Europass Curriculum Vitae - Facoltà di Farmacia e Medicina
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Europass Curriculum Vitae - Facoltà di Farmacia e Medicina
Europass Curriculum Vitae Personal information First name(s) / Surname(s) Address(es) Telephone(s) Fax(es) E-mail Nationality Vincenzo Cuomo Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy 064454295 0649912480 [email protected] Italian Date of birth 03/12/1947 Gender male Occupational field Academia: full professor of Pharmacology (SSD BIO/14 Pharmacology) Work experience Assistant Professor, Institute of Pharmacology, University of Bari (Italy) Associate Professor, Institute of Pharmacology, University of Bari (Italy) Full Professor of Pharmacology, Institute of Pharmacology, University of Bari (Italy) Full Professor of Pharmacology, Dept. of Physiology and Pharmacology “V. Erspamer” Sapienza University of Rome 1973-1980 1980-1985 1986-2001 2001-present Visiting Professor, Institute of Toxicology, University of Zurich (Switzerland) and Dept. of Environmental Health Sciences, Johns Hopkins University (Baltimore, USA) 1979-1983 Occupation or position held Full Professor of Pharmacology, Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Italy Page 1/6 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Main activities and responsibilities Research activity Author of 244 publications on scientific journals and of several books and book chapters in the field of Neuropharmacology and Neurotoxicology. Dr Cuomo’s research activity has been mainly addressed to the evaluation of neurobehavioural, neurochemical and electrophysiological changes produced in rats by the developmental exposure to psychotherapeutic agents, drugs of abuse, and environmental chemicals. More recently he has explored the effects of chemicals influencing the endocannabinoid system in animal models of psychiatric disorders. In particular, he has explored the role of endocannabinoids and related lipid signals in the modulation of cognitive functions, feeding behaviour, anxiety and mood tone. All these researches have been funded by WHO, EPA, Italian Ministry of Education, National Research Council, Italian Ministry of Health. Other scientific activities and Professional Memberships 1986-1992 Secretary General of the Italian Society of Toxicology 1989-1995 Member of the Steering Committee of WHO/IPCS (Collaborative Study on Neurotoxicology Assessment) 1989-1993 Member of the European Interlaboratory Study Group on Behavioral Teratology 1991-1993 Member of the Executive Committee of EUROTOX (European Society of Toxicology) 1993-1996 Member of the Executive Committee of the Italian Society of Neurosciences 1995-1997 Member of the Executive Committee of the Italian Society of Pharmacology 1997-1999 General Secretary of the Italian Society of Pharmacology 1999-2003 President of the Italian Society of Pharmacology 2006-2010 Member of National University Council 2001-present Director PhD School of Toxicology 2001-2006 Director Department of Pharmacology of Natural Substances and General Physiology 2008-present Member of the Scientific Committee of the School of Pharmacy, Tor Vergata Univ., Rome Member of the editorial board of the following international scientific journals: Neurotoxicology and Teratology (Plenum Press, N.Y, USA) Neuroscience Research Communications (J. Wiley & Sons Ltd., Chichester, Sussex, England) Pharmacological Research (Co-Editor) (Academic Press, London, England) Toxicology Letters (Elsevier Science, Amsterdam, The Netherlands) Asian Journal of Pharmacological Sciences World Journal of Pharmacology (WJP, Ocean International Center, No. 62 Dongsihuan Zhonglu, Chaoyang District, Beijing 100025, China). World Journal of Clinical Pediatrics (Ocean International Center, No.62 Dongsihuan Zhonglu, Chaoyang District, Beijing 100025, China) European Journal of Neurodegenerative diseases Referee for several International scientific journal of the field of Pharmacology and Toxicology and referee for several national and international