Cristina Benatti Date and place of birth
Transcript
Cristina Benatti Date and place of birth
Cristina Benatti Date and place of birth: Citizenship: Professional address: Education October 27, 1976, Modena Italian Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy Tel.: +390592055383 Fax.: +390592055376 e-mail: [email protected] Research technician (section:Neuroscience) (area TECNICA, TECNICO/SCIENTIFICA ED ELABORAZIONE DATI) Department of Life Sciences, University of Modena and Reggio Emilia 2012-present Research technician (section:Neuroscience) (area TECNICA, TECNICO/SCIENTIFICA ED ELABORAZIONE DATI) Department of Biomedical Sciences , University of Modena and Reggio Emilia October 2008-2012 Post-doc Fellow on the project: CHARACTERIZATION OF THE ROLE OF NEUROTROPHIC FACTORS IN MEDIATING STRESS EFFECTS IN THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION; at the Section of Pharmacology, Department of Biomedical Sciences, University of Modena and Reggio Emilia under the supervision of Prof. Nicoletta Brunello ([email protected]). May 2007- May 2008 Ph.D. defending the thesis: DEVELOPMENT OF ANALYTICAL METHODOLOGIES TO DETECT BIOLOGICALLY ACTIVE COMPOUNDS IN PHARMACOLOGICAL STUDIES March 2007 Doctoral Fellow (graduate student) in Pharmaceutical Sciences, Section of Molecular Pharmacology, University of Modena and Reggio Emilia, Prof. Carlo Parenti ([email protected]); Section of Pharmacology, Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, via Campi 183, Modena. 2004-2007 Specialization in Pharmaceutical Research Methods. October 2003 - May 2002 State exam for the profession of Pharmacist. December 2002 Apprentice student to "Della Speranza Pharmacy" (Chiessi Attilio) Carpi. May 2002-December 2003 Master in Chemistry and Pharmaceutical Technology (full marks cum laude) defending the thesis: NEONATAL PERSISTENT INFLAMMATION ALTERS PAIN RESPONSE AND NMDA RECEPTOR EXPRESSION IN ADULT MICE May 2002 Cristina Benatti Undergraduate student in the Laboratory of Molecular Pharmacology of the Department of Pharmaceutical Science at the University of Modena and Reggio Emilia. under the supervision of Prof. Nicoletta Brunello ([email protected]); Section of Pharmacology, Department of Biomedical Sciences, University of Modena and Reggio Emilia, via Campi 287, Modena. February 2001 Graduation from High School (full marks) July 1995 Research interests Technical profile Educational activity 2 Long term effect of neonatal pain on future responsiveness to noxious stimuli and possible long term molecular effect of a persistent neonatal inflammation; Post-receptor targets involved in the molecular mechanisms underlying the effect of antidepressants; Animal models (transgenic and behavioural) of depression to study molecular mechanisms of antidepressant drugs; Effect of environmental stress (chronic and acute) on cAMP dependent gene expression. 1. Molecular techniques: - PREPARATION AND ANALYSIS OF DNA: resolution and recovery of small to large amount of plasmid DNA in prokaryotes; DNA extraction from tissue, blood and tail; RTPolimerase Chain Reaction (RT-PCR); cDNA cloning; digestion of DNA with restriction endonucleases, DNA ligations. - PREPARATION AND ANALYSIS OF RNA: total RNA extraction from tissue, blood and tissue culture cells; analysis of RNA structure and synthesis by Ribonuclease Protection Assay; In Situ hybridization. - ANALYSIS OF PROTEINS: total and fractional (citosolic and nuclear) proteins extraction from tissue, blood and tissue culture cells; electrophoretic separation of proteins; detection of protein on Blot Transfer Membranes with Western Blotting; immunocytochemistry, ELISA. 2. Behavioral analysis: Restraint stress paradigm; Anxiety test: Elevated Plus Maze, Open Field; Hot Plate Test; Tests of depression: Acute and chronic escape deficit Forced swim test; Tail suspension test. 3. Animal care and surgery: Animal treatment: oral, i.p. and s.c administration in rats and mice; Dissection of cerebral areas and minor peripheral microsurgery; intracardical perfusion. Blood sampling. 