4Th Annual EMSCO meeting
Transcript
4Th Annual EMSCO meeting
FACULTY GENERAL INFORMATION Lionel Adès Paris, France Enrico Balleari Genoa, Italy Nicolas Bonadies Bern, Switzerland Mario Cazzola Pavia, Italy Fatiha Chermat Paris, France Daniela Cilloni Orbassano-TO, Italy Dominic Culligan Aberdeen, United Kingdom Matteo Giovanni Della Porta Rozzano-MI, Italy Pierre Fenaux Paris, France Michaela Fontenay Paris, France Ulrich Germing Düsseldorf, Germany Aristoteles Giagounidis Düsseldorf, Germany Daniela Gioia Alessandria, Italy Silke Gloaguen Dresden, Germany Katharina Götze München, Germany Detlef Haase Göttingen, Germany Olivier Hermine Paris, France Wolf-Karsten Hofmann Mannheim, Germany Anna Jonasova Prague, Czech Republic Austin Kulasekararaj London, United Kingdom Alessandro Levis Alessandria, Italy Luca Malcovati Pavia, Italy Hind Medyouf Frankfurt, Germany Esther Oliva Reggio Calabria, Italy Francesco Onida Milan, Italy Sophie Park Grenoble, France Uwe Platzbecker Dresden, Germany Valeria Santini Florence, Italy Guillermo Sanz Valencia, Spain Rebekka Schneider-Kramann Aachen, Germany Eric Solary Villejuif, France Ana Belén Valencia Martínez Florence, Italy Aart Anne van de Loosdrecht Amsterdam, Netherlands Norbert Vey Marseille, France Francesca Vinchi Heidelberg, Germany Maria Teresa Voso Rome, Italy Meeting Venue Aula Magna Università degli Studi di Firenze Piazza S. Marco, 4 50121 – Florence, Italy Scientific Committee Prof. Valeria Santini (Florence – IT) Prof. Pierre Fenaux (Paris – FR) Prof. Uwe Platzbecker (Dresden – GER) 4Th Annual EMSCO meeting Official Language English. Badge All registered participants and speakers will be given a badge which they must wear to be admitted to the scientific sessions. Attendance certificate A certificate will be given to all participants at the end of the meeting. Changes Parts of the program may be changed without notice. Organizing Secretariat Studio E.R. Congressi Via Marconi, 36 40122 Bologna - Italy Phone +39 051 4210559 Fax +39 051 4210174 E-mail: [email protected] www.ercongressi.it Scientific Secretariat EMSCO European MDS Studies Coordination Office supported by GWT-TUD GmbH Blasewitzer Str. 43 01307 Dresden - Germany Phone +49 351 259 33100 Fax +49 351 259 33111 E-mail: [email protected] www.emsco.eu With the unrestricted support of: Florence September 29-30, 2016 Aula Magna, University of Florence 29th September 2016 30th September 2016 14.30 OPENING CEREMONY General Introduction P. Fenaux, U. Platzbecker, V. Santini Session 1: Greetings by Rector Magnificus of the University of Florence Prof. L. Dei Session 1: EMSCO TRIAL UPDATE Chairs: P. Fenaux, V. Santini 14.35 DACOTA trial – status update F. Chermat, D. Gioia, S. Gloaguen 14.50 EUROPE trial – status update F. Chermat, S. Gloaguen 15.05 SAMBA trial – status update L. Ades, U. Platzbecker 15.20 Vosaroxin trial – status update L. Ades, U. Platzbecker CLINICAL TRIALS – EVIDENCE AND WORK IN PROGRESS Chairs: W.K. Hofmann, N.Vey 08.45 Update on the WHO classification in MDS – impact on trial design? L. Malcovati 09.00 (Genetic) markers for response and outcome to treatment with HMAs A.B. Valencia 09.15(Genetic) markers for response and outcome to treatment with ESA S. Park 09.30(Genetic) markers for response and outcome to HSCT M.G. Della Porta 09.45 Comparison of TPO-agonists in MDS E. Oliva 10.00 Secondary MDS: biology and therapeutic options M.T. Voso 10.15 Response to EPO E. Balleari Session 2a: CLINICAL TRIALS IN THE EU – OVERVIEW – PART 1 10.30 Coffee break 15.45 Italy V. Santini Session 2: Chairs: A. Levis, A.A. van de Loosdrecht, G. Sanz 16.00 France P. Fenaux 16.15 Germany A. Giagounidis 16.30 Coffee break Session 2b: CLINICAL TRIALS IN THE EU – OVERVIEW – PART 2 Chairs: L. Ades, U. Germing 16.50 Spain G. Sanz 17.05 Netherlands A.A. van de Loosdrecht 17.20 Czech Republic A. Jonasova 17.35 Switzerland N. Bonadies 17.50 Great Britain D. Culligan 18.05 Update on the revision of IWG response criteria L. Ades, P. Fenaux, A. Giagounidis, A. van de Loosdrecht, U. Platzbecker, V. Santini 18.15 Closing Remarks 20.00 Dinner TRANSLATIONAL STUDIES IN MDS POTENTIAL NEW TARGETS? Chairs: M. Cazzola, O. Hermine 10.50 How to target innate immunity in MDS? A. Kulasekararaj 11.05 The target of lenalidomide in MDS K. Götze 11.20 How to target inflammation in MDS R. Schneider-Kramann 11.35 Iron overload and vascular damage in mice (and men?) F. Vinchi 11.50 Results of Biofer study D. Cilloni 12.05 Roundtable discussion (all) 12.30 Lunch break Session 3: TRANSLATIONAL STUDIES IN MDS BIOLOGY AND TARGETS Chairs: M. Fontenay, D. Haase 13.30 Update on MDS mouse models H. Medyouf 13.45 Novel targets in MDS N. Vey 14.00 Pathophysiologic commonalities of thalassemia and RS-MDS O. Hermine 14.15 Insights into biology and prognosis of CMML E. Solary 14.30 Proposal for improved diagnosis and classification of CMML F. Onida 14.45 Roundtable discussion (all) 15.30 Adjourn