DESENZANO.progr_Layout 1

3 Italian experience
rd
in biomedical research:
young minds at work
Desenzano del Garda (BS) • Park Hotel
23-24 ottobre 2015
Faculty
2
GIULIA ABATE
ARIANNA BATTISTI
MICHELA BERTUZZI
IBRAHIM BITAR
SILVIA BOLZANI
LEONARDO BONTEMPI
GIULIA CACCIOTTI
FRANCESCA CACCURI
LUNA COLAGROSSI
MARIASOFIA CALTAGIRONE
FEDERICA CAMPILONGO
FRANCESCA CAPPELLETTI
ILARIA CARLI
ARNALDO CARUSO
NAGAIA CIACCI
CHIARA CIPRIANI
MASSIMO CLEMENTI
ELENA CRISCUOLO
ANTONIO CURTONI
GIOVANNA DESOLE
DOMENICO DI CARLO
FRANCESCA FALASCA
LORENA FALLARINO
ROBERTO FERRARESE
GIANLUIGI FRANCI
DIEGO GALLI
PAOLO GRUMATI
MICHELA GUARIENTI
LUCIA HENRICI DE ANGELIS
MARIA LUISA IARIA
GABRIELE IBBA
LAURA INFURNARI
MICHELE LAI
MARIAGRAZIA MARZIANO
PIETRO MAZZUCA
LORENZO MESSA
DAVIDE MILETO
BARBARA MONTICO
FEDERICA MORELLI
GIORGIO PALÙ
AURORA PIAZZA
GIORGIO PICCINELLI
STEFANO PICCOLO
MARIKA PREMOLI
MARGHERITA ROMEO
ALDA SALDAN
FRANCESCO SANTORO
ELENA TIBALDI
ELENA TOSONI
ANDREA ZENDRINI
Dear Colleagues,
We are pleased to announce the 3rd Annual Italian Experience in
Biomedical Research: Young Minds at Work, which will take place
in Desenzano del Garda (BS) on the 23rd and 24th of October, 2015.
This conference is open to young scientists from across all biomedical disciplines involved in innovative research (PhD students, postgraduates, Post-Doctoral Scientists, etc.). This meeting presents a
unique opportunity for young scientists and researchers to gain exposure and visibility, while exchanging knowledge and fostering
meaningful interactions that may facilitate future projects and collaborations. Furthermore, this experience may potentially inspire the
development of new programs such as the integration of PhD and
Specialization programs, the establishment of nationwide standards, and additional European funding.
In keeping with the tradition established in the first and second Edition of this meeting, students play a fundamental role in both the
organization of the conference and its scientific content. Once
again, the meeting will be conducted exclusively in English for both
oral and written communication. Each interested participant must
submit an English Abstract (300 words maximum) with the following format: Title, Affiliation, Background, Methods, Results, Conclusion.
A committee will review submitted abstracts and select those to be
presented. Each presentation will be limited to 15 minutes, with 5
minutes for questions. Each presentation will be evaluated and the
top three presentations will be selected for recognition.
Registration is free, however, the conference will host a maximum
of 100 participants. The registration will include access to the presentations as well as coffee breaks, and lunch for the 24th of October. All additional costs (Hotel bookings etc.) will be at the expense
of the participants. There are affordable hotels available near the
Congress Center, and we will soon provide a list with respective prices. The deadline for both conference registration and abstract submissions is October 2nd, 2015; and must be submitted via mail to:
[email protected].
We look forward to receiving submissions from across all biomedical
research divisions from young research scientists in your programs
and departments. Please feel free to share this invitation with
anyone who might be interested in attending.
Your participation in this conference is important to us, and we hope
to meet you in Desenzano del Garda!
