Transcatheter Pulmonary Valve implantation

Transcript

Transcatheter Pulmonary Valve implantation
Transcatheter Pulmonary Valve
implantation
The role of imaging for patients selection
and procedure monitoring
Mario Carminati - IRCCS Policlinico San Donato, Milan
 Policlinico San Donato IRCCS
Melody®
Transcatheter Pulmonary Valve
• 18mm Contegra modified-bovine jugular vein with valve segment
• NuMed Platinum Iridium Stent
– 28 mm length
– Crimped down to 6mm, re-expanded 18mm up to 22mm
• Balloon Expandable system
 Policlinico San Donato IRCCS
Melody® Indications
• Extend the functional life of
the RV-PA conduit
• Restore & maintain pulmonary
valve competence
• Relieve conduit stenosis
without inducing regurgitation
 Policlinico San Donato IRCCS
RVOT disfunction: target population
ROSS
Others
11%
TRUNCUS
8%
9%
TGA+VSD+PS
32%
11%
29%
PA + VSD
 Policlinico San Donato IRCCS
FALLOT
Patient Selection
 RV outflow tract obstruction (RVOTO)
– RV systolic pressure ≥ 2/3 of systemic
 Moderate to severe regurgitation (PR)
– Impaired exercise capacity (<65% of predicted)
– Significant RV dilatation / dysfunction
 Policlinico San Donato IRCCS
Patient evaluation
•
•
•
•
Clinical/functional (CPEX)
ECG/Holter
Echocardiography
Cardiac MRI
 Policlinico San Donato IRCCS
 Policlinico San Donato IRCCS
Echocardiography
 Policlinico San Donato IRCCS
Echocardiography
 Policlinico San Donato IRCCS
Severe Tricuspid regurgitation
ooooooooooooooooo
 Policlinico San Donato IRCCS
ooooooooooooooooo
 Policlinico San Donato IRCCS
Magnetic resonance imaging
•
•
•
•
RVOT morphology
Pulmonary trunk/branches anatomy
RV size and function
Evaluation of pulmonary
stenosis/regurgitation (regurgitant fraction)
 Policlinico San Donato IRCCS
Magnetic resonance imaging
• RVOT morphology (suitability?)
X
?
?
 Policlinico San Donato IRCCS
?
Courtesy dr Schievano
MR + 3D reconstruction
 Policlinico San Donato IRCCS
MR-Angiogram
 Policlinico San Donato IRCCS
Distal conduit stenosis
 Policlinico San Donato IRCCS
Melody
 Policlinico San Donato IRCCS
LPA severe hypoplasia
 Policlinico San Donato IRCCS
LPA severe hypoplasia
 Policlinico San Donato IRCCS
Melody
 Policlinico San Donato IRCCS
CT as an alternative to MR
 Policlinico San Donato IRCCS
RVOT too large????
 Policlinico San Donato IRCCS
RVOT sizing
 Policlinico San Donato IRCCS
 Policlinico San Donato IRCCS
Extensive conduit calcification
 Policlinico San Donato IRCCS
Prestenting + Melody
 Policlinico San Donato IRCCS
 Policlinico San Donato IRCCS
VD, 32 y, TGA+VSD+PS, Rastelli with RV-PA homograft 18
Conduit severe stenosis and calcification
 Policlinico San Donato IRCCS
Prestenting with CP covered stent
 Policlinico San Donato IRCCS
Incomplete stent expansion
 Policlinico San Donato IRCCS
Post-dil with Mullins high pressure balloon
 Policlinico San Donato IRCCS
Final Angio post Melody implantation
 Policlinico San Donato IRCCS
RV-PA conduit / coronaries
 Policlinico San Donato IRCCS
Balloon inflation and simultaneous aortogram
 Policlinico San Donato IRCCS
 Policlinico San Donato IRCCS
Matrix 25 mm conduit: stenosis and regurgitation
 Policlinico San Donato IRCCS
 Policlinico San Donato IRCCS
PA angiogram
 Policlinico San Donato IRCCS
26 Sapien implant
 Policlinico San Donato IRCCS
Final PA angiogram
 Policlinico San Donato IRCCS
Pre-procedure evaluation
• MR is the gold standard for:
* RVOT morphology
* RV volumes/function
 Policlinico San Donato IRCCS
Intraprocedure monitoring
• Angiography is the gold standard
(more sofisticated technology as rotational
angiography may be very helpful)
* Very little role, if any, of echo
 Policlinico San Donato IRCCS
Thank you for your attention!
Mario Carminati
 Policlinico San Donato IRCCS

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