4. HPLC analysis: Determination of fluoxetine and its metebolite norfluoxetine in serum and cerebral cortex using HPLC chromatography and UV detector. Determination of serotonin and its metebolite 5-Hydroxy indole acetic acid in cerebral cortex using HPLC chromatography and UV detector. Intracerebral Microdialysis. Computer skills: Elaborate knowledge of Windows, Microsoft Office (Excel, PowerPoint presentations) , Winword, Internet Explorer, programs of statistical analysis (i.e. Origin, SPSS), elaboration and analysis of images. Language skills: Italian (mother tongue), good English and scholastic French. Academic years 2003-2014: assistant lecturer: course of “Pharmacology” (degree in Chemistry and Pharmaceutical Technology, teacher: prof. Brunello Nicoletta): “Asthma management”, “Pathophysiology of the Renal Cristina Benatti System and Diuretic Drugs”, “Antivirals”, “Antimalarics”, “Pharmacology of the Purinergic System”, “Drugs affecting coagulations”; course of “Special Pharmacology” (degree Biotecnology, teacher: prof. Brunello Nicoletta): “Migraine”; course of “Laboratory of Cellular And Molecular Pharmacology“ (degree Biotecnology, teacher: dott. Fabio Tascedda): “Intracerebral Microdialysis”. Publications 1) Cannazza G, Di Stefano A, Mosciatti B, Braghiroli D, Pinnen F, Sozio P, Benatti C and Parenti C DETECTION OF LEVODOPA, DOPAMINE AND ITS METABOLITES IN RAT STRIATUM DIALYSATES FOLLOWING PERIPHERAL ADMINISTRATION OF L-DOPA PRODRUGS BY MEAN OF HPLC-EC. Journal Of Pharmaceutical And Biomedical Analysis. Vol. 36, No. 5, pages 1079-1084 (2005). 2) Brunello N, Alboni S, Capone G, Benatti C, Blom JM, Tascedda F, Kriwin P, Mendlewicz J. ACETYLSALICYLIC ACID ACCELERATES THE ANTIDEPRESSANT EFFECT OF FLUOXETINE IN THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION. Int Clin Psychopharmacol. 2006 Jul;21(4):219-25. 3) Alboni S, Capone G, Benatti C, Tascedda F, Blom JMC, Mendlewicz J, Brunello N. P.2.d.012 BEHAVIOURAL AND MOLECULAR EFFECTS OF THE COMBINED TREATMENT FLUOXETINE PLUS ACETYLSALICYLIC ACID IN A RAT MODEL OF DEPRESSION. European Neuropsychopharmacology 2006; 16, S4,S339. 4) Alboni S, Blom JMC, Corsini D, Benatti C, Capone G, Ferraguti C, Barden N, Tascedda F, Brunello N. EFFECTS OF ACUTE STRESS ON BRAIN-DERIVED NEUROTROPHIC FACTOR IN THE HIPPOCAMPUS OF TRANSGENIC MOUSE MODEL OF DEPRESSION. European Neuropsychopharmacology, 2006, 16,S1, S33-S34. 5) Capone G, Alboni S, Benatti C. P.2.a.014 RAPID EFFECT OF ESCITALOPRAM IN A BEHAVIOURAL MODEL OF DEPRESSION: THE CHRONIC ESCAPE DEFICIT. European Neuropsychopharmacology, 2006; 16, S4, S290. 6) Capone G, Alboni S, Benatti C, Tascedda F, Blom JMC, Mendlewicz J, Brunello N. ACETYLSALICYLIC ACID ACCELERATES THE ANTIDEPRESSANT EFFECT OF FLUOXETINE IN A RAT MODEL OF DEPRESSION. European Neuropsychopharmacology. 2006;16,S1, S61. 7) Blom JMC, Benatti C, Alboni S, Capone G, Ferraguti C, Brunello N, Tascedda F. EARLY POSTNATAL CHRONIC INFLAMMATION PRODUCES LONG-TERM CHANGES IN PAIN BEHAVIOR AND N-METHYL-D-ASPARTATE RECEPTOR SUBTYPE GENE EXPRESSION IN THE CENTRAL NERVOUS SYSTEM OF ADULT MICE. Journal of Neuroscience Research; Volume 84, Issue 8, Pages 1789-1798, December 2006. 8) Brunello N, Benatti C. FARMACOLOGIA E NEUROBIOLOGIA NEI DISTURBI D’ANSIA E NELLA DEPRESSIONE. Facts News & Views; Volume 2, Pagine 12-17, Ottobre 2007 (Italian). 9) Brunello N, Alboni S, Benatti C, Corsini D, Capone G, Tascedda F, Mendlewicz J. S.15.03 COMBINED EFFECT OF ANTIDEPRESSANT AND ANTI-INFLAMMATORY DRUGS IN AN ANIMAL MODEL OF DEPRESSION. European Neuropsychopharmacology 2007 3 Cristina Benatti Oct; 17 S4,S198. 