3.817
Pagina 2
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Brain Res. 2010 Apr 14;1325:112-20.
Matrisciano F, Modafferi AM, Togna GI, Barone Y, Pinna G, Nicoletti F, Scaccianoce
S.
Repeated anabolic androgenic steroid treatment causes antidepressant-reversible
alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior.
Neuropharmacology. 2010 Jun;58(7):1078-84.
Liberatore M, Pala A, Scaccianoce S, Anagnostou C, Di Tondo U, Calandri E, D'Elia
P, Gross MD, Rubello D.
Microbial targeting of 99mTc-labeled recombinant human beta-defensin-3 in an
animal model of infection: a feasibility pilot study.
J Nucl Med. 2009 May;50(5):823-6.
Grandi D, Solenghi E, Guerrini R, Broccardo M, Agostini S, Petrella C,
Scaccianoce S, Improta G, Morini G.
The hypothalamus-pituitary-adrenal axis does not influence the protective
effects of nociceptin/orphanin FQ on the rat gastric mucosa.
Regul Pept. 2009 Apr 10;154(1-3):32-8.
Carratù MR, Coluccia A, Modafferi AM, Borracci P, Scaccianoce S, Sakamoto
M, Cuomo V.
Prenatal methylmercury exposure: effects on stress response during active
learning.
Bull Environ Contam Toxicol. 2008 Dec;81(6):539-42.
Modafferi AM, Diana M, Nicoletti F, Scaccianoce S.
Morphine withdrawal increases metabotropic glutamate 2/3 receptors
expression in nucleus accumbens.
Neuroreport. 2008 Jun 11;19(9):911-4.
Matrisciano F, Bonaccorso S, Ricciardi A, Scaccianoce S, Panaccione I, Wang
L, Ruberto A, Tatarelli R, Nicoletti F, Girardi P, Shelton RC.
Changes in BDNF serum levels in patients with major depression disorder
(MDD) after 6 months treatment with sertraline, escitalopram, or
venlafaxine.
J Psychiatr Res. 2009 Jan;43(3):247-54
Barbaccia ML, Scaccianoce S, Del Bianco P, Campolongo P, Trezza V, Tattoli
M, Cuomo V, Steardo L.
Cognitive impairment and increased brain neurosteroids in adult rats
perinatally exposed to low millimolar blood alcohol concentrations.
Psychoneuroendocrinology. 2007 Sep-Nov;32(8-10):931-42.
Scaccianoce S, Del Bianco P, Paolone G, Caprioli D, Modafferi AM, Nencini
P, Badiani A.
Social isolation selectively reduces hippocampal brain-derived neurotrophic
factor without altering plasma corticosterone.
Behav Brain Res. 2006 Apr 3;168(2):323-5.
Broccardo M, Scaccianoce S, Del Bianco P, Agostini S, Petrella C, Improta G
Curriculum Vitae
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1.139
1.822
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Pagina 3
Nociceptin/orphanin FQ-induced delay in gastric emptying: role of central
corticotropin-releasing factor and glucocorticoid receptors.
Neurogastroenterol Motil. 2005 Dec;17(6):871-7.
16 Matrisciano F, Scaccianoce S, Del Bianco P, Panaccione I, Canudas AM,
Battaglia G, Riozzi B, Ngomba RT, Molinaro G, Tatarelli R, Melchiorri D,
Nicoletti F.
Metabotropic glutamate receptors and neuroadaptation to antidepressants:
imipramine-induced down-regulation of beta-adrenergic receptors in mice
treated with metabotropic glutamate 2/3 receptor ligands.
J Neurochem. 2005 Jun;93(5):1345-52.
17 Scaccianoce S, Mattei V, Del Bianco P, Gizzi C, Sorice M, Hiraiwa M, Misasi
R.
Hippocampal prosaposin changes during stress: a glucocorticoidindependent event.
Hippocampus. 2004;14(3):275-80
18 Scaccianoce S, Del Bianco P, Pannitteri G, Passarelli F.
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4.609
Relationship between stress and circulating levels of S100B protein.
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Brain Res. 2004 Apr 9;1004(1-2):208-11
Scaccianoce S, Del Bianco P, Caricasole A, Nicoletti F, Catalani A.
Relationship between learning, stress and hippocampal brain-derived
neurotrophic factor.
Neuroscience. 2003;121(4):825-8.
Scaccianoce S, Matrisciano F, Del Bianco P, Caricasole A, Di Giorgi Gerevini
V, Cappuccio I, Melchiorri D, Battaglia G, Nicoletti F.
Endogenous activation of group-II metabotropic glutamate receptors
inhibits the hypothalamic-pituitary-adrenocortical axis.
Neuropharmacology. 2003 Apr;44(5):555-61.
Matrisciano F, Storto M, Ngomba RT, Cappuccio I, Caricasole A, Scaccianoce
S, Riozzi B, Melchiorri D, Nicoletti F.
Imipramine treatment up-regulates the expression and function of mGlu2/3
metabotropic glutamate receptors in the rat hippocampus.
Neuropharmacology. 2002 Jun;42(8):1008-15.
Catalani A, Casolini P, Cigliana G, Scaccianoce S, Consoli C, Cinque C, Zuena
AR, Angelucci L.
Maternal corticosterone influences behavior, stress response and
corticosteroid receptors in the female rat.
Pharmacol Biochem Behav. 2002 Aug;73(1):105-14.
Scaccianoce S, Catalani A, Lombardo K, Consoli C, Angelucci L.
Maternal glucocorticoid hormone influences nerve growth factor expression
in the developing rat brain.
Neuroreport. 2001 Sep 17;12(13):2881-4
Curriculum Vitae
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3.215
4.677
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Pagina 4
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Scaccianoce S, Lombardo K, Nicolai R, Affricano D, Angelucci L.
Studies on the involvement of histamine in the hypothalamic-pituitaryadrenal axis activation induced by nerve growth factor.
Life Sci. 2000 Nov 17;67(26):3143-52.
Catalani A, Casolini P, Scaccianoce S, Patacchioli FR, Spinozzi P, Angelucci
L
Maternal corticosterone during lactation permanently affects brain
corticosteroid receptors, stress response and behaviour in rat progeny.
Neuroscience. 2000;100(2):319-25
Scaccianoce S, Lombardo K, Angelucci L.
Nerve growth factor brain concentration and stress: changes depend on type
of stressor and age.
Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):469-79.
Scaccianoce S, Alemà GS, Cigliana G, Nicolai R, Buttarelli FR, Angelucci L.
Neurotoxicity of Kainate to the Hippocampus is not Accrued by Aging,
Stress and Exogenous Corticosterone in Wistar Kyoto and Spontaneously
Hypertensive Rats.
Stress. 1997 Aug;1(4):201-212.
Calogero AE, Scaccianoce S, Burrello N, Nicolai R, Muscolo LA, Kling MA,
Angelucci L, D'Agata R.
The kappa-opioid receptor agonist MR-2034 stimulates the rat
hypothalamic-pituitary-adrenal axis: studies in vivo and in vitro.
J Neuroendocrinol. 1996 Aug;8(8):579-85
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LIBRI
Compendio di farmacologia generale e speciale (Ed: Del Tacca, Caputi, Amico Roxas)
UTET.
Curriculum Vitae
Pagina 5