grant programs Name and address of employer Sector Dept. of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy SSD BIO/14 Pharmacology Education and training 1971, Degree in Medicine and Surgery (full score), University of Napoli, Italy 1971-1973 Fellowship at the Institute of Pharmacology, University of Bari (Italy) 1976 Specialization in Hygiene and Preventive Medicine, University of Bari, Italy Personal skills and competences Mother tongue(s) Italian Other language(s) English Self-assessment Understanding Listening European level (*) C2 Page 2/6 - Curriculum vitae of Surname(s) First name(s) Italian Speaking Reading C2 Italian Spoken interaction C2 Italian For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Writing Spoken production C2 Italian C2 Italian C1 English C1 English C1 English C1 English C1 English (*) Common European Framework of Reference for Languages Additional information Teaching activities: Course of Chemotherapy, Faculty of Medicine, University of Bari (1975-1980) Course of Pharmacology, Faculty of Medicine, University of Bari (1980-1982) Course of Pharmacology (Associate Professor), Faculty of Medicine, University of Bari (1982-1985) Course of Pharmacology (Full Professor), Faculty of Medicine, University of Bari (1986-2001) Courses of Pharmacology and Toxicology in various Schools for Medical Specializations, Faculty of Medicine, University of Bari (1986-2001) Coordinator f the PhD program “Clinical Pharmacology and Medical Therapy” University of Bari (19882001) Course of Toxicology, School for Medical Specialization in Pharmacology, Faculty of Medicine, University of Bari (1989-2001) Course of Pharmacology and Pharmacotherapy, Master Course in Medicinal Chemistry, Faculty of Pharmacy, University of Rome “La Sapienza” (2001-2003) Coordinator of the PhD program in Toxicology and Pharmacology (previously Pharmacology, Pharmacognosy and Toxicology), University of Rome “La Sapienza” (2001-present) Course of Pharmacology, Master Course in Environmental Toxicology, Faculty of Pharmacy, University of Rome “La Sapienza” (2003-2004) Course of Pharmacology II, Master Course in Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Rome “La Sapienza” (2003-2004) Course of Pharmacology and Pharmacotherapy I and II, Master Course in Medicinal Chemistry, Faculty of Pharmacy, University of Rome “La Sapienza” (2004-2005) Course of Pharmacology and Pharmacotherapy, Master Course in Medicinal Chemistry, Faculty of Pharmacy and Medicine, University of Rome “La Sapienza” (2005-present) Collaborations: Institut fur Toxikologie der Universitat Zurich, Schweiz (Prof. G. Zbinden – Dr. J. Elsner) Dept. of Environmental Health Sciences, Division of Toxicology, Johns Hopkins University, Baltimore, USA (Prof. Z. Annau) Dept. of Zoology, King's College, University of London, England (Dr. G.D. Sales) Dept. of Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA (Prof. R.J. Barfield) Dept. of Experimental Psychology, University of Cambridge, London, England (Prof. T. W. Robbins) Dept. of Neurobiology, Babraham Institute, Cambridge, England (Dr. K. Kendrick) Dept. of Pharmacology, University of Nottingham, England (Prof. C.A. Marsden) Laboratoire de Toxicologie et d’Hygiene Appliquée, Université Bordeaux II, France (Prof. E.E. Creppy) Dept. of Pharmacology, University of California, Irvine (Prof. D. Piomelli) Dept. of Neurobiology & Behavior, University of California, Irvine (Prof. J. McGaugh) Department of Pharmacology and Anatomy, Rudolf Magnus Institute, Utrecht, the Netherlands (Prof. L.J.M.J. Vanderschuren) Department of Psychiatry, McGill University, Montreal, Canada (Prof. G. Gobbi) Receiving Every day (Monday-Friday) upon appointment fixed by email Annexes Scientific Publication Selected 30 publications among those published in the last 15 years (IF=impact factor) 1. TRABACE L, ZOTTI M, MORGESE MG, TUCCI P, COLAIANNA M, SCHIAVONE S, AVATO P, CUOMO V. Estrous cycle affects the neurochemical and neurobehavioral profile of carvacroltreated female rats. Toxicol Appl Pharmacol 