10) Alboni S; Corsini D; Caggia F; Benatti C; Capone G; Barden N; Blom J.M.C; Tascedda F; Brunello N; IMPAIRED STRESS-INDUCED REGULATION OF BRAIN DERIVED NEUROTROPHIC FACTOR EXPRESSION IN HIPPOCAMPUS OF GLUCOCORTICOID RECEPTOR IMPAIRED MICE: MODEL OF DEPRESSION. Int J Neuropsychopharmacol. 2008 Jul;11(S1):S125. 11) Caggia F; Valensisi C; Alboni S; Benatti C; Corsini D; Ferrari F; Tagliafico E; Mendlewicz J; Brunello N; Tascedda F MICROARRAY ANALYSIS OF THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION: EFFECTS OF ESCITALOPRAM TREATMENT IN HIPPOCAMPUS. Int J Neuropsychopharmacol. 2008 Jul;11(S1):S124. 12) Benatti C, Alboni S, G. Capone, D. Corsini, Caggia F, J.M.C. Blom, Tascedda F, Brunello N. P.1.03 MOLECULAR EFFECTS OF SUBCHRONIC AND CHRONIC TREATMENT WITH ESCITALOPRAM IN THE RAT CENTRAL NERVOUS SYSTEM. European Neuropsychopharmacology. 2008; 18,S1, s4-s5. 13) Caggia F, Valensisi C, Alboni S, Benatti C, Corsini D, Ferrari F, Tagliafico E, Mendlewicz J, Tascedda F, Brunello N. P.2.04 MICROARRAY ANALYSIS IN HIPPOCAMPUS OF RATS TREATED WITH ESCITALOPRAM IN THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION. European Neuropsychopharmacology 2009 Mar; 19, S1,S36-S37. 14) Valensisi C, Caggia F, Alboni S, Benatti C, F. Ferrari, Mendlewicz J, J. Blom, N. Brunello, Tascedda F. P.1.33 GENE EXPRESSION PROFILE OF THE HIPPOCAMPUS OF A BEHAVIOURAL MODEL OF DEPRESSION. European Neuropsychopharmacology. 2009 Mar; 19,S1, S29. 15) Benatti C, Alboni S, Capone G, Corsini D, Caggia F, Brunello N, Tascedda F and Blom JMC. EARLY NEONATAL INFLAMMATION AFFECTS ADULT PAIN REACTIVITY AND ANXIETY RELATED TRAITS IN MICE: GENETIC BACKGROUND COUNTS. International Journal Of Developmental Neuroscience; 2009 Nov;27(7):661-8. 16) Alboni S*, Benatti C*, Capone G, Corsini D, Caggia F, Tascedda F, Mendlewicz J, Brunello N. TIME-DEPENDENT EFFECTS OF ESCITALOPRAM ON BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) AND NEUROPLASTICITY RELATED TARGETS IN THE CENTRAL NERVOUS SYSTEM OF RATS. Eur J Pharmacol. 2010 Sep 25;643(2-3):180-7 (* co-author) 17) Alboni S, Montanari C, Benatti C, Blom JMC, Brunello N, Caggia F, Guidotti G, Garibaldi Marcondes MC, Sanchez-Alavez M, Conti B, Tascedda F. CONSTITUTIVE AND LPS-REGULATED EXPRESSION OF INTERLEUKIN-18 RECEPTOR BETA VARIANTS IN THE MOUSE BRAIN. Brain Behav Immun. 2011 Mar;25(3):483-93 18) Alboni S, Tascedda F, Corsini D, Benatti C; Caggia F, Capone G, Barden N, Blom JMC, Brunello N. STRESS INDUCES ALTERED CRE/CREB PATHWAY ACTIVITY AND BDNF EXPRESSION IN THE HIPPOCAMPUS OF GLUCOCORTICOID RECEPTOR-IMPAIRED MICE. Neuropharmacology. 2011 Jun; 60(7-8):1337-46. 19) Benatti C, Alboni S, Caggia F, Montanari C, Brunello N, Tascedda F, Blom JMC. 4 Cristina Benatti CENTRAL EFFECTS OF A LOCAL INFLAMMATION IN THREE COMMONLY USED MOUSE STRAINS WITH A DIFFERENT ANXIOUS PHENOTYPE. Behav Brain Res. 2011 May 23;224(1):23-34. 20) Alboni S, Benatti C, Montanari C, Tascedda F, Pariante CM, Brunello N. P.2.b.002 INTERFERON-ALPHA EXPOSURE INCREASES THE EXPRESSION OF ENZYMES OF THE KYNURENINE PATHWAY AND INDUCES APOPTOSIS IN A MODEL OF HUMAN NEURONS. European Neuropsychopharmacology, 2012 Oct; 22, S2, S242. 21) Benatti C, Valensisi C, Blom JM, Alboni S, Montanari C, Ferrari F, Tagliafico E, Mendlewicz J, Brunello N, Tascedda F. TRANSCRIPTIONAL PROFILES UNDERLYING VULNERABILITY AND RESILIENCE IN RATS EXPOSED TO AN ACUTE UNAVOIDABLE STRESS. J Neurosci Res. 2012 Nov;90(11):2103-15. 22) Alboni S, Gibellini L, Montanari C, Benatti C, Benatti S, Tascedda F, Brunello N, Cossarizza A, Pariante CM. N-ACETYL-CYSTEINE PREVENTS TOXIC OXIDATIVE EFFECTS INDUCED BY IFN-Α IN HUMAN NEURONS. Int J Neuropsychopharmacol. 2013 Sep;16(8):1849-65. 23) Alboni S.*, Benatti C.*, Montanari C., F. Tascedda, N. Brunello CHRONIC ANTIDEPRESSANT TREATMENTS RESULTED IN ALTERED EXPRESSION OF GENES INVOLVED IN INFLAMMATION IN THE RAT HYPOTHALAMUS. Eur J Pharmacol. 