LUIGI PIRTOLI

Pirtoli, Luigi
CURRICULUM VITAE and PUBLICATIONS
Full Professor of Radiological Sciences (MED36)
Biographical data
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Insitution and Location
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+39 0577233390 (Mob: 3290386455)
[email protected]
Italian (mother language),
English (spoken, written),
French (written)
- Via G. Pietri 11, 53100
Siena
- Nuovo Policlinico, Via
delle Scotte, 53100 Siena
Italy
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Main fields of interest and skills
(scientific, professional)
Professional Experiences (dates)
Other Professional & Scientific
Experiences
Management experiences
Italy (Giuggianello, LE)
September 1, 1948
Married
Italy
Post-Graduate, Radiology,
University of Florence,
Italy, July 1977
Graduate, Medicine,
University of Florence,
Italy, November 1973
Radiotherapy, Oncology, Radiobiology, Oncologic Imaging
- University
Professore Ordinario (Full Professor), Diagnostica per
Immagini e Radioterapia (MED 36) Università di Siena (24 X
2000 to present);
Chair, Post-Graduate School in Radiotherapy, Università di
Siena (1986 to present);
Professore Associato (Associate Professor), Diagnostica per
Immagini e Radioterapia (MED 36) Università di Siena
(12/V/86);
Aiuto (Vice-Director), Diagnostica per Immagini e
Radioterapia (MED 36) Università di Siena (14/IV/83);
Assistente di Ruolo (Assistant Professor), Diagnostica per
Immagini e Radioterapia (F18X) Università di Siena
(11/X/82);
Assistente di Ruolo (Assistant Professor),, Radiologia (F18X)
Università di Firenze, (16/V/78);
Assistente Incaricato (Resident), Radiologia (F18X) Università di
Firenze (18/XI/77)
- National Italian Health Service (Tuscany Region)
Present Position: Director, Unità Operativa di Radioterapia, Azienda
Ospedaliera Universitaria, Siena
- Muqdisho (Jamhuuriyadda Fedraalka Soomaaliya), General
Hospital, Assistant Radiologist: June to August, 1975
- Temple University, Philadelphia, USA, Dept. of Biotechnology,
Adjunct Professor: October, 2012 to present
- Former Director, Imaging Department of the Azienda
Ospedaliera Universitaria, Siena;
Chairman and Committee
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The most relevant 20 publications
of the last 10 years (PubMed:
2003 to 2012)
Former Director, Department of Human Pathology and
Oncology, University of Siena;
Present Position: Director of the Medical Section, Department
of Oncology, Azienda Ospedaliera Universitaria, Siena;
Direction Office (Member), the Tuscany Tumor Institute;
Board of Governors (Member), the Tuscany Tumor Institute’s
Foundation;
Past-President (2010-2012, the Italian Association of
Radiobiology (AIRB)
AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in
autophagy-induced astrocytoma cells. Fassina L, Magenes G, Inzaghi A, Palumbo S, Allavena
G, Miracco C, Pirtoli L, Biggiogera M, Comincini S. Eur J Histochem. 2012 Oct 11;56(4):e44.
doi: 10.4081/ejh.2012.e44. PMID: 23361240
Assessment of response to chemoradiation therapy in rectal cancer using MR volumetry based
on diffusion-weighted data sets: a preliminary report. Carbone SF, Pirtoli L, Ricci V, Venezia D,
Carfagno T, Lazzi S, Mourmouras V, Lorenzi B, Volterrani L. Radiol Med. 2012 Oct;117(7):111224. doi: 10.1007/s11547-012-0829-3. Epub 2012 May 14. PMID: 22580810
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by
the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology).
Scoccianti S, Magrini SM, Ricardi U, Detti B, Krengli M, Parisi S, Bertoni F, Sotti G, Cipressi S,
Tombolini V, Dall'oglio S, Lioce M, Saieva C, Buglione M, Mantovani C, Rubino G, Muto P,
Fusco V, Fariselli L, de Renzis C, Masini L, Santoni R, Pirtoli L, Biti G. Neuro Oncol. 2012
Jun;14(6):798-807. doi: 10.1093/neuonc/nos081. Epub 2012 Apr 25. PMID: 22539339
Diffusion-weighted MR volumetry for assessing the response of rectal cancer to combined
radiation therapy with chemotherapy. Carbone SF, Pirtoli L, Ricci V, Carfagno T, Tini P, Lazzi
S, Volterrani L. Radiology. 2012 Apr;263(1):311. doi: 10.1148/radiol.12112454. PMID:22438457
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation
and temozolomide combined treatments. Palumbo S, Pirtoli L, Tini P, Cevenini G, Calderaro F,
Toscano M, Miracco C, Comincini S. J Cell Biochem. 2012 Jul;113(7):2308-18. doi:
10.1002/jcb.24102. PMID: 22345070
Silencing of cellular prion protein (PrPC) expression by DNA-antisense oligonucleotides induces
autophagy-dependent cell death in glioma cells. Barbieri G, Palumbo S, Gabrusiewicz K, Azzalin
A, Marchesi N, Spedito A, Biggiogera M, Sbalchiero E, Mazzini G, Miracco C, Pirtoli L,
Kaminska B, Comincini S.