2011, 255(2):169-75 (IF 3.993) 2. COLAIANNA M, TUCCI P, ZOTTI M, MORGESE MG, SCHIAVONE S, GOVONI S, CUOMO V, TRABACE L, Soluble B-Amyloid1-42: a critical player in producing behavioural and biochemical changes evoking depressive-related state?, Br J Pharmacol 2010, 159(8):1704-15 (IF 4.925) 3. GAETANI S, FU J, CASSANO T, DIPASQUALE P, ROMANO A, RIGHETTI L, CIANCI S, LACONCA L, GIANNINI E, SCACCIANOCE S, MAIRESSE J, CUOMO V, PIOMELLI D, The fatinduced satiety factor OEA suppresses feeding through central release of oxytocin, J Neurosci 2010, 30(24):8096–8101, (IF 7.271) Page 3/6 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 4. SORCE S, SCHIAVONE S, TUCCI P, COLAIANNA M, JAQUET V, CUOMO V, DUBOIS-DAUPHIN M, TRABACE L, KRAUSE KH, The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses, J Neurosci 2010, 30(34):11317-25 (IF 7.271) 5. CAMPOLONGO P, ROOZENDAAL B, TREZZA V, CUOMO V, ASTARITA G, FU J, MCGAUGH JL, PIOMELLI D, The fat-induced satiety factor OEA enhances memory consolidation. Proc Natl Acad Sci U S A 2009, 106(19): 8027-31 (IF 9.771) 6. CAMPOLONGO P, TREZZA V, PALMERY M, TRABACE L, CUOMO V Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations, Int Rev Neurobiol 2009 85:117-33 (IF 4.017) 7. GAETANI S, DIPASQUALE P, ROMANO A, RIGHETTI L, CASSANO T, PIOMELLI D, CUOMO V The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs. Int Rev Neurobiol 2009, 85:57-72 (IF 4.017) 8. CAMPOLONGO P, ROOZENDAAL B, TREZZA V, HAUER D, SCHELLING G, MCGAUGH JL, CUOMO V. Endocannabinoids in the rat basolateral amygdala enhance memory consolidation: involvement of the glucocorticoid system. Proc Natl Acad Sci USA 2009, 106(12):4888-93 (IF 9.771) 9. SCHWARTZ GJ, FU J, ASTARITA G, XIAOSONG L, GAETANI S, CAMPOLONGO P, CUOMO V, PIOMELLI D The lipid messenger OEA links dietary fat intake to satiety. Cell Metab 2008, 8(4):2818 (IF 18.207) 10. TREZZA V, CAMPOLONGO P, CASSANO T, MACHEDA T, DIPASQUALE P, CARRATÙ MR, GAETANI S, CUOMO V Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats. Psychopharmacology 2008, 198(4):529-37 (IF 3.817) 11. CASTALDO P, MAGI S, GAETANI S, CASSANO T, FERRARO L, ANTONELLI T, AMOROSO S, CUOMO V. Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex. Neuropharmacology 2007, 53(3):369-78 (IF 4.677) 12. GOBBI G, BAMBICO FR, MANGIERI R, BORTOLATO M, CAMPOLONGO P, SOLINAS M, CASSANO T, MORGESE MG, DEBONNEL G, DURANTI A, TONTINI A, TARZIA G, MOR M, TREZZA V, GOLDBERG SR, CUOMO V, PIOMELLI D, Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci USA 2005, 102(51):18620-5 (IF 9.771) 13. CAMPOLONGO P, TREZZA V, CASSANO T, GAETANI S, MORGESE MG, UBALDI M, SOVERCHIA L, ANTONELLI T, FERRARO L, MASSI M, CICCOCIOPPO R, CUOMO V. Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats. Addict Biol 2007, 12(3-4): 48595 (IF 4.152) 14. BORTOLATO M, CAMPOLONGO P, MANGIERI RA, SCATTONI ML, FRAU R, TREZZA V, LA RANA G, RUSSO R, CALIGNANO A, GESSA GL, CUOMO V, PIOMELLI D. Anxiolytic-like properties of anandamide transport inhibitor AM404. Neuropsychopharmacology 2006, 31(12):2652-9 (IF 6.685) 15. ANTONELLI T, TOMASINI MC, TATTOLI M, CASSANO T, TANGANELLI S, FINETTI S, MAZZONI E, TRABACE L, STEARDO L, CUOMO V, FERRARO L Prenatal exposure to the CB1 receptor agonist WIN 55,212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring. Cereb Cortex 2005, 15(12):2013-20 (IF 6.844) 16. COSTA LG, STEARDO L, CUOMO V Structural effects and neurofunctional sequelae of developmental exposure to psychotherapeutic drugs: experimental and clinical aspects. Pharmacol Rev 2004, 56(1):103-47 (IF 18.861) 17. SARTIANI L, CERBAI E, LONARDO G, DE PAOLI P, TATTOLI M, CAGIANO R, CARRATU’ MR, CUOMO V, MUGELLI A. Prenatal exposure to carbon monoxide affects postnatal cellular electrophysiological maturation of the rat heart: a potential substrate for arrhythmogenesis in infancy. Circulation 2004, 109(3):419-23 (IF 14.429) 18. KATHURIA S, GAETANI S, FEGLEY D, VALINO F, DURANTI A, TONTINI A, MOR M, TARZIA G, LA RANA G, CALIGNANO A, GIUSTINO A, TATTOLI M, PALMERY M, CUOMO V, PIOMELLI D, Page 4/6 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Modulation of anxiety through blockade of anandamide hydrolysis, Nat Med 2003, 9(1):76-81 (IF 25.430) 19. MEREU G., FÀ M., FERRARO L., CAGIANO R., ANTONELLI T., TATTOLI M., GHIGLIERI V., TANGANELLI S., GESSA G.L., CUOMO V. Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release, Proc Natl Acad Sci USA 2003, 100(8):4915-20 (IF 9.771) 20. GAETANI S, CUOMO V, PIOMELLI D, Anandamide hydrolysis: a new target for anti-anxiety drugs? Trends Mol Med 2003, 9(11):474-8 (IF 10.308) 21. TRABACE L, CASSANO T, LOVERRE A, STEARDO L, CUOMO V, CHF2819: Pharmacological profile of a novel acetylcholinesterase inhibitor, CNS Drug Rev 2002, 8(1):53-69 (IF 3.492) 22. CAGIANO R, CASSANO T, COLUCCIA A, GAETANI S, GIUSTINO A, STEARDO L, TATTOLI M, TRABACE L, CUOMO V, Genetic factors involved in the effects of developmental low-level alcohol induced behavioral alterations in rats, Neuropsychopharmacology 2002, 26(2):191-203 (IF 6.685) 23. VACCARI A, RUIU S, SABA P, FA’ M, CAGIANO R, COLUCCIA A, MEREU G, STEARDO L, TATTOLI M, TRABACE L, CUOMO V, Prenatal low level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats, Int J Neuropsychopharmacol 2001, 4(3):219-222 (IF 4.699) 24. TATTOLI M, CAGIANO R, GAETANI S, GHIGLIERI V, GIUSTINO A, MEREU G, TRABACE L, CUOMO V, Neurofunctional effects of developmental alcohol exposure in alcohol-preferring and alcohol-nonpreferring rats, Neuropsychopharmacology 2001, 24(6):691-705 (IF 6.685) 25. MEREU G, CAMMALLERI M, FA’ M, FRANCESCONI W, SABA PL, TATTOLI M, TRABACE L, VACCARI A, CUOMO V, Prenatal exposure to a low concentration of carbon monoxide disrupts hippocampal long-term potentiation in rat offspring, J Pharmacol Exp Ther 2000, 294(2):728-34 (IF 4.017) 26. STEARDO L, MONTELEONE P, TRABACE L, CANNIZZARO C, MAJ M, CUOMO V, Serotonergic modulation of rat pineal gland activity: in vivo evidence for a 5-HT2C receptor involvement, J Pharmacol Exp Ther 2000, 295(1):266-73 (IF 4.017) 27. TRABACE L, CASSANO T, STEARDO L, PIETRA C, VILLETTI G, KENDRICK KM, CUOMO V, Biochemical and neurobehavioral profile of CHF2819, a novel orally active acethylcholinesterase inhibitor for Alzheimer’s disease, J Pharmacol Exp Ther 2000, 294(1):187-94 (IF 4.017) 28. CAGIANO R, ANCONA D, CASSANO T, TATTOLI M, TRABACE L, CUOMO V, Effects of prenatal exposure to low concentrations of carbon monoxide on sexual behaviour and mesolimbic dopaminergic function in rat offspring, Br J Pharmacol 1998,125(4):909-15 (IF 4.925) 29. STEARDO L, MONTELEONE P, d’ISTRIA M, SERINO I, MAJ M, CUOMO V, receptor modulation of noradrenergic-stimulated pineal melatonin biosynthesis in rats, J Neurochem 1996, 67, 287-293 (IF 4.337) 30. CUOMO V, DE SALVIA MA, PETRUZZI S, ALLEVA E, Appropriate endpoints for the characterization of behavioral changes in developmental toxicology, Environ Health Perspec 1996, 104, 307-315 (invited review). (IF 6.087) Page 5/6 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Selected Textbooks (Chapters, etc.) ROSSI F, CUOMO V, RICCARDI C “Farmacologia. Principi di base e applicazioni Terapeutiche” Ed. Minerva Medica, Torino, seconda edizione 2011 CUOMO V, STEARDO L, Assunzione di sostanze di abuso durante la gestazione, MEDICINA CLINICA. Basi Biologiche Diagnostica Terapia, C.G. Ed. Med. Scient., Torino, 2003, 4(cap. XXIX), pp. 1-20. COURT J, CUOMO V, ERIKSSON P, PERRY E, PICKLES A, RAY D, RODIER P, STANTON M, TAYLOR, VARGHA-KHADEM F, Perinatal developmental neurotoxicity, Medical Research Concil, Institute for Environment and Health Publish., Report 4, Leichester, UK, pp. 1-84, 1996. ZBINDEN G, CUOMO V, RACAGNI G, WEISS B Application of Behavioural Pharmacology in Toxicology", (Eds.), Raven Press, N.Y., pp. 161-172, 1983 RACAGNI G, MOCCHETTI I, DE ANGELIS L, BARALDI M, CUOMO V, In vivo effects of typical and atypical antidepressants on brain noradrenergic system: behavioural correlations, Adv. Biochem. Psychopharmacol., Raven Press, N.Y., 31, 185-197, 1982. Page 6/6 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010