2013 Dec 5;721(1-3):158-67. (* co-author) 24) Alboni S., Benatti C., Montanari C., Benatti S., Iarini M., Tascedda F., Cannazza G., Pariante C.M., Brunello N. INTERFERON ALPHA EXPOSURE INCREASES THE EXPRESSION OF THE ENZYMES BELONGING TO THE KYNURENINE PATHWAY IN AN IN VITRO MODEL OF HUMAN NEURONS: SH-SY5Y CELLS. Neuroimmune Pharmacology. Volume 8, Number 5. December 2013. 25) Alboni S, Montanari C, Benatti C, Sanchez-Alavez M, Rigillo G, Blom JM, Brunello N, Conti B, Pariante MC, Tascedda F. INTERLEUKIN 18 ACTIVATES MAPKS AND STAT3 BUT NOT NF-ΚB IN HIPPOCAMPAL HT-22 CELLS. Brain Behav Immun. 2014 Aug;40:8594. 26) Benatti C, Alboni S, Blom JM, Gandolfi F, Mendlewicz J, Brunello N, Tascedda F. BEHAVIOURAL AND TRANSCRIPTIONAL EFFECTS OF ESCITALOPRAM IN THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION. Behav Brain Res. 2014 Oct 1;272:121-30. 27) Nasi M, Alboni S, Pinti M, Tascedda F, Benatti C, Benatti S, Gibellini L, De Biasi S, Borghi V, Brunello N, Mussini C, Cossarizza A. SUCCESSFUL TREATMENT OF HIV-1 INFECTION INCREASES THE EXPRESSION OF A NOVEL, SHORT TRANSCRIPT FOR IL-18 RECEPTOR α CHAIN. J Acquir Immune Defic Syndr. 2014 Nov 1;67(3):254-7. 28) Alboni S, Benatti C, Tascedda F, Brunello N. P.2.a.012 Co-administration of fluoxetine with acetylsalicylic acid, but not flurbiprofen or celecoxib, for one week shows an antidepressant-like effect. European Neuropsychopharmacology, Volume 25, Supplement 2, September 2015, Pages S381-S382 29) Benatti C, Blom JMC, Rigillo G, Alboni S, Zizzi F, Torta R, Brunello N, Tascedda F. 5 Cristina Benatti DISEASE-INDUCED NEUROINFLAMMATION AND DEPRESSION accepted in a Special Issue for CNS & Neurological Disorders - Drug Targets (CNSND-DT) Volume 15, Issue 4, 1 May 2016, Pages 414-433 30) Francesconi W, Sanchez-Alavez M, Berton F, Alboni S, Benatti C, Mori S, Nguyen W, Zorrilla E, Moroncini G, Tascedda F, Conti B. The pro-inflammatory cytokine Interleukin 18 regulates feeding by acting on the Bed Nucleus of the Stria Terminalis. The Journal of Neuroscience; May 4;36(18):5170-80. doi: 10.1523/JNEUROSCI.3919-15.2016. 31) Caraci F, Tascedda F, Merlo S, Benatti C, Spampinato SF, Munafò A, Leggio GM, Nicoletti F, Brunello N, Drago F, Sortino MA, Copani A. Fluoxetine Prevents Aβ1-42Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factorβ1. Front Pharmacol. 2016 Oct 25;7:389. 32) Alboni S, Bonaventura MV, Benatti C, Giusepponi ME, Brunello N, Cifani C. Hypothalamic expression of inflammatory mediators in an animal model of binge eating. Behav Brain Res. 2016 Oct 28. pii: S0166-4328(16)30950-0. doi: 10.1016/j.bbr.2016.10.044. Awards Winner ECNP Travel Awards 2005 at the 18th ECNP Congress 2005 - Amsterdam, The Netherlands presenting the poster: C. Benatti, S. Alboni, C. Ferraguti, F. Tascedda, J.M.C. Blom, N. Brunello NEONATAL PERSISTENT INFLAMMATION ALTERS PAIN RESPONSE AND NMDA RECEPTOR EXPRESSION IN ADULT MICE. 18th ECNP Congress, Amsterdam, October 22-26, 2005. Winner “Jorge Perez” Awards 2008 at XVI Congress of the Italian Society of Neuropsycopharmacology (SINPF) presenting the poster: Benatti C., Alboni S., Capone G., Corsini D., Caggia F. , Tascedda F., Brunello N. EFFETTI MOLECOLARI DI UN TRATTAMENTO CRONICO E SUBCRONICO CON ESCITALOPRAM NEL SISTEMA NERVOSO CENTRALE DI RATTO. XVI Congresso Della Società Italiana Di Neuropsicofarmacologia; Milano, 24-26 giugno, 2008. Oral communications Benatti C., BEHAVIORAL AND MOLECULAR CHARACTERIZATION OF THREE MOUSE STRAIN WITH DIFFERENT ANXIOUS PHENOTYPE. XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia” Cagliari 25 Settembre 2010. Benatti C., A 7 DAY TREATMENT WITH FLUOXETINE PLUS ASPIRIN OR ESCITALOPRAM DOWNREGULATES IL-6 HYPOTHALAMIC EXPRESSION IN THE CHRONIC ESCAPE DEFICIT MODEL OF DEPRESSION. Convegno Monotematico Sif: Mood Disorders: From Neurobiology To Novel Therapeutic Strategies, Modena March, 20th- 21st, 2014 POSTER PRESENTATIONS AS FIRST AUTHOR Benatti