Kind regards,
Prof. Arnaldo Caruso
Prof. Massimo Clementi
Prof. Giorgio Palù
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Friday, October 23
PARTECIPANTS REGISTRATION
h 13.00-14.00
OPENING AND WELCOME
h 14.00-14.15
Giorgio Palù, Massimo Clementi, Arnaldo Caruso
STEM CELLS
Chairman: Giorgio Palù
h 14.15-15.00 KN - Stefano Piccolo, University of Padua
YAP/TAZ in organ growth, somatic stem cells and cancer
h 15.00-15.15 Giovanna Desole, University of Padua
Comparison of induced pluripotent stem cells (iPSCs) reprogramming
methods based on retroviral vectors, Sendai virus vectors and episomal
vectors
ANTICANCER THERAPY
Chairmen: Michele Lai and Diego Galli
h 15.15-15.30 Elena Tibaldi, University of Padua
Novel fingolimod analogues: a new tool for switching off Lyn-dependent oncogenic signals in Chronic Lymphcytic Leukemia
h 15.30-15.45 Francesca Caccuri, University of Brescia
HHV-6 U94 inhibits motility, migration and invasiveness of human breast cancer cells by modulation of Src signalling pathway
h 15.45-16.00 Michele Lai, S. Anna Institute of Pisa
Ablation of Acid Ceramidase induces apoptosis, growth arrest and senescence in melanoma cells
h 16.00-16.15 Diego Galli, University of Brescia
Genetic polymorphisms as a stratification factor that contributes to
identify patients at high risk of developing Anthracycline-induced cardiomyopathy
BREAK
h 16.15-16.30
AUTOPHAGY AND APOPTOSIS
Chairmen: Paolo Grumati and Barbara Montico
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h 16.30-16.45 Barbara Montico, IRCCS-National Cancer Institute
of Aviano (PN)
Phospholipid scramblase 1 at the cross-road between autophagy and
apoptosis in mantle cell lymphoma
h 16.45-17.00 Pietro Mazzuca, University of Brescia
Role of HIV-1 matrix protein p17 and its variant in autophagy in lymphatic endothelial cells (LECs)
h 17.00-17.15 Paolo Grumati, Goethe University School of Medicine,
Germany
Regulation of endoplasmic reticulum turnover by FAM134B mediated
selective autophagy
PROTEIN MISFOLDING AND PATHOLOGY
Chairmen: Margherita Romeo and Francesca Caccuri
h 17.15-17.30 Margherita Romeo, Mario Negri Institute of Milan
Cardiac light chain amyloidosis: the key role for metal ions revealed by
the C. elegans model. New therapeutic perspectives
h 17.30-17.45 Federica Morelli, Mario Negri Institute of Milan
HIV-1 matrix protein p17 and AIDS related dementia: correlation between protein misfolding and in vivo toxicity using the C. elegans model
h 17.45-18.00 Federica Campilongo, University of Brescia
Role of HIV-1 matrix protein p17 variants in Lymphoma Pathogenesis
CELL-MICROBE INTERACTION
Chairmen: Gianluigi Franci and Chiara Cipriani
h 18.00-18.15 Gianluigi Franci, II University of Naples
Plasmodium falciparum: Invasion of erythocytes through mechanisms
of protein export
h 18.15-18.30 Elena Tosoni, University of Padua
Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription
h 18.30-18.45 Chiara Cipriani, Tor Vergata University, Rome
Transcriptional activity of different endogenous retrovirus (ERV) families and pro-inflammatory cytokines in a mouse model of Autis
h 18.45-19.00 Maria Luisa Iaria, University of Brescia
Phosphatidylinositol-(4,5)-bisphosphate driven
unconventional secretion of biologically active
HIV-1 matrix protein p17
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Saturday, October 24
GENERAL BACTERIOLOGY
Chairmen: Mariasofia Caltagirone and Lucia Henrici De Angelis
h 08.30-08.45 Ibrahim Bitar, University of Pavia
Acinetobacter baumannii ST78 Italian Clinical Strains: a hypothesis of
MDR to XDR evolution
h 08.45-09.00 Mariasofia Caltagirone, University of Pavia
Clinical Isolation of an Enterobacter cloacae Strain Producing the Novel
Plasmid-Borne AmpC ACT-24 Variant
h 09.00-09.15 Antonio Curtoni, University of Turin
MALDI-TOF MS application in direct identification of microorganisms
from positive blood culture
h 09.15-09.30 Aurora Piazza, University of Pavia
A Travel-Related Case of NDM-5-Producing Escherichia coli in Northen
Italy
h 09.30-09.45 Giorgio Piccinelli, University of Brescia