Autophagy. 2011 Aug;7(8):840-53. Epub 2011 Aug 1. PMID: 21478678
β-catenin and Gli1 are prognostic markers in glioblastoma. Rossi M, Magnoni L, Miracco C, Mori
E, Tosi P, Pirtoli L, Tini P, Oliveri G, Cosci E, Bakker A. Cancer Biol Ther. 2011 Apr
15;11(8):753-61. Epub 2011 Apr 15. PMID: 21321483
Spindle cell lipoma of the orbit: a case report of an unusual orbital pathology. Ulivieri S, Olivieri
G, Motolese PA, Fruschelli M, Motolese E, Menicacci F, Galluzzi P, Bellini M, Giorgio A, Toti P,
Pirtoli L. Neurol Neurochir Pol. 2010 Jul-Aug;44(4):419-23. PMID: 20827617
Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma
multiforme treated between 2002 and 2007: a multicenter study by the Central Nervous System
Study Group of Airo (italian Association of Radiation Oncology). Scoccianti S, Magrini SM,
Ricardi U, Detti B, Buglione M, Sotti G, Krengli M, Maluta S, Parisi S, Bertoni F, Mantovani C,
Tombolini V, De Renzis C, Lioce M, Fatigante L, Fusco V, Muto P, Berti F, Rubino G, Cipressi S,
Fariselli L, Lupattelli M, Santoni R, Pirtoli L, Biti G. Neurosurgery. 2010 Aug;67(2):446-58. doi:
10.1227/01.NEU.0000371990.86656.E8. PMID: 20644432
Lymphoepithelioma-like carcinoma of the endometrium. Ambrosio MR, Rocca BJ, Mourmouras
V, Onorati M, Mastrogiulio MG, Di Mari N, Pirtoli L, Santopietro R. Pathologica. 2010
Apr;102(2):57-61. PMID: 23596758
Three-dimensional conformal radiotherapy, temozolomide chemotherapy, and high-dose
fractionated stereotactic boost in a protocol-driven, postoperative treatment schedule for highgrade gliomas. Pirtoli L, Rubino G, Marsili S, Oliveri G, Vannini M, Tini P, Miracco C, Santoni R.
Tumori. 2009 May-Jun;95(3):329-37. PMID: 19688972
The prognostic role of Beclin 1 protein expression in high-grade gliomas. Pirtoli L, Cevenini G,
Tini P, Vannini M, Oliveri G, Marsili S, Mourmouras V, Rubino G, Miracco C. Autophagy. 2009
Oct;5(7):930-6. Epub 2009 Oct 8. PMID: 19556884
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Miracco C,
Cosci E, Oliveri G, Luzi P, Pacenti L, Monciatti I, Mannucci S, De Nisi MC, Toscano M,
Malagnino V, Falzarano SM, Pirtoli L, Tosi P. Int J Oncol. 2007 Feb;30(2):429-36. PMID:
17203225
Patterns of practice and survival in a retrospective analysis of 1722 adult astrocytoma patients
treated between 1985 and 2001 in 12 Italian radiation oncology centers. Magrini SM, Ricardi U,
Santoni R, Krengli M, Lupattelli M, Cafaro I, Scoccianti S, Menichelli C, Bertoni F, Enrici RM,
Tombolini V, Buglione M, Pirtoli L. Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):788-99. Epub
2006 May 6. PMID: 16682131
Usefulness of CDX2 in the diagnosis of extramammary Paget disease associated with
malignancies of intestinal type. De Nisi MC, D'Amuri A, Toscano M, Lalinga AV, Pirtoli L,
Miracco C. Br J Dermatol. 2005 Sep;153(3):677-9. PMID: 16120171
High concentrations of activin A in the peritoneal fluid of women with epithelial ovarian cancer.
Cobellis L, Reis FM, Luisi S, Danero S, Pirtoli L, Scambia G, Petraglia F. J Soc Gynecol
Investig. 2004 May;11(4):203-6. PMID: 15120692
[Radiotherapy of malignant gliomas: results from conventional treatment methods and the
prospects of advanced techniques]. Rubino G, Sacco P, Cerase A, Volterrani L, Sebaste L, Pepi
F, Pirtoli L. Radiol Med. 2004 Jan-Feb;107(1-2):128-35. English, Italian. PMID: 15031704
In situ detection of telomeres by fluorescence in situ hybridization and telomerase activity in
glioblastoma multiforme: correlation with p53 status, EGFR, c-myc, MIB1, and Topoisomerase
IIalpha protein expression. Miracco C, De Santi MM, Luzi P, Lalinga AV, Laurini L, De Nisi MC,
Angeloni G, Brogi M, Cardone C, Carducci A, Arcuri F, Tosi P, Rubino G, Pirtoli L. Int J Oncol.
2003 Dec;23(6):1529-35. PMID: 14612923
Evaluation of MDR1, LRP, MRP, and topoisomerase IIalpha gene mRNA transcripts before and
after interferon-alpha, and correlation with the mRNA expression level of the telomerase
subunits hTERT and TEP1 in five unselected human melanoma cell lines. Miracco C, Maellaro
E, Pacenti L, Del Bello B, Valentini MA, Rubegni P, Pirtoli L, Volpi C, Santopietro R, Tosi P. Int
J Oncol. 2003 Jul;23(1):213-20.
Carcinoma with eccrine differentiation arising in a seborrhoeic keratosis. Miracco C, Angeloni G,
Miracco F, Pirtoli L. Br J Dermatol. 2003 Apr;148(4):831-3. PMID: 12752157