C., Alboni S., Montanari C, Tascedda F., Brunello N., Blom J.M.C. CENTRAL EFFECTS OF A LOCAL INFLAMMATION ON THREE COMMONLY USED MOUSE STRAINS WITH A DIFFERENT ANXIOUS PHENOTYPE; 35° Congresso Nazionale della Società Italiana di Farmacologia Bologna, 14-17 Settembre 2011 Benatti C., Alboni S., Montanari C, Tascedda F., Brunello N., Blom J.M.C. CENTRAL EFFECTS OF A LOCAL INFLAMMATION ON THREE COMMONLY USED MOUSE STRAINS WITH A DIFFERENT ANXIOUS PHENOTYPE; NEXT STEP2 la giovane ricerca avanza”, Milano; 24 giugno 2011. Benatti C., Alboni S., Caggia F., Montanari C., Brunello N., Tascedda F., Blom J.M.C.. BEHAVIORAL AND MOLECULAR CHARACTERIZATION OF THREE MOUSE STRAIN WITH DIFFERENT ANXIOUS PHENOTYPE. XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia” Cagliari 22-25 Settembre 2010. 6 Cristina Benatti Benatti C., S. Alboni, G. Capone, D.Corsini, F. Caggia, N. Brunello, F. Tascedda and J.M.C. Blom. EARLY NEONATAL INFLAMMATION AFFECTS ADULT PAIN REACTIVITY AND ANXIETY RELATED TRAITS: GENETIC BACKGROUND COUNTS. 38th Annual Meeting Society for Neuroscience, Washington, DC Nov. 15–19, 2008. Benatti C., Alboni S., Capone G., Corsini D., Caggia F. , Tascedda F., Brunello N. EFFETTI MOLECOLARI DI UN TRATTAMENTO CRONICO E SUBCRONICO CON ESCITALOPRAM NEL SISTEMA NERVOSO CENTRALE DI RATTO. XVI Congresso Della Società Italiana Di Neuropsicofarmacologia; Milano, 24-26 giugno, 2008. Benatti C., Alboni S., Capone G., Corsini D., Caggia F., Tascedda F., Blom J. M.C., Brunello N. MOLECULAR EFFECTS OF SUBCHRONIC AND CHRONIC TREATMENT WITH ESCITALOPRAM IN THE RAT CENTRAL NERVOUS SYSTEM. ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, March 6-9 March 2008 Benatti C., S. Alboni, G. Capone, D. Corsini, F. Tascedda, N. Brunello,J.M.C. Blom. NEONATAL PERSISTENT INFLAMMATION DIFFERENTIALLY AFFECTS ADULT PAIN RESPONSE IN TWO DIFFERENT MOUSE STRAINS. 37th Annual Meeting Society for Neuroscience, San Diego, California | November 3 – 7, 2007 Benatti C., Alboni S., Capone G., Caggia F., Valensisi C., Tascedda F., Brunello N., Blom J.M.C. EARLY POSTNATAL CHRONIC INFLAMMATION ALTERS PAIN RESPONSE AND ANXIETY BEHAVIOUR IN ADULT MICE. National Congress of Italian Society of Neuroscience (SINS) Verona, September 27-30,2007. Benatti C., Alboni S., Capone G., Corsini D., Caggia F., Tascedda F., Blom J. M.C., Brunello N. ESCITALOPRAM ALTERS BDNF, CREB AND CARF GENE EXPRESSION IN DISCRETE RAT BRAIN AREAS. Società Italiana di Farmacologia 33° Congresso Nazionale Cagliari, 6-9 Giugno 2007 Benatti C., Alboni S., Capone G., Corsini D., J.M.C. Blom, Tascedda F., Brunello N. RUOLO DELLA NEUROTROFINA BDNF NELLA RISPOSTA RAPIDA AL TRATTAMENTO CON ANTIDEPRESSIVI IN UN MODELLO COMPORTAMENTALE DI DEPRESSIONE. XV Congresso Della Società Italiana Di Neuropsicofarmacologia; Genova, 06-09 giugno, 2006. Benatti C., S. Alboni, C. Ferraguti, F. Tascedda, J.M.C. Blom, N. Brunello NEONATAL PERSISTENT INFLAMMATION ALTERS PAIN RESPONSE AND NMDA RECEPTOR EXPRESSION IN ADULT MICE. 18th ECNP Congress, Amsterdam, October 22-26, 2005. Benatti C.,Alboni S., Capone G., Corsini D., Ferraguti C., Nanni G., Tascedda F., Brunello N.. EXPRESSION OF BRAIN DERIVED NEUROTROPHIC FACTOR IN A BEHAVIORAL MODEL OF DEPRESSION. Società Italiana di Farmacologia 32° Congresso Nazionale Napoli, June 1-4, 2005. Benatti C., S. Alboni, C. Ferraguti, F. Tascedda, N. Brunello, J.M.C. Blom. REACTIVITY TO NOCICEPTION AND BRAIN DERIVED NEUROTROPHIC FACTOR EXPRESSION IN ADULT MICE THAT EXPERIENCED NEONATAL PERIPHERAL INFLAMMATION. XIV Congresso Della Società Italiana Di Neuropsicofarmacologia; Bologna, June 1-4, 2004. Benatti C., N. Brunello, J.M.C. Blom, S. Alboni, C. Ferraguti, F. Tascedda. REACTIVITY TO NOCICEPTION AND NMDA RECEPTOR EXPRESSION IN ADULT MICE THAT EXPERIENCED NEONATAL PERIPHERAL INFLAMMATION. XIII Congresso Della Società Italiana Di Neuropsicofarmacologia; Milan, July 9-12 2002. 