blood12514toc 5..7

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2 APRIL 2015 x VOLUME 125, NUMBER 14
CONTENTS
COVER FIGURE
The image features human platelet generation in megakaryocytes and endothelial
cells in a silk film culture system. See the article by Di Buduo et al on page 2254.
INSIDE BLOOD COMMENTARIES
2179
Recurrent pregnancy loss: drop the heparin needles…
Marc A. Rodger
Comment on Pasquier et al, page 2200
2180
Endogenous miR-29a regulates HSC function in mammals
Ryan M. O’Connell
Comment on Hu et al, page 2206
2181
Platelet biogenesis wears silkworm cocoons
Koji Eto
Comment on Di Buduo et al, page 2254
2183
Ironing out the role of Toll-like receptors
Karin E. Finberg
Comment on Guida et al, page 2265
PERSPECTIVES
2185
Established and theoretical factors to consider in assessing the red cell storage lesion
James C. Zimring
EVIDENCE-BASED FOCUSED REVIEW
2191
The role of thrombolytic therapy in pulmonary embolism
Tzu-Fei Wang, Alessandro Squizzato, Francesco Dentali, and Walter Ageno
CLINICAL TRIALS AND
OBSERVATIONS
2200
Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter
randomized double-blind placebo-controlled trial
Elisabeth Pasquier, Luc de Saint Martin, Caroline Bohec, Céline Chauleur, Florence Bretelle,
Gisèle Marhic, Grégoire Le Gal, Véronique Debarge, Frédéric Lecomte, Christine Denoual-Ziad,
Véronique Lejeune-Saada, Serge Douvier, Michel Heisert, and Dominique Mottier
HEMATOPOIESIS AND
STEM CELLS
2206
miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a
Wenhuo Hu, James Dooley, Stephen S. Chung, Dhruva Chandramohan, Luisa Cimmino,
Siddhartha Mukherjee, Christopher E. Mason, Bart de Strooper, Adrian Liston,
and Christopher Y. Park
IMMUNOBIOLOGY
2217
The mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate
immune responses
Mir Munir A. Rahim, Peter Chen, Amelia N. Mottashed, Ahmad Bakur Mahmoud,
Midhun J. Thomas, Qinzhang Zhu, Colin G. Brooks, Vicky Kartsogiannis, Matthew T. Gillespie,
James R. Carlyle, and Andrew P. Makrigiannis
LYMPHOID NEOPLASIA
2228
Epstein-Barr virus LMP2A suppresses MHC class II expression by regulating the
B-cell transcription factors E47 and PU.1
Jiun-Han Lin, Ju-Yin Lin, Ya-Ching Chou, Mei-Ru Chen, Te-Huei Yeh, Chung-Wu Lin,
Sue-Jane Lin, and Ching-Hwa Tsai
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CONTINUED ON vi
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2239
A practical approach to the diagnosis of systemic amyloidoses
Carlos Fernández de Larrea, Laura Verga, Patrizia Morbini, Catherine Klersy, Francesca Lavatelli,
Andrea Foli, Laura Obici, Paolo Milani, Gian Luca Capello, Marco Paulli, Giovanni Palladini,
and Giampaolo Merlini
MYELOID NEOPLASIA
2245
Morgana acts as an oncosuppressor in chronic myeloid leukemia
Augusta Di Savino, Cristina Panuzzo, Stefania Rocca, Ubaldo Familiari, Rocco Piazza,
Sabrina Crivellaro, Giovanna Carrà, Roberta Ferretti, Federica Fusella, Emilia Giugliano,
Annalisa Camporeale, Irene Franco, Barbara Miniscalco, Juan Carlos Cutrin, Emilia Turco,
Lorenzo Silengo, Emilio Hirsch, Giovanna Rege-Cambrin, Carlo Gambacorti-Passerini,
Pier Paolo Pandolfi, Mauro Papotti, Giuseppe Saglio, Guido Tarone, Alessandro Morotti,
and Mara Brancaccio
PLATELETS AND
THROMBOPOIESIS
2254
Programmable 3D silk bone marrow niche for platelet generation ex vivo and
modeling of megakaryopoiesis pathologies
Christian A. Di Buduo, Lindsay S. Wray, Lorenzo Tozzi, Alessandro Malara, Ying Chen,
Chiara E. Ghezzi, Daniel Smoot, Carla Sfara, Antonella Antonelli, Elise Spedden,
Giovanna Bruni, Cristian Staii, Luigi De Marco, Mauro Magnani, David L. Kaplan,
and Alessandra Balduini
RED CELLS, IRON, AND
ERYTHROPOIESIS
2265
A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia
Claudia Guida, Sandro Altamura, Felix A. Klein, Bruno Galy, Michael Boutros, Artur J. Ulmer,
Matthias W. Hentze, and Martina U. Muckenthaler
THROMBOSIS AND
HEMOSTASIS
2276
Both platelet- and endothelial cell–derived ERp5 support thrombus formation in
a laser-induced mouse model of thrombosis
Freda H. Passam, Lin Lin, Srila Gopal, Jack D. Stopa, Lola Bellido-Martin, Mingdong Huang,
Barbara C. Furie, and Bruce Furie
2286
Inter-a inhibitor protein and its associated glycosaminoglycans protect against
histone-induced injury
Hala Chaaban, Ravi S. Keshari, Robert Silasi-Mansat, Narcis I. Popescu,
Padmaja Mehta-D’Souza, Yow-Pin Lim, and Florea Lupu
2297
Crucial role for the VWF A1 domain in binding to type IV collagen
Veronica H. Flood, Abraham C. Schlauderaff, Sandra L. Haberichter, Tricia L. Slobodianuk,
Paula M. Jacobi, Daniel B. Bellissimo, Pamela A. Christopherson, Kenneth D. Friedman,
Joan Cox Gill, Raymond G. Hoffmann, Robert R. Montgomery, and the Zimmerman Program
Investigators
BLOOD WORK
2305
“Atypical” macrophages
Jonathan Bloch and Sabine Blum
CORRESPONDENCE
2306
Ibrutinib and idelalisib synergistically target BCR-controlled adhesion in MCL and
CLL: a rationale for combination therapy
Martin F. M. de Rooij, Annemieke Kuil, Arnon P. Kater, Marie José Kersten, Steven T. Pals,
and Marcel Spaargaren
2309
CALR-mutated essential thrombocythemia evolving to chronic myeloid leukemia with
coexistent CALR mutation and BCR-ABL translocation
Irina Bonzheim, Barbara Mankel, Peter Klapthor, Janine Schmidt, Tanja Hinrichsen,
Oliver Wachter, Falko Fend, and Leticia Quintanilla-Martinez
vi
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2311
Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia:
a retrospective analysis of the EWOG-MDS study group
Annamaria Cseh, Charlotte M. Niemeyer, Ayami Yoshimi, Michael Dworzak, Henrik Hasle,
Marry M. van den Heuvel-Eibrink, Franco Locatelli, Riccardo Masetti, Markus Schmugge,
Ute Groß-Wieltsch, Andrea Candás, Andreas E. Kulozik, Lale Olcay, Meinolf Suttorp,
Ingrid Furlan, Brigitte Strahm, and Christian Flotho
OTHER DEPARTMENTS
ib
Classifieds
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viii
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