A cluster of invasive listeriosis in Brescia, Italy
h 09.45-10.00 Lucia Henrici De Angelis, University of Siena
Genotypic and virulence characterisation of the first hypermucoviscous
Klebsiella quasipneumoniae subsp. quasipneumoniae isolate from a
bloodstream infection
h 10.00-10.15 Laura Infurnari, University Vita-Salute San Raffaele, Milan
The fecal microbiome as risk stratification marker of enteric sepsis and
acute graft-versus-host disease (GVHD) in hemopoietic stem-cell allotransplanted patients
h 10.15-10.30 Roberto Ferrarese, University Vita-Salute San Raffaele,
Milan
Apolipoprotein E (ApoE) Modulates Systemic Inflammatory Profile and
Gut Microbiota in Response to “Western Diet” in Mice
6
BREAK
h 10.30-10.45
DRUG DEVELOPMENT AND BIOMARKERS
Chairmen: Michela Bertuzzi and Ilaria Carli
h 10.45-11.00 Michela Bertuzzi, University of Brescia
A proteomic approach to compare Erythropoietin and its biosimilars
h 11.00-11.15 Michela Guarienti, University of Brescia
Computational and functional analysis of biopharmaceutical drugs in
zebrafish: erythropoietin as a test model
h 11.15-11.30 Lorenzo Messa, University of Padua
The homodimerization of Human Papillomavirus oncoprotein E6: a potential new druggable antiviral targe
h 11.30-11.45 Ilaria Carli, University of Padua
Sennoside A from Rheum palmatum (L) affects HIV-1 replication at
early post-entry steps of the virus life cycle
h 11.45-12.00 Andrea Zendrini, University of Brescia
Plasmonic Exosomes
NEURODEGENERATION
Chairmen: Marika Premoli and Giulia Abate
h 12.00-12.15 Marika Premoli, University of Brescia
NF-κB p50 knock-out mice as animal model of neurodevelopmental disorders
h 12.15-12.30 Leonardo Bontempi, University of Brescia
Role of nicotinic and dopamine D3 receptor crosstalk in the regulation
of dopaminergic neurons plasticity
h 12.30-12.45 Mariagrazia Marziano, University of Brescia
Correlation between antioxidant enzymes, oxidative stress markers
and conformational altered p53 protein in Alzheimer’s Disease
h 12.45-13.00 Giulia Abate, University of Brescia
Comparison of extracellular and intracellular blood compartments highlights redox alterations in Alzheimer’s and Mild Cognitive Impairment patients
LUNCH
h 13.00-14.30
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Saturday, October 24
GENERAL VIROLOGY
Chairmen: Francesco Santoro and Gabriele Ibba
h 14.30-14.45 Francesco Santoro, University of Siena
Induction and characterization of prophage Ф1207.3 in Streptococcus
pneumoniae
h 14.45-15.00 Nagaia Ciacci, University of Florence
Molecular and physiological characterization of a new lytic bacteriophage against KPC-positive Klebsiella pneumoniae
h 15.00-15.15 Gabriele Ibba, University of Sassari
Codon usage optimization affects the tissue-specificity of the JC polyomavirus
CONTROL OF INFECTION AND MICROBIAL RESISTANCE
Chairmen: Silvia Bolzani and Luna Colagrossi
h 15.15-15.30 Alda Saldan, University of Padua
Human cytomegalovirus infection in pregnancy: immune correlates to
CMV vertical transmission
h 15.30-15.45 Silvia Bolzani, University of Ferrara
KIR2DL2 expressing NK cells: effect on HSV-1 infection control
h 15.45-16.00 Arianna Battisti, Tor Vergata University, Rome
A high HBsAg genetic complexity can influence HBV immunogenicity
in the setting of acute infection
h 16.00-16.15 Luna Colagrossi, Tor Vergata University, Rome
A hyper-glycosylation of HBV surface antigen correlates with immunosuppression-driven HBV reactivation and strongly affects HBsAg quantification in vitro
BREAK
h 16.15-16.30
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ANTIVIRAL THERAPY AND DRUG RESISTANCE
Chairmen: Elena Criscuolo and Domenico Di Carlo
h 16.30-16.45 Francesca Cappelletti, University Vita-Salute San
Raffaele, Milan
Human monoclonal antibody endowed with anti-HSV-1 and -2 activity
strongly inhibits virus replication
h 16.45-17.00 Elena Criscuolo, University Vita-Salute San Raffaele, Milan
In vivo protection conferred by human monoclonal antibody directed
against HSV-1 and 2