7 Cristina Benatti ABSTRACTS AS COLLABORATOR 8 -Benatti S., S. Alboni, C. Benatti, G. Cannazza, N. Brunello, F. Tascedda (Modena) Ascorbate counteracts neurotoxic effect induced by 3-hydroxykynurenine in an in vitro model of human neurons. Convegno Monotematico Sif: Mood Disorders: From Neurobiology To Novel Therapeutic Strategies, Modena March, 20th- 21st, 2014 -S. Alboni, M.V. Micioni Di Bonaventura, C. Novi, C. Benatti, N. Brunello, R . Ciccocioppo, C. Cifani Regulation of the expression of the IL-18\IL-18R system in the hypothalamus of a rat model of binge eating: effect of the phase of the estrous cycle. 36° Congresso Nazionale Della Società Italiana Di Farmacologia Torino 23-26 ottobre 2013. -S. Alboni, C. Benatti, C. Montanari, F. Tascedda, C.M. Pariante, N. Brunello, Italy Interferon-alpha exposure increases the expression of enzymes of the kynurenine pathway and induces apoptosis in a model of human neurons. 25th ECNP Congress 13-17 October 2012, Vienna -Montanari C., Benatti C., Alboni S., Tascedda F., Brunello N. Effects of chronic antidepressant treatments on expression of inflammatory biomarkers in the rat hypothalamus; NEXT STEP2 la giovane ricerca avanza”, Milano; 24 giugno 2011. -Alboni S., Montanari C., Benatti C., Brunello N., Conti B., Tascedda F. LPS-INDUCED CYTOKINE RESPONSES: role of IL-18; “NEXT STEP2 la giovane ricerca avanza”, Milano; 24 giugno 2011. -Montanari C., Benatti C., Alboni S., Tascedda F., Brunello N. Effects of chronic antidepressant treatments on expression of inflammatory biomarkers in the rat hypothalamus; 35° Congresso Nazionale della Società Italiana di Farmacologia Bologna, 14-17 Settembre 2011 -Alboni S., Benatti C., Montanari C., Valensisi C., Tascedda F., Pariante C., Brunello N.. The kynurenine pathway in human neuroblastoma sh-sy5y cells: regulation by pro-inflammatory cytokines. 35° Congresso Nazionale della Società Italiana di Farmacologia Bologna, 14-17 Settembre 2011 -Valensisi C, Benatti C, Alboni S, Ferrari F, Caggia F, Gandolfi F, Montanari C, Bicciato S, Brunello N, Tascedda F Transcriptional profiles associated with vulnerability and resilience to stress in a behavioural model of depression Néoneurogénèse Premier colloque aquitain de la plasticité cérébrale, Bordeaux, 30 September-1 October 2010 -Alboni S., Montanari C., Benatti C., Caggia F., Valensisi C., Blom J.M.C., Tascedda F., Conti B., Brunello N. Constitutive and immune stress-regulated expression of interleukin-18 system in the mouse brain. XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia” Cagliari 22-25 Settembre 2010. -Montanari C, Alboni S., Benatti C., Valensisi C.,Tascedda F., Conti B., Brunello N., Characterization of the interleukin-18 receptor beta and its small variant in the mouse brain. Next Step, la giovane ricerca avanza; Milano 1 luglio 2010. -Gandolfi F., Valensisi C., Ferrari F., Benatti C., Roncaglia E., Brunello N., Tascedda F., Bicciato S. A combined approach for analyzing exon-profiling data from functionally relevant areas of the central nervous system. Recomb 2010; Lisbon August 12-15, 2010 -Alboni S., Corsini D., Caggia F., Benatti C., Capone G., Barden N., Blom J.M.C., Tascedda F., Brunello N. Impaired stress-induced regulation of Brain Derived Neurotrophic Factor expression in hippocampus of Glucocorticoid Receptor impaired mice: Model of depression. XXVIth CINP Congress, Munich, July 13-17, 2008. -Caggia F., Valensisi C., Alboni S., Benatti C., Corsini D., Ferrari F., Tagliafico E., Mendlewicz J., Brunello N., Tascedda F. Microarray analysis of the chronic escape deficit model of depression: Effects of escitalopram treatment in hippocampus. XXVIth CINP Congress, Munich, July 13-17, 2008. -Valensisi C., Caggia F., Alboni S., Benatti C., Corsini D., Blom J. , Mendlevicz J. , Brunello N., Tascedda F. Profilo di espressione genica in ippocampo in un modello animale di depressione: il deficit di fuga cronico XVI Congresso Della Società Italiana Di Neuropsicofarmacologia; Milano, 24-26 giugno, 2008. -Caggia F., Valensisi C., Alboni S., Benatti C., Corsini D., Ferrari F., Tagliafico E., Mendlewicz J., Tascedda F., Brunello N. Utilizzo dei Gene Chip Rat Exon Array nel modello comportamentale del deficit di fuga cronico: effetto del trattamento con escitalopram. XVI Congresso Della Società Italiana Di Neuropsicofarmacologia; Milano, 24-26 giugno, 2008. -Alboni S., Benatti C., Capone G., Corsini D., Caggia F., Mendlewicz J., Tascedda F., Brunello N. Effetti di una settimana di trattamento con escitalopram o escitalopram più aspirina nel modello comportamentale di depressione del deficit di fuga cronico. XVI Congresso Della Società Italiana Di Neuropsicofarmacologia; Milano, 24-26 giugno, 2008. -S. Alboni, D. Corsini, G. Capone, C. Benatti, F. Caggia, A. E. West, N. Brunello, N. Barden, J. Blom, F. Tascedda Regulation of transcritional activity in hippocampus of Glucocorticoid Receptor impaired transgenic mice: effect of restraint stress 37th Annual Meeting Society for Neuroscience, San Diego, California | November 3 – 7, 2007 -Caggia F., Alboni S., Capone G., Benatti C., Corsini D., Brunello N., Tascedda F. Pharmacological regulation of Calcium Responsive Transcription Factor, CaRF, in the rat hippocampus National Congress of Italian Society of Neuroscience (SINS) Verona, September 27-30,2007. Cristina Benatti -Corsini D., Alboni S., Blom J. M.C., Benatti C., Capone G., Caggia F., Barden N., Brunello N., Tascedda F. Effects of restraint stress on the hippocampus of Glucocorticoid Receptor impaired transgenic mice National Congress of Italian Society of Neuroscience (SINS) Verona, September 27-30,2007. -Alboni S., Benatti C., Capone G., Caggia F., Corsini D., Tascedda F., Mendlewicz J., Brunello N. Acetyl salicylic acid increases the response of escitalopram in a rat model of depression. Società Italiana di Farmacologia 33° Congresso Nazionale Cagliari, 6-9 Giugno 2007 -Corsini D., Alboni S., Blom J.M.C., Benatti C., Caggia F., Barden N., Brunello N., Tascedda F. Regulation of transcriptional activity in hippocampus of Glucocorticoid Receptor impaired transgenic mice: effects of restraint stress. Società Italiana di Farmacologia 33° Congresso Nazionale Cagliari, 6-9 Giugno 2007 -Capone G., Alboni S., Benatti C., Corsini D., Tascedda F., Brunello N. 1) Rapid effect of escitalopram in a behavioural model of depression: the chronic escape deficit. 2) Behavioural and molecular effects of escitalopram in a model of depression: the chronic escape model. 19th ECNP Congress, Paris, September 16-20, 2006. -S. Alboni, G. Capone, C. Benatti, F. Tascedda, J.M.C. Blom, J. Mendlewicz, N. Brunello. Behavioural and molecular effects of the combined treatment fluoxetine plus acetylsalicylic acid in a rat model of depression. 19th ECNP Congress, Paris, September 16-20, 2006. N. Brunello, S. Alboni, G. Capone, C. Benatti, F. Tascedda, J.M.C. Blom , J. Mendlewicz. Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in a rat model of depression. ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, March 9 - 12, 2006 -S.Alboni, J.M.C.Blom, D.Corsini, C.Benatti, G.Capone, C.Ferraguti, N.Barden, F.Tascedda, N.Brunello. Effects of acute restraint stress on Brain–Derived Neurotrophic Factor expression in the hippocampus of transgenic mouse model of depression. ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, March 9 - 12, 2006 -S. Alboni, G. Capone, C. Benatti, F. Tascedda, N. Brunello, J. Mendlewicz. Nuovi approcci sperimentali per il potenziamento dell’attività dei farmaci antidepressivi. XV Congresso Della Società Italiana Di Neuropsicofarmacologia; Genova, 06-09 giugno, 2006. Corsini D., Alboni S., Blom J.M.C., Benatti C., Caggia F., Capone G., Brunello N., Tascedda F. Regolazione della neurotrofina BDNF nell’ippocampo di animali sottoposti ad uno stress da restraint. XV Congresso Della Società Italiana Di Neuropsicofarmacologia; Genova, 06-09 giugno, 2006. -Alboni S, Barden N, Benatti C, Brunello N, Capone G, Corsini D, Ferraguti C, Tascedda F, Blom JMC. Acute restraint stress increases the expression of Brain-Derived Neurotrophic Factor in the hippocampus of a mouse model of depression. 