h 17.00-17.15 Lorena Fallarino, University of Padua
Anti HIV-1 gene therapy strategies combining multiple siRNA with the
membrane-anchored fusion inhibitor C-peptide “maC46”
h 17.15-17.30 Domenico Di Carlo, Tor Vergata University, Rome
Virological response and tropism evolution in pluri-experienced HIV-1
infected patients starting maraviroc in clinical practice
h 17.30-17.45 Francesca Falasca, Sapienza University, Rome
Full viral suppression, residual viremia and low level viremia in HIV-1
ART treated patients: risk of virological rebound/failure and association
with inflammation markers and HIV-1 DNA
h 17.45-18.00 Davide Mileto, Luigi Sacco Hospital, Milan
Clinical usefulness of drug resistance test at low viremia levels
h 18.00-18.15 Giulia Cacciotti, Sapienza University, Rome
Variation in interferon sensitivity and induction among Usutu and West
Nile (lineage 1 and 2)
DESENZANO AWARDS
h 18.15-18.30
TAKE HOME MESSAGE
h 18.30-18.45
Massimo Clementi, Arnaldo Caruso, Giorgio Palù
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Informazioni Generali
SEDE
PARK HOTEL****
Lungolago C. Battisti 17 - 25015 Desenzano del Garda (Brescia) - Italia
COME RAGGIUNGERE DESENZANO
AUTOSTRADA MILANO-VENEZIA
Uscita Desenzano - 2 Km dal centro
FERROVIA MILANO-VENEZIA
Stazione Ferroviaria di Desenzano - 1 Km dal centro
AEROPORTI
“G. D’Annunzio” (Brescia) - 15 Km da Desenzano
“V. Catullo” (Verona) - 24 Km da Desenzano
Linate-Malpensa (Milano) - 110 Km da Desenzano
Orio al Serio (Bergamo) - 70 Km da Desenzano
IN AUTOBUS
Utilizzando le numerose linee disponibili
IN BATTELLO
Utilizzando i traghetti presenti su tutto
il lago di Garda a cura della
"NAVIGAZIONE LAGO DI GARDA"
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Informazioni Generali
ISCRIZIONI
La quota di iscrizione è gratuita e include: Partecipazione ai lavori congressuali
• Abstract book • Kit Congressuale • Attestato di frequenza • Coffee Break e Colazione lavoro di sabato 24 ottobre.
Saranno accettate le prime 100 Iscrizioni sulla base della temporalità. Per informazioni e iscrizioni rivolgersi a:
Sig.ra Rossi Elisabetta
Laboratorio di Virologia ed Indagini Microbiologiche
Piazzale Spedali Civili, 1 - 25123 Brescia - Tel. +39 030 3995652
Fax +39 030 395258 - E-mail: [email protected]
PRENOTAZIONE ALBERGHIERA
Sono stati opzionati alberghi di diverse tipologie, di seguito in elenco. Ogni partecipante deve prenotare e saldare direttamente la propria prenotazione contattando direttamente l’hotel.
PARKhotel (4 stelle)
Lungolago C. Battisti 17, Desenzano del Garda - Lago di Garda - Brescia
E-mail: [email protected]
Tel +39 030 9143494 - Fax +39 030 9142280
Costi: Doppia Uso Singola € 90,00 - Doppia vista centro storico € 130,00
I prezzi si intendono per camera a notte con prima colazione
Non comprendono tassa di soggiorno € 1,00 per persona per notte.
HOTEL PIROSCAFO (3 stelle)
Via Porto Vecchio 11, Desenzano del Garda - Lago di Garda - Brescia
Tel +39 030 9141128 - E-mail: [email protected]
Costi: SGL € 55,00 - Doppia Uso Singola € 65,00
Doppia € 85,00 - Tripla € 110,00
I prezzi si intendono per camera a notte con prima colazione
Non comprendono tassa di soggiorno € 0,80 per persona per notte.
HOTEL CITY (3 stelle)
Via Nazario Sauro 29, Desenzano del Garda - Lago di Garda - Brescia
E-mail: [email protected] - Tel +39 030 9911704
Costi Comfort: Doppia Uso Singola € 58,00 - Doppia € 88,00
Costi Superior: Doppia Uso Singola € 68,00 - Doppia € 98,00
I prezzi si intendono per camera a notte con prima colazione
Non comprendono tassa di soggiorno € 0,80 per persona per notte.
SEGRETERIA ORGANIZZATIVA
Nadirex International srl
Congressi - Meeting - Comunicazione
Via Riviera, 39 - 27100 Pavia, ITALY
Tel. +39 0382 525735-14 - Fax +39 0382 525736
Cell. +39 347 8589333 - E-mail: [email protected] - www.nadirex.com
11
SI RINGR A ZIA
sponsor unico della manifestazione
SEGRETERIA
ORGANIZZATIVA
Nadirex International srl
Congressi - Meeting - Comunicazione
Via Riviera, 39 - 27100 Pavia, ITALY
Tel. +39 0382 525735-14
Fax +39 0382 525736
E-mail: [email protected]
www.nadirex.com