35nd Annual Meeting Society for Neuroscience, Washington, DC, 12-16 November, 2005. -Brunello N.; Alboni S.; Benatti C.; Capone G.; Tascedda F.; Blom J.M.C.; Mendlewicz J. New combination therapies from animal to human. 18th ECNP Congress, Amsterdam, October 22-26, 2005. -G. Cannazza, D. Braghiroli, C. Benatti, C. Parenti. Development of immobilized ligand binding domain of the Glur2 receptor chromatographic stationary phases. Second Joint Italian-Swiss Meeting on Medicinal Chemistry, Modena, September 12-16, 2005. -Alboni S., Blom J.M.C. , Benatti C., Barden N., Brunello N. , Capone G., Ferraguti C., Tascedda F. Restraint stress increases the expression of Brain Derived Neurotrophic Factor in the hippocapus of a mouse model of depression. Società Italiana di Farmacologia 32° Congresso Nazionale Napoli, June 1-4, 2005. -S. Alboni, G. Capone, C. Benatti, F. Tascedda, N. Brunello. Expression of Brain Derived Neurotrophic Factor in a behavioral model of depression. XIV Congresso Della Società Italiana Di Neuropsicofarmacologia; Bologna, June 1-4, 2004. -Alboni S., Benatti C. Blom J.M.C. Brunello N. Ferraguti C. Tascedda F. Restraint stress increases the expression of Brain Derived Neurotrophic Factor in the hippocampus of a mice model of depression. XXIVth CINP Congress, Paris, June 20-24, 2004. -S. Alboni, C. Ferraguti, J. Vinet, C. Benatti, E. Avantaggiato, N. Brunello, F.Tascedda, J.M.C Blom. effects of immobilization stress on the hippocampus of transgenic mice expressing type II Glucocorticoid Receptor antisense ribonucleic acid. Società Italiana di Farmacologia 31° Congresso Nazionale Trieste, June 26-29 2003. -Joan M.C. Blom, F. Tascedda, C. Benatti, S. Alboni, C. Ferraguti and N. Brunello. Central NMDA receptor expression in adult mice that experienced neonatal peripheral inflammation is age and brain area specific. 32nd Annual Meeting Society for Neuroscience, Orlando, Florida November 2-7 2002 Attendance to congresses and workshops 2002 XIII Congresso della Società Italiana di di Neuropsicofarmacologia Milano, Italia. 2003 31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Italia. 2004 XXIVth CINP Congress, Paris, France. 2004 XIV Congresso della Società Italiana di Neuropsicofarmacologia, Bologna, Italia. 9 Cristina Benatti 2005 32° Congresso Nazionale della Società Italiana di Farmacologia, Napoli, Italia. 2005 Internationl Symposium Neuroplasticity, Neurotrophic Factors and Mood Disorders, Pisa, Italia 2005 Società Italiana di Farmacologia XI Convegno Monotematico: Neurofarmacologia e Neurobiologia delle Dipendenze, Bologna, Italia 2005 Nuove Frontiere Nello Studio Del Cervello Umano E Delle Sue Patologie; Modena, Italia. 2005 18th ECNP CONGRESS, Amsterdam, The Nederland 2006 XV congresso nazionale della Società Italiana di Neuropsicofarmacologia, Genova, Italia. 2007 National Congress of Italian Society of Neuroscience (SINS) Verona, September 2008 ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France. 2008 XVI Congresso della Società Italiana di Neuropsicofarmacologia, Milano, Italia 2010 XVII Congresso della Società Italiana di di Neuropsicofarmacologia Cagliari, Italia. 2011 35° Congresso Nazionale della Società Italiana di Farmacologia, Bologna, Italia. 2014 Società Italiana di Farmacologia Convegno Monotematico: Mood Disorders: From Neurobiology To Novel Therapeutic Strategies, Modena, Italia. Autorizzo al trattamento dei dati personali in conformità alla legge 675/96. Modena, 10 Cristina Benatti